Strip of 10 Units
Old MRP ₹158
MRP ₹148.12
₹118.5
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CompositionPolmanac Capsule 10 inhibitor NSAID used to treat osteoarthritis of the knee and hip. It targets inflammation and pain to improve mobility and quality of life, offering a gastric-friendly alternative to traditional NSAIDs.
Always follow your doctor's instructions for dosage. Inform them of any pre-existing conditions or ongoing medications and report any side effects immediately while continuing the prescribed treatment.
Polmanac Capsule 10 treats joint pain and inflammation in osteoarthritis, especially in the hips and knees. Its anti-inflammatory properties reduce pain and swelling, improving mobility and daily function.
Follow these instructions while taking Polmanac Capsule 10:
Swallow the capsule whole with a full glass of water.
Do not open, crush, or chew the capsule.
Take this medicine with food to reduce stomach upset.
Polmanac Capsule 10 is taken orally.
Polmanac Capsule 10 may cause headache, nausea, stomach pain, dizziness, heartburn, gas, constipation, and diarrhea.
Most side effects are temporary and generally harmless and resolve on discontinuing the use of Polmanac Capsule 10. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.
Here are some general guidelines for managing common side effects:
Nausea: Taking Polmanac Capsule 10 with food can help reduce feelings of sickness.
Heartburn: Avoid lying down for at least 30 minutes after taking this medicine to prevent stomach acid from flowing back into your food pipe.
Polmanac Capsule 10 contains polmacoxib (2 mg), which works on the body as follows:
Selective COX-2 Inhibition: Polmacoxib specifically targets and blocks the COX-2 enzyme in your body, which is responsible for producing inflammatory substances called prostaglandins.
Prostaglandin Reduction: By blocking the COX-2 enzyme, polmacoxib decreases the production of prostaglandins at sites of inflammation, helping to reduce pain, swelling, and inflammation in affected joints.
Gastrointestinal Protection: Unlike traditional NSAIDs that block both COX-1 and COX-2 enzymes, polmacoxib's selective action on COX-2 means it has less effect on the protective COX-1 enzyme in the stomach lining, potentially reducing the risk of stomach irritation.
Polmanac Capsule 10 is not recommended during pregnancy. If you are pregnant or planning to conceive, make sure to discuss this with your doctor before starting this medicine.
Caution is advised while taking Polmanac Capsule 10 if you are breastfeeding. It is best to consult your doctor before taking this medicine.
Avoid consuming alcohol while taking Polmanac Capsule 10. Alcohol may increase the risk of stomach problems, such as irritation or bleeding, when combined with this medicine.
Caution is advised while taking Polmanac Capsule 10 in case of mild to moderate liver impairment. It is not recommended for severe liver diseases. If you have liver problems, discuss them with your doctor before starting Polmanac Capsule 10.
Caution is advised before using Polmanac Capsule 10 if you have a history of kidney problems. Consult your doctor before taking this medicine.
Polmanac Capsule 10 may cause dizziness or headaches in some people. If you experience these side effects, avoid driving or operating heavy machinery until you feel better.
If you have allergies to polmacoxib, or other ingredients present in Polmanac Capsule 10, you should not take this medicine. Inform your doctor about all your allergies before starting this medicine.
Caution is advised while giving Polmanac Capsule 10 to children under 18 years of age. Always consult your doctor before giving any medicine to a child.
Older patients should take Polmanac Capsule 10 under medical supervision, as they may be more susceptible to side effects. Your doctor will guide you based on your health status.
Polmanac Capsule 10 interacts with the following medicines:
Anticoagulants: Medicines like warfarin and heparin may have enhanced effects when taken with this medicine, potentially increasing your risk of bleeding.
NSAIDs: Taking aspirin, ibuprofen, or diclofenac alongside Polmanac Capsule 10 may increase the risk of stomach bleeding and ulceration.
Diuretics: Polmanac Capsule 10 may reduce the effectiveness of water tablets such as furosemide and hydrochlorothiazide, potentially affecting kidney function.
Polmanac Capsule 10 interacts with the following diseases:
Cardiovascular Disease: This medicine may worsen existing heart conditions and increase the risk of heart attack or stroke in patients with heart problems.
Peptic Ulcers: This medicine may aggravate stomach ulcers and increase the risk of gastrointestinal bleeding in affected patients.
Kidney Disease: Polmanac Capsule 10 should be used cautiously, as it may further impair kidney function in patients with existing kidney problems.
Asthma: This medicine may trigger bronchospasm (narrowing of airways) in patients with bronchial asthma, particularly those with aspirin sensitivity.
The daily dose of Polmanac Capsule 10 should be taken as prescribed by your doctor. The dosage may vary based on your specific condition and how you respond to treatment. Follow your doctor's instructions carefully and never alter the prescribed amount.
Overdosing on Polmanac Capsule 10 may cause headaches, severe nausea, vomiting, stomach pain, dizziness, or heartburn. You might also experience increased gas, constipation, or diarrhoea. If you experience unusual symptoms after taking extra medicine, contact your doctor for advice.
If you forget to take a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed one and continue with your regular schedule. Never take extra medicine to make up for the missed dose.
Store at room temperature (not exceeding 30°C).
Keep away from direct sunlight and moisture.
Store in the original packaging to protect from environmental exposure.
Keep out of reach of children.
Do not use this medicine after the expiry date printed on the package.
Engage in low-impact exercises like swimming or cycling to strengthen muscles around affected joints without putting excessive stress on them, which can help manage osteoarthritis symptoms alongside your medicine.
Include foods rich in omega-3 fatty acids (such as fish) and antioxidants (like colourful vegetables) in your diet, as these may help reduce inflammation associated with osteoarthritis.
| Dosage Forms Available | Capsule |
| Habit Forming | No |
| Ailment | Osteoarthritis, joint pain |
| Drug Category | COX-2 inhibitor |
| Therapeutic Category | NSAID |
Polmanac Capsule 10 works by blocking an enzyme called cyclooxygenase-2 (COX-2). This reduces inflammation and pain in your joints by decreasing the production of substances that cause swelling.
This medicine is primarily used to manage symptoms of osteoarthritis, particularly in the knee and hip joints. It helps reduce pain and inflammation in these areas.
Yes, you should take this medicine with food. This helps reduce the chance of stomach upset or discomfort that sometimes occurs with this type of medicine.
Common side effects may include headache, nausea, dizziness, stomach pain, heartburn, constipation, or diarrhoea. These usually improve as your body adjusts to the medicine.
Some people may experience dizziness after taking this medicine. If you feel dizzy, avoid driving or operating machinery until you know how it affects you.
Always inform your doctor about all medicines you are taking. Polmanac Capsule 10 may interact with blood thinners, diuretics (water tablets), and certain other medicines.
Seek immediate medical attention if you experience chest pain, shortness of breath, or weakness. These could be signs of serious cardiovascular effects requiring urgent care.
Check out Editorial Policy
Sinha, S. D., Prasad, T. B., Konatham, B., Sriramadasu, S. C., Karmakar, A., Sharma, A. K., Verma, R., Devireddy, S. R., Bandi, M. R., & Panapakam, M. (2024). Polmacoxib 2mg in patients with mild to moderate idiopathic osteoarthritis of hip/knee. A randomized, double-anonymous study. Pain Management, 14(9), 497–506. https://doi.org/10.1080/17581869.2024.2427944
DrugBank. (n.d.). Polmacoxib. Retrieved 1 April 2025, from https://go.drugbank.com/drugs/DB12399
Easwaran, R., Mistry, U. K., Bhole, M., & Peethambaran, K. (2024). Polmacoxib: A Review of the Newer Non-steroidal Anti-inflammatory Drug in Osteoarthritis. Cureus, 16(4), e58446. https://doi.org/10.7759/cureus.58446
Lee, M., Yoo, J., Kim, J. G., Kyung, H. S., Bin, S. I., Kang, S. B., Choi, C. H., Moon, Y. W., Kim, Y. M., Han, S. B., In, Y., Choi, C. H., Kim, J., Lee, B. K., & Cho, S. (2017). A Randomized, Multicenter, Phase III Trial to Evaluate the Efficacy and Safety of Polmacoxib Compared with Celecoxib and Placebo for Patients with Osteoarthritis. Clinics in Orthopedic Surgery, 9(4), 439–457. https://doi.org/10.4055/cios.2017.9.4.439
Manjula, S., & Krishna Kumar, M. (2024). Expert perspectives on polmacoxib monotherapy in the management of osteoarthritis in Indian settings. International Journal of Research in Orthopaedics, 11(1), 118–123. https://doi.org/10.18203/issn.2455-4510.intjresorthop20243896
We, at Truemeds make a diligent attempt to deliver accurate, expert- drafted and thoroughly reviewed medicine related information to our consumers. However, it should, by no means, be considered a substitute for prescription from a certified doctor or a trustworthy doctor-patient relationship. In fact we detest any form of self medication without expert advice. The sole purpose of the information on our portal is to educate our consumers, which helps improve the communication between a doctor and a patient. The information by no means is complete in its entirety and should not be used to diagnose or treat any medical condition. No amount of information can replace the experience and expertise of a doctor, therefore his/her advice always holds priority and should be followed appropriately.
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