Loyzide M 80 Tablet Pr 15

Lloyd Healthcare Pvt.ltd

Strip of 15 Units

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Old MRP ₹155.8

MRP ~~₹146.06~~

₹124.15

₹9.74/Units

15% off

*MRP inclusive of all taxes

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Prescription required for this medicine

Store Below 30^o C

Composition

Gliclazide (80 Mg) + Metformin (500 Mg)

Loyzide M 80 Tablet Pr 15 is used to regulate blood sugar levels in adults with type 2 diabetes mellitus. It belongs to the anti-diabetic class of medicines and works effectively when combined with a healthy diet and regular physical activity to maintain stable glucose levels.

This medicine is not intended for type 1 diabetes, where insulin production is severely reduced or absent. Before starting the tablet, inform your doctor about any allergies, medical history, or ongoing treatments. Report side effects promptly, and continue the medicine as advised for consistent and effective blood sugar management.

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Loyzide M 80 Tablet Pr 15 is used in the management of:

Type 2 diabetes

Swallow Loyzide M 80 Tablet Pr 15 whole with a glass of water
Do not crush or chew the tablet, as this may affect the absorption of Loyzide M 80 Tablet Pr 15 in the body
Take Loyzide M 80 Tablet Pr 15 at a fixed time every day. This will maintain the levels of medication in the blood.

Loyzide M 80 Tablet Pr 15 should be taken orally.

The common side effects of Loyzide M 80 Tablet Pr 15 include:

Nausea
Diarrhoea
Vomiting
Gastric pain

Management Of Side Effects:

Most side effects are temporary and generally harmless, resolving upon discontinuation of Loyzide M 80 Tablet Pr 15. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

Here is how you can manage the side effects:

Nausea: Take the medicine with food and stay hydrated; if it persists, consult your doctor.
Diarrhoea: Drink plenty of fluids to prevent dehydration and inform your doctor if it continues.
Vomiting: Take small, frequent meals and stay hydrated; seek medical advice if vomiting is severe or persistent.
Gastric pain: Take the medicine with meals or antacids; consult your doctor if the pain worsens or does not subside.

Loyzide M 80 Tablet Pr 15 contains the following components:

Gliclazide (80 Mg): It belongs to the class of sulfonylureas that causes your body to produce more insulin. Due to the release of increased insulin from the pancreas, the blood glucose level gets lowered.
Metformin (500 Mg): It is a biguanide that decreases glucose production in the liver and improves insulin sensitivity in muscle and fat cells. The body can better use insulin to transport glucose into cells, reducing blood sugar levels. It also helps to lower the amount of glucose absorbed from the gut.

Pregnancy

Loyzide M 80 Tablet Pr 15 is not indicated during pregnancy. Consult your doctor for any queries.

Breastfeeding

Breastfeeding women are not recommended to take Loyzide M 80 Tablet Pr 15. It can pass into the nursing infant through breast milk. Before taking this tablet while breastfeeding, it is recommended to consult a doctor.

Alcohol

Intake of alcohol while taking Loyzide M 80 Tablet Pr 15 may lead to hypoglycemia. Consult your doctor before use.

Liver

Loyzide M 80 Tablet Pr 15 should be used cautiously in case of liver disease. Please consult your doctor for further advice.

Kidney

Loyzide M 80 Tablet Pr 15 should be used cautiously in case of kidney disease. Please consult your doctor for further advice.

Use In Driving And Operating Machinery

If you are taking Loyzide M 80 Tablet Pr 15 with other medications, it can cause low blood sugar levels. If you feel dizzy, weak, have increased sweating, have a fast heartbeat, and have vision disorders, do not use the machine or drive.

Allergy

If you are allergic to Loyzide M 80 Tablet Pr 15, gliclazide, metformin, or any of its constituents. Do not take it. To avoid allergic reactions, read the label and check the ingredients.

Children

The safety and effectiveness of this tablet in children have not been established. Consult your child’s doctor for further advice before using it.

Older Patients

Older patients with liver, kidney, and heart impairment should take Loyzide M 80 Tablet Pr 15 cautiously. They may also take other medications that can interact with this tablet. Inform your doctor and discuss your prescription medications before taking this medicine.

Drug-Drug Interactions

Loyzide M 80 Tablet Pr 15 can interact with medications, including:

Antihypertensive medications like captopril and enalapril, when taken with Loyzide M 80 Tablet Pr 15, can affect blood pressure levels.
Other anti-diabetic medications, when taken with this medication, may further lower the blood glucose level on taking Loyzide M 80 Tablet Pr 15.
Antifungal medications such as fluconazole, when taken with this medication, may further lower the blood glucose levels.
NSAIDs such as aspirin, when taken with Loyzide M 80 Tablet Pr 15, may further lower the blood glucose levels.
Anticoagulants such as warfarin, when taken with Loyzide M 80 Tablet Pr 15, may further lower the blood glucose levels.

Drug-Disease Interactions

Loyzide M 80 Tablet Pr 15 can interact with diseases, including:

Heart diseases: Patients with heart failure are more at risk of hypoxia. Therefore, regular monitoring of heart function is required while taking this tablet.
Severe kidney impairment: This tablet is excreted via the kidney. If you have reduced kidney function, your doctor may need to adjust the dosage of this tablet.
Liver disease: This tablet may cause abnormal liver function tests or liver disease such as hepatitis.
Lactic acidosis: This tablet may cause lactic acidosis as a side effect and worsen the existing condition.

Daily Dose

The recommended dose of Loyzide M 80 Tablet Pr 15 should be as per the prescription given to you by your doctor. The dosage may change based on individual factors such as the severity of the condition and response to treatment. It is essential to follow the prescribed dosage and should not exceed it without a doctor’s consultation.

Over Dose

If you or someone else takes excessive Loyzide M 80 Tablet Pr 15 by accident, it is essential to get immediate medical attention from your doctor or a nearby hospital in case you experience symptoms of overdose, such as dizziness, confusion, tremors, sweating, and increased heartbeat.

Missed Dose

If you forgot to take a dose of Loyzide M 80 Tablet Pr 15, take it as soon as you remember. However, avoid repeating the dose.

Store this medicine below 30ºC.
Protect it from light and moisture.
Keep Loyzide M 80 Tablet Pr 15 away from children.
Do not use this medicine after the expiry date has passed.

Incorporate foods with low glycemic index, such as green leafy vegetables, whole grains, berries, citrus fruits, chia seeds, bitter gourd, and extra virgin olive oil.
Limit your intake of processed and high-sugar foods, which can cause spikes in blood sugar levels.
Avoid refined sugar intake in any form. Instead, use natural sweeteners such as stevia, sugar alcohols, yacon syrup, allulose, and monk fruit sweeteners.
Engage in regular physical activity, which can help improve insulin sensitivity and blood sugar control.
Quit smoking, as smoking can increase the risk of complications associated with diabetes.
Watch your sodium intake and not exceed 5 gm daily to avoid heart conditions with diabetes.
Monitor your blood sugar levels regularly and stay connected with your doctor to adjust your treatment plan.

Fact Box

Dosage Forms Available	Tablet
Habit Forming	No
Ailment	Type 2 diabetes
Drug Category	Anti-diabetic
Therapeutic Category	Oral hypoglycemics

What does Loyzide M 80 Tablet Pr 15 contain?

Loyzide M 80 Tablet Pr 15 is a combination medicine that contains two medicines, i.e., gliclazide and metformin.

When should I take Loyzide M 80 Tablet Pr 15?

Loyzide M 80 Tablet Pr 15 should be taken with food each day. It should be taken at the same time every day to get the desired results. The dosage of the medicine is decided by the doctor, which may vary from time to time.

What is the action of Loyzide M 80 Tablet Pr 15?

The action of Loyzide M 80 Tablet Pr 15 is to lower the blood glucose levels in patients with diabetes.

Is Loyzide M 80 Tablet Pr 15 good for kidneys?

Loyzide M 80 Tablet Pr 15 should be used cautiously in patients suffering from kidney diseases. Dosage adjustment may be needed in patients with kidney diseases. Consult your doctor for advice.

Does Loyzide M 80 Tablet Pr 15 increase insulin?

Loyzide M 80 Tablet Pr 15 works by increasing insulin levels. The pancreas increases insulin production after taking Loyzide M 80 Tablet Pr 15.

Last Updated On 18 Nov. 2025 | 2:33PM (IST)

Certified Content

Written by

Dr. Nikhil Ambatkar

Medical Content Reviewer | 8 years

PhD (Biotechnology)

Reviewed by

Pragati Bhosale

Medical Content Reviewer | 4 years

M. Pharmacy

Check out Editorial Policy

Manufacturer details

702, Balaji Buisness Park, Andheri Kurla Road, Marol Naka, Andheri East, Mumbai, Maharashtra 400059

Country of origin: INDIA

Expiry on or after: August 2026

In case of any issues, contact us:

support@truemeds.in|09240250346

Address: 6th floor, Urmi Corporate Park Solaris, Saki Vihar Road, Andheri East, Mumbai 400071

References

GLIZID-M Gliclazide 80mg and Metformin 500mg.(n.d.). Hypoglycemic sulfonylurea - Oral Anti-diabetic Agent. Panaceabiotec.Com.(Retrieved August 2023). https://media.panaceabiotec.com/documents/2019/7/27/ProductMonograph-GlizidM-GliclazideplusMetformin.pdf
Gliclazide. (n.d.). (Retrieved August 2023). https://go.drugbank.com/drugs/DB01120
Metformin. (n.d.). Medlineplus.gov. (Retrieved August 2023). https://medlineplus.gov/druginfo/meds/a696005.html
Alsharidah, M., Algeffari, M., Abdel-Moneim, A.-M. H., Lutfi, M. F., & Alshelowi, H. (2018). Effect of combined gliclazide/metformin treatment on oxidative stress, lipid profile, and hepatorenal functions in type 2 diabetic patients. Saudi Pharmaceutical Journal: SPJ: The Official Publication of the Saudi Pharmaceutical Society, 26(1), 1–6. https://doi.org/10.1016/j.jsps.2017.11.007

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Disclaimer

We, at Truemeds make a diligent attempt to deliver accurate, expert- drafted and thoroughly reviewed medicine related information to our consumers. However, it should, by no means, be considered a substitute for prescription from a certified doctor or a trustworthy doctor-patient relationship. In fact we detest any form of self medication without expert advice. The sole purpose of the information on our portal is to educate our consumers, which helps improve the communication between a doctor and a patient. The information by no means is complete in its entirety and should not be used to diagnose or treat any medical condition. No amount of information can replace the experience and expertise of a doctor, therefore his/her advice always holds priority and should be followed appropriately.

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CIN: U62099MH2019PTC320566

Telephone:09240250346

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Name: Kishor Kumar

Email: grievance-officer@truemeds.in

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