Gufinox Injection 0.4ml is used to prevent and treat blood clots in conditions such as deep vein thrombosis (DVT) and pulmonary embolism (PE), and to help manage certain heart conditions such as unstable angina and some types of heart attack.
It contains enoxaparin, a low molecular weight heparin that reduces the blood's tendency to clot. It is given as an injection, with the dose determined by your doctor. If you are shown how to inject this medicine at home, follow the technique exactly and rotate the injection sites each time. Continue the treatment for the full duration prescribed, even if you feel well, to reduce the risk of clots forming or growing.
Avoiding activities with a high risk of injury or falls can help reduce the chance of bruising or bleeding while on this medicine. Staying mobile where possible, as advised by your doctor, can also help reduce clot risk.
Before starting this medicine, tell your doctor about any bleeding problems, recent surgery, stomach ulcers, or kidney or liver disease, and about other medicines you take, especially other blood thinners. Report unusual bruising, blood in the urine or stools, or prolonged bleeding promptly. This medicine should be used with caution during pregnancy.
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Gufinox Injection 0.4Ml
Pre-filled syringe of 0.40 ML
MRP ₹467.5
₹374
₹1168.75/ML
100% genuine medicines
Safe & secure payments
15 days Easy returns
Prescription required for this medicine
Store Below 30° C
CompositionAbout Gufinox Injection 0.4Ml
Uses of Gufinox Injection 0.4Ml
Gufinox Injection 0.4ml is used to prevent and treat blood clots in the legs and lungs, and to help manage certain heart conditions caused by reduced blood flow to the heart.
Uses of Gufinox Injection 0.4ml are:
- Deep Vein Thrombosis (DVT): Helps prevent and treat blood clots that form in the deep veins, usually in the legs.
- Pulmonary Embolism (PE): Helps manage blood clots that have travelled to the lungs.
- Heart Conditions: Used, often together with other medicines such as aspirin, to manage unstable angina and certain types of heart attack.
Directions for Use of Gufinox Injection 0.4Ml
- Gufinox Injection 0.4ml is administered by a healthcare professional.
- Ensure that the the site of injection area is clean and dry.
- This medicine is injected under the skin (subcutaneously) or into the veins (intravenously) as directed by your doctor.
Route of Administration
Gufinox Injection 0.4ml is administered subcutaneously or intravenously by a healthcare professional.
Side Effects of Gufinox Injection 0.4Ml
Gufinox Injection 0.4ml may cause some side effects during or after treatment; these are usually mild and managed by your care team.
A few common side effects of Gufinox Injection 0.4ml:
- Injection Site: Pain, bruising, or a small blood clot under the skin where the injection is given.
- Blood: A fall in platelet count (thrombocytopenia), which are needed for clotting.
- Liver: Raised liver enzymes, seen on blood tests, which can indicate strain on the liver.
If side effects do not improve or become serious, speak to your doctor or healthcare team right away.
Management Of Side Effects:
Most common side effects are temporary and generally harmless, which resolve on discontinuing the use of Gufinox Injection 0.4ml. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.
Here are some general suggestions for managing common side effects:
- Thrombocytopenia: If you notice unusual bruising or bleeding, try to avoid activities that could lead to injury.
- Local injection site reactions: Apply a clean, cool wet cloth to your skin at the injection site to help soothe any discomfort or swelling.
How Gufinox Injection 0.4Ml Works?
Gufinox Injection 0.4ml contains enoxaparin (40 mg), which works on your body in the following ways:
- Enhances Inhibition of Factor Xa and Thrombin: Enoxaparin boosts the inhibition of factor Xa and thrombin by antithrombin III. These factors are involved in blood coagulation, so inhibiting them helps prevent blood clots.
- Interrupts Blood Coagulation Cascade: By enhancing the inhibition of factor Xa and thrombin, enoxaparin interrupts the blood coagulation cascade, thus preventing the formation of blood clots.
Safety Measures & Warnings
Pregnancy
If you are pregnant, caution is advised while taking Gufinox Injection 0.4ml. Consult your doctor for appropriate advice.
Breastfeeding
Since it's uncertain if enoxaparin is excreted in human milk, it is essential to inform the doctor about the same before taking this injection.
Alcohol
Caution is advised when consuming alcohol if this injection is prescribed to you to avoid any adverse effects.
Liver
If you have liver health issues, it's advisable to consult your doctor before using Gufinox Injection 0.4ml. Your doctor will guide you based on your health status.
Kidney
In case of kidney health issues, particularly severe renal impairment, dosage adjustment may be necessary for Gufinox Injection 0.4ml. Consultation with your doctor prior to starting this medication is a good idea.
Use In Driving And Operating Machinery
Gufinox Injection 0.4ml's effect on the ability to drive or operate heavy machinery has not been studied. Nevertheless, it's crucial to be aware of how this medicine affects you before engaging in such activities.
Allergy
This medicine should not be used if you're allergic to enoxaparin, heparin, or pork products. If you have a history of allergies, make sure to discuss this with your doctor before starting Gufinox Injection 0.4ml.
Children
The safety and efficacy of Gufinox Injection 0.4ml in children have not been established. Always consult your doctor before giving any medicine to a child.
Older Patients
Older patients should take Gufinox Injection 0.4ml under medical supervision as they may be more susceptible to its side effects. Caution is advised for patients above 70 years of age who might also have liver and kidney issues. Your doctor will guide you based on your health status.
Interactions of Gufinox Injection 0.4Ml
Drug-Drug Interactions
Gufinox Injection 0.4ml interacts with the following medicines:
- Anticoagulants: Medicines such as warfarin can interact with Gufinox Injection 0.4ml and increase the risk of bleeding.
- Thrombolytic Agents: Medicines like alteplase can interact with Gufinox Injection 0.4ml, escalating the risk of bleeding.
- Non-Steroidal Anti-Inflammatory Medicines (NSAIDs): Medicines such as ibuprofen or naproxen may interact with Gufinox Injection 0.4ml, potentially heightening the risk of bleeding.
Drug-Food Interactions
Gufinox Injection 0.4ml does not have any known interactions with food.
Drug-Disease Interactions
Gufinox Injection 0.4ml interacts with the following diseases:
- Active Major Bleeding: Gufinox Injection 0.4ml can worsen this condition due to its anticoagulant effect.
- History of Heparin-induced Thrombocytopenia (HIT): This medicine should not be used if you have a history of HIT as it could lead to similar reactions.
Dosage of Gufinox Injection 0.4Ml
Daily Dose
The recommended dose for Gufinox Injection 0.4ml is decided by your healthcare professional. For further details regarding dosage instructions, please refer to the package insert.
Over Dose
Overdose of this injection is unlikely as it is administered by a healthcare professional.
Missed Dose
Gufinox Injection 0.4ml is administered subcutaneously or intravenously by a healthcare professional. In case a dose is missed, inform your doctor immediately.
Storage
- Store Gufinox Injection 0.4ml at room temperature, store below 25°C.
- Keep it away from direct light, heat, and moisture.
- Always place it in a secure place out of children's reach.
- Use the content within 28 days after the first use.
Special Dietary And Lifestyle Recommendation
- Eat a heart-friendly diet which includes foods low in saturated fats and high in fibre, such as fruits, vegetables, and whole grains. Also, try to limit your salt intake to manage blood pressure.
- Regular physical activity can help maintain healthy blood flow and reduce the risk of blood clots. Try to incorporate moderate exercise into your daily routine, but remember to consult your doctor about what's safe for you before starting any new exercise regimen.
Fact Box
| Dosage Forms Available | Injection |
| Habit Forming | No |
| Ailment | Deep Vein Thrombosis, Pulmonary Embolism, Unstable Angina |
| Drug Category | Anticoagulant |
| Therapeutic Category | Low Molecular Weight Heparin |
Frequently Asked Questions (FAQs)
What is Gufinox Injection 0.4ml used for?
Gufinox Injection 0.4ml is used to manage conditions involving the formation of blood clots, such as deep vein thrombosis and pulmonary embolism.
How does Gufinox Injection 0.4ml work?
It works by enhancing the inhibition of blood clotting factors, thus preventing the formation and spread of blood clots in your body.
Can I take Gufinox Injection 0.4ml if I am allergic to pork?
No, if you're allergic to pork, you should not take this medicine as it may cause hypersensitivity reactions.
Can I administer a Gufinox Injection 0.4ml if I have severe renal impairment?
You should consult your doctor before administering this medicine; adjustments may be necessary for patients with severe renal impairment.
What are the common side effects of Gufinox Injection 0.4ml?
Common side effects can include minor bleeding, reduced platelet count, increased liver enzymes, and discomfort at the injection site.
Can I use other anticoagulants or antiplatelet agents while administering Gufinox Injection 0.4ml?
Consult your doctor before using other anticoagulants or antiplatelet agents, as it may increase your risk of bleeding.
Is it safe to use Gufinox Injection 0.4ml during pregnancy or while breastfeeding?
Consult your doctor before administering this medicine if you are pregnant or breastfeeding. It should be used only if clearly needed.
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Manufacturer details
Country of origin: INDIA
References
- Research, C. F. D. E. A. (2018, February 6). Generic Enoxaparin questions and answers. U.S. Food And Drug Administration. https://www.fda.gov/drugs/postmarket-drug-safety-information-patients-and-providers/generic-enoxaparin-questions-and-answers
- Enoxaparin: Uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB01225
- Enoxaparin Injection: MedlinePlus Drug Information. (n.d.). https://medlineplus.gov/druginfo/meds/a601210.html
- Jupalli, A., & Iqbal, A. M. (2023, August 28). Enoxaparin. StatPearls - NCBI Bookshelf.https://www.ncbi.nlm.nih.gov/books/NBK539865/
Disclaimer
We, at Truemeds make a diligent attempt to deliver accurate, expert- drafted and thoroughly reviewed medicine related information to our consumers. However, it should, by no means, be considered a substitute for prescription from a certified doctor or a trustworthy doctor-patient relationship. In fact we detest any form of self medication without expert advice. The sole purpose of the information on our portal is to educate our consumers, which helps improve the communication between a doctor and a patient. The information by no means is complete in its entirety and should not be used to diagnose or treat any medical condition. No amount of information can replace the experience and expertise of a doctor, therefore his/her advice always holds priority and should be followed appropriately.
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