Gride M Tablet 10

East West Pharma

Strip of 10 Units

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Old MRP ₹76.84

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₹57.63

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Prescription required for this medicine

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Composition

Glimepiride (1 Mg) + Metformin (500 Mg)

Gride-M Tablet is primarily used to manage type 2 diabetes mellitus. This combination medicine is part of the antidiabetic class of medications, designed to regulate blood sugar levels.

This medicine is also beneficial when diet and exercise alone cannot effectively control your blood sugar levels. If you've tried single-agent therapy and it's not giving you the results you need, your doctor might recommend this medication to help manage your blood sugar levels more effectively.

Before starting on this medicine, it's important to discuss your medical history and any current medications with your doctor. If you experience any side effects while taking this medicine, make sure to inform your doctor right away. It's also essential to continue taking the medicine for the entire duration prescribed by your doctor to see the best results.

Gride-M Tablet is used for the following:

Management of type 2 diabetes mellitus.
Regulation of blood sugar levels when diet and exercise are not sufficient.
Control of high blood sugar when single-agent therapy with either Glimepiride or Metformin is inadequate.
Maintenance of blood glucose levels in adults diagnosed with type 2 diabetes.

Follow these instructions while taking Gride-M Tablet:

Swallow the tablet whole with a glass of water.
Do not crush or chew the tablet.
It's important not to stop taking this medicine without speaking to your doctor first.
Regular monitoring of your blood sugar levels is essential. Consult your doctor for specific advice on how frequently you need to measure your glucose levels.

Gride-M Tablet is taken orally.

The following common side effects may occur with Gride-M Tablet:

Hypoglycaemia: This refers to low blood sugar, which can make you feel weak and dizzy.
Nausea
Vomiting
Diarrhoea
Stomach discomfort: This might be a feeling of fullness or bloating in your stomach.
Headache
Dizziness
Weakness or fatigue

Management Of Side Effects:

Most side effects are temporary and generally harmless, which resolve on discontinuing the use of Gride-M Tablet. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

To manage common side effects:

Hypoglycaemia: If you experience low blood sugar, consider having a small snack before taking the medicine.
Stomach discomfort: Taking Gride-M Tablet with meals may help reduce feelings of fullness or bloating.

Gride-M Tablet consists of two active ingredients that work together to regulate your blood sugar levels:

Glimepiride (1 mg): As a sulfonylurea class of antidiabetic medicine, glimepiride helps control your blood sugar levels by encouraging your pancreas to release more insulin. This process aids in transferring sugar from your bloodstream into your cells, where it's used for energy.
Metformin (500 mg): A member of the biguanide class of antidiabetic medicines, metformin reduces the amount of glucose your intestines absorb from food. It also decreases glucose production in your liver. Furthermore, metformin improves your body's sensitivity to insulin, which allows your cells to utilise blood glucose more efficiently.

Pregnancy

Gride-M Tablet should not be used during pregnancy unless the potential benefit justifies the potential risk to the unborn baby. Please consult your doctor before taking this medicine if you are pregnant or planning to conceive.

Breastfeeding

Gride-M Tablet is excreted into human milk. It is best to discuss with your doctor whether to stop nursing or discontinue the medicine, considering its importance to you.

Alcohol

You should avoid excessive alcohol consumption while taking Gride-M Tablet, as it may increase the risk of lactic acidosis and hypoglycaemia.

Liver

If you have liver problems, caution is advised before starting Gride-M Tablet. This medicine could affect liver function, so it's recommended to consult with your doctor before use.

Kidney

Gride-M Tablet is contraindicated in patients with severe kidney impairment. If you have a history of kidney problems, it's important to consult your doctor before taking this medicine.

Use In Driving And Operating Machinery

Gride-M Tablet may cause low blood sugar levels that could lead to dizziness or fainting. This can affect your ability to drive or operate machinery. Be cautious and discuss this with your doctor.

Allergy

If you're allergic to Glimepiride, Metformin, or any other component of Gride-M Tablet, do not take this medicine. Remember to inform your doctor about any known allergies

Children

Gride-M Tablet is not recommended for children under 18 years of age. A doctor should be consulted before giving this medicine to a child.

Older Patients

Older patients should take Gride-M Tablet under medical supervision as they may be more susceptible to its side effects. Caution is advised if patients are above 70 years of age. Your doctor will guide you based on your health status.

Drug-Drug Interactions

Gride-M Tablet interacts with the following medicines:

Beta-blockers: Medicines like propranolol or atenolol might increase the blood sugar-lowering action of Glimepiride, a component of Gride-M Tablet.
Salicylates: Medicines such as aspirin can potentiate the hypoglycemic effect of Glimepiride.
Monoamine oxidase inhibitors (MAOIs): Medicines like phenelzine or selegiline may enhance the blood sugar-reducing effect of Glimepiride.
Thiazides: Medicines such as hydrochlorothiazide might increase blood sugar levels, reducing the effectiveness of Gride-M Tablet.
Corticosteroids: Medications like prednisone can cause hyperglycemia, which could counteract the effect of Gride-M Tablet.
Cationic medicines: Amiloride, digoxin, morphine and others can interact with Metformin, a component of Gride-M Tablet, increasing the risk for lactic acidosis.

Drug-Food Interactions

Gride-M Tablet interacts with certain foods.

High-fat meals: These could slow down the absorption of Glimepiride and Metformin from your gut, potentially reducing their effectiveness.

Drug-Disease Interactions

Gride-M Tablet interacts with the following diseases:

Kidney disease: People with kidney problems might have increased risks when taking Gride-M Tablet due to potential accumulation and increased side effects.
Liver disease: Liver issues can affect how your body processes Glimepiride and Metformin in Gride-M Tablet, possibly leading to increased side effects.
Heart problems: Patients with heart conditions need to be cautious when using Gride-M Tablet due to a potential increase in cardiovascular mortality with Glimepiride.
Glucose-6-phosphate dehydrogenase (G6PD) deficiency: This condition may lead to hemolytic anaemia with Glimepiride use.

Daily Dose

Take the daily recommended dose of Gride-M Tablet as prescribed by your doctor. Your dosage may be adjusted depending on factors such as your response to treatment and the severity of your condition. Always follow the prescribed dosage and avoid exceeding it without consulting your doctor.

Over Dose

If you accidentally take more than the prescribed dose of Gride-M Tablet, you might experience common side effects like fatigue, nausea, or a headache. In case of an overdose, get in touch with your doctor right away.

Missed Dose

In case you miss a dose of Gride-M Tablet, take it as soon as you remember. If it's almost time for your next dose, skip the missed one and continue with your regular dosing schedule. Do not take extra medicine to make up for a missed dose without consulting your doctor.

Keep Gride-M Tablet at room temperature.
Ensure the medicine stays in its original packaging to protect from humidity.
Put it in a place where children cannot reach.
Always check the expiry date on the package before taking Gride-M Tablet.

Maintain a balanced diet with a focus on whole grains, fruits, vegetables, and lean proteins. This helps manage blood sugar levels and supports overall health when taking Gride-M Tablet for type 2 diabetes.
Incorporate regular physical activity into your routine. Exercise can enhance insulin sensitivity and help keep your blood glucose levels in check. However, always consult your doctor before starting any new workout regimen.

Fact Box

Dosage Forms Available	Tablet
Habit Forming	No
Ailment	Type 2 Diabetes Mellitus
Drug Category	Sulfonylurea, Biguanide
Therapeutic Category	Antidiabetic

What is Gride-M Tablet used for?

Gride-M Tablet is used to manage type 2 diabetes when diet, exercise, and single-agent therapy aren't effective in controlling blood sugar levels.

How does Gride-M Tablet work?

Gride-M Tablet contains glimepiride and metformin, which work together to control blood sugar. Glimepiride stimulates insulin release, while metformin reduces glucose absorption.

Can I take other diabetes medicines with Gride-M Tablet?

Yes, you can use Gride-M Tablet with other diabetes medicines like insulin, under a doctor's guidance to prevent low blood sugar.

What happens if I miss a dose?

If you miss a dose of Gride-M Tablet, take it as soon as you remember. If it's nearly time for the next dose, skip the missed one.

Can I consume alcohol while on Gride-M Tablet?

Excessive alcohol consumption should be avoided while taking Gride-M Tablet as it can increase the risk of lactic acidosis and hypoglycemia.

How often should I check my blood sugar levels while on this medicine?

The frequency of blood sugar monitoring will depend on individual needs and treatment goals. Consult your doctor for specific recommendations.

Is Gride-M Tablet safe during pregnancy or breastfeeding?

Using Gride-M Tablet during pregnancy or breastfeeding should be discussed with your doctor since the benefits must outweigh potential risks.

Last Updated On 13 May. 2025 | 10:31AM (IST)

Certified Content

Written by

Dr Nikita Lobo

Medical Content Reviewer | 9 years

BDS, MDS

Reviewed by

Dr. Chhavi Rosha

Medical Content Writer | 10 years

BAMS, FMC, MD Resident

Check out Editorial Policy

Manufacturer details

1(1) ERRABALU (CHETTY STREET) MANNADY, VOC NAGAR CHENNAI Chennai - 600001 Tamil Nadu - India

Country of origin: INDIA

Expiry on or after: January 2027

In case of any issues, contact us:

support@truemeds.in|09240250346

Address: 6th floor, Urmi Corporate Park Solaris, Saki Vihar Road, Andheri East, Mumbai 400071

References

Unknown. (n.d.). Metformin hydrochloride Prolonged Release & Glimepiride tablets I.P. [Pharmaceutical Information]. https://www.sanofi.in/dam/jcr:6c1f15ea-d4af-4e93-b38c-91a76293b247/Amaryl%20M%20-%20PI.pdf
Unknown. (2022). GLUCOPHAGE. https://www.accessdata.fda.gov/drugsatfda_docs/label/2017/020357s037s039,021202s021s023lbl.pdf
AMARYL. (n.d.). AMARYL (glimepiride tablets) 1, 2, and 4 mg. https://www.accessdata.fda.gov/drugsatfda_docs/label/2009/020496s021lbl.pdf
Metformin: Uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB00331
Glimepiride: Uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB00222

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Disclaimer

We, at Truemeds make a diligent attempt to deliver accurate, expert- drafted and thoroughly reviewed medicine related information to our consumers. However, it should, by no means, be considered a substitute for prescription from a certified doctor or a trustworthy doctor-patient relationship. In fact we detest any form of self medication without expert advice. The sole purpose of the information on our portal is to educate our consumers, which helps improve the communication between a doctor and a patient. The information by no means is complete in its entirety and should not be used to diagnose or treat any medical condition. No amount of information can replace the experience and expertise of a doctor, therefore his/her advice always holds priority and should be followed appropriately.

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Intellihealth Solutions Private Limited

Unit-301 & 304, Lightbridge Tunga Village, Saki Vihar Rd, Chandivali, Powai, Mumbai, Maharashtra, India, 400072.

CIN: U62099MH2019PTC320566

Telephone:09240250346

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Name: Kishor Kumar

Email: grievance-officer@truemeds.in

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