Gliclize M 40 Tablet - Uses, Side Effects, Dosage, Price

About Gliclize M 40 Tablet 10

Gliclize M 40 Tablet 10 is used to manage type 2 diabetes in adults when a single medicine, diet and exercise are not enough. It is a combination medicine containing gliclazide (a sulfonylurea) and metformin (a biguanide).

It controls blood sugar and helps reduce the long-term risk of complications. Take it with food, in the dose, frequency and duration prescribed by your doctor, and do not skip meals, as this can cause low blood sugar. Carry a source of sugar with you.

Eat regular meals with controlled portions of rice, roti and sweets, and stay physically active.

Before starting, tell your doctor if you have kidney or liver problems, and about all other medicines, supplements or herbal products you take. Seek urgent help for severe weakness or breathlessness, which can rarely signal lactic acidosis. Follow the prescribed dose, frequency and duration, report persistent or serious side effects, and do not stop the medicine unless your doctor advises you to do so.

Frequently Asked Questions (FAQs)

What is the purpose of Gliclize M 40 Tablet 10?

Gliclize M 40 Tablet 10 is used to manage type 2 diabetes, alongside a healthy diet and regular exercise, by controlling high blood sugar levels.

How does Gliclize M 40 Tablet 10 work?

The medicine has gliclazide and metformin that reduce blood glucose levels. Gliclazide stimulates insulin secretion while metformin decreases hepatic glucose creation and boosts insulin sensitivity.

Can I take Gliclize M 40 Tablet 10 if I am allergic to its ingredients?

No, if you are allergic to gliclazide or metformin, you should not take this medicine. Consult your doctor for alternative medications.

Is it safe to consume alcohol while taking Gliclize M 40 Tablet 10?

Alcohol can increase the risk of lactic acidosis with metformin and boost the hypoglycaemic effect of gliclazide. Therefore, avoid consuming alcohol while taking this medicine.

Can Gliclize M 40 Tablet 10 cause hypoglycaemia?

Yes, gliclazide in Gliclize M 40 Tablet 10 can lead to hypoglycaemia (low blood sugar), particularly if meals are missed or delayed or when other antidiabetic medicines are added.

What happens if I overdose on Gliclize M 40 Tablet 10?

Overdose may lead to serious conditions like lactic acidosis and prolonged low blood sugar. If you suspect an overdose, seek immediate medical attention.

Is it okay to stop Gliclize M 40 Tablet 10 abruptly?

No, discontinuing any antidiabetic medication suddenly might lead to uncontrolled blood sugar levels which can be dangerous. Always consult your doctor before making any changes.

References

Panacea Biotec Limited. (2019). PRODUCT MONOGRAPH GLIZID-M gliclazide 80mg and Metformin 500mg. https://media.panaceabiotec.com/documents/2019/7/27/ProductMonograph-GlizidM-GliclazideplusMetformin.pdf
Gliclazide: Uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB01120
Metformin: Uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB00331
Polavarapu, N. K., Kale, R., Sethi, B., Sahay, R. K., Phadke, U., Ramakrishnan, S., Mane, A., Mehta, S., & Shah, S. (2020). Effect of Gliclazide or Gliclazide plus Metformin Combination on Glycemic Control in Patients with T2DM in India: A Real-World, Retrospective, Longitudinal, Observational Study from Electronic Medical Records. Drugs - Real World Outcomes, 7(4), 271–279. https://doi.org/10.1007/s40801-020-00206-7
Alsharidah, M., Algeffari, M., Abdel-Moneim, A. H., Lutfi, M. F., & Alshelowi, H. (2018). Effect of combined gliclazide/metformin treatment on oxidative stress, lipid profile, and hepatorenal functions in type 2 diabetic patients. Saudi Pharmaceutical Journal, 26(1), 1–6. https://doi.org/10.1016/j.jsps.2017.11.007

Disclaimer

We, at Truemeds make a diligent attempt to deliver accurate, expert- drafted and thoroughly reviewed medicine related information to our consumers. However, it should, by no means, be considered a substitute for prescription from a certified doctor or a trustworthy doctor-patient relationship. In fact we detest any form of self medication without expert advice. The sole purpose of the information on our portal is to educate our consumers, which helps improve the communication between a doctor and a patient. The information by no means is complete in its entirety and should not be used to diagnose or treat any medical condition. No amount of information can replace the experience and expertise of a doctor, therefore his/her advice always holds priority and should be followed appropriately.