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CompositionColihenz P 400 Tablet is a combination medicine used to manage cognitive impairments such as memory loss, Alzheimer's disease, and recovery after stroke or brain injury. It falls under the category of nootropic medicines (containing Citicoline and Piracetam). These components work together to protect nerve cells, enhance brain function, support blood flow, and improve cognitive functions like memory and attention.
Colihenz P 400 Tablet is prescribed to treat cognitive problems caused by stroke or brain injury. It contains Citicoline and Piracetam, which help protect brain cells, improve memory, and support recovery during rehabilitation to enhance brain function and mental alertness.
Swallow the tablet whole with a glass of water.
Avoid crushing or chewing the tablet.
The medicine can be taken with or without food.
Consistency is key, try to take it at the same time each day for best results.
Don't take more than the recommended dose without consulting your doctor.
Colihenz P400 Tablet is taken orally.
Colihenz P 400 Tablet may cause stomach pain, diarrhea, uncoordinated body movements, hyperactivity, nervousness, dizziness, decreased blood pressure, and weight gain.
Stomach pain: Taking Colihenz P400 Tablet with meals could help manage this side effect.
Dizziness: Try taking this medicine at bedtime if it makes you feel dizzy during the day.
Colihenz P400 tablet consists of the following two components:
Citicoline (500 mg): This substance plays a vital role in the formation of phosphatidylcholine, a key component of cell membranes. It boosts levels of neurotransmitters such as acetylcholine, dopamine, and noradrenaline that facilitate brain communication. Citicoline also exhibits neuroprotective properties – it helps repair damaged brain cells and enhances blood circulation within the brain.
Piracetam (400 mg): A member of the racetam family of nootropics, piracetam works by enhancing neuroplasticity and increasing energy reserves in the brain. It improves the fluidity of cell membranes thereby facilitating information transfer within the brain cells. Moreover, piracetam has anticonvulsant and neuroprotective effects which contribute to overall brain health.
This medicine is contraindicated during pregnancy. If you are pregnant or planning to conceive, you should discuss this with your doctor before starting on Colihenz P400 Tablet.
Colihenz P400 Tablet is contraindicated for breastfeeding women. You should consult your doctor to understand the potential risks and benefits.
It's always wise to consult your doctor before taking this medicine if you consume alcohol regularly.
Caution is advised while taking Colihenz P400 Tablet in case of mild to moderate liver impairment. This medicine may affect liver function. Discuss your liver health with your doctor before starting this medication.
If you have a history of kidney problems, caution is advised before using Colihenz P400 Tablet. It's a good idea to consult your doctor before taking this medicine.
Colihenz P400 Tablet may cause dizziness. Therefore, caution is recommended when driving or operating machinery until you know how this medicine affects you.
This medicine is contraindicated if you have known hypersensitivity to citicoline, piracetam or any other components of Colihenz P400 Tablet.
Caution is advised while giving Colihenz P400 Tablet to individuals under 18 years of age. Always consult a doctor before giving any medicine to a child.
Older patients should take Colihenz P400 Tablet under medical supervision as they may be more susceptible to its side effects. Your doctor will guide you based on your health status if you are above 70 years of age.
Levodopa: Citicoline in the medicine may have additive effects when used along with levodopa, often used for Parkinson's disease.
Anticoagulants and Antiplatelets: Piracetam in Colihenz P400 Tablet may potentiate the effects of medicines like warfarin and clopidogrel, increasing the risk of bleeding.
Thyroid hormones: Piracetam may enhance the effects of medicines like levothyroxine and thyroxine.
Oxiracetam: Concomitant use with this nootropic could potentially intensify side effects.
There are no specific known food interactions with Colihenz P400 Tablet.
Renal impairment: Patients with severe renal problems should exercise caution while taking this medicine as dose adjustment may be required.
Huntington's disease: Piracetam present in this medicine may potentially aggravate symptoms in patients suffering from Huntington's disease.
The daily dose of Colihenz P400 Tablet should be as advised by your doctor. The prescribed dosage can vary based on factors such as the severity of your condition and how you respond to the medication. It's essential that you stick to the recommended dosage and don't exceed it without consulting your doctor.
In case of an overdose of Colihenz P400 Tablet, you may experience symptoms such as agitation, confusion, tremors, drowsiness and in severe cases, even coma. If you suspect an overdose, it's important to get medical attention promptly.
If you forget to take a dose of Colihenz P400 Tablet, take it as soon as you remember. However, if it's close to the time for your next dose, skip the missed dose and continue with your regular dosage schedule. You should never increase your dosage without consulting your doctor.
Store Colihenz P400 Tablet in a cool, dry place, ideally at a temperature below 30 degrees Celsius.
Avoid exposure to direct sunlight and excessive moisture.
Keep it out of reach of children to prevent accidental ingestion.
Make sure you use the medication before its expiry date.
Engage in cognitive exercises like puzzles, reading, or memory games, as this medicine is used to manage cognitive decline and memory impairment.
Consume a diet rich in omega-3 fatty acids (like fish and nuts) which can support brain health.
| Available Dosage Types | Tablet |
| Habit Forming | No |
| Ailment | Stroke recovery, Dementia, Parkinson's disease |
| Drug Category | Cognitive Function Enhancer |
| Therapeutic Category | Nootropic |
Colihenz P400 Tablet is used to manage cognitive impairments such as memory loss, Alzheimer's disease, stroke recovery, and Parkinson's disease among others.
The medicine contains citicoline and piracetam. They work together to increase neurotransmitter levels, improve brain cell health, and enhance information transfer for better brain function.
Yes, you can take this medicine with or without food. However, it is advisable to take it at the same time each day for best results.
If you miss a dose, take it as soon as you remember. However, if it's nearly time for the next dose, skip the missed one. Never double up on doses.
Possible side effects include stomach pain, diarrhoea, dizziness, nervousness and weight gain among others. Consult your doctor if these persist or worsen.
This medicine is contraindicated during pregnancy. If you are pregnant or planning to conceive, you should discuss this with your doctor before starting on Colihenz P400 Tablet.
It's best to avoid alcohol while using this medication as it may intensify side effects like drowsiness and dizziness. Always consult your doctor for advice.
Check out Editorial Policy
U.S. Food and Drug Administration. (2012). Nootropil (piracetam) Tablets: U.S. Prescribing Information. Retrieved from https://www.accessdata.fda.gov/drugsatfda_docs/label/2012/203155s000lbl.pdf
U.S. Food and Drug Administration. (2015). CerAxon (citicoline) Oral Solution: U.S. Prescribing Information. Retrieved from https://www.accessdata.fda.gov/drugsatfda_docs/label/2015/019651s025lbl.pdf
Zhang, Y., Dai, Y., & Zhang, Y. (2020). Efficacy of Citicoline for the Treatment of Acute Ischemic Stroke: A Meta-Analysis. Neuropsychiatric Disease and Treatment, 16, 2383–2391. Retrieved from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7601330/
Shao, Y., Le, W., & Zhang, Y. (2019). Citicoline (CDP-choline) for cognitive and behavioural disturbances associated with chronic cerebral disorders in the elderly. Cochrane Database of Systematic Reviews, (4). Retrieved from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6741724/
Citicoline: Uses, Interactions, Mechanism of Action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB12153
PubChem. (n.d.-q). Citicoline. PubChem. https://pubchem.ncbi.nlm.nih.gov/compound/citicoline
We, at Truemeds make a diligent attempt to deliver accurate, expert- drafted and thoroughly reviewed medicine related information to our consumers. However, it should, by no means, be considered a substitute for prescription from a certified doctor or a trustworthy doctor-patient relationship. In fact we detest any form of self medication without expert advice. The sole purpose of the information on our portal is to educate our consumers, which helps improve the communication between a doctor and a patient. The information by no means is complete in its entirety and should not be used to diagnose or treat any medical condition. No amount of information can replace the experience and expertise of a doctor, therefore his/her advice always holds priority and should be followed appropriately.
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