Toplep 25 MG Tablet 10

Tripada Healthcare Pvt Ltd

Pack of 10 Units

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MRP ~~₹38~~

₹30.4

₹3.8/Units

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Composition

Topiramate (25 Mg)

Toplep 25 MG Tablet 10 is primarily used for managing migraine headaches in adults. This medicine is part of the antiepileptic class of medications known as anticonvulsants.

This tablet can also be used in the management of epilepsy and seizures. It helps control the electrical activity in the brain, thus managing seizures and relieving migraine symptoms.

You must take this medicine as directed by your doctor. Before starting this medication, let your doctor know about any health conditions you may have or any other medicines you are currently taking. If you notice any severe side effects while on this medicine, notify your doctor immediately. For optimal results, continue taking this medication for the duration as recommended by your doctor.

Toplep 25 MG Tablet 10 has several uses, including the following:

Migraine headaches in adults
Epilepsy
Lennox-Gastaut syndrome

Swallow the tablet whole with a glass of water.
Try to take the medicine at the same time each day, with or without food.
Avoid crushing or chewing the tablet.
Do not exceed the recommended dose without consulting your doctor.
Consult your doctor before stopping the medication, as it may increase seizure frequency.

Toplep 25 MG Tablet 10 is taken orally.

Toplep 25 MG Tablet 10 may have the following common side effects:

Abdominal pain
Diarrhoea
Dizziness
Fatigue
Fever
Loss of appetite
Memory impairment: This could mean difficulty remembering or learning new things.
Nausea
Nervousness
Numbness: You might feel a lack of sensation in some parts of your body.
Psychomotor impairment: This refers to trouble with physical activities and actions that require hand-eye coordination.
Sleepiness

Managing the Side Effects:

Most side effects are temporary and generally harmless, which resolve upon discontinuing the use of Toplep 25 MG Tablet 10. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

Here are some general guidelines for managing common side effects:

Abdominal pain: Try taking Toplep 25 MG Tablet 10 with food to lessen this effect.
Sleepiness: Consider taking this medicine at night if it causes drowsiness during the day.

Toplep 25 MG Tablet 10 contains topiramate (25 mg) as its active ingredient. The medicinal activity of topiramate is outlined below:

Neuronal Activity Regulation: Topiramate restores balance in the brain's neural activity. By controlling electrical impulses in the brain, it helps manage seizures and migraines.
Modulation of Neurotransmitters and Ion Channels: Topiramate works by affecting various neurotransmitters and ion channels. This action helps limit the spread of seizure activity in the brain.

Pregnancy

Toplep 25 MG Tablet 10 may increase the risk of cleft lip and cleft palate in infants while taking the medicine during pregnancy. It is best to consult your doctor before taking this medicine.

Breastfeeding

Caution is advised while taking Toplep 25 MG Tablet 10 if you are breastfeeding. It's essential to discuss this with your doctor.

Alcohol

While using Toplep 25 MG Tablet 10, it's best to limit or avoid alcohol intake as it may worsen the side effects like dizziness and sleepiness.

Liver

Toplep 25 MG Tablet 10 should be used with care in patients with liver disease. If you have liver health issues, consult your doctor before starting this medicine.

Kidney

If you have any kidney problems, caution is recommended before starting Toplep 25 MG Tablet 10. It's a good idea to discuss kidney-related concerns with your doctor before beginning treatment.

Using Machines & Driving

Toplep 25 MG Tablet 10 may cause dizziness, visual impairment, and psychomotor impairment, which could affect your ability to drive or operate machinery. Be aware of how this medicine affects you before driving or using machines.

Allergy

If you're allergic to topiramate or any other ingredients in Toplep 25 MG Tablet 10, avoid taking this medicine. Always inform your doctor about any allergies you have.

Children

Toplep 25 MG Tablet 10 is meant for adults. Always consult a doctor before giving any medicine to a child.

Older Patients

Older patients should use Toplep 25 MG Tablet 10 under medical supervision, as they may be more susceptible to its side effects. If you are over 70 years of age or have liver and kidney issues, consult your doctor for guidance.

Drug-Drug Interactions

Toplep 25 MG Tablet 10 can interact with the following medications:

Valproic Acid: Toplep 25 MG Tablet 10 may increase the blood levels of valproic acid, potentially enhancing side effects.
Oral Contraceptives: Toplep 25 MG Tablet 10 might reduce the effectiveness of oral contraceptives like levonorgestrel and ethinylestradiol, potentially increasing the chance of pregnancy.
Anti-Epileptic Medications: When taken with other anti-epileptics such as phenytoin and carbamazepine, Toplep 25 MG Tablet 10 may affect their blood concentration levels, influencing their efficacy.
Anti-Diabetic Medications: Concurrent use of metformin and Toplep 25 MG Tablet 10 can lead to alterations in blood sugar control.

Drug-Food Interactions

Toplep 25 MG Tablet 10 has no known interactions with food.

Drug-Disease Interactions

Toplep 25 MG Tablet 10 can interact with the following diseases:

Kidney Disease: Patients with kidney disease may need dosage adjustments for Toplep 25 MG Tablet 10 due to decreased drug clearance.
Liver Disease: Toplep 25 MG Tablet 10 should be used cautiously in individuals with liver disease because it is metabolized by the liver.
Metabolic Acidosis: People with metabolic acidosis should use this medicine carefully as it can lead to a further decrease in serum bicarbonate levels.
Glaucoma: The medication might increase intraocular pressure, worsening glaucoma.

Daily Dose

Take the daily recommended dose of Toplep 25 MG Tablet 10 as guided by your doctor. Your dosage might be adjusted based on factors like the severity of your condition and how you respond to the medicine. Always follow the prescribed dosage and never exceed it without consulting your doctor.

Over Dose

If you accidentally take more than the recommended dose of Toplep 25 MG Tablet 10, you might experience symptoms like dizziness, fatigue, and sleepiness. If these symptoms persist or get worse, inform your doctor without delay.

Missed Dose

If you forget to take your Toplep 25 MG Tablet 10, take it as soon as you remember. However, if it's nearly time for your next dose, miss out on the forgotten one now and return to your regular dosing schedule. Never alter your dosage without first consulting your doctor.

Store Toplep 25 MG Tablet 10 at room temperature, ideally below 30°C.
Shield the medicine from direct sunlight and moisture to maintain its effectiveness.
Keep this medication in its original packaging until it's time to take it.
Place the medicine out of reach of children to prevent accidental ingestion.
Always check the expiry date before taking the medicine.

Regularly practice relaxation techniques such as meditation or deep-breathing exercises. These can help manage stress, which can trigger migraines and seizures.
Stay well-hydrated throughout the day. Drinking plenty of water helps prevent kidney stones, a potential side effect of topiramate.

Fact Box

Available Dosage Types	Tablet
Habit Forming	No
Ailment	Migraine prevention, Epilepsy
Drug Category	Anticonvulsant
Therapeutic Category	Antiepileptic

What is Toplep 25 MG Tablet 10 used for?

It's primarily used to manage epilepsy and seizures and to prevent migraines in adults.

How does Toplep 25 MG Tablet 10 work?

The active ingredient, topiramate, helps restore the balance of neural activity in the brain, controlling seizures and preventing migraines.

Does the Toplep 25 MG Tablet 10 help with anxiety?

It is not recommended to use Toplep 25 MG Tablet 10 to treat anxiety. Before taking the medication, please consult your doctor.

I've been taking Toplep 25 MG Tablet 10 for a long time; is it okay to continue taking them for a longer period of time?

Yes, using a Toplep 25 MG Tablet 10 for an extended period of time is safe, if a doctor recommends it.

Are there any precautions to consider while taking Toplep 25 MG Tablet 10?

Use with caution if you have kidney disease, liver disease, lung disease, breathing problems, metabolic acidosis, or glaucoma.

Can Toplep 25 MG Tablet 10 interact with other medications?

Yes, it may interact with medications such as valproic acid, oral contraceptives, phenytoin, carbamazepine and metformin.

Can my fertility get affected by Toplep 25 MG Tablet 10?

No, the Toplep 25 MG Tablet 10 has no effect on conception.

Last Updated On 13 May. 2025 | 11:19AM (IST)

Certified Content

Written by

Dr. Michelle Frank

Medical Content Writer | 9 years

Doctor of Medicine

Reviewed by

Dr. Saniya K Mulla

Medical Content Writer | 6 years

MBBS

Check out Editorial Policy

Manufacturer details

1 Yogi Complex, Near Dordarshan Kendra Drive In Road, Drive In Ahmedabad, 380054

Country of origin: INDIA

Expiry on or after: October 2025

In case of any issues, contact us:

support@truemeds.in|08069808861

Address: 6th floor, Urmi Corporate Park Solaris, Saki Vihar Road, Andheri East, Mumbai 400071

References

MedlinePlus. (2022). Topiramate. Retrieved 1 April 2024, from https://medlineplus.gov/druginfo/meds/a697012.html
Minton, G. C., Miller, A. D., Bookstaver, P. B., & Love, B. L. (2011). Topiramate: Safety and efficacy of its use in the prevention and treatment of migraine. Journal of Central Nervous System Disease, 3, JCNSD.S4365. https://doi.org/10.4137/jcnsd.s4365
U.S. Food and Drug Administration. (2022). NDA 20-505/S-064 NDA 20-844/S-054. Retrieved 1 April 2024, from https://www.accessdata.fda.gov/drugsatfda_docs/label/2022/020505s064,020844s054lbl.pdf
Liu, Y.-T., Chen, G.-T., Huang, Y.-C., Ho, J.-T., Lee, C.-C., Tsai, C.-C., & Chang, C.-N. (2020). Effectiveness of dose-escalated topiramate monotherapy and add-on therapy in neurosurgery-related epilepsy: A prospective study. Medicine, 99(52), e23771. https://doi.org/10.1097/md.0000000000023771

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Disclaimer

We, at Truemeds make a diligent attempt to deliver accurate, expert- drafted and thoroughly reviewed medicine related information to our consumers. However, it should, by no means, be considered a substitute for prescription from a certified doctor or a trustworthy doctor-patient relationship. In fact we detest any form of self medication without expert advice. The sole purpose of the information on our portal is to educate our consumers, which helps improve the communication between a doctor and a patient. The information by no means is complete in its entirety and should not be used to diagnose or treat any medical condition. No amount of information can replace the experience and expertise of a doctor, therefore his/her advice always holds priority and should be followed appropriately.

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