Testenate Depot 250 Injection 1ml

Searle (india) Limited

Ampoule of 1 ML

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MRP ~~₹196.88~~

₹98.24

₹196.88/ML

50.1% off

*MRP inclusive of all taxes

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Prescription required for this medicine

Store Below 30^o C

Composition

Benzyl Alcohol (2 %) + Testosterone (250 Mg)

Testenate Depot-250 Injection is primarily used to manage conditions related to a deficiency or absence of the male sex hormone, testosterone. It belongs to a class of medicines known as androgen medications.

Besides its main use, this injection also helps manage various symptoms that arise due to low testosterone levels, including delayed puberty, impotence, infertility, low libido, persistent fatigue and weakness, and osteoporosis. Additionally, it can serve as supportive therapy for female-to-male transgender individuals.

Before starting this injection, it's crucial to consult your doctor who will guide you on the correct dosage and frequency. You should tell your doctor about any pre-existing conditions or other ongoing medications. If you notice any side effects while on this medicine, inform your doctor immediately. It's important to continue with the injection for the duration prescribed by your doctor for the best results.

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Testenate Depot-250 Injection is used for the following:

Replacement of testosterone in cases of male hypogonadism
Managing delayed puberty in males
Addressing impotence and infertility caused by hormonal deficiency
Tackling low libido problems
Countering fatigue and weakness due to testosterone deficiency
Managing osteoporosis in men with low testosterone levels
Supporting hormone replacement therapy in female-to-male transgender individuals

Here's how you administer Testenate Depot-250 Injection:

The injection is administered deeply into a muscle, usually the gluteal muscle.
This medicine should only be administered by or under the supervision of a doctor.
For each administration, ensure that the injection site is clean to avoid infection.
Remember to consult your doctor for specific instructions and advice.

Testenate Depot-250 Injection is administered via an intramuscular route.

Testenate Depot-250 Injection may cause the following common side effects:

Acne
Pain and redness at the injection site
Hair loss
Headache
Dizziness
Mood changes
Weight gain
Abnormal liver function tests: These tests measure how well your liver is working, and this medicine could cause these results to change.
Swelling or edema: This is water retention in certain parts of your body.
Sleep apnea: This is a condition where you stop breathing briefly while you're asleep.

Managing the Side Effects:

Most side effects are temporary and generally harmless, which resolve upon discontinuing the use of Testenate Depot-250 Injection. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

Here are some general guidelines for managing common side effects:

Pain and redness at the injection site: You may consider applying a cold compress to the area after the injection is administered to help reduce pain and inflammation.
Sleep apnea: Try adjusting your sleeping position or avoid administering this medicine close to bedtime.

Testenate Depot-250 Injection contains two active ingredients:

Testosterone (250 mg): As an endogenous androgen, testosterone plays a major role in the normal growth and development of male sex organs and maintenance of secondary sex characteristics. Its functions include stimulating the growth of certain body parts such as the prostate, penis, and scrotum; promoting male hair distribution; altering muscle mass and fat distribution; retaining essential body elements such as nitrogen, sodium, potassium, and phosphorus; decreasing urinary excretion of calcium; increasing protein anabolism while decreasing protein catabolism; stimulating red blood cell production.
Benzyl Alcohol (2%): This ingredient serves as a preservative in many injectable medicines. It ensures that the medicine remains sterile after opening and during multiple uses.

Pregnancy

Testenate Depot-250 Injection is not suitable during pregnancy. If you're pregnant or planning to conceive, discuss this with your doctor before starting on this medicine.

Breastfeeding

Testenate Depot-250 Injection should not be used by breastfeeding women. Make sure to consult your doctor to understand the potential risks and benefits.

Alcohol

Combining Testenate Depot-250 Injection with alcohol can strain the liver, disrupt hormonal balance, increase cardiovascular risks, and amplify mood changes, so it is advisable to limit or avoid alcohol while on this therapy.

Liver

Caution is advised when using Testenate Depot-250 Injection if you have liver problems. Discuss any liver-related issues with your doctor before starting this medicine as it may affect liver function.

Kidney

If you have a history of kidney problems, caution is advised before using Testenate Depot-250 Injection. Consult your doctor before administering this medicine.

Using Machines & Driving

Testenate Depot-250 Injection may cause dizziness. If you experience this, avoid driving or operating heavy machinery until you feel well again.

Allergy

If you're known to have allergies to any of the components of Testenate Depot-250 Injection, it's advised not to use this medicine. Consult your doctor for alternatives.

Children

Testenate Depot-250 Injection should only be administered to children under medical supervision due to risks of stunted growth and premature development. Always consult your doctor before giving any medicine to a child.

Older Patients

Older patients should use Testenate Depot-250 Injection under medical supervision as they may be more susceptible to its side effects. Caution is advised for patients above 70 years of age who might also have liver and kidney issues or might be on other medications. Your doctor will guide you based on your health status.

Drug-Drug Interactions

Testenate Depot-250 Injection interacts with the following medicines:

Anticoagulants: Medicines like warfarin or heparin may have their effects altered when used alongside Testenate Depot-250 Injection. This could potentially increase your risk of bleeding.
Antidiabetic Medicines: If you're taking medications such as metformin or insulin, Testenate Depot-250 Injection can affect their effectiveness, possibly impacting your blood sugar control.
Immunosuppressants: Medicines like cyclosporine or danazol may have enhanced effects when taken with Testenate Depot-250 Injection. This could lead to increased side effects.
Corticosteroids: Using corticosteroids like prednisolone in combination with Testenate Depot-250 Injection might increase the risk of water retention and swelling (edema).
Nonsteroidal Anti-inflammatory Drugs (NSAIDs): Taking NSAIDs like ibuprofen or naproxen alongside Testenate Depot-250 Injection could alter their anti-inflammatory effects.

Drug-Food Interactions

No specific food interactions have been established for Testenate Depot-250 Injection. It's always a good idea to maintain a balanced diet while on any medication.

Drug-Disease Interactions

Testenate Depot-250 Injection interacts with the following diseases:

Prostate Enlargement: Patients with an enlarged prostate should use this medicine cautiously as it could worsen their condition.
Heart Disease: Individuals with heart ailments may experience complications from using Testenate Depot-250 Injection as it can affect fluid balance in the body.
Liver Disease: Those with liver disease should be careful when using this medication, as it may exacerbate their condition.
Kidney Disease: Patients suffering from kidney ailments should use Testenate Depot-250 Injection with caution, as it might impact the function of their kidneys.

Daily Dose

Your doctor will prescribe the required dose of Testenate Depot-250 Injection, which might vary based on your health condition and how you respond to the medicine. Always follow the prescribed dosage and avoid any alterations without consulting your doctor.

Over Dose

An overdose of Testenate Depot-250 Injection might lead to symptoms such as acne, headache, weight gain, or mood changes like aggression or depression. If you suspect an overdose, it's advisable to inform your doctor promptly.

Missed Dose

If you forget to get your scheduled injection of Testenate Depot-250 Injection, try to make the appointment as soon as you remember. However, if it's close to the time for your next dose, just skip the missed one and continue with your regular schedule. Always consult your doctor before making any changes to your dosage.

Keep Testenate Depot-250 Injection in a cool place at a controlled room temperature of 25°C.
Protect it from direct sunlight and heat.
Make sure it's kept well away from children's reach.
Do not freeze.
Testenate Depot-250 Injection should be discarded if any visible particle appear.

If you're dealing with low testosterone levels, incorporating foods rich in vitamin D and zinc, such as fish and shellfish, into your diet might help boost your hormone levels naturally.
Regular moderate exercise can also be beneficial. It helps maintain muscle mass and strength - two aspects often affected by testosterone deficiency.

Fact Box

Available Dosage Types	Injection
Habit Forming	No
Ailment	Male Hypogonadism, Delayed Puberty, Female-to-Male Transgender Support
Drug Category	Androgen Medication
Therapeutic Category	Testosterone Replacement

What does the Testenate Depot-250 Injection contain?

The Testenate Depot-250 Injection contains 250 mg of testosterone enanthate.

How is the Testenate Depot-250 Injection administered?

This injection is administered as a deep intramuscular injection, usually into the gluteal muscle, by a doctor.

Who can use Testenate Depot-250 Injection?

This medicine is used to manage conditions such as male hypogonadism, and delayed puberty, and can also support female-to-male transgender individuals.

Who should avoid using Testenate Depot-250 Injection?

Individuals with known hypersensitivity to the medicine or its components, male breast cancer patients, and women who are pregnant should avoid using this medicine.

What are some common side effects of Testenate Depot-250 Injection?

Common side effects include acne, injection site discomfort, hair loss, mood changes, weight gain, abnormal liver function tests, and sleep apnea among others. Please consult your doctor if any of these persist or worsen.

What precautions are advised while using Testenate Depot-250 Injection?

Use with caution if you have prostate enlargement, heart disease, kidney disease or liver disease. Also, elderly patients should use this medicine with caution.

Can other medicines affect how Testenate Depot-250 Injection works?

Yes, certain medicines like oral anticoagulants and antidiabetic medicines can interact with Testenate Depot-250 Injection. Always consult your doctor before starting any new medicine.

Last Updated On 13 May. 2025 | 9:58AM (IST)

Certified Content

Written by

Dr Nikita Lobo

Medical Content Reviewer | 8 years

BDS, MDS

Reviewed by

Dr. Divya Chauhan

Medical Content Writer & Reviewer | 7 years

BAMS, APG, PG

Check out Editorial Policy

Manufacturer details

No 21 Damodardas, Main Road, Fort, Mumbai - 400001, Sukhadvala Marg

Country of origin: INDIA

Expiry on or after: March 2026

In case of any issues, contact us:

support@truemeds.in|09240250346

Address: 6th floor, Urmi Corporate Park Solaris, Saki Vihar Road, Andheri East, Mumbai 400071

References

Testosterone injection: MedlinePlus drug information. (n.d.). https://medlineplus.gov/druginfo/meds/a614041.html
PubChem. (n.d.-ag). Testosterone. PubChem. https://pubchem.ncbi.nlm.nih.gov/compound/6013
Testosterone: Uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB00624
Benzyl alcohol: Uses, Interactions, Mechanism of Action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB06770
PubChem. (n.d.-b). Benzyl alcohol. PubChem. https://pubchem.ncbi.nlm.nih.gov/compound/244

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We, at Truemeds make a diligent attempt to deliver accurate, expert- drafted and thoroughly reviewed medicine related information to our consumers. However, it should, by no means, be considered a substitute for prescription from a certified doctor or a trustworthy doctor-patient relationship. In fact we detest any form of self medication without expert advice. The sole purpose of the information on our portal is to educate our consumers, which helps improve the communication between a doctor and a patient. The information by no means is complete in its entirety and should not be used to diagnose or treat any medical condition. No amount of information can replace the experience and expertise of a doctor, therefore his/her advice always holds priority and should be followed appropriately.

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CIN: U62099MH2019PTC320566

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