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SoriFIX Ointment is a combination topical medication used to manage symptoms of psoriasis, a chronic skin condition. It combines a topical steroid (calcipotriol) and a Vitamin D analogue (betamethasone). This formulation helps reduce the excessive growth of skin cells while suppressing inflammation, redness, swelling, and itching associated with psoriasis.
SoriFIX Ointment used for the effective management of plaque psoriasis, a skin condition characterized by raised, red patches with silvery scales. It works to reduce skin redness and swelling while soothing irritation associated with the lesions. The ointment also provides moisturizing relief to hydrate the dry and scaly affected skin areas.
Applying SoriFIX Ointment involves the following steps:
Ensure the affected skin area is clean and dry before application.
Apply a thin layer of the prescribed amount of SoriFIX Ointment to the affected area as directed by your doctor.
Gently massage until the ointment is fully absorbed into the skin.
Wash your hands after applying, unless your hands are being treated.
Remember, this ointment is for external use only. Avoid contact with your eyes, mouth, or other mucous membranes.
SoriFIX Ointment is applied topically.
While using SoriFIX Ointment, you might experience some of the following common side effects:
A sensation of burning, stinging, or itching at the site where the ointment is applied
Skin irritation, redness, or dryness
Skin peeling or flaking
Folliculitis: This is a condition that involves inflammation of your hair follicles and could cause small red bumps or pimples to develop around your hair follicles.
However, most side effects are mild and transient. If you notice any severe or persistent side effects, discontinue using the ointment and seek medical attention immediately.
SoriFIX Ointment may cause side effects like burning, stinging, itching, redness, dryness, peeling or folliculitis. These are usually mild, but if any side effects persist, discontinue use and consult a doctor.
SoriFIX Ointment is a combination medicine with two active ingredients that work together to manage psoriasis symptoms:
Calcipotriol (0.005%): This component is a synthetic form of vitamin D3, which slows down the excessive production of skin cells often seen in psoriasis.
Clobetasol Propionate (0.05%): As a potent corticosteroid, clobetasol propionate works to block the release of inflammatory substances in the body. Reducing redness, swelling, and itching associated with psoriasis is its primary function.
The combined action of calcipotriol and clobetasol propionate provides an effective approach in managing both inflammation and overproduction of skin cells in psoriasis.
Caution is advised while applying SoriFIX Ointment if you are pregnant. It is best to consult your doctor before using this medicine.
It is crucial to discuss with your doctor before applying SoriFIX Ointment if you are breastfeeding. The safety of the medication during lactation has not been well-established.
Interactions between alcohol and SoriFIX Ointment are very rare as it is a topical application. However, it’s always wise to discuss this with your doctor.
Since SoriFIX Ointment is used externally, it seldom interacts with liver conditions. If you have liver health issues, do discuss them with your doctor before using this medicine.
Similar to liver health, kidney diseases rarely interact with topical products like SoriFIX Ointment. Consult your doctor if you have any kidney-related concerns.
SoriFIX Ointment does not usually affect your ability to drive or operate machinery. However, if you experience side effects like dizziness or blurred vision, avoid such activities and speak to your doctor.
If you are allergic to calcipotriol, clobetasol propionate or any other ingredients in SoriFIX Ointment, avoid its use. Speak to your doctor about alternative options.
SoriFIX Ointment is meant for adult use. Avoid giving this medicine to children under 18 years of age without a doctor's advice.
Older patients should apply SoriFIX Ointment under medical supervision as they may be more susceptible to its side effects. Your doctor will guide you based on your health status.
SoriFIX Ointment Interacts with the Following Medicines:
Corticosteroids: When you apply SoriFIX Ointment and simultaneously take other corticosteroids, whether orally or topically, the risk of side effects might increase because both medicines work in similar ways. Medicines like prednisone, hydrocortisone, and betamethasone are examples of corticosteroids.
Vitamin D Supplements: If you're taking vitamin D supplements while applying SoriFIX Ointment, you could be at risk of developing hypercalcaemia - a condition where there is too much calcium in your blood. Supplements like cholecalciferol and ergocalciferol can cause this interaction.
There are no known food interactions with SoriFIX Ointment. You can continue your regular diet unless advised otherwise by your doctor.
SoriFIX Ointment Interacts with the Following Diseases:
Hypercalcaemia: If you have high levels of calcium in your blood, using SoriFIX Ointment may worsen your condition as one of its active ingredients, calcipotriol, is a form of vitamin D which helps absorb calcium in the body.
Adrenal Insufficiency: Clobetasol propionate present in SoriFIX Ointment is a potent corticosteroid which can affect adrenal gland function if absorbed into the bloodstream. Caution should be exercised if you have adrenal insufficiency.
Your doctor will instruct you on how often to apply SoriFIX Ointment. The recommended amount may vary based on the severity of your psoriasis and your reaction to the medication. Always follow your doctor's advice and avoid exceeding the prescribed dosage.
If you realise you've applied too much of SoriFIX Ointment, don't panic. Simply wipe off the excess ointment with a clean tissue or cloth. If you notice persisting or worsening symptoms, inform your doctor.
If you forget to apply SoriFIX Ointment at the scheduled time, do so as soon as you remember it. However, if it's nearly time for the next application, skip the missed dose and continue with your usual schedule. Do not increase your dosage without consulting your doctor.
Store SoriFIX Ointment at room temperature, ideally below 25°C.
Keep the product away from direct sunlight and moisture.
Do not freeze.
Ensure the tube is tightly closed when not in use.
For safety, keep it out of the reach of children.
Since psoriasis may be worsened by stress, adopting relaxation techniques such as yoga or meditation could help manage flare-ups.
A diet rich in fruits, vegetables, lean proteins and whole grains might help enhance your overall health and keep your skin nourished, potentially easing psoriasis symptoms.
| Available Dosage Types | Ointment |
| Habit Forming | No |
| Ailment | Plaque Psoriasis |
| Drug Category | Corticosteroid, Vitamin D3 Analog |
| Therapeutic Category | Antipsoriatic |
SoriFIX Ointment is used to manage symptoms of plaque psoriasis in adults, such as redness, itching, swelling, and skin irritation. It also moisturises affected areas.
SoriFIX Ointment contains calcipotriol and clobetasol propionate. Calcipotriol slows down excessive skin cell production, while clobetasol propionate reduces inflammation and itching.
Apply a thin layer of the ointment to the affected skin areas once or twice daily, as advised by your doctor. Massage it gently until fully absorbed.
The safety of using SoriFIX Ointment during pregnancy or breastfeeding has not been established. Always consult your doctor if you are pregnant or planning to conceive.
Inform your doctor about all medications, supplements, and herbal products you are taking before starting treatment with SoriFIX Ointment to prevent potential medicine interactions.
If you experience side effects like burning, itching or skin peeling, consult your doctor. Discontinue use and seek medical attention immediately for severe side effects.
Store it at room temperature below 25°C. Protect it from direct sunlight and moisture. Keep it out of reach of children and pets.
Check out Editorial Policy
Calcipotriol: Uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB02300
Clobetasol propionate: Uses, Interactions, Mechanism of Action | DrugBank Online. (n.d.-b). DrugBank. https://go.drugbank.com/drugs/DB01013
DailyMed. (n.d.). Clobetasol propionate. U.S. National Library of Medicine. Retrieved April 1, 2024, from https://dailymed.nlm.nih.gov/dailymed/fda/fdaDrugXsl.cfm?setid=fb29b17b-96af-4a78-bc91-83cf8c5c2b1d&type=display
Desai, S., Draelos, Z., Feldman, S., & Jackson, J. M. (2021). A phase 3, randomized, double-blind, vehicle-controlled, multicenter, parallel group trial investigating the efficacy and safety of clobetasol propionate cream, 0.025% in the treatment of moderate to severe plaque psoriasis for 14 days. SKIN The Journal of Cutaneous Medicine, 5(6), s33. https://jofskin.org/index.php/skin/article/view/1384
Safety and efficacy of adding topical clobetasol propionate to etanercept in patients with moderate to severe plaque psoriasis. (2013). Journal of the American Academy of Dermatology, 68(4), AB211. https://linkinghub.elsevier.com/retrieve/pii/S0190962212021494
Das, K., Ranjan, R., Kumar, P., & Chandra, S. (2024). A comparative study of the effectiveness and safety of topical calcipotriol and topical methotrexate in chronic plaque psoriasis. Cureus. https://doi.org/10.7759/cureus.59878
We, at Truemeds make a diligent attempt to deliver accurate, expert- drafted and thoroughly reviewed medicine related information to our consumers. However, it should, by no means, be considered a substitute for prescription from a certified doctor or a trustworthy doctor-patient relationship. In fact we detest any form of self medication without expert advice. The sole purpose of the information on our portal is to educate our consumers, which helps improve the communication between a doctor and a patient. The information by no means is complete in its entirety and should not be used to diagnose or treat any medical condition. No amount of information can replace the experience and expertise of a doctor, therefore his/her advice always holds priority and should be followed appropriately.
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