CompositionSibolone 2.5 Tablet is used to relieve menopausal symptoms, such as hot flushes, night sweats and vaginal dryness, in women whose last period was at least 12 months ago. It is a single-ingredient medicine containing tibolone 2.5mg, which belongs to a group of medicines used for hormone replacement therapy (HRT).
Tibolone acts like a mix of female hormones (oestrogen and progestogen) and a weak male hormone in different parts of the body. It is also used to help prevent bone thinning (osteoporosis) in women at high risk of fractures when other treatments are unsuitable. Take one tablet a day at the same time, with water, as prescribed. It may take a few weeks for symptoms to improve.
Regular exercise, a balanced diet with enough calcium and vitamin D, not smoking and limiting alcohol and caffeine can help with menopausal symptoms and bone health.
Like other HRT, this medicine slightly increases the risk of breast cancer and stroke, and the risk of stroke rises with age, so your doctor will use the lowest effective treatment and review it at least yearly. Do not take it if you are pregnant, have unexplained vaginal bleeding, breast or womb cancer or a history of it, a recent stroke, heart attack or blood clot, or liver disease. Before starting, tell your doctor about migraine, epilepsy, diabetes, high blood pressure or high cholesterol, and other medicines you take, especially blood thinners. Attend regular breast screening. Seek medical help straight away for vaginal bleeding after the first few months, a breast lump, pain or swelling in one leg, chest pain, sudden breathlessness, or signs of a stroke such as sudden weakness or difficulty speaking.
