Pentate Dsr 10/40Mg Tablet 10

Morepen Laboratories Limited

Strip of 10 Units

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Prescription required for this medicine

Store Below 30° C

Composition

Domperidone (10 Mg) + Pantoprazole (40 Mg)

Pentate DSR Capsule is used to manage gastro-oesophageal reflux disease (GERD). It is also used for peptic ulcers and indigestion, which cause heartburn, chest discomfort, bloating, nausea and stomach discomfort.

It combines a proton pump inhibitor, which reduces stomach acid, with a prokinetic agent, which improves the movement of food through the digestive tract.

Take the capsule as prescribed, usually before food, and continue for the duration your doctor advises.

Tell your doctor about your medical history and any ongoing medicines before starting.

Pentate DSR Capsule is used to manage acid reflux and indigestion.

Uses of Pentate DSR Capsule are:

GERD: Relieves heartburn and chest discomfort caused by acid flowing back into the food pipe.
Peptic Ulcers: Supports healing of ulcers in the stomach, food pipe and small intestine.
Indigestion: Eases bloating, nausea and stomach discomfort.

To use Pentate DSR Capsule correctly:

Swallow the capsule whole with a glass of water.
Refrain from crushing or chewing the capsule.
Never exceed the recommended dose without consulting your doctor.
Do not stop taking this medicine without speaking to your doctor first.

Pentate DSR Capsule is taken orally.

Pentate DSR Capsule may cause some side effects that are usually mild and go away as your body adjusts to the medicine.

A few common side effects of Pentate DSR Capsule:

Digestive: Feeling sick (nausea), vomiting, loose motions (diarrhoea), stomach pain and gas.
Nervous System: Headache and dizziness.
Other: Dryness of the mouth.

If side effects do not improve or become serious, speak to your doctor right away.

Management Of Side Effects:

Most side effects are temporary and generally harmless, which resolve upon discontinuing the use of Pentate DSR Capsule. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

Here are some general guidelines for managing common side effects:

Nausea: Try taking Pentate DSR Capsule with food.
Stomach pain: If you experience abdominal discomfort after taking this medicine, consider taking it after a meal.

Pentate DSR Capsule contains two active ingredients that work together to alleviate gastrointestinal symptoms:

Pantoprazole (40 mg): This is a proton pump inhibitor. It works by blocking an enzyme system in the stomach's cells, reducing the production of stomach acid. This in turn helps heal peptic ulcers and reduces symptoms of GERD.
Domperidone (10 mg): As a prokinetic agent, domperidone increases the movement of the gut. It does this by blocking dopamine receptors in the gut. This action helps prevent acid reflux by increasing the tone of the lower esophagus and promoting faster emptying of the stomach.

Pregnancy

It is best to consult your doctor before taking Pentate DSR Capsule if you are pregnant. This medicine should only be used if the potential benefits outweigh the risks.

Breastfeeding

If you are breastfeeding, you should discuss with your doctor before using Pentate DSR Capsule. Your doctor will guide you based on the potential risks and benefits.

Alcohol

Caution is advised when consuming alcohol while taking Pentate DSR Capsule. It's better to discuss this with your doctor.

Liver

Pentate DSR Capsule is not recommended if you have severe liver diseases. If you have mild to moderate liver problems, it's advisable to consult your doctor before starting this medicine.

Kidney

If you have a history of kidney issues, caution is advised before using Pentate DSR Capsule. It's a good idea to consult your doctor before taking this medicine.

Use In Driving And Operating Machinery

This medicine may cause dizziness or blurred vision in some people. If you experience these effects, avoid driving or operating machinery until you feel well again.

Allergy

If you are allergic to domperidone or pantoprazole, do not take Pentate DSR Capsule. Always inform your doctor about your allergies beforehand.

Children

The safety and efficacy of Pentate DSR Capsule in children under 18 years of age have not been established. It's best to consult your doctor before giving this medicine to a child.

Older Patients

Older patients should take Pentate DSR Capsule under medical supervision as they may be more susceptible to its side effects. Caution is advised if patients are above 70 years of age. Your doctor will guide you based on your health status.

Drug-Drug Interactions

Pentate DSR Capsule interacts with the following medicines:

Antifungals: When taken with antifungal medicines like ketoconazole or itraconazole, the effectiveness of Pentate DSR Capsule might be reduced as these antifungals affect its absorption.
Antibiotics: Medicines like erythromycin and clarithromycin can interfere with the way Pentate DSR Capsule works, possibly leading to increased side effects.
HIV medications: The combination of Pentate DSR Capsule with HIV medications such as atazanavir or nelfinavir can alter their effects.
Blood thinners: Concurrent use of blood thinners like warfarin can increase the risk of bleeding due to interactions with this capsule.
Diuretics: Diuretics such as furosemide may interact with Pentate DSR Capsule, potentially leading to an imbalance in body salts.
Antidepressants: Pentate DSR Capsule might interact with antidepressants like citalopram or escitalopram, altering their effects.

Drug-Food Interactions

Certain foods may interact with Pentate DSR Capsule:

Acidic Foods: Foods high in acid content, such as citrus fruits and tomatoes, may increase stomach acid production and reduce the effectiveness of this medicine.

Drug-Disease Interactions

Pentate DSR Capsule interacts with the following diseases:

Liver Disease: Patients with severe liver disease should use this medication cautiously as it could exacerbate their condition.
Cardiac Arrhythmias: Those with a history of heart rhythm disorders should exercise caution when using this medicine as it could potentially worsen their condition.

Daily Dose

Your doctor will determine the daily dose of Pentate DSR Capsule for you. This will depend on factors such as the severity of your condition and your response to the medication. It's vital to adhere to your doctor's instructions and not exceed the prescribed dose.

Over Dose

If you accidentally take more than the prescribed dose of Pentate DSR Capsule, you may experience common side effects like headache, dizziness, and stomach discomfort. Do not panic, but do let your doctor know about this.

Missed Dose

In case you forget to take your scheduled dose of Pentate DSR Capsule, take it as soon as you remember. However, if it's near the time for your next dose, just skip the missed one and continue with your regular schedule. Under no circumstances should you increase your dosage without consulting your doctor.

Keep Pentate DSR Capsule in its original packaging.
Store at room temperature, ideally below 30°C.
Avoid exposing the capsule to direct sunlight and moisture.
Always keep this medicine out of reach from children.
Remember to use the capsule before it reaches its expiry date.

To manage gastroesophageal reflux disease (GERD), try reducing your intake of spicy and fatty foods, which can trigger acid reflux.
If you're dealing with peptic ulcers, consider eating smaller, frequent meals instead of three large ones. This can help reduce stress on your digestive system.
Remember: these are general suggestions. Your doctor may give you personalised advice based on your specific condition and health status.

Fact Box

Dosage Forms Available	capsule
Habit Forming	No
Ailment	Gastroesophageal Reflux Disease, Peptic Ulcers, Indigestion
Drug Category	Prokinetic Agent, Proton Pump Inhibitor
Therapeutic Category	Gastrointestinal Medication

What is Pentate DSR Capsule used for?

Pentate DSR Capsule helps manage symptoms of gastroesophageal reflux disease (GERD), peptic ulcers and indigestion.

How does Pentate DSR Capsule work?

It contains pantoprazole, reducing stomach acid production, and domperidone, enhancing gut movement to prevent acid reflux.

How should I take Pentate DSR Capsule?

Take it orally before breakfast. Swallow the capsule whole with a glass of water.

What are the side effects of Pentate DSR Capsule?

Common side effects include headaches, dizziness, nausea, vomiting, stomach pain, flatulence and dry mouth.

Who should not take Pentate DSR Capsule?

Those allergic to domperidone or pantoprazole, with severe liver impairment or a history of cardiac arrhythmias should not take this medicine.

Can I take other medicines with Pentate DSR Capsule?

Certain medicines may interact with this capsule. Always inform your doctor about all medications you're taking.

How should I store Pentate DSR Capsule?

Store at room temperature (below 30°C) in a dry place, away from direct sunlight and moisture.

Last Updated On 31 Jul. 2026 | 12:37PM (IST)

Certified Content

Written by

Ashmita Borgohain

Medical Content Writer | 14 years

MSc (Applied Genetics)

Reviewed by

Dr. Chhavi Rosha

Medical Content Writer | 10 years

BAMS, FMC, MD Resident

Check out Editorial Policy

Manufacturer details

218/19, Midas Sahar Plaza, M V Road, J B Nagar, Mumbai, Maharashtra 400059

Country of origin: INDIA

Expiry on or after: January 2027

In case of any issues, contact us:

support@truemeds.in|09240250346

Address: 6th floor, Urmi Corporate Park Solaris, Saki Vihar Road, Andheri East, Mumbai 400071

References

NHS. (n.d.). Domperidone: a medicine used to relieve feelings of sickness. NHS. Retrieved 1 April 2024, from https://www.nhs.uk/medicines/domperidone/
NHS. (n.d.). Pantoprazole: a medicine used to reduce stomach acid. NHS. Retrieved 1 April 2024, from https://www.nhs.uk/medicines/pantoprazole/
U.S. Food and Drug Administration. (n.d.). Drug Approval Package: PROTONIX (pantoprazole sodium) Delayed Release capsules. U.S. Food and Drug Administration. Retrieved 1 April 2024, from https://www.accessdata.fda.gov/drugsatfda_docs/label/2007/022020lbl.pdf
U.S. Food and Drug Administration. (2018). Guidance for Industry: Population Pharmacokinetics. U.S. Food and Drug Administration. Retrieved 1 April 2024, from https://www.fda.gov/media/112904/download

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Disclaimer

We, at Truemeds make a diligent attempt to deliver accurate, expert- drafted and thoroughly reviewed medicine related information to our consumers. However, it should, by no means, be considered a substitute for prescription from a certified doctor or a trustworthy doctor-patient relationship. In fact we detest any form of self medication without expert advice. The sole purpose of the information on our portal is to educate our consumers, which helps improve the communication between a doctor and a patient. The information by no means is complete in its entirety and should not be used to diagnose or treat any medical condition. No amount of information can replace the experience and expertise of a doctor, therefore his/her advice always holds priority and should be followed appropriately.

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Registered Office Address

Intellihealth Solutions Private Limited

Unit-301 & 304, Lightbridge Tunga Village, Saki Vihar Rd, Chandivali, Powai, Mumbai, Maharashtra, India, 400072.

CIN: U62099MH2019PTC320566

Telephone:09240250346

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Name: Kishor Kumar

Email: grievance-officer@truemeds.in

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