Noxagion 40 Injection 0.4Ml

Noxagion 40 Injection 0.4ml is used to prevent blood clots in the veins.

Uses of Noxagion 40 Injection 0.4ml are:

• Prevention of blood clots after surgery: This medicine helps reduce the risk of deep vein thrombosis (clots in the deep veins of the legs) and pulmonary embolism (clots that travel to the lungs) after operations that carry a moderate or high risk of clots, such as abdominal surgery and major hip or knee replacement.
• Prevention of blood clots in bedridden patients: It is used for adults whose movement is severely restricted by an acute illness, such as heart failure, respiratory failure or serious infection, to stop harmful clots from forming.
• Management of existing deep vein thrombosis: This medicine is used to manage confirmed clots in the deep veins, sometimes in patients with pulmonary embolism.
• Management of certain heart conditions: It is used in unstable angina (chest pain at rest) and heart attack, given together with aspirin.
• Prevention of clotting during dialysis: This medicine prevents clotting in the dialysis machine circuit during haemodialysis.

Administer Noxagion 40 Injection 0.4ml as follows:

• This medicine is given as an injection into the fatty tissue just under the skin, usually around the abdomen.
• It is administered by a nurse or doctor.
• Rotate the injection site between the left and right sides of the abdomen.
• Consult your doctor for specific advice while on the course of this medicine.

Noxagion 40 Injection 0.4ml is administered subcutaneously.

Noxagion 40 Injection 0.4ml contains enoxaparin sodium (40 mg in 0.4 mL), which works on the body as follows:

• Enhances antithrombin III activity: Enoxaparin binds to a natural blood protein called antithrombin III, which acts as the body's own brake on clotting. This binding greatly speeds up the rate at which antithrombin III switches off clotting enzymes.
• Inhibits Factor Xa: By enhancing antithrombin activity against Factor Xa, enoxaparin reduces thrombin generation and subsequent fibrin formation, thereby reducing blood clot formation.
• Reduces thrombin activity: Enoxaparin also inhibits thrombin (Factor IIa), another key clotting enzyme, though to a lesser extent than Factor Xa. This further reduces the blood's ability to form harmful clots.
• Prevents clot extension: By blocking these clotting enzymes, enoxaparin stops existing clots from growing larger while the body's natural systems break them down over time.

• Store the pre-filled syringe below 25 degrees Celsius in its original carton to protect it from light.
• Do not freeze the medicine.
• Keep the syringe away from excess heat and moisture, and do not store it in a bathroom.
• Keep out of the sight and reach of children.
• Do not use after the expiry date printed on the pack.

• Include iron-rich foods in your regular diet: Foods such as lentils, beans, leafy green vegetables and fortified cereals can help support healthy iron levels, particularly if you experience repeated blood loss
• Take care to prevent injuries: Avoid activities that may cause cuts, bruises, or falls; use a soft toothbrush; and be careful when shaving.