Gluriza M 0.5 Tablet 10

Gluriza M 0.5 Tablet 10 interacts with the following medicines:

• Other blood glucose lowering medicines: When you take insulin or other antidiabetic medicines like sitagliptin or pioglitazone alongside this tablet, your blood glucose may drop too low, causing hypoglycaemia (low blood sugar).

• Blood pressure medicines: Medicines like enalapril, lisinopril or other ACE inhibitors may lower your blood glucose further when combined with this tablet, raising the risk of hypoglycaemia.

• Antifungal medicines: Fluconazole can increase glimepiride exposure by inhibiting its metabolism, thereby increasing the risk of hypoglycaemia. Your doctor may recommend closer blood glucose monitoring or dose adjustment.

• NSAIDs and salicylates: Certain anti-inflammatory medicines may increase the risk of hypoglycaemia with glimepiride. NSAIDs may also impair kidney function, potentially increasing metformin-related risks. Consult your doctor before using them regularly.

• Steroid medicines: Corticosteroids like prednisolone or dexamethasone weaken the glucose-lowering action of this tablet, which may raise your blood glucose levels.

• Diuretics: Certain diuretics, particularly thiazides, may increase blood glucose levels. Diuretics can also contribute to dehydration or changes in kidney function, potentially increasing the risk of metformin-related complications.

Gluriza M 0.5 Tablet 10 interacts with the following diseases:

• Heart failure: Decompensated heart failure (when your heart cannot pump enough blood) reduces oxygen to tissues and raises the risk of lactic acidosis with the metformin component.

• Respiratory disease: Severe breathing problems or lung failure can cause tissue hypoxia (low oxygen), which increases the risk of lactic acidosis.

The daily dose of Gluriza M 0.5 Tablet 10 should be taken as prescribed by your doctor. The dosage may change based on individual factors such as the severity of your diabetes and your response to the medicine. It is important to follow the prescribed dosage and not exceed it without consulting your doctor.

Taking too much of Gluriza M 0.5 Tablet 10 may cause severe hypoglycaemia due to glimepiride, with symptoms such as sweating, shaking, confusion, seizures or loss of consciousness. Metformin overdose may cause lactic acidosis, with symptoms such as severe weakness, vomiting, abdominal pain, rapid breathing and drowsiness. Seek emergency medical attention if an overdose is suspected.

If you miss a dose, take it with food when you remember, unless it is nearly time for your next scheduled dose. In that case, skip the missed dose and continue your regular schedule. Never take a double dose to compensate for a missed one.