Gate GM 80/500 MG Tablet 10

Gates India Pvt Ltd

Strip of 10 Units

Read Info

MRP ~~₹99~~

₹79.2

₹9.9/Units

20% off

*MRP inclusive of all taxes

100% genuine medicines

Safe & secure payments

15 days Easy returns

Prescription required for this medicine

Store Below 30^o C

Composition

Gliclazide (80 Mg) + Metformin (500 Mg)

Gate GM 80/500 MG Tablet 10 is used to manage type 2 diabetes mellitus. It combines two antidiabetic agents: gliclazide (80 mg) and metformin (500 mg). Gliclazide stimulates insulin release from the pancreas, while metformin decreases glucose production in the liver and improves insulin sensitivity. This combination helps control blood sugar levels effectively.

This medicine is prescribed when individual therapy with either of its components doesn't provide satisfactory control over the patient's blood sugar levels.

Before you begin taking this medicine, it's crucial to consult your doctor about your dosage and frequency based on your specific health condition. Ensure you inform your doctor about any pre-existing conditions or ongoing medicines you're currently on. If you notice any side effects while taking this medicine, consult your doctor immediately. Continue taking this medicine for the duration prescribed by your doctor for optimal results.

Gate GM 80/500 MG Tablet 10 is mainly used to manage type 2 diabetes mellitus in adults.

Swallow the tablet whole with a glass of water.
Do not crush or chew the tablet.
Take the medicine in the dosage and frequency prescribed by your doctor.
Do not stop taking this medicine without discussing it with your doctor.

Gate GM 80/500 MG Tablet 10 is taken orally.

Gate GM 80/500 MG Tablet 10 may have the following common side effects:

Nausea or vomiting
Stomach pain
Constipation
Diarrhoea
Headache
Dizziness
Blurred vision
Hypoglycaemia (low blood glucose levels)

Managing the Side Effects:

Most side effects are temporary and generally harmless, which resolve upon discontinuing the medicine. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

You can also effectively manage common side effects like nausea, vomiting, diarrhoea, or stomach pain at home by taking the medicine with food.

Gate GM 80/500 MG Tablet 10 works in the human body in the following ways:

Gliclazide (80 mg): Gliclazide belongs to the group of sulphonylureas. It helps control blood glucose levels by stimulating your pancreas to release more insulin.
Metformin hydrochloride (500 mg): Metformin hydrochloride is classified as a biguanide. Its primary function is to lower glucose production in the liver and reduce intestinal glucose absorption. Additionally, it enhances insulin sensitivity by promoting peripheral glucose uptake and utilisation. This activity, in turn, helps reduce high blood sugar levels.

Pregnancy

Gate GM 80/500 MG Tablet 10 is contraindicated in pregnancy as it may cause harm to the foetus. Always consult your doctor before taking this medicine.

Breastfeeding

This medicine is contraindicated while breastfeeding as it may pass into breast milk and adversely affect the nursing infant. Always consult your doctor before starting this medicine.

Alcohol

Avoid alcohol consumption while on this medication as it could increase the risk of lactic acidosis (lactic acid built up in your body). Always consult your doctor regarding alcohol intake.

Liver

This medicine is contraindicated in patients with severe liver disorders as it could increase their risk of developing lactic acidosis. If you have liver issues, discuss them with your doctor before starting this medication.

Kidney

For those with severe kidney problems, especially severe renal impairment, Gate GM 80/500 MG Tablet 10 is contraindicated. Always consult your doctor before taking this medicine.

Using Machines & Driving

This medicine may cause dizziness or blurred vision in some individuals. If you feel dizzy or unwell, avoid doing activities such as driving or operating machinery until you feel better.

Allergy

Avoid taking this medicine if you are allergic to gliclazide, metformin hydrochloride, or any other ingredients in the tablet. Always discuss your allergies with your doctor.

Children

This medicine is not intended for use in children below 18 years. Always consult your doctor before giving any medicine to a child.

Older Patients

Elderly patients may have decreased hepatic or renal function, which puts them at a higher risk of developing lactic acidosis when taking Gate GM 80/500 MG Tablet 10. Exercise caution and consult your doctor for guidance based on your health status.

Drug-Drug Interactions

Gate GM 80/500 MG Tablet 10 may interact with the following medications:

Diuretics: Medicines like furosemide or hydrochlorothiazide may decrease the blood glucose-lowering effect of this tablet.
Corticosteroids: Medicines like prednisone can reduce the effectiveness of Gate GM 80/500 MG Tablet 10 in managing blood sugar levels.
Angiotensin-converting enzyme (ACE) inhibitors: ACE inhibitors such as ramipril or lisinopril can enhance the medicine's blood sugar-lowering effect, causing extremely low blood sugar levels.
Other antidiabetic agents: Medicines like insulin or glimepiride may interact with this tablet, increasing the risk of low blood sugar.

Drug-Food Interactions

Gate GM 80/500 MG Tablet 10 may interact with certain foods, such as:

High-fibre diet: A diet rich in fibre, like whole grains, legumes, and vegetables, may decrease the absorption and effectiveness of metformin hydrochloride.

Drug-Disease Interactions

Gate GM 80/500 MG Tablet 10 may interact with the following diseases:

Type 1 diabetes: This medicine is contraindicated in patients with type 1 diabetes.
Diabetic ketoacidosis: Patients with diabetic ketoacidosis are also contraindicated from taking this medicine.
Liver or kidney disease: This medicine is contraindicated if you have severe liver or kidney problems, as it could increase your risk of developing lactic acidosis, a rare but serious condition.
Heart failure: People with heart conditions like congestive heart failure are also contraindicated from taking this medicine.

Daily Dose

Your doctor will determine the recommended daily dose of Gate GM 80/500 MG Tablet 10, depending on individual factors such as the severity of your condition and your response to the medication.

Over Dose

If you accidentally take more than the prescribed dose, it can lead to common side effects such as nausea, diarrhoea, or headache. If you experience these symptoms, inform your doctor promptly.

Missed Dose

If you forget to take a dose of the medicine, take it as soon as you remember. However, if it's nearly time for your next dose, skip the missed one and continue with your regular schedule. Never double your dose to compensate for a missed one without consulting your doctor.

Keep Gate GM 80/500 MG Tablet 10 in a dry place, protected from light and moisture.
Store it at room temperature, below 30°C.
Avoid storing the medicine in heat or direct sunlight, as this could affect its effectiveness.
Ensure this medicine is out of reach of children to prevent accidental consumption.
Always use the medicine before its expiry date.

Consider following a balanced diet low in sugar, which can help control blood glucose levels.
Regular physical activity can also aid in controlling your blood glucose levels. Try incorporating exercise into your daily routine, even if it's just a brisk walk. Always consult your doctor before starting any new exercise regimen.

Fact Box

Available Dosage Types	Tablet
Habit Forming	No
Ailment	Type 2 Diabetes Mellitus
Drug Category	Sulphonylurea, Biguanide
Therapeutic Category	Antidiabetic

What is Gate GM 80/500 MG Tablet 10 used for?

It's a medicine used to manage type 2 diabetes mellitus in adults, particularly when individual components of the medicine, gliclazide or metformin hydrochloride, cannot adequately control blood sugar levels.

How does Gate GM 80/500 MG Tablet 10 work?

This medicine contains two active ingredients. Gliclazide stimulates the pancreas to secrete more insulin in your body, while metformin hydrochloride reduces glucose production in the liver and lowers intestinal glucose absorption. Together, they help reduce blood glucose levels.

Can I take Gate GM 80/500 MG Tablet 10 if I'm pregnant or breastfeeding?

No, this medicine is contraindicated during pregnancy or breastfeeding as it may cause harm to the baby. Always consult your doctor for safer alternatives.

Can children take Gate GM 80/500 MG Tablet 10?

This medicine is not indicated for use in children below 18 years old. Always consult your doctor before giving this medicine to a child.

Are there any side effects of Gate GM 80/500 MG Tablet 10?

Yes, some people may experience side effects like diarrhoea, nausea, vomiting, and hypoglycaemia. If these symptoms persist, consult your doctor.

Can I drink alcohol while taking Gate GM 80/500 MG Tablet 10?

No, it's best to avoid alcohol intake while on this medication, as it can increase the risk of lactic acidosis. Always consult your doctor regarding alcohol consumption.

What should I do if I overdose on Gate GM 80/500 MG Tablet 10?

In case of an overdose, seek immediate medical attention. Overdosing may lead to conditions like dizziness, blurred vision, or hypoglycaemia.

Last Updated On 13 May. 2025 | 11:17AM (IST)

Certified Content

Written by

Ashmita Borgohain

Medical Content Writer | 12 years

MSc (Applied Genetics)

Reviewed by

Dr. Divya Chauhan

Medical Content Writer & Reviewer | 7 years

BAMS, APG, PG

Check out Editorial Policy

Manufacturer details

GATES INDIA PVT. LTD., 3RD FLOOR, BLDG. # 10, TOWER C, DLF CYBER CITY, PHASE 2, GURGAON, HARYANA 122002

Country of origin: INDIA

Expiry on or after: October 2025

In case of any issues, contact us:

support@truemeds.in|08069808861

Address: 6th floor, Urmi Corporate Park Solaris, Saki Vihar Road, Andheri East, Mumbai 400071

References

GLUCOPHAGE (metformin hydrochloride tablets). (n.d.). accessdata.fda.gov. https://www.accessdata.fda.gov/drugsatfda_docs/label/2000/21202lbl.pdf
Website, N. (2024c, March 26). Gliclazide. nhs.uk. https://www.nhs.uk/medicines/gliclazide/
Gliclazide: Uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB01120
Campbell, D., Lavielle, R., & Nathan, C. (1991). The mode of action and clinical pharmacology of gliclazide: a review. Diabetes Research and Clinical Practice, 14, S21–S36. https://doi.org/10.1016/0168-8227(91)90005-x
Corcoran, C., & Jacobs, T. F. (2023b, August 17). Metformin. StatPearls - NCBI Bookshelf. https://www.ncbi.nlm.nih.gov/books/NBK518983/#
Metformin: MedlinePlus drug information. (n.d.). https://medlineplus.gov/druginfo/meds/a696005.html
METFORMIN-INDUCED LACTIC ACIDOSIS COMPLICATED BY ACUTE LIVER FAILURE. (2023, October). journal.chestnet.org. https://journal.chestnet.org/article/S0012-3692(23)02332-2/fulltext

Was this product description useful?

15 people find this information helpful

Disclaimer

We, at Truemeds make a diligent attempt to deliver accurate, expert- drafted and thoroughly reviewed medicine related information to our consumers. However, it should, by no means, be considered a substitute for prescription from a certified doctor or a trustworthy doctor-patient relationship. In fact we detest any form of self medication without expert advice. The sole purpose of the information on our portal is to educate our consumers, which helps improve the communication between a doctor and a patient. The information by no means is complete in its entirety and should not be used to diagnose or treat any medical condition. No amount of information can replace the experience and expertise of a doctor, therefore his/her advice always holds priority and should be followed appropriately.

Recommended Substitute

50.1% CHEAPER

Gliclanux M 80 Tablet 10

Nicholas Healthcare Limited

Strip of 10 Units

₹49.4

₹4.94/Units

6452 users bought this instead

Quick links

Uses
Directions for Use
Route of Administration
Side Effects
Medicine Activity
Precautions & Warnings
Interactions
Dosage
Storage
Diet & Lifestyle
Fact Box
FAQs

More Products By Gates India Pvt Ltd

Multigates Multi Tablet 10

MRP~~₹500~~

₹425

15% OFF

Multigates Drops 15 ML

MRP~~₹81~~

₹64.8

20% OFF

Multigates Rich Tablet 10

MRP~~₹259~~

₹207.2

20% OFF

Braingate Gold Tablet 10

MRP~~₹395~~

₹316

20% OFF

Gateby Tablet 10

MRP~~₹54~~

₹43.2

20% OFF

Gazyme Syrup 200 ML

MRP~~₹168.75~~

₹135

20% OFF

Gacal Tablet 10

MRP~~₹42~~

₹33.6

20% OFF

Save 50.1% with Substitute

Gafer C Capsule 10

MRP~~₹77.12~~

₹61.7

20% OFF

Gatop D Tablet 10

MRP~~₹135~~

₹108

20% OFF

Save 50.1% with Substitute

Gacoril 45/1.25/2 MG Syrup 100 ML

MRP~~₹79.98~~

₹63.98

20% OFF

Progates Vannila Powder 200 GM

MRP~~₹330.51~~

₹297.46

10% OFF

Omegates D 10/20 MG Capsule 10

MRP~~₹115.17~~

₹92.14

20% OFF

Save 50.1% with Substitute

Gafer Tablet 10

MRP~~₹99~~

₹79.2

20% OFF

Abgates D 10/20 MG Tablet 10

MRP~~₹130~~

₹104

20% OFF

Save 50.1% with Substitute

First 650 MG Tablet 10

MRP~~₹39.48~~

₹31.58

20% OFF

Save 54.39% with Substitute

Growgates Tablet 10

MRP~~₹98~~

₹78.4

20% OFF

Acechos 100 MG Tablet 10

MRP~~₹29.96~~

₹23.97

20% OFF

Save 50.1% with Substitute

Gacal Syrup 200 ML

MRP~~₹193.91~~

₹155.13

20% OFF

Save 50.91% with Substitute

Braingates Syrup 150 ML

MRP~~₹790~~

₹632

20% OFF

First 500 MG Tablet 10

MRP~~₹9.11~~

₹7.29

20% OFF

Top-Selling Health Essentials

D Protin Vanilla Flavour Sugar Free Powder 500gm

MRP~~₹695~~

₹649.83

7% OFF

Prohance D Diabetes Care Chocolate Flavour Sugar Free Powder 400gm

MRP~~₹862~~

₹818.9

5% OFF

Ensure Diabetes Care Chocolate Flavour Refill Powder 200gm

MRP~~₹540~~

₹518.4

4% OFF

Fresubin Dm Cardamom Flavour Powder 400gm

MRP~~₹1054~~

₹948.6

10% OFF

Era Dn Capsule 10

MRP~~₹240.8~~

₹199.86

17% OFF

Vidavance Chocolate Flavour Powder Jar 200gm

MRP~~₹540~~

₹486

10% OFF

Health Articles

View All

Product Reviews

Top 10 Dry Cough Syrups: Benefits and Uses

Women's Health

How to Bring on Your Period: A Guide for Delayed Cycles

Ayurveda

People Are Putting Castor Oil on Their Belly Button—But What Does the Science Say?

Product Reviews

Best Stomach Pain Medicines in India for Fast & Effective Relief

Hair Care

Best Hair Growth Serums for Men & Women: Top Picks for Stronger Hair

Cold, Cough & Allergies

Best Sinus Medications: Effective Treatments for Sinus Relief

Fitness

Top 10 Pre-Workout Supplements in India for 2025

Product Reviews

Best Fever Tablets in India: Names, Dosage & How They Work

Ayurveda

Best Ayurvedic Medicines for Uric Acid – Natural Relief & Treatment

Cold, Cough & Allergies

Sore Throat Relief Guide: Medicines, Remedies & Tips

Aesthetic & Skin Care

How to Remove Skin Tags: Causes, Treatments & Home Remedies

Cold, Cough & Allergies

Cold Medicine for Adults: Everything You Need to Know

Company

About Us Health Article Health Stories Diseases & Health Conditions Ayurveda All Medicines All Brands Need Help FAQ

Social

Legal

Terms & Conditions Privacy Policy Editorial Policy Returns & Cancellations

Claim your complimentary health and fitness tips subscription and stay updated on our newest promotions.

Registered Office Address

Intellihealth Solutions Private Limited

Office Unit no. 1, 2, 5, & 7, 6th floor Urmi Corporate Park Solaris, Saki Vihar Rd, Opp. L&T Flyover, New Mhada Colony, Budhia Jadhav Wadi, Mumbai, Maharashtra 400072.

CIN: U85320MH2019PTC320566

Telephone:09240250346

Grievance Officer

Name: Chandrasekhar Swaminathan

Email: grievance-officer@truemeds.in

Download Truemeds

Manage your health with ease Download Truemeds today!Get easy access to medicine refills, health information, and more. With our app, you'll never have to wait in line again. Download now and start taking control of your health.