Eptoin Injection is prescribed for the management of generalized tonic-clonic seizures, a type of epilepsy, by stabilizing the electrical activity in the brain to prevent recurrent seizure episodes. This medication is also used in the prevention and treatment of seizures that occur during neurosurgery, providing crucial support for individuals undergoing brain surgeries or trauma.
Before starting the injection, it is vital to inform your doctor of any pre-existing medical conditions, other ongoing medications, or allergies to ensure safe and effective treatment. Some side effects may occur with its use, so if you experience any unusual symptoms, it is important to consult your healthcare provider immediately. Always follow the dosage prescribed and complete the full treatment to manage seizures effectively.
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Eptoin Injection 2ml
Abbott Healthcare Pvt. Ltd
Ampoule of 2 ML
Old MRP ₹13.32
MRP ₹12.49
₹10.37
₹6.25/ML
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CompositionAbout Eptoin Injection 2ml
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Uses of Eptoin Injection 2ml
Eptoin Injection is used to treat and control generalized tonic-clonic seizures and status epilepticus, a severe and prolonged seizure condition, by stabilizing electrical activity in the brain and preventing the spread of seizure activity. It is also administered to prevent and treat seizures during neurosurgical procedures, ensuring stable brain function during and after surgery.
Directions for Use of Eptoin Injection 2ml
- A health professional should administer Eptoin Injection under the supervision of a doctor. It is not recommended to be self-administered.
- If you have any concerns or questions about the timing or dosage of this injection, please consult your doctor.
Route of Administration
Eptoin Injection is given intravenously or intramuscularly.
Side Effects of Eptoin Injection 2ml
Eptoin Injection may cause common side effects such as redness and pain at the injection site, uncontrolled eye movement, slurred speech, decreased coordination, drowsiness, and mental confusion. If these side effects continue or worsen, contact your healthcare provider immediately for further guidance.
Management Of Side Effects:
Most of the side effects resolve on discontinuing the injection and are temporary and, in most cases, do not require medical attention. Avoid doing any task that requires mental alertness after taking this injection. If you experience severe or persistent side effects from this injection, consult your doctor.
How Eptoin Injection 2ml Works?
Eptoin Injection contains the following component:
- Phenytoin (50 mg/ml): It is an anticonvulsant that prevents the spread of seizure activity. It does this by affecting the functioning of certain parts of nerve cells in the brain to regulate brain excitability. This makes the nerve cells more stable to prevent the chances of seizures. It also helps stop seizures that might happen after surgery on the brain.
Safety Measures & Warnings
Pregnancy
Eptoin Injection is not recommended for pregnant women. It may harm the growing foetus. Consult your doctor to know the risks of using this injection during pregnancy.
Breastfeeding
Breastfeeding mothers should not take Eptoin Injection. It may pass to the infant through breast milk. Before taking this injection while breastfeeding, it is recommended to inform your doctor.
Alcohol
Alcohol should be strictly avoided while taking Eptoin Injection. Acute alcoholic intake may increase this injection's blood concentration, while chronic alcoholic use may decrease its concentration.
Liver
Eptoin Injection should be cautiously used in patients with liver disease. If you have a severe liver problem, consult your doctor about the dose before taking it.
Kidney
When taking Eptoin Injection, patients with kidney disease should exercise caution. If you have a severe kidney problem, it is advisable to consult your doctor before taking it.
Use In Driving And Operating Machinery
This injection may affect your mental or physical abilities to operate machinery or drive. After taking the injection, you may experience drowsiness, confusion, and coordination difficulty. Therefore, avoiding any attentive task is recommended after taking this medicine.
Allergy
If you are allergic to phenytoin, other hydantoins, or any other ingredient in Eptoin Injection, you should not take it. Read the label and check the ingredients in the injection to avoid allergic reactions.
Children
It is recommended to take the doctor’s advice before giving this medicine as your doctor will give the dosage of Eptoin injection according to your child’s age and weight before giving it to them.
Older Patients
Eptoin Injection clearance is decreased slightly in elderly patients, and lower or less frequent dosing may be required. They may also take other medications that can interact with this injection. Consult your doctor and discuss your prescription medications before taking this injection.
Interactions of Eptoin Injection 2ml
Drug-Drug Interactions
Eptoin Injection can interact with medications, including:
- Antihypertensives such as reserpine. The concomitant use may decrease the concentration of this injection in blood.
- Anti-epileptic agents such as felbamate, topiramate, oxcarbazepine, and diazepam. The concomitant use may increase the concentration of this injection in blood. Antiepileptics such as sodium valproate and valproic acid may increase or decrease the concentration of this injection in blood.
- Anticonvulsants such as ethosuximide. The concomitant use may increase the concentration of this injection in blood.
- Antituberculosis agents such as isoniazid. The concomitant use may increase the concentration of this injection in blood..
- Antifungals such as fluconazole, ketoconazole, itraconazole.The concomitant use may increase the concentration of this injection in blood.
- Antibiotics such as chloramphenicol. The concomitant use may increase the concentration of this injection in blood.
- Antianxiety medications such as chlordiazepoxide. The concomitant use may increase the concentration of this injection in blood.
- Gastric acid reducers such as cimetidine. The concomitant use may increase the concentration of this injection in blood.
- Estrogens. The concomitant use may increase the concentration of this injection in blood.
- Anticoagulants such as warfarin. The concomitant use may increase the concentration of this injection in blood.
- HIV medivations such as nelfinavir. The concomitant use may decrease the concentration of this injection in blood.
- Barbiturates such as phenobarbital. The concomitant use may increase or decrease the concentration of this injection in blood.
Drug-Disease Interactions
Eptoin Injection can interact with diseases, including:
- Heart disease: The risk of cardiovascular toxicity may increase if the infusion rate of this injection is high. This injection is contraindicated in patients with severe heart problems such as sinus bradycardia, sino-atrial block, second and third-degree A-V block, and patients with Adams-Stokes syndrome.
- Porphyria (a blood disorder): This injection may exacerbate porphyria.
Dosage of Eptoin Injection 2ml
Daily Dose
Take Eptoin Injection as directed by your doctor. The dosage may change based on individual factors such as the severity of the condition and response to treatment. It is important to follow the prescribed dosage and not exceed it without consulting your doctor.
Over Dose
If you take an excessive amount of Eptoin Injection by accident, it is essential to take immediate medical attention from your doctor or nearby hospital. Symptoms of an overdose include uncontrolled eye movement, lack of coordination, slurred speech, weakness, nausea, and vomiting.
Missed Dose
Your doctor will provide the instructions on when to give you this injection. It is unlikely that you will not be given the medicine as it has been prescribed. However, if you think you missed a dose, tell your doctor.
Storage
- Store this injection at a temperature below 30 ºC.
- Do not use this injection if you see crystals or deposits in the ampule.
- Keep this injection out of reach of children.
Special Dietary And Lifestyle Recommendation
- Ensure strict adherence to prescribed antiepileptic medications. Skipping doses can increase the risk of seizures.
- Maintain a regular sleep schedule and prioritise adequate sleep, as sleep deprivation can trigger seizures in some individuals.
- Alcohol can increase seizure risk; it's advisable to avoid it.
- Abide by fasting guidelines provided by your doctor before surgery, as fasting helps reduce the risk of aspiration during anesthesia induction.
- Adhere to your doctor’s instructions regarding medications, rest, and activity level.
Fact Box
| Dosage Forms Available | Injection |
| Habit Forming | No |
| Ailment | Control of generalised tonic-clonic status epilepticus, and for the prevention and treatment of seizures occurring during neurosurgery |
| Drug Category | Anticonvulsants |
| Therapeutic Category | Antiepileptic drugs |
Frequently Asked Questions (FAQs)
What is the route of Eptoin Injection?
This injection is typically administered intravenously (IV) or intramuscularly (IM), depending on the specific medical condition and doctor’s instructions.
What is the medicine class of Eptoin Injection?
This injection belongs to the class of medicines known as antiepileptics. It is primarily used to manage and prevent seizures in individuals with epilepsy.
Does Eptoin Injection affect the liver?
Yes, this injection can affect the liver in some individuals, potentially leading to liver function abnormalities or liver damage. Regular monitoring of liver function is essential while using this medication to detect and manage any potential liver-related issues.
What is the dose of Eptoin Injection?
The dosing for this injection varies depending on the individual's specific medical condition, age, weight, and response to the medication. The exact dosing regimen should be determined by a doctor based on the patient's needs and regular monitoring of blood levels of phenytoin to maintain therapeutic levels while avoiding toxicity.
What is Eptoin Injection used for?
How does Eptoin Injection work?
Can I drive after receiving Eptoin Injection?
Is Eptoin Injection safe during pregnancy?
Can I drink alcohol while using Eptoin Injection?
Does Eptoin Injection help with brain trauma?
What should I do if Eptoin Injection contains crystals?
Can breastfeeding mothers receive Eptoin Injection?
Does Eptoin Injection prevent surgical seizures?
What are the common side effects of Eptoin Injection?
Can Eptoin Injection treat status epilepticus?
How should Eptoin Injection be stored?
Is Eptoin Injection habit-forming?
Can Eptoin Injection cause mental confusion?
Should I avoid machinery after Eptoin Injection?
Can Eptoin Injection affect heart conditions?
Is Eptoin Injection safe for kidney patients?
What happens if I am allergic to Eptoin Injection?
Can Eptoin Injection affect my coordination?
Who should administer Eptoin Injection?
Does Eptoin Injection contain ethanol?
Can Eptoin Injection be used for children?
Why is sleep important with Eptoin Injection?
Can Eptoin Injection treat tonic-clonic seizures?
Does Eptoin Injection interact with warfarin?
Can elderly patients receive Eptoin Injection?
Should I fast before receiving Eptoin Injection?
What should I disclose before using Eptoin Injection?
Does Eptoin Injection cause speech issues?
Can Eptoin Injection cause site pain?
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Manufacturer details
Country of origin: INDIA
References
- Parenteral Dilantin® (Phenytoin Sodium Injection, USP) . (n.d.). Fda.gov. (Retrieved September 2023). https://www.accessdata.fda.gov/drugsatfda_docs/label/2011/010151s036lbl.pdf
- Phenytoin Sodium 50mg/ml Solution for Injection - Summary of Product Characteristics (SmPC) - (emc). (n.d.). Org.uk. (Retrieved September 2023). https://www.medicines.org.uk/emc/product/4326/smpc
- Phenytoin Injection. (n.d.). Medlineplus.Gov. (Retrieved September 2023). https://medlineplus.gov/druginfo/meds/a619062.html
- Misty D. Smith, Cameron S. Metcalf, and Karen S. Wilcox (2018).Pharmacotherapy of the Epilepsies. In Goodman & Gilman’s: The Pharmacological Basis of Therapeutics (13th ed., pp.309). essay, McGraw Hill Medical.
- Tripathi, K. D. (2019). Antiepileptic Drugs . In Essentials of Medical Pharmacology (8th ed., pp. 439). essay, Jaypee Brothers Medical Publishers.
- CDSCO. (n.d.). Gov.In. (Retrieved September 2023). https://cdscoonline.gov.in/CDSCO/Drugs
- PHENYTOIN SODIUM INJECTION USP 50 mg/mL STERILE. (n.d.). Hres.Ca. (Retrieved September 2023). https://pdf.hres.ca/dpd_pm/00045167.PDF
- Schein, H. (n.d.). PHENYTOIN SODIUM -phenytoin sodium injection. Nih.gov. (Retrieved September 2023). Retrieved September 26, 2023, from https://dailymed.nlm.nih.gov/dailymed/getFile.cfm?setid=a4f31068-73fb-4efb-b4ac-7d1b9fd9f79a&type=pdf
Disclaimer
We, at Truemeds make a diligent attempt to deliver accurate, expert- drafted and thoroughly reviewed medicine related information to our consumers. However, it should, by no means, be considered a substitute for prescription from a certified doctor or a trustworthy doctor-patient relationship. In fact we detest any form of self medication without expert advice. The sole purpose of the information on our portal is to educate our consumers, which helps improve the communication between a doctor and a patient. The information by no means is complete in its entirety and should not be used to diagnose or treat any medical condition. No amount of information can replace the experience and expertise of a doctor, therefore his/her advice always holds priority and should be followed appropriately.
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