Empagligen M 12.5/1000 Tablet 10

Tablets India Ltd

Strip of 10 Units

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Old MRP ₹425

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Prescription required for this medicine

Store Below 30° C

Composition

Empagliflozin (12.5 Mg) + Metformin (1000 Mg)

Strength:

12.5 MG

Empagligen M 12.5/1000 Tablet 10 is used to manage high blood sugar levels in adults with type 2 diabetes mellitus. It is a combination medicine that belongs to the class of antidiabetic medications.

In addition to controlling blood glucose levels, this medicine may help reduce the risk of cardiovascular death in diabetic patients with established heart disease. It can also lower the risk of hospitalisation for heart failure in certain patient groups when other treatments are not effective enough.

This medicine should be taken orally as directed by your doctor, typically with food. Before starting this treatment, inform your doctor about any existing medical conditions or other medicines you are taking. If you notice any unusual side effects while using this medicine, consult your doctor promptly.

Empagligen M 12.5/1000 Tablet 10 is used for the following:

Managing type 2 diabetes mellitus in adults
Improving glycemic control alongside diet and exercise
Reducing cardiovascular and heart failure risks in diabetic patients
Enhancing insulin sensitivity and reducing glucose production
Preventing diabetes-related complications

Follow these instructions while taking Empagligen M 12.5/1000 Tablet 10:

Swallow the tablet whole with a glass of water.
Do not crush, break or chew the tablet.
Take the medicine at the same time each day for the best results.
Follow your prescribed diabetic meal plan and maintain regular physical activity.
If you have questions about how to take this medicine, consult your doctor.

Empagligen M 12.5/1000 Tablet 10 is taken orally.

Empagligen M 12.5/1000 Tablet 10 may have the following common side effects:

Nausea
Diarrhoea
Abdominal discomfort
Increased urination frequency
Vaginal yeast infections: Women may experience itching, unusual discharge, or discomfort in the genital area.
Genital fungal infections: Men may develop redness, itching, or a rash on the genital area, particularly if uncircumcised.
Metallic taste in the mouth
Loss of appetite

Management Of Side Effects:

Most side effects are temporary and generally harmless and are resolved by discontinuing the use of Empagligen M 12.5/1000 Tablet 10. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

Here are some general guidelines for managing common side effects:

Nausea and abdominal discomfort: Taking Empagligen M 12.5/1000 Tablet 10 with food in the morning can help reduce these digestive effects.
Diarrhoea: This side effect often improves if you take the medicine with meals rather than on an empty stomach.

Empagligen M 12.5/1000 Tablet 10 contains two active ingredients:

Empagliflozin (12.5 mg): This component works by blocking sodium-glucose co-transporter 2 (SGLT2) in the kidneys, which prevents glucose reabsorption and causes excess sugar to be removed through urine.
Metformin (1000 mg): This component decreases glucose production in the liver, a process known as hepatic gluconeogenesis. It also improves insulin sensitivity in muscle tissues, allowing better glucose uptake, and reduces intestinal absorption of glucose.

Pregnancy

Caution is advised while taking Empagligen M 12.5/1000 Tablet 10 if you are pregnant. This medicine is generally not recommended during pregnancy, especially in the second and third trimesters. It is best to consult your doctor before taking this medicine.

Breastfeeding

Caution is advised while taking Empagligen M 12.5/1000 Tablet 10 if you are breastfeeding. It is best to consult your doctor before taking this medicine to understand the potential risks and benefits.

Alcohol

Avoid alcohol while taking Empagligen M 12.5/1000 Tablet 10. Alcohol increases your risk of developing lactic acidosis, a rare but serious side effect. It may also lower your blood sugar levels, leading to dizziness or fainting.

Liver

Caution is advised while taking Empagligen M 12.5/1000 Tablet 10 if you have liver problems. Your doctor should check your liver function before starting this medicine. Regular monitoring may be needed, as liver impairment can increase the risk of lactic acidosis.

Kidney

Caution is advised before using Empagligen M 12.5/1000 Tablet 10 if you have a history of any kidney problems. Your doctor should check your kidney function before and during treatment, as both active ingredients in this medicine are affected by kidney health.

Use In Driving And Operating Machinery

You may drive and use machines while taking Empagligen M 12.5/1000 Tablet 10 unless you experience dizziness or low blood sugar. If you notice these symptoms, avoid driving or operating heavy machinery until you feel better.

Allergy

Tell your doctor about any allergies you have before taking Empagligen M 12.5/1000 Tablet 10. If you develop symptoms like a skin rash, itching, swelling of the face or throat, or breathing difficulties after taking this medicine, seek medical help immediately.

Children

Empagligen M 12.5/1000 Tablet 10 is not recommended for use in children below 18 years of age. The safety and effectiveness of this medicine have not been established for children with type 2 diabetes.

Older Patients

Older patients should take Empagligen M 12.5/1000 Tablet 10 under medical supervision, as they may be more susceptible to side effects. Your doctor may adjust the dose based on your kidney function. Regular monitoring of kidney function is important while taking this medicine.

Drug-Drug Interactions

Empagligen M 12.5/1000 Tablet 10 interacts with the following medicines:

Diuretics: Medicines like furosemide or hydrochlorothiazide can increase the risk of dehydration and low blood pressure when taken with Empagligen M 12.5/1000 Tablet 10.
Insulin and sulfonylureas: Medicines like insulin glargine or glimepiride may increase the risk of low blood sugar (hypoglycaemia) when combined with this tablet.
NSAIDs: Medicines like ibuprofen or diclofenac may affect kidney function, which can increase the risk of side effects from metformin.
ACE inhibitors: Medicines like enalapril or ramipril require careful monitoring when used with this tablet, as they can affect kidney function.

Drug-Disease Interactions

Empagligen M 12.5/1000 Tablet 10 interacts with the following diseases:

Heart failure: In such cases, careful monitoring is required, as fluid balance changes from empagliflozin may affect heart function.
Diabetic ketoacidosis: This medicine may mask symptoms of this serious condition while still allowing it to develop.

Daily Dose

The daily dose of Empagligen M 12.5/1000 Tablet 10 should be taken as prescribed by your doctor. The dosage may be adjusted based on your kidney function and how well your body responds to the medication. Follow the prescribed dosage without exceeding it.

Over Dose

An overdose of this medicine may cause stomach discomfort, nausea, vomiting, diarrhoea, increased urination, and excessive thirst. You might also experience dizziness, weakness, and unusual muscle pain. Contact your doctor if these symptoms occur.

Missed Dose

If you forget to take your medicine, take it when you remember. If it's nearly time for your next dose, skip the missed one and continue with your regular schedule. Never double the dose to make up for a missed one.

Store Empagligen M 12.5/1000 Tablet 10 at room temperature below 30°C.
Keep away from direct sunlight, heat and moisture.
Store in the original packaging until you are ready to use it.
Keep out of reach of children and pets.
Do not use the medicine after the expiry date printed on the package.
Dispose of unused or expired tablets through pharmacy take-back programmes.

Follow a diabetic meal plan with limited refined carbohydrates and sugars. This helps maintain steady blood glucose levels and improves how your body responds to the medicine.
Engage in regular physical activity (at least 30 minutes daily), as this enhances insulin sensitivity and helps your muscles use glucose more effectively.

Fact Box

Dosage Forms Available	Tablet
Habit Forming	No
Ailment	Type 2 diabetes, hyperglycaemia
Drug Category	SGLT2 inhibitor + biguanide
Therapeutic Category	Antidiabetic

How to use Empagligen M 12.5/1000 Tablet 10?

Take this tablet with your meals. Swallow it whole with water. Don't crush or chew it. Taking it with food reduces stomach discomfort.

How does Empagligen M 12.5/1000 Tablet 10 work?

It works through two mechanisms. Empagliflozin removes excess sugar through urine, while metformin reduces glucose production in your liver and improves insulin sensitivity in muscles.

Can I drink alcohol while taking this medicine?

Avoid alcohol completely. It increases your risk of lactic acidosis (dangerous acid buildup in blood) and may lower your blood sugar to dangerous levels.

What should I do if I miss a dose?

Take it as soon as you remember. If it's nearly time for your next dose, skip the missed dose. Never take a double dose to make up for a forgotten one.

Will this medicine affect my kidneys?

Yes, it can affect kidney function. Your doctor will check your kidneys before starting treatment and regularly thereafter. Drink plenty of water while taking this medicine.

What precautions should I take before surgery?

Inform your surgeon you're taking this medicine. It must be stopped at least 48 hours before planned surgery involving contrast dyes and resumed only after kidney function tests.

Can I take this medicine during pregnancy?

This medicine is generally not recommended during pregnancy, especially in the second and third trimesters. Consult your doctor about alternative diabetes management options if planning a pregnancy.

Last Updated On 24 Sep. 2025 | 8:11AM (IST)

Certified Content

Written by

Ashmita Borgohain

Medical Content Writer | 14 years

MSc (Applied Genetics)

Reviewed by

Dr. Chhavi Rosha

Medical Content Writer | 10 years

BAMS, FMC, MD Resident

Check out Editorial Policy

Manufacturer details

Plot No. 3, 1st Cross Street, Ravichandran Nagar, Thiruvandarkoil, Puducherry – 605102 At: 55/1, 2 & 3, Whirlpool Road, Thiruvandarkoil, Puducherry – 605102

Country of origin: GREECE

Expiry on or after: January 2027

In case of any issues, contact us:

support@truemeds.in|09240250346

Address: 6th floor, Urmi Corporate Park Solaris, Saki Vihar Road, Andheri East, Mumbai 400071

References

Metformin: Uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB00331
DailyMed - METFORMIN ER 500 MG tablet METFORMIN ER 750 MG tablet. (n.d.). https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=b857eccf-b9ff-45ba-8241-f47f5caada2a
Metformin: MedlinePlus drug information. (n.d.). https://medlineplus.gov/druginfo/meds/a696005.html
Fala, L. (2015, March 1). Jardiance (Empagliflozin), an SGLT2 Inhibitor, Receives FDA Approval for the Treatment of Patients with Type 2 Diabetes. PubMed Central (PMC). https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4665046/
Empagliflozin: MedlinePlus Drug Information. (n.d.). https://medlineplus.gov/druginfo/meds/a614043.html
Empagliflozin: Uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB09038

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We, at Truemeds make a diligent attempt to deliver accurate, expert- drafted and thoroughly reviewed medicine related information to our consumers. However, it should, by no means, be considered a substitute for prescription from a certified doctor or a trustworthy doctor-patient relationship. In fact we detest any form of self medication without expert advice. The sole purpose of the information on our portal is to educate our consumers, which helps improve the communication between a doctor and a patient. The information by no means is complete in its entirety and should not be used to diagnose or treat any medical condition. No amount of information can replace the experience and expertise of a doctor, therefore his/her advice always holds priority and should be followed appropriately.

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