Dapalive M 5/500 MG Tablet 10

Allysia Lifesciences Pvt Ltd

Strip of 10 Units

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Composition

Dapagliflozin (5 Mg) + Metformin (500 Mg)

Dapalive M 5/500 MG Tablet 10 is used to improve blood sugar control in adults with type 2 diabetes mellitus. It is a combination medicine that belongs to a class of medications that includes sodium-glucose co-transporter 2 (SGLT2) inhibitors and biguanide antidiabetic agents.

In addition to managing blood sugar levels, this medicine can also reduce the risk of hospitalisation for heart failure in adults with type 2 diabetes who have established cardiovascular disease or multiple cardiovascular risk factors. This dual benefit makes it particularly useful for diabetic patients with heart concerns.

This medicine should be taken orally as directed by your doctor, typically with meals. Before starting this medicine, inform your doctor about any pre-existing conditions you may have, especially kidney problems, or any other medicines you are currently taking. If you notice any side effects while taking this medicine, notify your doctor promptly. Continue taking the medicine for the full duration prescribed by your doctor for optimal results.

Dapalive M 5/500 MG Tablet 10 is used for the following:

Controlling blood sugar in type 2 diabetes
Improving glycaemic control alongside diet and exercise
Reducing risk of hospitalisation for heart failure
Managing cardiovascular risks in diabetic patients
Supporting blood sugar control when single medicines aren't enough
Decreasing glucose production in the liver
Enhancing insulin sensitivity in body tissues
Promoting urinary glucose excretion
Lowering renal threshold for glucose
Complementing lifestyle changes in diabetes management

Take this tablet daily with meals.
Swallow the tablet whole with a full glass of water.
Do not crush, break or chew the tablet.
Maintain good fluid intake throughout the day while taking this medicine.
Store in a cool, dry place away from direct sunlight.
If you have concerns about how to take this medicine, consult your doctor.

Dapalive M 5/500 MG Tablet 10 is taken orally.

Dapalive M 5/500 MG Tablet 10 may have the following common side effects:

Female genital mycotic infections: These are fungal infections affecting the genital area in women.
Urinary tract infections
Diarrhoea
Headache
Nausea
Back pain
Nasopharyngitis: This refers to inflammation of the nose and throat, commonly known as a common cold.
Hypoglycaemia: This is when your blood sugar drops too low, which may cause shakiness, sweating, confusion, or dizziness.

Managing the Side Effects:

Most side effects are temporary and generally harmless, which resolve on discontinuing the use of Dapalive M 5/500 MG Tablet 10. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

Nausea: Taking Dapalive M 5/500 MG Tablet 10 with meals can help reduce feelings of nausea.
Diarrhoea: Try taking this medicine with food to lessen this side effect.

Dapalive M 5/500 MG Tablet 10 contains two active ingredients:

Dapagliflozin (5 mg): This component works by inhibiting sodium-glucose co-transporter 2 (SGLT2) in your kidneys. SGLT2 is a protein that helps your body reabsorb glucose from your urine back into your bloodstream. By blocking this protein, dapagliflozin causes more glucose to be removed from your body through urine, lowering your blood sugar levels.
Metformin (500 mg): As a biguanide medication, metformin works in three main ways to control blood sugar. It decreases glucose production in your liver, reduces glucose absorption from your intestines, and improves how your body responds to insulin, helping your cells take up glucose more effectively from your bloodstream.

Pregnancy

Doctor consultation is advised while taking Dapalive M 5/500 MG Tablet 10 if you are pregnant. This medicine may pose potential risks to the developing baby, especially during the second and third trimesters.

Breastfeeding

Dapalive M 5/500 MG Tablet 10 is contraindicated during breastfeeding. If you are currently breastfeeding or planning to breastfeed, consult your doctor to understand the potential risks and to discuss alternative options for managing your diabetes.

Alcohol

Avoid drinking alcohol while taking Dapalive M 5/500 MG Tablet 10. Alcohol can increase your risk of developing lactic acidosis, a rare but serious condition that can be life-threatening. This happens because both alcohol and metformin (one of the ingredients) affect how your body processes lactic acid.

Liver

Doctor consultation is advised while taking Dapalive M 5/500 MG Tablet 10 if you have liver problems. While this medicine doesn't directly affect the liver, your doctor should monitor your liver function regularly, especially if you have existing liver conditions.

Kidney

Dapalive M 5/500 MG Tablet 10 is contraindicated if you have severe kidney problems. This medicine should not be used if your kidney function is significantly reduced (eGFR below 45 ml/min/1.73 m²). Your doctor will need to check your kidney function before and during treatment.

Using Machines & Driving

You may continue driving and operating machinery while taking Dapalive M 5/500 MG Tablet 10. However, if you experience dizziness or low blood sugar (hypoglycaemia), avoid these activities until you feel better.

Allergy

Avoid taking Dapalive M 5/500 MG Tablet 10 if you have had allergic reactions to dapagliflozin, metformin, or any other ingredients in this medicine. If you develop rash, swelling, or difficulty breathing after taking this medicine, seek medical help immediately.

Children

Doctor consultation is advised regarding the use of Dapalive M 5/500 MG Tablet 10 in children and adolescents under 18 years of age. The safety and effectiveness of this medicine have not been well established for younger patients.

Older Patients

Older patients should take Dapalive M 5/500 MG Tablet 10 under medical supervision as they may be more susceptible to side effects, particularly those related to reduced blood volume. If you are over 65 years of age, your doctor will likely monitor your kidney function more frequently.

Drug-Drug Interactions

Dapalive M 5/500 MG Tablet 10 interacts with the following medicines:

Carbonic anhydrase inhibitors: Medicines like acetazolamide and topiramate may increase the risk of lactic acidosis when taken with Dapalive M 5/500 MG Tablet 10.
Antacids: Medications such as cimetidine can increase metformin levels in your blood, potentially raising the risk of side effects.
Insulin or insulin secretagogues: When Dapalive M 5/500 MG Tablet 10 is taken with insulin or medicines like glimepiride or gliclazide, it may increase the risk of hypoglycaemia (low blood sugar).

Drug-Disease Interactions

Dapalive M 5/500 MG Tablet 10 interacts with the following diseases:

Kidney disease: Patients with severe kidney impairment (eGFR below 30 mL/min/1.73 m²) should not take this medicine as it increases risk of lactic acidosis.
Metabolic acidosis: Dapalive M 5/500 MG Tablet 10 should not be used in patients with metabolic acidosis, including diabetic ketoacidosis, as it may worsen the condition.
Liver disease: Doctor consultation is needed in patients with liver problems as it may increase the risk of lactic acidosis.

Daily Dose

The daily dose of Dapalive M 5/500 MG Tablet 10 should be taken as prescribed by your doctor. The dosage may vary based on your blood sugar control and kidney function. It's important to follow the prescribed dosage and not exceed it without consulting your doctor.

Over Dose

An overdose of Dapalive M 5/500 MG Tablet 10 may cause symptoms like excessive urination, dehydration, stomach discomfort, nausea, and low blood sugar. If you suspect an overdose, contact your doctor or visit the nearest hospital for proper guidance.

Missed Dose

If you forget to take Dapalive M 5/500 MG Tablet 10, take it as soon as you remember. If it's nearly time for your next dose, skip the missed one and continue with your regular schedule. Never double the dose to make up for a missed one.

Store Dapalive M 5/500 MG Tablet 10 below 30°C.
Keep the Tablet in its original packaging, away from moisture.
Store in a cool, dry place away from direct sunlight.
Keep out of sight and reach of children.
Do not use this medicine after the expiry date printed on the package.

Monitor your carbohydrate intake and choose complex carbohydrates (like whole grains) over simple sugars to help maintain stable blood glucose levels.
Engage in regular physical activity (at least 30 minutes of moderate exercise most days) to improve your body's insulin sensitivity and help control your blood sugar.

Fact Box

Available Dosage Types	Tablet
Habit Forming	No
Ailment	Type 2 Diabetes, Hyperglycaemia
Drug Category	SGLT2 Inhibitor + Biguanide
Therapeutic Category	Antidiabetic

What is Dapalive M 5/500 MG Tablet 10 used for?

Dapalive M 5/500 MG Tablet 10 is used to improve blood sugar control in adults with type 2 diabetes. It works alongside proper diet and exercise as part of a complete diabetes management plan.

How does Dapalive M 5/500 MG Tablet 10 work in the body?

It contains two medicines that work differently. Dapagliflozin helps your kidneys remove sugar through urine, while metformin reduces sugar production in your liver and improves insulin effectiveness.

Can Dapalive M 5/500 MG Tablet 10 help with heart problems?

One component (dapagliflozin) may reduce the risk of hospital stays due to heart failure in adults with type 2 diabetes who have heart disease or multiple risk factors.

What are the common side effects of Dapalive M 5/500 MG Tablet 10?

Common side effects include genital yeast infections, throat infections, urinary tract infections, diarrhoea, headache, nausea, and back pain. Most are mild and temporary.

Should I stop taking Dapalive M 5/500 MG Tablet 10 if I feel sick?

Avoid to stop taking this medicine without consulting your doctor. However, if you experience severe symptoms like extreme tiredness, difficulty breathing, or stomach pain, seek medical help immediately.

Can I drink alcohol while taking Dapalive M 5/500 MG Tablet 10?

You should avoid excessive alcohol consumption while taking Dapalive M 5/500 MG Tablet 10. Alcohol can increase your risk of low blood sugar and a rare but serious condition called lactic acidosis.

How should I store Dapalive M 5/500 MG Tablet 10?

Store Dapalive M 5/500 MG Tablet 10 at room temperature (below 30°C) in a dry place. Keep it in its original packaging and out of reach of children.

Last Updated On 04 Jun. 2025 | 6:52AM (IST)

Certified Content

Written by

Ashmita Borgohain

Medical Content Writer | 12 years

MSc (Applied Genetics)

Reviewed by

Dr. Chhavi Rosha

Medical Content Writer | 9 years

BAMS, FMC, MD Resident

Check out Editorial Policy

Manufacturer details

M-50 A Ground Floor, Kalkaji,New Delhi – 110019,India

Country of origin: INDIA

Expiry on or after: December 2025

In case of any issues, contact us:

support@truemeds.in|08069808861

Address: 6th floor, Urmi Corporate Park Solaris, Saki Vihar Road, Andheri East, Mumbai 400071

References

HIGHLIGHTS OF PRESCRIBING INFORMATION. (2014). [Press-release]. XIGDUO XR. https://www.accessdata.fda.gov/drugsatfda_docs/label/2017/205649s008lbl.pdf
Unknown. (2022). GLUCOPHAGE. https://www.accessdata.fda.gov/drugsatfda_docs/label/2017/020357s037s039,021202s021s023lbl.pdf
AstraZeneca. (2014). HIGHLIGHTS OF PRESCRIBING INFORMATION [Press release]. https://www.accessdata.fda.gov/drugsatfda_docs/label/2020/202293s020lbl.pdf
Metformin: Uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB00331
Dapagliflozin: Uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB06292
Bailey, C. J., Gross, J. L., Hennicken, D., Iqbal, N., Mansfield, T. A., & List, J. F. (2013). Dapagliflozin add-on to metformin in type 2 diabetes inadequately controlled with metformin: a randomized, double-blind, placebo-controlled 102-week trial. BMC Medicine, 11(1). https://doi.org/10.1186/1741-7015-11-43

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Disclaimer

We, at Truemeds make a diligent attempt to deliver accurate, expert- drafted and thoroughly reviewed medicine related information to our consumers. However, it should, by no means, be considered a substitute for prescription from a certified doctor or a trustworthy doctor-patient relationship. In fact we detest any form of self medication without expert advice. The sole purpose of the information on our portal is to educate our consumers, which helps improve the communication between a doctor and a patient. The information by no means is complete in its entirety and should not be used to diagnose or treat any medical condition. No amount of information can replace the experience and expertise of a doctor, therefore his/her advice always holds priority and should be followed appropriately.

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