Artiflo 1 Tablet 10

Zuventus Healthcare Ltd

Strip of 10 Units

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MRP ~~₹87.9~~

₹70.32

₹8.79/Units

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Composition

Nicoumalone (1 Mg)

Strength:

3 MG 2 MG 4 MG 1 MG

Artiflo 1 Tablet 10 is used to prevent and treat harmful blood clots that can form in various parts of the body. It belongs to a class of medicines known as anticoagulants that help prevent blood from clotting too easily.

In addition to its primary use, this medicine can also help reduce the risk of stroke in people with certain heart conditions. It may be used as additional therapy for managing coronary occlusion (blockage of heart blood vessels) and transient cerebral ischaemic attacks (temporary reduction of blood flow to the brain).

Before starting this medicine, inform your doctor about any pre-existing medical conditions or ongoing medications you might be taking. If you notice any unusual bleeding or bruising while taking this medicine, notify your doctor immediately. Continue taking the medicine for the full duration prescribed by your doctor for optimal results.

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Artiflo 1 Tablet 10 is used for the following:

Prevention of deep vein thrombosis
Treatment of blood clots in leg veins
Prevention of pulmonary embolism
Reducing stroke risk
Managing harmful blood clot formation
Prevention of blood clots after heart conditions
Management of coronary occlusion
Prevention of transient cerebral ischemic attacks

Follow these instructions while taking Artiflo 1 Tablet 10:

Swallow the tablet whole with a glass of water.
Do not crush, break or chew the tablet.
Take this medicine at the same time each day.
You can take this medicine with or without food, as prescribed by your doctor.
Never stop taking this medicine suddenly without consulting your doctor.

Artiflo 1 Tablet 10 is taken orally.

Artiflo 1 Tablet 10 may have the following common side effects:

Unusual bruising
Bleeding from gums or nose
Blood in urine or tarry stool
Hair loss
Skin necrosis: This refers to the death of skin tissue, which might appear as darkened, painful areas on your skin.
Allergic reactions: You might experience rash, itching, or swelling, particularly of the face, tongue, or throat.

Managing the Side Effects:

Most side effects are temporary and generally harmless, which resolve on discontinuing the use of Artiflo 1 Tablet 10. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

Here are some general guidelines for managing common side effects:

Unusual bruising: Taking this medicine at the same time each day helps maintain consistent blood levels and may reduce this side effect.

Artiflo 1 Tablet 10 contains nicoumalone (1 mg), which works on the body as follows:

Vitamin K antagonism: Nicoumalone blocks the action of vitamin K in your liver, which is essential for the production of certain clotting factors.
Inhibits clotting factors: It specifically reduces the production of clotting factors II, VII, IX, and X, which are proteins that help blood to clot.
Prevents new clot formation: By decreasing these clotting factors, the medicine helps prevent new blood clots from forming in your blood vessels.
Prevents clot growth: It stops existing blood clots from becoming larger, though it does not dissolve clots that have already formed.

Pregnancy

Artiflo 1 Tablet 10 is contraindicated during pregnancy. If you are pregnant or planning to conceive, make sure to discuss this with your doctor before starting this medicine, as it may cause harm to the developing baby.

Breastfeeding

Caution is advised while taking Artiflo 1 Tablet 10 if you are breastfeeding. It is best to consult your doctor before taking this medicine.

Alcohol

You should avoid or limit alcohol consumption while taking Artiflo 1 Tablet 10. Alcohol can increase the risk of bleeding, which is already a concern with this medicine. Your doctor may advise you on safe limits.

Liver

Caution is advised while taking Artiflo 1 Tablet 10 in case of mild to moderate liver impairment. It is not recommended for severe liver diseases. If you have liver problems, discuss them with your doctor before starting Artiflo 1 Tablet 10. This medicine may affect liver function.

Kidney

Caution is advised before using Artiflo 1 Tablet 10 if you have a history of any kidney problems. It is a good idea to consult your doctor before taking this medicine.

Using Machines & Driving

You can usually drive and operate machines while taking Artiflo 1 Tablet 10. However, if you experience dizziness or any unusual symptoms, avoid these activities until you feel better.

Allergy

If you have ever had an allergic reaction to nicoumalone or similar medicines, tell your doctor before taking Artiflo 1 Tablet 10. Signs of an allergic reaction may include skin rash, itching, or breathing problems.

Children

Caution is advised while giving Artiflo 1 Tablet 10 to children under 18 years of age. Always consult your doctor before giving any medicine to a child.

Older Patients

Older patients should take Artiflo 1 Tablet 10 under medical supervision, as they may be more susceptible to its side effects. Caution is advised if patients are above 70 years of age. Older patients might also have liver and kidney issues and might be on other medication. Your doctor will guide you based on your health status.

Drug-Drug Interactions

Artiflo 1 Tablet 10 interacts with the following medicines:

Anticoagulants and antiplatelets: Medicines like heparin and aspirin can increase the risk of bleeding when taken with Artiflo 1 Tablet 10.
Antibiotics: Certain antibiotics, such as erythromycin and ciprofloxacin, can increase the effect of Artiflo 1 Tablet 10, potentially leading to bleeding complications.
Antifungals: Medicines like fluconazole and miconazole may enhance the anticoagulant effect of Artiflo 1 Tablet 10, requiring dose adjustments.
Non-steroidal anti-inflammatory drugs: NSAIDs such as ibuprofen and diclofenac can increase the risk of gastrointestinal bleeding when combined with Artiflo 1 Tablet 10.
Antidepressants: Selective serotonin reuptake inhibitors (SSRIs) may increase the risk of bleeding when taken with Artiflo 1 Tablet 10.

Drug-Food Interactions

Artiflo 1 Tablet 10 interacts with the following foods:

Cranberry juice: This may increase the anticoagulant effect, potentially raising bleeding risk.

Drug-Disease Interactions

Artiflo 1 Tablet 10 interacts with the following diseases:

Liver disease: Patients with liver problems may experience enhanced anticoagulant effects as the liver metabolises nicoumalone.
Kidney disease: Severe kidney impairment may alter the way Artiflo 1 Tablet 10 works in your body.
Bleeding disorders: This medicine can worsen existing bleeding conditions and increase bleeding risk.

Daily Dose

The daily dose of Artiflo 1 Tablet 10 should be taken as prescribed by your doctor. The dosage may change based on individual factors such as your condition's severity and response to treatment. It is important to follow the prescribed dosage without exceeding it.

Over Dose

Taking too much nicoumalone may cause unusual bleeding or bruising. You might notice blood in your urine, stool, or when coughing. If you experience a severe headache or stomach pain, consult your doctor promptly.

Missed Dose

If you forget to take Artiflo 1 Tablet 10, take it as soon as you remember. If it's almost time for your next dose, skip the missed one and resume your regular schedule. Never take a double dose to make up for a missed one.

Follow these instructions while storing Artiflo 1 Tablet 10:

Store Artiflo 1 Tablet 10 at room temperature (not exceeding 30°C) in a dry place.
Keep the medicine protected from direct light and moisture.
Store in the original packaging until ready to use.
Always keep this medicine out of sight and reach of children.
Check the expiry date before use and do not take expired tablets.

Monitor your vitamin K intake from foods like green leafy vegetables (spinach, kale), as these can affect how well nicoumalone works in preventing blood clots.
Limit or avoid alcohol consumption while taking this medicine, as alcohol can increase your risk of bleeding complications.

Fact Box

Available Dosage Types	Tablet
Habit Forming	No
Ailment	Blood clots, DVT, Stroke prevention
Drug Category	Vitamin K antagonist
Therapeutic Category	Anticoagulant

How long does it take for Artiflo 1 Tablet 10 to start working?

Nicoumalone typically takes 2-3 days to reach its full blood-thinning effect. Sometimes your doctor may prescribe a faster-acting medicine alongside it initially.

Can I take Artiflo 1 Tablet 10 with food?

You can take this medicine with or without food, as prescribed by your doctor. However, be consistent in your approach—either always take it with food or always without.

What should I do if I miss a dose?

Take it as soon as you remember. If it's nearly time for your next dose, skip the missed one and continue with your regular schedule. Never take a double dose.

How often will I need blood tests while taking this medicine?

Initially, you may need tests weekly or fortnightly or as suggested by your doctor. Once your blood clotting levels (INR) stabilise, your doctor may reduce testing to monthly or less often.

What are the most important side effects to watch for?

Watch for unusual bleeding or bruising, blood in urine or stool, coughing up blood, or severe headaches. Contact your doctor immediately if these occur.

Can I drink alcohol while taking Artiflo 1 Tablet 10?

You should avoid or strictly limit alcohol while taking nicoumalone, as it can increase your risk of bleeding. Consult your doctor about safe limits.

Should I tell other doctors or dentists that I take this medicine?

Always inform any doctor or dentist about taking nicoumalone before procedures or surgery. This medicine affects blood clotting and may require special precautions.

Last Updated On 22 May. 2025 | 11:39AM (IST)

Certified Content

Written by

Ashmita Borgohain

Medical Content Writer | 12 years

MSc (Applied Genetics)

Reviewed by

Dr. Divya Chauhan

Medical Content Writer & Reviewer | 7 years

BAMS, APG, PG

Check out Editorial Policy

Manufacturer details

Oberoi Garden Estate, Sakinaka, Andheri East, Chandivali Rd, Powai, Mumbai, Maharashtra 400072

Country of origin: INDIA

Expiry on or after: October 2025

In case of any issues, contact us:

support@truemeds.in|08069808861

Address: 6th floor, Urmi Corporate Park Solaris, Saki Vihar Road, Andheri East, Mumbai 400071

References

Acenocoumarol: Uses, Interactions, Mechanism of Action https://go.drugbank.com/drugs/DB01418
National Center for Biotechnology Information (2025). PubChem Compound Summary for CID 54676537, Acenocoumarol. Retrieved May 14, 2025 from https://pubchem.ncbi.nlm.nih.gov/compound/Acenocoumarol.
BRAFIELD A. J. (1959). Nicoumalone: a new anticoagulant. British medical journal, 1(5131), 1211–1213. https://doi.org/10.1136/bmj.1.5131.1211
Acenocoumarol (N.d.). Retrieved May 14, 2025, from https://www.sciencedirect.com/topics/neuroscience/acenocoumarol

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Disclaimer

We, at Truemeds make a diligent attempt to deliver accurate, expert- drafted and thoroughly reviewed medicine related information to our consumers. However, it should, by no means, be considered a substitute for prescription from a certified doctor or a trustworthy doctor-patient relationship. In fact we detest any form of self medication without expert advice. The sole purpose of the information on our portal is to educate our consumers, which helps improve the communication between a doctor and a patient. The information by no means is complete in its entirety and should not be used to diagnose or treat any medical condition. No amount of information can replace the experience and expertise of a doctor, therefore his/her advice always holds priority and should be followed appropriately.

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Office Unit no. 1, 2, 5, & 7, 6th floor Urmi Corporate Park Solaris, Saki Vihar Rd, Opp. L&T Flyover, New Mhada Colony, Budhia Jadhav Wadi, Mumbai, Maharashtra 400072.

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