Zymurine Tablet 10

Zymurine Tablet 10 is used for the following:

• Helps prevent the body's immune system from attacking and rejecting the newly transplanted kidney

• Manage severe rheumatoid arthritis symptoms when first-line treatments fail to provide adequate relief

Here's how you should take Zymurine Tablet 10:

• Swallow the tablet whole with a glass of water. Chewing or crushing the tablet is not advisable.

• Taking this medicine with food is best, as it can help minimise possible stomach discomfort.

• Do not exceed the dose recommended by your doctor.

• Always consult your doctor before changing how you take this medicine.

Zymurine Tablet 10 is taken orally.

Zymurine Tablet 10 contains azathioprine (50 mg), which operates on your body in a specific manner:

• Inhibition of Purine Synthesis: Azathioprine works by hampering purine synthesis in the body. Purines are necessary for DNA and RNA production. By inhibiting their synthesis, azathioprine suppresses immune responses mediated by T cells.

• Disruption of DNA Synthesis: After being absorbed by the body, azathioprine is converted into 6-mercaptopurine, which then transforms into 6-thioguanine nucleotides. These nucleotides disrupt DNA synthesis and inhibit the growth of fast-dividing cells like T and B lymphocytes, resulting in the suppression of the immune system.

• Store Zymurine Tablet 10 away from direct sunlight and moist environments.

• Keep the packaging tightly closed when not in use to protect it from air and light exposure.

• Always place the medicine out of the reach of children and pets.

• Ensure you use this medicine before its expiry date.

• If you're managing rheumatoid arthritis with Zymurine Tablet 10, incorporate gentle exercise routines into your daily schedule. This can help maintain joint flexibility and reduce stiffness.

• Maintaining a balanced diet low in sodium and fibre is recommended for patients who have undergone kidney transplantation. This supports kidney health and helps manage overall well-being. Always consult your doctor for individual dietary advice.