Winril M2 Forte Tablet 10

Syswin Pharmaceuticals Ltd

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Composition

Glimepiride (2 Mg) + Metformin (1000 Mg)

Winril M2 Forte Tablet 10 is a specialized medication utilized for the management of type 2 diabetes mellitus in adults. This "Forte" (higher strength) combination is prescribed when diet, exercise, and single-agent therapies are not enough to reach target blood glucose levels. It works by improving the way your body handles insulin and reducing the amount of sugar produced by the liver, leading to more stable blood sugar levels throughout the day.

Proper glycemic control is essential for preventing the serious long-term complications of diabetes, such as vision loss or kidney failure. This medication should always be taken as part of a comprehensive treatment plan that includes a controlled diet and regular physical activity. Inform your doctor of your complete medical history before starting, and ensure you follow up with regular blood tests to monitor your progress and ensure the treatment is working effectively.

Winril M2 Forte Tablet 10 is used for the following:

Improving blood sugar control in adults with type 2 diabetes mellitus.
Helping to manage blood glucose levels when diet and exercise alone are insufficient.
Ensuring better glycaemic control when single-agent therapy doesn't provide the desired results.
Assisting in the decrease of intestinal glucose absorption.
Enhancing the function of insulin in your body.

Swallow the tablet whole with a glass of water during meals.
Avoid chewing or crushing the tablet.
Follow the dosage and timing prescribed by your doctor.
Never alter your medication regime without consulting your doctor first.

Winril M2 Forte Tablet 10 is taken orally.

While taking Winril M2 Forte Tablet 10, you may experience several common side effects. These include:

Nausea
Vomiting
Diarrhoea
Abdominal pain
Weight gain
Low blood sugar levels

Management Of Side Effects:

Most side effects are temporary and generally harmless, which resolve on discontinuing the use of Winril M2 Forte Tablet 10. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

Here's how to manage some common side effects:

Hypoglycaemia: Keep some form of quick sugar handy, like fruit juice or regular soda, to swiftly manage a low blood sugar episode.
Diarrhoea: Taking Winril M2 Forte Tablet 10 with meals can help reduce this effect.

Winril M2 Forte Tablet 10 contains two active ingredients that work together to control blood glucose levels:

Glimepiride (2 mg): This sulfonylurea class medicine binds itself to specific receptors on the pancreatic beta cells. This binding results in these cells secreting more insulin, which reduces blood glucose levels. Moreover, glimepiride also enhances the sensitivity of peripheral tissues to insulin and may help reduce glucose production in the liver.
Metformin (1000 mg): Falling under the biguanide class of medicines, metformin performs a trio of actions to control high blood sugar. It reduces glucose production in your liver, lowers glucose absorption from your intestines after meals, and improves insulin sensitivity. The increased insulin sensitivity allows your body to utilise the glucose present in your bloodstream better.

Pregnancy

Caution is advised while taking Winril M2 Forte Tablet 10 if you are pregnant. It is best to consult your doctor before taking this medicine.

Breastfeeding

Breastfeeding women should consult their doctor before using Winril M2 Forte Tablet 10, to understand potential risks or benefits to the mother and the baby.

Alcohol

Avoid excessive alcohol intake while taking Winril M2 Forte Tablet 10, as alcohol can increase the risk of lactic acidosis, a side effect of metformin.

Liver

If you have liver problems, discuss them with your doctor before starting Winril M2 Forte Tablet 10. This medicine may affect liver function and should be used cautiously in case of hepatic dysfunction.

Kidney

Winril M2 Forte Tablet 10 should be used cautiously in patients with kidney issues. Regular monitoring of renal function is advised during long-term therapy.

Use In Driving And Operating Machinery

No specific precaution is needed regarding the use of Winril M2 Forte Tablet 10 while driving or operating machinery. However, if you experience side effects like dizziness or fatigue, it would be wise to avoid such activities until you feel better.

Allergy

Do not take Winril M2 Forte Tablet 10 if you are allergic to glimepiride, metformin, or any other ingredients in the formulation.

Children

Winril M2 Forte Tablet 10 is not recommended for use in children under 18. If a child needs this medication, always consult a doctor first.

Older Patients

Older patients taking Winril M2 Forte Tablet 10 should do so under medical supervision, as they might be more susceptible to its side effects. Your doctor will guide you based on your health status.

Drug-Drug Interactions

Winril M2 Forte Tablet 10 may interact with the following medicines:

Antidiabetic Medication: Insulin can intensify the blood sugar-lowering effect of Winril M2 Forte Tablet 10, potentially leading to hypoglycemia (low blood sugar).
Diuretics: Medications such as hydrochlorothiazide and chlorthalidone may weaken the hypoglycaemic effect (blood sugar reduction) of Winril M2 Forte Tablet 10, potentially leading to higher blood sugar levels.
Sulfonamides: Medications like trimethoprim can enhance the hypoglycaemic effect of Winril M2 Forte Tablet 10.
Cationic medicines: Medications like cimetidine and ranitidine that are eliminated by renal tubular secretion may interact with metformin in Winril M2 Forte Tablet 10, increasing the risk of lactic acidosis.

Drug-Food Interactions

Most foods do not significantly interact with Winril M2 Forte Tablet 10.

Drug-Disease Interactions

Winril M2 Forte Tablet 10 may interact with the following diseases:

Liver Disease: This medicine should be used cautiously in patients with liver problems as its effectiveness could be affected.
Kidney Disease: Patients with kidney disease should be cautious as this medicine might exacerbate their condition.
Heart Problems: Individuals with congestive heart failure should use Winril M2 Forte Tablet 10 carefully as it could worsen their condition.

Daily Dose

Take the daily recommended dose of Winril M2 Forte Tablet 10 as your doctor prescribes. The dose may vary based on the severity of your condition and your response. It's crucial to adhere to this dosage and not exceed it without consulting your doctor. For further details regarding dosage instructions, please read the package insert.

Over Dose

In case of an accidental overdose of Winril M2 Forte Tablet 10, you might experience common side effects like nausea, vomiting, and diarrhoea more intensely. If these symptoms persist or worsen, seek medical attention immediately.

Missed Dose

If you forget to take Winril M2 Forte Tablet 10 at the scheduled time, take it as soon as you remember. However, if it's nearly time for your next dose, skip the missed one and continue with your regular schedule. Never adjust your dosage without consulting your doctor.

Store in a cool, dry and dark place.
Protect the medicine from light and moisture.
Ensure the tablet is safely out of children's reach.
Use it before the expiration date printed on the product.

It's important to keep yourself active. Regular exercise can help your body use insulin better, which is crucial when managing type 2 diabetes with Winril M2 Forte Tablet 10.
Opt for a diet rich in whole grains, fruits, vegetables, and lean proteins. Avoid foods high in sugar that can spike blood glucose levels.

Fact Box

Dosage Forms Available	Tablet
Habit Forming	No
Ailment	Type 2 Diabetes Mellitus
Drug Category	Sulfonylurea, Biguanide
Therapeutic Category	Antidiabetic

What is the purpose of Winril M2 Forte Tablet 10?

It is used to manage blood sugar levels in adults with type 2 diabetes, when diet and exercise alone aren't enough.

How does Winril M2 Forte Tablet 10 work?

It contains two medicines which work together to reduce blood sugar; one increases insulin secretion, and the other reduces sugar production and absorption.

How should I take Winril M2 Forte Tablet 10?

You should take it orally, typically with meals. Always follow your doctor's instructions on how and when to take it.

Are there any side effects of Winril M2 Forte Tablet 10?

Yes, you may experience common side effects like low blood sugar, nausea, vomiting, diarrhoea, stomach pain, and weight gain. If these symptoms persist or get worse, consult your doctor immediately.

Can I consume alcohol while taking Winril M2 Forte Tablet 10?

It's best to avoid alcohol as it can increase the risk of low blood sugar and lactic acidosis thus leading to other symptoms.

Is it safe to use during pregnancy or while breastfeeding?

The medicine should only be used if the benefits outweigh the potential risks. Always discuss this with your doctor before starting this medication.

What should I do if I miss a dose of Winril M2 Forte Tablet 10?

Take the missed dose with food as soon as you remember. If it's close to the next dose time, skip the missed one.

Last Updated On 18 Mar. 2026 | 6:28PM (IST)

Certified Content

Written by

Ashmita Borgohain

Medical Content Writer | 13 years

MSc (Applied Genetics)

Reviewed by

Dr. Divya Chauhan

Medical Content Writer & Reviewer | 8 years

BAMS, APG, PG

Check out Editorial Policy

Manufacturer details

No. 3919, 1 St Cross, Girinagar 4 Th Phase, Bangalore Bangalore Ka 560085 In.

Country of origin: INDIA

Expiry on or after: July 2026

In case of any issues, contact us:

support@truemeds.in|09240250346

Address: 6th floor, Urmi Corporate Park Solaris, Saki Vihar Road, Andheri East, Mumbai 400071

References

Glimepiride. (n.d.). Medlineplus.Gov. Retrieved August 20, 2024, from
https://medlineplus.gov/druginfo/meds/a696016.html
Metformin. (n.d.). Medlineplus.Gov. Retrieved August 20, 2024, from https://medlineplus.gov/druginfo/meds/a696005.html
Glimepiride: Uses, Interactions, Mechanism of Action | DrugBank Online. (n.d.-d). DrugBank. https://go.drugbank.com/drugs/DB00222
Glimepiride. (N.d.). Fda.Gov. Retrieved August 20, 2024, from https://www.accessdata.fda.gov/drugsatfda_docs/psg/Glimepiride_tab_20496_RC11-04.pdf
PubChem. (n.d.). Glimepiride. Nih.Gov. Retrieved August 20, 2024, from
https://pubchem.ncbi.nlm.nih.gov/compound/Glimepiride.
Glumetza ™, 500 mg (metformin hydrochloride extended-release tablet)(N.d.). Fda.Gov. Retrieved August 20, 2024, from https://www.accessdata.fda.gov/drugsatfda_docs/label/2006/021748s002lbl.pdf

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Disclaimer

We, at Truemeds make a diligent attempt to deliver accurate, expert- drafted and thoroughly reviewed medicine related information to our consumers. However, it should, by no means, be considered a substitute for prescription from a certified doctor or a trustworthy doctor-patient relationship. In fact we detest any form of self medication without expert advice. The sole purpose of the information on our portal is to educate our consumers, which helps improve the communication between a doctor and a patient. The information by no means is complete in its entirety and should not be used to diagnose or treat any medical condition. No amount of information can replace the experience and expertise of a doctor, therefore his/her advice always holds priority and should be followed appropriately.

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Registered Office Address

Intellihealth Solutions Private Limited

Unit-301 & 304, Lightbridge Tunga Village, Saki Vihar Rd, Chandivali, Powai, Mumbai, Maharashtra, India, 400072.

CIN: U62099MH2019PTC320566

Telephone:09240250346

Grievance Officer

Name: Kishor Kumar

Email: grievance-officer@truemeds.in

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