Triplixam 4mg/1.25mg/5mg Tablet 10

Servier India Private Limited

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Old MRP ₹256.22

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Composition

Amlodipine (5 Mg) + Indapamide (1.25 Mg) + Perindopril (4 Mg)

Triplixam 4mg/1.25mg/5mg Tablet is a combination medicine used to treat high blood pressure (hypertension). It belongs to the antihypertensive class of medications.

In addition to its primary use, this medicine helps to relax your blood vessels, remove excess salt and water from your body, and improve blood flow. This contributes to a more effective control of your blood pressure, which can't be achieved with the individual components alone.

It's important to take this medicine as directed by your doctor. Before starting, make sure to inform your doctor about any pre-existing conditions or ongoing medications. If you notice any side effects while on this medicine, notify your doctor immediately. For optimal results, continue taking the medicine for the duration prescribed by your doctor.

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Triplixam Tablet is used to treat high blood pressure (hypertension) and to reduce the risk of cardiovascular events like heart attack, stroke, and other heart-related complications. It helps in managing these conditions by combining three active ingredients that work together to regulate blood pressure and improve heart health.

Here are some guidelines to follow while taking Triplixam 4mg/1.25mg/5mg Tablet :

Swallow the tablet whole with a glass of water.
Do not crush or chew the tablet.
Always consult your doctor before adjusting your dosage or stopping the medication.

Triplixam 4mg/1.25mg/5mg Tablet is taken orally.

The use of Triplixam 4mg/1.25mg/5mg Tablet may result in the following side effects:

Headache
Dizziness
Fatigue
Nausea
Diarrhoea
Cough
Peripheral oedema: This refers to swelling of the ankles, feet, or hands due to fluid accumulation.

Managing the Side Effects:

Most side effects are temporary and generally harmless, which resolve upon discontinuing the use of Triplixam 4mg/1.25mg/5mg Tablet. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor. Here are some general guidelines:

Nausea: Try taking Triplixam 4mg/1.25mg/5mg Tablet with food to alleviate this symptom.
Peripheral oedema: If swelling occurs in your ankles, feet, or hands after taking the medicine, you may want to try taking it at bedtime.

Triplixam 4mg/1.25mg/5mg Tablet contains three active ingredients:

Perindopril (4 mg): This angiotensin-converting enzyme (ACE) inhibitor prevents the formation of angiotensin II, a substance that narrows your blood vessels. This allows your blood vessels to relax and widen, which lowers your blood pressure and improves blood flow.
Indapamide (1.25 mg): This thiazide-like diuretic increases the excretion of sodium and water by your kidneys. This action reduces blood volume and pressure.
Amlodipine (5 mg): This calcium channel blocker works by relaxing the smooth muscles in your blood vessel walls. This causes them to widen, which improves blood flow and reduces the workload on your heart.

Pregnancy

Triplixam 4mg/1.25mg/5mg Tablet is contraindicated during pregnancy. If you are pregnant or planning to conceive, make sure to discuss this with your doctor before starting this medicine.

Breastfeeding

Triplixam 4mg/1.25mg/5mg Tablet is not suitable for breastfeeding women. Consult your doctor to understand the potential risks and benefits.

Alcohol

Caution is advised while consuming alcohol during treatment with Triplixam 4mg/1.25mg/5mg Tablet, as it may alter the blood pressure-lowering effects of the medicine. It is best to consult your doctor for advice.

Liver

Caution is advised while taking Triplixam 4mg/1.25mg/5mg Tablet in case of mild to moderate liver impairment. This medicine is contraindicated for severe liver diseases. Discuss any liver problems with your doctor before starting this medication.

Kidney

If you have a history of kidney problems, caution is advised before taking Triplixam 4mg/1.25mg/5mg Tablet. Consult your doctor before using this medicine.

Using Machines & Driving

Triplixam 4mg/1.25mg/5mg Tablet may cause dizziness or fatigue which can affect your ability to drive or operate machinery safely. Do not drive or operate machines until you know how this medicine affects you.

Allergy

If you are allergic to perindopril, indapamide, amlodipine, or any other components of Triplixam 4mg/1.25mg/5mg Tablet, avoid taking this medicine.

Children

Triplixam 4mg/1.25mg/5mg Tablet is not recommended for use in children. Always consult your doctor before giving any medicine to a child.

Older Patients

Older patients should take Triplixam 4mg/1.25mg/5mg Tablet under medical supervision as they may be more susceptible to its side effects. Caution is advised if patients are above the age of 70 years. Your doctor will guide you based on your health status.

Drug-Drug Interactions

Triplixam 4mg/1.25mg/5mg Tablet interacts with the following medicines:

Antihypertensive agents: These medicines, like losartan or metoprolol, may interact with Triplixam 4mg/1.25mg/5mg Tablet increasing the risk of lower-than-normal blood pressure levels.
NSAIDs: Medicines such as ibuprofen and naproxen can reduce the blood pressure-lowering effects of Triplixam.
Antimanic agents: Medicines like lithium when taken with this medication can lead to high lithium levels, causing toxicity.
Cardiac glycoside: Digoxin when used with Triplixam, could heighten digoxin levels in your blood and increase the risk of side effects.
Potassium supplements or potassium-sparing diuretics: If taken together with Triplixam, they might lead to increased potassium levels in your blood.

Drug-Food Interactions

Triplixam 4mg/1.25mg/5mg Tablet has interactions with certain foods:

High-potassium foods: Consuming potassium-rich food like bananas and spinach along with this medicine might increase the risk of high potassium levels in your blood.

Drug-Disease Interactions

Triplixam 4mg/1.25mg/5mg Tablet interacts with the following diseases:

Kidney disease: Patients with kidney issues may face challenges as this medicine can impact kidney function.
Diabetes: Due to its effect on insulin and glucose metabolism, diabetic patients should closely monitor their blood sugar levels when taking this medication.
Gout: This medicine might increase uric acid levels in the body leading to gout attacks.
Heart disease: With its impact on heart rate and blood pressure, it's crucial for patients with heart problems to use this medication under a doctor's supervision.

Daily Dose

The daily dose of Triplixam 4mg/1.25mg/5mg Tablet should be taken as instructed by your doctor. Your dosage may vary based on several factors, including the severity of the condition and response to treatment.

Over Dose

If you take more than the prescribed dosage of Triplixam 4mg/1.25mg/5mg Tablet, it may lead to symptoms like dizziness or fatigue. If these symptoms persist, consult your doctor.

Missed Dose

If you miss a dose of Triplixam 4mg/1.25mg/5mg Tablet, take it as soon as possible. If it's nearly time for the next dose, skip the missed one and continue your schedule.

Store your Triplixam 4mg/1.25mg/5mg Tablet at a cool room temperature, ideally between 15-30°C.
Protect this medicine from light and moisture; keep it in its original, tightly closed container.
Do not forget to place this medicine out of sight and reach of children.
Always check the expiry date on the packaging before use.

Since Triplixam 4mg/1.25mg/5mg Tablet is used to manage hypertension, reducing your salt intake can help control your blood pressure. Opt for low-sodium alternatives when cooking or eating out.
Regular physical activity, such as brisk walking or cycling, can also help lower your blood pressure. Try to incorporate at least 30 minutes of moderate exercise into your daily routine.

Fact Box

Available Dosage Types	Tablet
Habit Forming	No
Ailment	Hypertension
Drug Category	ACE Inhibitor, Thiazide-like Diuretic, Calcium Channel Blocker
Therapeutic Category	Antihypertensive

What is Triplixam 4mg/1.25mg/5mg Tablet used for?

Triplixam 4mg/1.25mg/5mg Tablet is used to manage high blood pressure in adults whose hypertension isn't sufficiently managed by its components.

How does Triplixam 4mg/1.25mg/5mg Tablet work?

Triplixam 4mg/1.25mg/5mg Tablet contains three components that work differently to improving blood flow, removing excess salt and water, and lower blood pressure by relaxing blood vessels.

How should I take Triplixam 4mg/1.25mg/5mg Tablet?

Triplixam 4mg/1.25mg/5mg Tablet should be taken orally. Always follow your doctor's instructions.

What if I miss a dose of Triplixam 4mg/1.25mg/5mg Tablet?

If you miss a dose, take it as soon as you remember. If it's near the time for your next dose, skip the missed one.

What are common side effects of Triplixam 4mg/1.25mg/5mg Tablet?

Common side effects include headache, dizziness, fatigue, nausea, diarrhoea, cough, and swelling of the ankles, feet or hands.

Can I stop taking Triplixam 4mg/1.25mg/5mg Tablet if my blood pressure normalises?

No, you shouldn't stop taking Triplixam 4mg/1.25mg/5mg Tablet without consulting your doctor even if your blood pressure is well-controlled.

Can I take Triplixam 4mg/1.25mg/5mg Tablet during pregnancy?

No, pregnant or breastfeeding women should not take Triplixam 4mg/1.25mg/5mg Tablet without consulting a doctor. Always consult a doctor before starting any medication if you are pregnant or planning to conceive.

Last Updated On 13 May. 2025 | 10:55AM (IST)

Certified Content

Written by

Dr Nikita Lobo

Medical Content Reviewer | 9 years

BDS, MDS

Reviewed by

Dr. Osama Ahmed

Medical Content Writer | 4 years

Bachelor of Dental Surgery

Check out Editorial Policy

Manufacturer details

1703, 17th Floor, Parinee Crescenzo, 'B' Wing, Plot No. 38 & 39 G Block behind MCA, MKC Bandra East, Mumbai 40051

Country of origin: INDIA

Expiry on or after: July 2026

In case of any issues, contact us:

support@truemeds.in|09240250346

Address: 6th floor, Urmi Corporate Park Solaris, Saki Vihar Road, Andheri East, Mumbai 400071

References

NHS. (n.d.). Amlodipine. https://www.nhs.uk/medicines/amlodipine/. Accessed 1 April 2024.
U.S. National Library of Medicine. (n.d.). Amlodipine. https://dailymed.nlm.nih.gov/dailymed/fda/fdaDrugXsl.cfm?setid=0687ed93-4761-4f9c-887d-95309c03f60e&type=display. Accessed 1 April 2024.
MedlinePlus. (n.d.). Amlodipine. https://medlineplus.gov/druginfo/meds/a602017.html. Accessed 1 April 2024.
U.S. Food and Drug Administration. (2007). Covera-HS® (verapamil hydrochloride) Extended-Release Tablets. https://www.accessdata.fda.gov/drugsatfda_docs/label/2007/022026lbl.pdf. Accessed 1 April 2024.
U.S. Food and Drug Administration. (2005). NDA 20-184/S-011 Covera-HS® (verapamil hydrochloride) Extended-Release Tablets. https://www.accessdata.fda.gov/drugsatfda_docs/label/2005/020184s011lbl.pdf. Accessed 1 April 2024.

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Disclaimer

We, at Truemeds make a diligent attempt to deliver accurate, expert- drafted and thoroughly reviewed medicine related information to our consumers. However, it should, by no means, be considered a substitute for prescription from a certified doctor or a trustworthy doctor-patient relationship. In fact we detest any form of self medication without expert advice. The sole purpose of the information on our portal is to educate our consumers, which helps improve the communication between a doctor and a patient. The information by no means is complete in its entirety and should not be used to diagnose or treat any medical condition. No amount of information can replace the experience and expertise of a doctor, therefore his/her advice always holds priority and should be followed appropriately.

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CIN: U62099MH2019PTC320566

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