Rolnox 60 Injection 0.6ml is used to prevent and treat blood clots, including deep vein thrombosis (DVT) and clots in the lungs (pulmonary embolism), and is used in certain heart conditions alongside other treatment.
It contains enoxaparin, a low-molecular-weight heparin (an anticoagulant, or blood thinner). It works by helping to stop clots forming and growing.
It is given by injection under the skin as prescribed. Do not stop it without medical advice, as this can raise the risk of a clot.
Tell your doctor about any bleeding problems, kidney problems or a low platelet count before use. Report unusual bruising, bleeding that will not stop, or black stools.
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Rolnox 60 Injection 0.6Ml
Pre-filled syringe of 0.60 ML
Old MRP ₹550
MRP ₹515.62
₹412.5
₹859.37/ML
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Safe packing and storage
Non returnable productView policy
Prescription required for this medicine
Store in refrigerator or (2° - 8° C) Do Not Freeze
CompositionAbout Rolnox 60 Injection 0.6Ml
Uses of Rolnox 60 Injection 0.6Ml
Rolnox 60 Injection 0.6ml is used to prevent and treat blood clots.
Uses of Rolnox 60 Injection 0.6ml are:
• Clot Prevention: Helps prevent clots after surgery or during illness.
• Clot Treatment: Treats DVT and clots in the lungs.
• Heart Conditions: Used alongside other treatment in certain heart conditions.
Directions for Use of Rolnox 60 Injection 0.6Ml
Administer Rolnox 60 Injection 0.6ml as per the following guidelines:
- Rolnox 60 Injection 0.6ml is administered under the skin, known as subcutaneous injection.
- Always ensure that the injection site is clean and dry prior to administration.
- Strictly follow your doctor's instructions on time and frequency of injections.
Route of Administration
Rolnox 60 Injection 0.6ml is administered subcutaneously, which means it is injected under the skin.
Side Effects of Rolnox 60 Injection 0.6Ml
Rolnox 60 Injection 0.6ml may cause some side effects that are usually mild and go away as your body adjusts to the medicine.
A few common side effects of Rolnox 60 Injection 0.6ml:
• Bleeding: A greater tendency to bruise or bleed; report bleeding that will not stop.
• Injection Site: Pain, redness or bruising where you inject.
• Blood: A temporary fall in platelet count; your doctor may check your blood.
If side effects do not improve or become serious, speak to your doctor right away.
Management Of Side Effects:
Most side effects are temporary and generally harmless, which resolve on discontinuing the use of Rolnox 60 Injection 0.6ml. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor. Managing common side effects:
- Local irritation: Administer Rolnox 60 Injection 0.6ml at different spots each time to reduce irritation.
- Allergic reactions: If you notice signs of an allergic reaction after administering Rolnox 60 Injection 0.6ml, stop the medicine and consult with your doctor immediately.
How Rolnox 60 Injection 0.6Ml Works?
Rolnox 60 Injection 0.6ml contains enoxaparin sodium (60 MG). Here's how it works:
- Potentiates Inhibition of Factor Xa and Thrombin: Enoxaparin sodium enhances the inhibition of Factor Xa and thrombin by antithrombin. These factors play a key role in blood clotting; thus their inhibition aids in preventing clots from forming.
- Little Effect on Platelet Aggregation and Clotting Tests: At recommended doses, enoxaparin sodium does not significantly influence platelet aggregation or global clotting tests such as prothrombin time (PT) and activated partial thromboplastin time (aPTT). This means it can manage blood clotting without significantly affecting other aspects of blood coagulation.
Safety Measures & Warnings
Pregnancy
Caution is advised while administering Rolnox 60 Injection 0.6ml if you are pregnant. It is best to consult your doctor before administering this medicine.
Breastfeeding
Administering of Rolnox 60 Injection 0.6ml while breastfeeding should only be considered if the benefits outweigh the risks. Always consult your doctor before use.
Alcohol
Rolnox 60 Injection 0.6ml does not significantly affect liver function. However, if you have any liver health issues, it is advisable to discuss with your doctor before starting this medicine.
Liver
If you have a history of kidney problems or impaired kidney functions, it is crucial to consult your doctor before using Rolnox 60 Injection 0.6ml. Dosage adjustments may be needed in patients with severe renal impairment.
Kidney
Rolnox 60 Injection 0.6ml does not usually affect your ability to drive or operate machinery. However, if you feel unwell after administering the medicine, avoid such activities until you feel better.
Use In Driving And Operating Machinery
If you are allergic to enoxaparin sodium, heparin, or pork products, do not use Rolnox 60 Injection 0.6ml as it may trigger an allergic reaction.
Allergy
If you are allergic to enoxaparin sodium, heparin, or pork products, do not use Rolnox 60 Injection 0.6ml as it may trigger an allergic reaction.
Children
The safety and effectiveness of Rolnox 60 Injection 0.6ml in children have not been established. Always consult your doctor before giving this medicine to anyone under 18 years of age.
Older Patients
Older patients should administer Rolnox 60 Injection 0.6ml under medical supervision as they may be more susceptible to its side effects. Your doctor will guide you based on your health status and closely monitor for any adverse effects.
Interactions of Rolnox 60 Injection 0.6Ml
Drug-Drug Interactions
Rolnox 60 Injection 0.6ml interacts with the following medicines:
- Anticoagulants: Medications such as warfarin, when used with Rolnox 60 Injection 0.6ml, may increase the risk of bleeding due to their blood-thinning effects.
- Non-Steroidal Anti-Inflammatory Medicines (NSAIDs): Medicines like ibuprofen or naproxen can increase the likeliness of bleeding when taken with Rolnox 60 Injection 0.6ml.
- Thrombolytics and GPIIb/IIIa Antagonists: These medicines, such as alteplase or eptifibatide, can increase the risk of bleeding when administered with Rolnox 60 Injection 0.6ml.
Drug-Food Interactions
There are no known specific food interactions with Rolnox 60 Injection 0.6ml. However, it is advisable to maintain a balanced diet while on medication.
Drug-Disease Interactions
Rolnox 60 Injection 0.6ml interacts with the following diseases:
- Bleeding Disorders: People suffering from haemophilia or other inherited or acquired bleeding conditions should exercise caution as Rolnox 60 Injection 0.6ml could exacerbate their condition.
- Kidney Disease: Those with severe renal impairment may need dosage adjustments for Rolnox 60 Injection 0.6ml to avoid potential complications.
Dosage of Rolnox 60 Injection 0.6Ml
Daily Dose
The daily dose of Rolnox 60 Injection 0.6ml should be administered as directed by your doctor. The dosage may vary based on individual factors such as the severity of your condition and your response to the medication.
Over Dose
In case of accidental overdosage of Rolnox 60 Injection 0.6ml, you might experience symptoms such as increased bleeding. Do not panic but do inform your doctor if you observe any unusual signs or symptoms to ensure appropriate management.
Missed Dose
If you realise that you have missed a dose of Rolnox 60 Injection 0.6ml, administer it as soon as you remember. However, if it is almost time for the next dose, skip the missed one and continue with your regular schedule.
Storage
- Store Rolnox 60 Injection 0.6ml at room temperature.
- Keep the medicine away from extreme heat and direct sunlight.
- Do not expose the product to moisture or damp conditions.
- Always keep Rolnox 60 Injection 0.6ml out of reach of children.
Special Dietary And Lifestyle Recommendation
- For those at risk of deep vein thrombosis, it would be beneficial to increase physical activity where possible. Regular movement can help improve blood flow, reducing the chance of clot formation.
- If you are managing heart-related issues with Rolnox 60 Injection 0.6ml, adopting a heart-friendly diet can be advantageous. This includes limiting your intake of saturated fats and cholesterol, while increasing consumption of fruits, vegetables, and whole grains.
Fact Box
| Dosage Forms Available | Injection |
| Habit Forming | No |
| Ailment | Deep Vein Thrombosis, Unstable Angina, Myocardial Infarction |
| Drug Category | Antithrombotic Agent |
| Therapeutic Category | Anticoagulant |
Frequently Asked Questions (FAQs)
What is Rolnox 60 Injection 0.6ml used for?
Rolnox 60 Injection 0.6ml is an anticoagulant medicine used to prevent and manage conditions like deep vein thrombosis, unstable angina, and some types of heart attacks.
How does Rolnox 60 Injection 0.6ml work?
Enoxaparin sodium, the active ingredient in Rolnox 60 Injection 0.6ml, works by enhancing the inhibition of specific blood clotting factors, preventing the formation of harmful blood clots.
How is Rolnox 60 Injection 0.6ml administered?
Rolnox 60 Injection 0.6ml is administered subcutaneously, meaning it is injected into the fatty layer just under your skin. Always follow your doctor's instructions.
Can I use Rolnox 60 Injection 0.6ml if I am allergic to pork products?
No. If you are allergic to pork products, enoxaparin or heparin, you should not use Rolnox 60 Injection 0.6ml.
What are the possible side effects of Rolnox 60 Injection 0.6ml?
Possible side effects include bleeding at any site, elevated liver enzymes, local irritation at injection sites, and osteoporosis with long-term use.
Can I take other medicines while using Rolnox 60 Injection 0.6ml?
Certain medicines like warfarin, ibuprofen or naproxen and alteplase or eptifibatide can increase the risk of bleeding when taken with Rolnox 60 Injection 0.6ml. Always inform your doctor about all the medicines you are currently taking.
Can pregnant women or nursing mothers use Rolnox 60 Injection 0.6ml?
Rolnox 60 Injection 0.6ml should be used during pregnancy only if clearly needed and it is unknown whether it is excreted in human milk. Always consult your doctor .
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Manufacturer details
Plot No.13,14,99& 100, Phase II, IDA Pashamylaram, Patancheru(M), Sangareddy District, Telangana State. Pin:502307
Country of origin: INDIA
Country of origin: INDIA
Expiry on or after: January 2027
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Address: 6th floor, Urmi Corporate Park Solaris, Saki Vihar Road, Andheri East, Mumbai 400071
References
- Enoxaparin: Uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB01225
- National Center for Biotechnology Information (2024). PubChem Compound Summary for, Enoxaparin Sodium. Retrieved June 15, 2024 from https://pubchem.ncbi.nlm.nih.gov/compound/Enoxaparin-Sodium
- Jupalli, A., & Iqbal, A. M. (2023, August 28). Enoxaparin. StatPearls - NCBI Bookshelf. https://www.ncbi.nlm.nih.gov/books/NBK539865/
- Enoxaparin injection: MedlinePlus drug information. (n.d.). MedlinePlus - Health Information from the National Library of Medicine. https://medlineplus.gov/druginfo/meds/a601210.html
- Generic Enoxaparin questions and answers. (2018, February 6). U.S. Food and Drug Administration. https://www.fda.gov/drugs/postmarket-drug-safety-information-patients-and-providers/generic-enoxaparin-questions-and-answers
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