Clexane Injection is an anticoagulant (blood thinner) used to prevent and treat harmful blood clots in the body. It contains Enoxaparin, a low-molecular-weight heparin that blocks specific proteins responsible for clot formation. It is vital for patients at risk of deep vein thrombosis (DVT), pulmonary embolism, and complications from unstable angina or certain types of heart attacks.
This injection is frequently prescribed after major surgeries, such as hip or knee replacements, or for people who are bedridden for long periods, as these situations increase the risk of clot formation. By maintaining smooth blood flow, it significantly reduces the chances of a clot traveling to the lungs, brain, or heart. It provides critical protection during recovery from high-risk medical events.
The injection is typically administered under the skin (subcutaneously) in the abdominal area. Follow your doctor’s instructions carefully or have a healthcare professional administer it. Inform your doctor if you have a history of bleeding disorders, kidney disease, or a low platelet count. It is important to report any unusual bruising or bleeding to your healthcare provider immediately.
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Clexane 60mg Injection 0.6ml
Pre-filled syringe of 0.6 ML
MRP ₹705.41
₹564.33
₹1175.68/ML
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CompositionAbout Clexane 60mg Injection 0.6ml
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Uses of Clexane 60mg Injection 0.6ml
Clexane Injection is used to prevent and treat blood clots such as deep vein thrombosis and pulmonary embolism. It is commonly given after surgery, during prolonged bed rest, dialysis, or in people at high risk of clot formation. It is also used with aspirin to reduce the risk of heart attacks and unstable angina and to prevent clot recurrence in cancer patients.
Directions for Use of Clexane 60mg Injection 0.6ml
Administer Clexane Injection as follows:
It is administered as a subcutaneous injection, usually in the abdominal area.
Do not inject into the muscle.
Alternate between left and right sides of the abdomen for each injection.
Gently pinch the skin and insert the entire length of the needle vertically into the fatty tissue.
Do not rub the injection site afterwards.
For specific advice, consult your doctor.
Route of Administration
Clexane Injection is administered subcutaneously.
Side Effects of Clexane 60mg Injection 0.6ml
Common side effects of Clexane Injection include minor bleeding such as easy bruising or nosebleeds, along with pain, redness, or irritation at the injection site.
Management Of Side Effects:
Most side effects are temporary and generally harmless, which resolve on discontinuing the use of Clexane Injection. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.
Here are some general guidelines for managing common side effects:
Bleeding: If you notice minor bleeding like bruising or nosebleeds, try to avoid activities that could cause injury.
Pain at injection site: To manage pain at the injection site, try alternating between the left and right sides of your abdomen for each dose.
How Clexane 60mg Injection 0.6ml Works?
Clexane Injection contains enoxaparin (60 mg). This active ingredient works in the body through several mechanisms:
Enhances Antithrombin III: Enoxaparin boosts the inhibitory effects of antithrombin III, a natural substance in our bodies that helps thin the blood.
Inactivates Clotting Factors: By accelerating the activity of antithrombin III, enoxaparin deactivates two crucial clotting factors - Factor Xa and thrombin (Factor IIa).
Prevents Blood Clots: By inhibiting these clotting factors, enoxaparin effectively prevents the formation and growth of blood clots.
Safety Measures & Warnings
Pregnancy
Caution is advised while taking Clexane Injection if you are pregnant. It is best to consult your doctor before taking this medicine.
Breastfeeding
The effects of Clexane Injection on nursing infants are unknown as it may be excreted in breast milk. Please consult your doctor before taking this medicine if you are breastfeeding.
Alcohol
There is no known interaction between Clexane Injection and alcohol. However, it's always a good idea to consult your doctor if you drink alcohol regularly.
Liver
If you have liver health issues, caution is advised before using Clexane Injection. It's wise to discuss these concerns with your doctor before starting this medicine.
Kidney
It's important to consult your doctor before taking Clexane Injection if you have any history of kidney problems. Your doctor will guide you based on your health status.
Use In Driving And Operating Machinery
There are no known effects of Clexane Injection on the ability to operate machinery or drive. However, if you experience any side effects that could impair these abilities, please speak with your doctor.
Allergy
Clexane Injection should not be taken if you have known hypersensitivity to enoxaparin, heparin, or pork products. If you have any allergies, please discuss them with your doctor before starting this medication.
Children
Clexane Injection is not recommended for children under 18 years of age. Always consult your doctor before giving any medicine to a child.
Older Patients
Older patients should take Clexane Injection under medical supervision as they may be more susceptible to its side effects. Caution is advised if patients are above 70 years of age. Your doctor will guide you based on your health status.
Interactions of Clexane 60mg Injection 0.6ml
Drug-Drug Interactions
Clexane Injection interacts with the following medicines:
Anticoagulants: These medicines, like warfarin or dabigatran, when taken with Clexane Injection, can potentially increase the risk of bleeding.
Antiplatelet drugs: Medicines such as clopidogrel and aspirin can enhance the blood-thinning effects of Clexane Injection, increasing the risk of bleeding.
Non-Steroidal Anti-Inflammatory Drugs (NSAIDs): When taken with Clexane Injection, NSAIDs like ibuprofen and naproxen can increase the risk of bleeding.
Drug-Food Interactions
There are no known specific food interactions with Clexane Injection.
Drug-Disease Interactions
Clexane Injection interacts with the following diseases:
Bleeding disorders: In patients with conditions like haemophilia or thrombocytopenia, Clexane Injection could exacerbate bleeding risks.
Uncontrolled hypertension: Clexane Injection might increase the risk of bleeding in people with severe uncontrolled high blood pressure.
Gastrointestinal ulceration: Patients with a history of stomach ulcers should exercise caution as Clexane Injection could increase bleeding risks.
Dosage of Clexane 60mg Injection 0.6ml
Daily Dose
Your doctor will determine the appropriate dosage of Clexane Injection based on your individual condition and response to treatment. Always adhere to this prescribed dosage and consult your doctor before making any changes.
Over Dose
Overdosing on Clexane Injection could lead to an increased risk of bleeding, such as prolonged bleeding from cuts or nosebleeds. If you suspect an overdose, inform your doctor promptly.
Missed Dose
If you miss a dose of Clexane Injection, administer it as soon as you remember. If it's nearly time for the next dose, skip the missed one and return to your regular schedule. Never alter your dosage without consulting your doctor.
Storage
Store the Clexane Injection at room temperature, ideally below 25°C.
Keep it away from direct heat and light; do not refrigerate or freeze it.
Always keep the medication out of reach of children.
Special Dietary And Lifestyle Recommendation
Since Clexane Injection is used to manage blood clots, try to include foods rich in Omega-3 fatty acids such as fish, walnuts, and flaxseeds in your diet as they are known to promote heart health.
Engage in regular light physical activities such as walking or stretching exercises to improve circulation and prevent blood clot formation. Always consult your doctor before starting any new exercise regimen.
Fact Box
| Dosage Forms Available | Injection |
| Habit Forming | No |
| Ailment | Deep Vein Thrombosis, Pulmonary Embolism |
| Drug Category | Anticoagulant Enhancer |
| Therapeutic Category | Anticoagulant |
Frequently Asked Questions (FAQs)
What is Clexane Injection?
It's an anticoagulant medication containing enoxaparin that helps prevent and manage harmful blood clots.
How does Clexane Injection work?
It enhances the effect of a natural blood-thinner in your body, reducing the formation of blood clots.
What is Clexane Injection used for?
Mainly used to prevent deep vein thrombosis (DVT) and pulmonary embolism, especially in surgery patients or those immobilised for long periods.
How is Clexane Injection administered?
It's administered as a subcutaneous injection, usually in the abdomen, not into the muscle.
What are the side effects of Clexane Injection?
The most common side effect is bleeding; others include irritation at the injection site and rarely, allergic reactions.
Who should be cautious using Clexane Injection?
People with bleeding disorders, uncontrolled high blood pressure, stomach ulcers, diabetic eye disease, or recent brain/eye surgeries should use caution.
Can I take other medications with Clexane Injection?
Some medicines may increase bleeding risk when taken with Clexane Injection; always inform your doctor about all your medications.
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Manufacturer details
Country of origin: FRANCE
References
MedlinePlus. (n.d.). Enoxaparin: MedlinePlus Drug Information. Retrieved 1 April 2024, from https://medlineplus.gov/druginfo/meds/a601210.html
Enoxaparin: Uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB01225
Jupalli, A., & Iqbal, A. M. (2023, August 28). Enoxaparin. StatPearls - NCBI Bookshelf. https://www.ncbi.nlm.nih.gov/books/NBK539865/
DailyMed - ENOXAPARIN SODIUM injection ENOXAPARIN SODIUM injection. (n.d.). https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=3e6bf2b3-9339-4104-bda3-ad86a1949703
Disclaimer
We, at Truemeds make a diligent attempt to deliver accurate, expert- drafted and thoroughly reviewed medicine related information to our consumers. However, it should, by no means, be considered a substitute for prescription from a certified doctor or a trustworthy doctor-patient relationship. In fact we detest any form of self medication without expert advice. The sole purpose of the information on our portal is to educate our consumers, which helps improve the communication between a doctor and a patient. The information by no means is complete in its entirety and should not be used to diagnose or treat any medical condition. No amount of information can replace the experience and expertise of a doctor, therefore his/her advice always holds priority and should be followed appropriately.
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