Priglip M20/1000 Tablet 10: Uses, Side Effects, Price & Substitutes

About Priglip M20/1000 Tablet 10

Priglip M20/1000 Tablet 10 is used to help control blood sugar in adults with type 2 diabetes when diet and exercise alone, or metformin alone, are not enough. It combines teneligliptin, a DPP-4 inhibitor, with extended-release metformin.

Teneligliptin raises levels of incretin hormones, prompting the pancreas to release more insulin when blood sugar rises, while metformin reduces glucose production by the liver and improves the body's sensitivity to insulin. Good blood sugar control helps reduce the long-term risk of complications such as kidney, eye and nerve damage.

This tablet is usually taken as prescribed with the evening meal and should be swallowed whole, not crushed or chewed, since it is an extended-release formulation. Take it at the same time each day and keep up regular blood sugar monitoring.

Tell your doctor about any kidney or liver problems, heart failure, or planned surgery or imaging with contrast dye, as metformin may need to be stopped temporarily. Avoid excess alcohol, and seek medical advice if you notice unusual muscle pain, breathlessness or fatigue, which can rarely indicate lactic acidosis.

Frequently Asked Questions (FAQs)

What is Priglip M20/1000 Tablet 10 used for?

Priglip M20/1000 Tablet 10 is used to manage blood sugar levels in adults with type 2 diabetes, particularly those not managed by metformin alone.

How does Priglip M20/1000 Tablet 10 work?

The tablet contains two active ingredients: teneligliptin and metformin. Teneligliptin increases insulin secretion, and metformin works mainly by reducing glucose production in the liver.

How should I take Priglip M20/1000 Tablet 10?

You should swallow the Priglip M20/1000 Tablet 10 whole as directed by your doctor. Do not split, crush or chew the tablet.

What are some of the common side effects of this medicine?

Common side effects of Priglip M20/1000 Tablet 10 include diarrhoea, nausea, vomiting, and hypoglycaemia (low blood sugar).

What precautions should I take while using Priglip M20/1000 Tablet 10?

Avoid excessive alcohol intake and monitor renal function regularly. Inform your doctor if you notice any signs of lactic acidosis or hypersensitivity.

Can I use Priglip M20/1000 Tablet 10 during pregnancy?

No, this medicine is not recommended during pregnancy. Consult your doctor for alternatives.

How should I store my Priglip M20/1000 Tablet 10?

Store them at room temperature (15-30°C) in a dry place, away from light and moisture. Keep them out of the reach of children.

References

Swami, O., Sharma, S. K., Panneerselvam, A., Singh, K. P., Parmar, G., & Gadge, P. (2016). Teneligliptin in management of type 2 diabetes mellitus. Diabetes, Metabolic Syndrome and Obesity, Volume 9, 251–260. https://doi.org/10.2147/dmso.s106.
Reference ID: 4079189, FDA reference, GLUCOPHAGE. https://www.accessdata.fda.gov/drugsatfda_docs/label/2017/020357s037s039,021202s021s023lbl.pdf
Zhu, M., Guan, R., & Ma, G. (2023). Efficacy and safety of teneligliptin in patients with type 2 diabetes mellitus: a Bayesian network meta-analysis. Frontiers in endocrinology, 14, 1282584. https://doi.org/10.3389/fendo.2023.1282584
Ji, L., Li, L., Ma, J., Li, X., Li, D., Meng, B., Lu, W., Sun, J., Liu, Y., Takayanagi, G., & Wang, Y. (2021). Efficacy and safety of teneligliptin added to metformin in Chinese patients with type 2 diabetes mellitus inadequately controlled with metformin: A phase 3, randomized, double-blind, placebo-controlled study. Endocrinology, diabetes & metabolism, 4(2), e00222. https://doi.org/10.1002/edm2.222
Kim, M. K., Rhee, E. J., Han, K. A., Woo, A. C., Lee, M. K., Ku, B. J., Chung, C. H., Kim, K. A., Lee, H. W., Park, I. B., Park, J. Y., Chul Jang, H. C., Park, K. S., Jang, W. I., & Cha, B. Y. (2015). Efficacy and safety of teneligliptin, a dipeptidyl peptidase-4 inhibitor, combined with metformin in Korean patients with type 2 diabetes mellitus: a 16-week, randomized, double-blind, placebo-controlled phase III trial. Diabetes, obesity & metabolism, 17(3), 309–312. https://doi.org/10.1111/dom.12424

Disclaimer

We, at Truemeds make a diligent attempt to deliver accurate, expert- drafted and thoroughly reviewed medicine related information to our consumers. However, it should, by no means, be considered a substitute for prescription from a certified doctor or a trustworthy doctor-patient relationship. In fact we detest any form of self medication without expert advice. The sole purpose of the information on our portal is to educate our consumers, which helps improve the communication between a doctor and a patient. The information by no means is complete in its entirety and should not be used to diagnose or treat any medical condition. No amount of information can replace the experience and expertise of a doctor, therefore his/her advice always holds priority and should be followed appropriately.