Oxemia 50 Tablet is used to treat anemia in patients suffering from chronic kidney disease (CKD). It helps improve hemoglobin levels, which significantly reduces symptoms of exhaustion, physical weakness, and shortness of breath. This medication is essential for enhancing the quality of life and physical endurance in patients whose kidneys cannot produce enough of the natural hormones needed for blood cell production.
This medicine contains Desidustat, an oral hypoxia-inducible factor-prolyl hydroxylase (HIF-PH) inhibitor. It works by stimulating the body's natural response to low oxygen levels, thereby increasing the production of erythropoietin and improving iron utilization. This process encourages the bone marrow to produce more red blood cells, ensuring better oxygen delivery to all vital organs.
This medication should be taken exactly as prescribed by your doctor, and your hemoglobin levels will need regular monitoring to adjust the dosage. It is often used as a more convenient oral alternative to injectable erythropoietin stimulating agents. Consult your healthcare provider regarding any history of uncontrolled high blood pressure or liver issues before beginning this therapy.
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Oxemia 50 Tablet 6
Zydus Lifesciences Limited
Strip of 6 Units
MRP ₹679.6
₹570.86
₹113.27/Units
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CompositionAbout Oxemia 50 Tablet 6
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Uses of Oxemia 50 Tablet 6
Oxemia 50 Tablet is used to treat anaemia associated with chronic kidney disease. It increases red blood cell production, improves haemoglobin levels, enhances oxygen delivery, and helps reduce fatigue and weakness.
Directions for Use of Oxemia 50 Tablet 6
Here's how you should take Oxemia 50 Tablet:
- Swallow the tablet whole with a glass of water. Do not crush or chew it.
- Take this medicine at the same time each day to help you remember it.
- Continue taking this medicine for as long as your doctor recommends.
- It's crucial not to stop taking this medicine without consulting your doctor first.
Route of Administration
Oxemia 50 Tablet is taken orally.
Side Effects of Oxemia 50 Tablet 6
Oxemia 50 Tablet may cause side effects such as fatigue, headache, nausea, cough, dizziness, and mild stomach upset. Seek medical advice if these effects persist.
Management Of Side Effects:
Most side effects are temporary and generally harmless, which resolve on discontinuing the use of Oxemia 50 Tablet. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.
Here are some guidelines for managing common side effects:
Fatigue: Consider taking this medicine at night if it causes you fatigue during the day.
Nausea: Try taking Oxemia 50 Tablet with food or milk to lessen this effect.
How Oxemia 50 Tablet 6 Works?
Oxemia 50 Tablet contains Desidustat (50 mg). It works in the following ways:
Hypoxia-Inducible Factor Prolyl Hydroxylases Inhibition: inhibits an enzyme group called Hypoxia-Inducible Factor Prolyl Hydroxylases (HIF-PH). These enzymes usually suppress the action of Hypoxia Inducible Factors (HIFs), which are proteins that respond to low oxygen levels in the body.
Stimulation of Erythropoiesis: By inhibiting HIF-PH, desidustat allows HIFs to increase production of erythropoietin, a hormone that stimulates the formation of red blood cells in bone marrow. This helps manage anaemia and increase oxygen-carrying capacity in the bloodstream.
Iron Metabolism Regulation: Desidustat also promotes better iron absorption and utilisation, further aiding in red blood cell production.
Safety Measures & Warnings
Pregnancy
While taking Oxemia 50 Tablet during pregnancy, caution is advised. It is best to consult your doctor before starting this medication.
Breastfeeding
Breastfeeding mothers should exercise caution when taking Oxemia 50 Tablet. Discuss with your doctor to understand the potential risks and benefits.
Alcohol
Caution is advised while consuming alcohol during the course of Oxemia 50 Tablet. Your doctor can provide guidance based on your health status.
Liver
If you have mild to moderate liver impairment, caution is recommended before starting Oxemia 50 Tablet. This medicine may not be suitable for those with severe liver diseases.
Kidney
For those with kidney problems, it's advisable to consult your doctor before taking Oxemia 50 Tablet. They will evaluate if this medication is appropriate for you.
Use In Driving And Operating Machinery
While on Oxemia 50 Tablet, careful attention should be paid while operating heavy machinery or driving due to the potential for dizziness or impaired concentration.
Allergy
If you are allergic to desidustat or any other ingredients in Oxemia 50 Tablet, avoid using this medicine. Always check the ingredients before starting a new medication.
Children
The use of Oxemia 50 Tablet in children under 18 years of age is not recommended without a doctor's supervision.
Older Patients
Older patients might be more susceptible to side effects of Oxemia 50 Tablet and may have liver and kidney issues. Therefore, they should take this medicine under medical supervision, especially if they are above 70 years of age.
Interactions of Oxemia 50 Tablet 6
Drug-Drug Interactions
Oxemia 50 Tablet interacts with the following medicines:
Anti-hypertensive medicines: Oxemia 50 Tablet may potentially increase the effect of specific medications like lisinopril and amlodipine, raising the risk of low blood pressure.
Anti-diabetic medicines: The use of Oxemia 50 Tablet may affect blood glucose control, thereby reducing the effectiveness of certain anti-diabetic medicines such as metformin.
Blood thinners: Concomitant use of blood thinners such as warfarin and aspirin with Oxemia 50 Tablet might increase the risk of bleeding.
Drug-Food Interactions
Certain food items can interact with Oxemia 50 Tablet.
Grapefruit: Consuming grapefruit while taking this medicine could affect its absorption in your body.
Drug-Disease Interactions
Oxemia 50 Tablet interacts with the following diseases:
Liver disease: Individuals suffering from liver disease should be cautious, as this medication might exacerbate their condition.
Kidney disease: People with kidney disease may experience complications as this medicine could potentially worsen their condition.
Cardiovascular disease: Patients with cardiovascular conditions need to be careful since Oxemia 50 Tablet could increase the risk of adverse cardiac events.
Dosage of Oxemia 50 Tablet 6
Daily Dose
The daily dose of Oxemia 50 Tablet should be taken as directed by your doctor. The dosage may vary depending on factors like the severity of your condition and how you respond to the medicine. Always stick to the prescribed dosage and never exceed it without consulting your doctor.
Over Dose
In case of an overdose, you might experience side effects such as nausea and dizziness. If you suspect that you've taken more than the prescribed amount of Oxemia 50 Tablet, inform your doctor right away.
Missed Dose
If you forget to take a dose of Oxemia 50 Tablet, try to take it as soon as you remember. But if it's nearly time for your next dose, miss out on the forgotten one and continue with your regular schedule. Never increase your dosage without discussing it with your doctor.
Storage
Always store Oxemia 50 Tablet in a cool and dry place, ideally at a temperature below 30 degrees Celsius.
Keep it away from direct sunlight and moisture.
Do not store it in the bathroom or near a window.
Ensure it is out of reach of children.
Special Dietary And Lifestyle Recommendation
Maintain a balanced diet high in iron-rich foods like spinach, lentils, and meat, as this can support your body when managing conditions treated by Oxemia 50 Tablet.
Regular mild to moderate exercise can also assist by improving circulation, which is beneficial for conditions managed by Oxemia 50 Tablet. Remember to consult your doctor before starting any new exercise routine.
Fact Box
| Dosage Forms Available | Tablet |
| Habit Forming | No |
| Ailment | Chronic Kidney Disease, Anaemia |
| Drug Category | HIF-PH Inhibitor |
| Therapeutic Category | Anti-Anaemic |
Frequently Asked Questions (FAQs)
What is the Oxemia 50 Tablet used for?
Oxemia 50 Tablet is used to manage anaemia related to chronic kidney disease.
How should I take Oxemia 50 Tablet?
You should take the Oxemia 50 Tablet orally, as directed by your doctor.
What if I miss a dose of Oxemia 50 Tablet?
If you miss a dose, take it as soon as you remember. If it's close to your next dose, skip the missed one and continue your regular schedule.
Can I take Oxemia 50 Tablet during pregnancy?
Consult your doctor before taking Oxemia 50 Tablet during pregnancy. It's crucial to discuss the benefits and risks with them.
Can I consume alcohol while taking Oxemia 50 Tablet?
There are no known interactions between alcohol and the Oxemia 50 Tablet but it's always best to consult your doctor for advice.
What should I do if I overdose on Oxemia 50 Tablet?
In case of an overdose, seek immediate medical attention or contact your nearest healthcare centre right away.
Are there any known side effects of Oxemia 50 Tablet?
Yes, there might be potential side effects. Common ones include fatigue and diarrhoea. However, if any side effect persists or worsens, please contact your doctor promptly.
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Manufacturer details
Country of origin: INDIA
References
Desidustat: Uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB16135
Dhillon, S. (2022). Desidustat: first approval. Drugs, 82(11), 1207–1212. https://doi.org/10.1007/s40265-022-01744-w
Agrawal, D., Varade, D., Shah, H., Nazar, A., Krishnan, J., Shukla, V., Ramakrishna, C., Galahitiyawa, M. C. B., Mavani, S. B., Rajanna, S., Jikki, P., De Silva, S., Ruhela, V., Koradia, P., Kansagra, K., Kanani, P., Sharma, N., Zala, K., & Parmar, D. (2022). Desidustat in Anemia due to Non-Dialysis-Dependent Chronic Kidney Disease: A Phase 3 Study (DREAM-ND). American Journal of Nephrology, 53(5), 352–360. https://doi.org/10.1159/000523961
Patel, V. J., Joharapurkar, A., Kshirsagar, S. G., Patel, M. S., Savsani, H. H., Dodiya, H. S., Rakhasiya, M. H., Kajavadara, C., Valani, D., & Jain, M. R. (2024). HIF-PHD inhibitor desidustat ameliorates iron deficiency anemia. Toxicology and Applied Pharmacology, 483, 116832. https://doi.org/10.1016/j.taap.2024.116832
Joharapurkar, A. A., Patel, V. J., Kshirsagar, S. G., Patel, M. S., Savsani, H. H., & Jain, M. R. (2021). Prolyl hydroxylase inhibitor desidustat protects against acute and chronic kidney injury by reducing inflammatory cytokines and oxidative stress. Drug Development Research, 82(6), 852–860. https://doi.org/10.1002/ddr.21792
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We, at Truemeds make a diligent attempt to deliver accurate, expert- drafted and thoroughly reviewed medicine related information to our consumers. However, it should, by no means, be considered a substitute for prescription from a certified doctor or a trustworthy doctor-patient relationship. In fact we detest any form of self medication without expert advice. The sole purpose of the information on our portal is to educate our consumers, which helps improve the communication between a doctor and a patient. The information by no means is complete in its entirety and should not be used to diagnose or treat any medical condition. No amount of information can replace the experience and expertise of a doctor, therefore his/her advice always holds priority and should be followed appropriately.
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