Oxemia 100 Tablet 6

Zydus Lifesciences Limited

Strip of 6 Units

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Old MRP ₹1450

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₹226.56/Units

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Composition

Desidustat (100 Mg)

Strength:

25 MG 50 MG 100 MG

Oxemia 100 Tablet is used to treat anaemia in adults with chronic kidney disease (CKD). It helps the body produce more red blood cells, improving oxygen levels and reducing fatigue.

It contains Desidustat 100 mg, a medicine that belongs to the class of HIF-PH inhibitors. It is effective for CKD patients, whether or not they are on dialysis. Take Oxemia 100 Tablet exactly as prescribed by your doctor for safe and effective treatment.

Before starting this medicine, it's important you consult your doctor who will advise on the correct dosage and frequency based on your health condition. If you have any pre-existing conditions or are taking other medicines, inform your doctor. Also, if you experience any side effects while on this medicine, notify your doctor right away. Continue taking this medicine for the duration prescribed by your doctor for optimal results.

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Oxemia 100 Tablet is used for the treatment of anemia caused by chronic kidney disease. It contains Desidustat, which boosts the body’s production of red blood cells and hemoglobin, helping reduce symptoms like fatigue and shortness of breath.

Here's how to take Oxemia 100 Tablet:

Thoroughly follow the dosage and duration guidelines provided by your doctor for taking this medicine.
Do not change or exceed the prescribed dose without consulting your doctor.
Avoid discontinuing this medication without your doctor's advice. Always consult your doctor before stopping.
Adhere to the diet plan recommended by your doctor.

Oxemia 100 Tablet is taken orally.

Most common side effects of Oxemia 100 Tablet include abdominal pain, vomiting, headache, fever, weakness, and swelling in the ankles or feet. Some people may also experience dizziness, fatigue, nausea, or changes in blood counts. Severe symptoms like shortness of breath, chest pain, or unusual bleeding require immediate medical attention.

Managing the Side Effects:

Most side effects are temporary and generally harmless, which resolve upon discontinuing the use of Oxemia 100 Tablet. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

Oxemia 100 Tablet contains desidustat (100 mg), which works on the body as follows:

Stabilises HIF-α: Desidustat works by blocking enzymes that usually degrade HIF-α subunits under normal oxygen conditions. By stabilising HIF-α, it mimics a state of cellular hypoxia.
Triggers HIF-mediated gene transcription: The stabilisation of HIF-α triggers the transcription of genes involved in erythropoiesis, iron metabolism, and oxygen delivery to tissues.
Increases endogenous EPO production: By triggering HIF-mediated gene transcription, desidustat effectively increases the production of EPO within the body.
Enhances iron absorption and mobilisation: The increase in EPO production enhances iron absorption and mobilisation, ultimately correcting anaemia.

Pregnancy

Is it safe to use Oxemia 100 Tablet during pregnancy?

Caution is advised while taking Oxemia 100 Tablet if you are pregnant. It is best to consult your doctor before taking this medicine.

Breastfeeding

Is it safe to consume Oxemia 100 Tablet during breastfeeding?

If you're breastfeeding, discuss this with your doctor before starting Oxemia 100 Tablet. Your doctor can explain the risks and benefits.

Alcohol

Is it safe to drink alcohol while taking Oxemia 100 Tablet?

It's always wise to discuss any alcohol consumption with your doctor while on this medication as it may impact overall health.

Liver

Is it advisable to take Oxemia 100 Tablet when experiencing liver problems?

If you have liver problems, discuss them with your doctor before starting Oxemia 100 Tablet. This medicine may affect liver function, so caution is advised.

Kidney

Is it advisable to consume Oxemia 100 Tablet when experiencing kidney problems?

Since Oxemia 100 Tablet is used to manage anaemia in patients with chronic kidney disease, your kidney health will be a key consideration in its use. Discuss any kidney-related concerns with your doctor.

Using Machines & Driving

Is it safe to operate heavy machinery or drive when using Oxemia 100 Tablet?

Oxemia 100 Tablet may cause dizziness or fatigue. If you experience these side effects, avoid driving or operating heavy machinery until you feel well again.

Allergy

Are there any specific conditions that should be considered before taking Oxemia 100 Tablet?

Oxemia 100 Tablet should not be used if you're allergic to desidustat or any other ingredients in the tablet. Always inform your doctor about any known allergies before starting this medicine.

Children

Is Oxemia 100 Tablet suitable for infants or children?

Oxemia 100 Tablet is indicated for adult patients and is not recommended for use in children. Always consult a doctor before giving any medicine to a child.

Older Patients

Is Oxemia 100 Tablet suitable for older patients?

Older patients should take Oxemia 100 Tablet under medical supervision as they may be more susceptible to its side effects. Caution is advised if patients are above 70 years of age. Your doctor will guide you based on your health status.

Drug-Drug Interactions

Oxemia 100 Tablet interacts with the following medicines:

Phosphate Binders: Medicines like sevelamer and lanthanum carbonate may reduce desidustat's absorption. You should take Oxemia 100 Tablet at least 2 hours before or 4 hours after taking these medicines.
CYP2C8 Inhibitors: Medicines such as gemfibrozil can increase desidustat levels in your body, raising the risk of side effects. If possible, avoid taking these together.
Anticoagulants and Antiplatelets: Medicines such as warfarin, aspirin, and clopidogrel can heighten your risk of bleeding when taken with Oxemia 100 Tablet. Your doctor will closely monitor and adjust doses as needed.

Drug-Food Interactions

There are no specific food interactions with Oxemia 100 Tablet.

Drug-Disease Interactions

Oxemia 100 Tablet interacts with the following diseases:

Seizure Disorders: If you have a history of seizures, Oxemia 100 Tablet could potentially trigger an episode. Consult your doctor about this potential interaction.
Blood Disorders: If you've ever had a blood disorder like sickle cell anaemia, Oxemia 100 Tablet could worsen your condition. It's important to discuss any such history with your doctor before starting this medicine.

Daily Dose

The daily dose of Oxemia 100 Tablet should be taken as directed by your doctor. The dosage may vary, depending on your health condition and how you respond to the medicine. Always adhere to the prescribed dosage and don't exceed it without your doctor's advice.

Over Dose

If you accidentally take more Oxemia 100 Tablet than prescribed, you may experience symptoms like nausea, dizziness, or a headache. Consult your doctor for further guidance.

Missed Dose

If you forget to take a dose of Oxemia 100 Tablet, take it as soon as you remember. If it's nearly time for your next dose, simply skip the missed one and carry on with your regular schedule. Never double up on doses without consulting your doctor.

Store Oxemia 100 Tablet in a cool, dry place, ideally at a temperature below 25°C.
Shield it from direct sunlight and moisture.
Keep the medicine securely in its original packaging until you need to take it.
Ensure it's out of reach of children.
Always check the expiry date before taking the medicine.

Maintain a balanced diet rich in iron to support red blood cell production. Foods such as spinach, lentils, and lean meat can be beneficial.
Stay hydrated. Drinking plenty of water can help manage symptoms like fatigue associated with anaemia, which is often seen in chronic kidney disease patients.

Fact Box

Available Dosage Types	Tablet
Habit Forming	No
Ailment	Chronic Kidney Disease-associated Anaemia
Drug Category	HIF Prolyl Hydroxylase Inhibitor
Therapeutic Category	Anaemia of chronic kidney disease

What is Oxemia 100 tablet used for?

Oxemia 100 Tablet is used to treat anemia caused by chronic kidney disease. It stimulates erythropoietin, increasing red blood cell production.

How does Oxemia 100 Tablet work in the body?

It contains desidustat, which boosts the body's natural production of red blood cells by stabilising hypoxia-inducible factor (HIF), a protein that regulates oxygen levels in cells.

Are there any common side effects associated with Oxemia 100 Tablet?

Yes, some people may experience abdominal pain, vomiting, headache, fever, weakness, and swelling in the extremities. However, these are usually mild and temporary.

Should I take food before consuming Oxemia 100 Tablet?

You must take the medicine exactly as prescribed by your doctor.

Is Oxemia 100 Tablet safe for pregnant or breastfeeding women?

It's essential to consult your doctor before using this medicine if you are pregnant or breastfeeding.

What should I do if I miss a dose of Oxemia 100 Tablet?

If you miss a dose, take it as soon as you remember it. But if it's nearly time for your next dose, skip the missed one and stick to your regular schedule.

Can I drive or operate heavy machinery while taking Oxemia 100 Tablet?

This medicine might cause dizziness or fatigue, so avoid driving or operating heavy machinery until you know how the medicine affects you.

What is the composition of Oxemia 100 Tablet?

Oxemia 100 Tablet contains Desidustat 100 mg, a HIF-PH inhibitor that helps stimulate red blood cell production in patients with chronic kidney disease (CKD)-related anemia.

What should I avoid while taking Oxemia 100 Tablet?

While taking this medicine, avoid alcohol, smoking, and strenuous activity, as these may interfere with treatment. Do not take iron supplements or other erythropoiesis-stimulating agents unless prescribed by your doctor. It's important to attend regular check-ups to monitor blood pressure, hemoglobin levels, and iron status during treatment.

Last Updated On 14 Oct. 2025 | 10:22AM (IST)

Certified Content

Written by

Dr. Sachin Singh

Medical Team Lead & Reviewer | 6 years

MBBS

Reviewed by

Dr. Chhavi Rosha

Medical Content Writer | 9 years

BAMS, FMC, MD Resident

Check out Editorial Policy

Manufacturer details

ZYDUS CORPORATE PARK,SCHEME NO. 63, SURVEY NO. 536 KHORAJ(GANDHINAGAR),NR. VAISHNODEVI CIRC LE, , AHMEDABAD, GUJARAT, INDIA - 382481.

Country of origin: INDIA

Expiry on or after: March 2026

In case of any issues, contact us:

support@truemeds.in|09240250346

Address: 6th floor, Urmi Corporate Park Solaris, Saki Vihar Road, Andheri East, Mumbai 400071

References

CAYMAN CHEMICAL. (2022). Desidustat. https://cdn.caymanchem.com/cdn/insert/28074.pdf
Desidustat: Uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB16135
Dhillon, S. (2022). Desidustat: first approval. Drugs, 82(11), 1207–1212. https://doi.org/10.1007/s40265-022-01744-w
Desidustat in the treatment of anemia in CKD on dialysis patients - Full text view - ClinicalTrials.gov. (n.d.). https://classic.clinicaltrials.gov/ct2/show/NCT04215120
Ku, E., 1,2,3, Del Vecchio, L., 4, Eckardt, K.-U., 5, Haase, V. H., 6,7,8, Johansen, K. L., 9,10, Nangaku, M., 11, Tangri, N., 12,13, Waikar, S. S., 14, Wie˛Cek, A., 15, Michael Cheung, Jadoul, M., 17, Winkelmayer, W. C., 18, Wheeler, D. C., 19, & Conference Participants. (2023). Novel anemia therapies in chronic kidney disease: conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference. In Kidney International. https://kdigo.org/wp-content/uploads/2020/01/Novel-Anemia_In-Press.pdf

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