Meladerm Tablet 30

Inga Laboratories Pvt. Ltd.

Strip of 30 Units

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Old MRP ₹82.2

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Composition

Methoxsalen (10 Mg)

Meladerm Tablet 30 is used in photochemotherapy (PUVA therapy) for the management of vitiligo and severe psoriasis that has not responded to other treatments, and for certain other pigmentation disorders, in adults. It is used under specialist supervision alongside controlled UVA light exposure.

It contains methoxsalen, a photosensitising agent. Take it as prescribed, usually with food or milk, at the specified time before UVA exposure.

UV-protective eyewear must be worn during and for a period after each session. Strict sun avoidance and protective clothing are essential on treatment days and the day after.

Tell your doctor about any eye disease, liver problems or history of skin cancer before starting. Never expose treated skin to uncontrolled sunlight on treatment days. Report severe blistering, persistent redness or eye irritation.

Meladerm Tablet 30 is used as part of PUVA phototherapy for vitiligo and severe psoriasis in adults, under specialist supervision.

Uses of Meladerm Tablet 30 are:

Vitiligo: Used in PUVA therapy to help restore skin pigmentation.
Severe Psoriasis: Used in PUVA therapy for severe psoriasis that has not responded to other treatments.

Follow these instructions while taking Meladerm Tablet 30:

Swallow the tablet whole with a glass of water.
Take this medicine 1.5 to 2 hours before scheduled UV light exposure.
Do not crush, chew, or break the tablet.
Consult your doctor if you miss a scheduled dose.

Meladerm Tablet 30 is taken orally.

Meladerm Tablet 30 may cause some side effects that are usually mild and go away as your body adjusts to the medicine.

A few common side effects of Meladerm Tablet 30:

Skin: Skin redness and itching. A cool compress on the area can help soothe itching.
Digestive: Feeling sick (nausea). Taking small sips of water and eating plain, simple food can help ease nausea.
Neurological: Dizziness and sleep disturbances. Rising slowly from sitting or lying down can help reduce dizziness.
Skin Sensitivity: Increased sensitivity to sunlight.

If side effects do not improve or become serious, speak to your doctor right away.

Management Of Side Effects:

Most side effects are temporary and generally harmless and are resolved by discontinuing the use of Meladerm Tablet 30. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

Here are some general guidelines for managing common side effects:

Nausea: Taking Meladerm Tablet 30 with food may help reduce feelings of sickness that can occur after ingestion.
Sleep disturbances: Consider taking this medicine earlier in the day rather than in the evening to minimise its effects on your sleep pattern.

Meladerm Tablet 30 contains methoxsalen (10 mg), which works on the body as follows:

Photosensitisation: Methoxsalen makes your skin more sensitive to ultraviolet A (UVA) light, which is necessary for the medicine to be effective.
DNA interaction: When activated by UVA light, methoxsalen binds to the DNA in your skin cells, forming cross-links between DNA strands.
Melanocyte stimulation: This process triggers the activity of melanocytes (pigment-producing cells), encouraging them to multiply and migrate to affected areas.
Repigmentation: By stimulating melanocytes, the medicine helps restore normal skin colour to areas affected by vitiligo.
Cell growth regulation: In psoriasis, this medicine helps slow down the rapid skin cell turnover and reduce inflammation, a characteristic symptom of this condition.

Pregnancy

Meladerm Tablet 30 is contraindicated during pregnancy. If you are pregnant or planning to conceive, make sure to discuss this with your doctor before starting this medicine. This medicine may cause harmful effects on the developing baby.

Breastfeeding

Meladerm Tablet 30 is contraindicated for breastfeeding women. The medicine may pass into breast milk and could affect your baby. Consult your doctor to understand the potential risks and benefits.

Alcohol

Caution is advised while taking Meladerm Tablet 30 when consuming alcohol. Alcohol might increase your skin's sensitivity to sunlight, potentially worsening side effects such as skin redness or burning.

Liver

Caution is advised while taking Meladerm Tablet 30 if you have mild to moderate liver impairment. It is not recommended for severe liver diseases. Your doctor might need to adjust your dosage based on your liver function tests.

Kidney

Caution is advised before using Meladerm Tablet 30 if you have a history of any kidney problems. Your doctor might need to monitor your kidney function during treatment with this medicine.

Use In Driving And Operating Machinery

Caution is advised while driving or operating machinery after taking Meladerm Tablet 30. This medicine may cause dizziness or vision changes in some people, especially during initial treatment.

Allergy

If you have a history of allergies, especially to psoralens or similar medicines, inform your doctor before taking Meladerm Tablet 30. Individuals with conditions that cause photosensitivity should avoid this medication.

Children

Caution is advised while giving Meladerm Tablet 30 to children under 12 years of age. This medicine is generally not recommended for children unless specifically prescribed by a specialist.

Older Patients

Older patients should take Meladerm Tablet 30 under medical supervision, as they may be more susceptible to its side effects. Your doctor may prescribe a lower starting dose and monitor you more closely during treatment.

Drug-Drug Interactions

Meladerm Tablet 30 interacts with the following medicines:

Antibiotics: Medicines like doxycycline and ciprofloxacin can dangerously enhance your skin's sensitivity to light when taken with methoxsalen, increasing the risk of severe sunburn.
Diuretics: Furosemide can increase photosensitivity when combined with Meladerm Tablet 30, potentially causing severe skin reactions.
Antidiabetic medicines: Medicines such as metformin or gliclazide may have altered effectiveness when used alongside methoxsalen therapy.
Phenothiazines: Medicines such as chlorpromazine or fluphenazine can amplify light sensitivity when taken with Meladerm Tablet 30.
Herbal supplements: St. John's Wort can significantly increase photosensitivity when combined with methoxsalen, raising the risk of skin reactions.

Drug-Food Interactions

Meladerm Tablet 30 interacts with certain foods containing natural psoralens.

Celery: Contains natural psoralens that can increase your skin's sensitivity to light.
Figs: May enhance photosensitivity when consumed during treatment.
Limes: Can amplify the photosensitising effects of methoxsalen.
Parsley: Contains compounds that may increase the risk of sunburn during treatment.

Drug-Disease Interactions

Meladerm Tablet 30 interacts with the following diseases:

Photosensitivity disorders: Conditions like lupus erythematosus or porphyria cutanea tarda can worsen dramatically with methoxsalen therapy.
Skin cancer history: Patients with previous melanoma or squamous cell carcinoma are at an increased risk of cancer recurrence with this medicine.
Eye conditions: Aphakia (absence of eye lens) increases the risk of retinal damage from this photosensitizing medicine.
Cardiac conditions: High blood pressure or heart problems may worsen as methoxsalen can affect blood pressure.

Daily Dose

The daily dose of Meladerm Tablet 30 should be taken as prescribed by your doctor. Your dosage may vary based on your body weight, skin type, condition severity, and how you respond to treatment. Never adjust your dose without consulting your doctor.

Over Dose

An overdose of Meladerm Tablet 30 may cause severe nausea, dizziness, and extreme skin sensitivity. You might also experience intense redness, blistering, or swelling after light exposure. Contact your doctor if you suspect an overdose has occurred.

Missed Dose

If you forget to take Meladerm Tablet 30, take it as soon as you remember, but only if your scheduled UV light therapy hasn't happened yet. Otherwise, skip the missed dose and continue with your regular schedule.

Store Meladerm Tablet 30 at room temperature.
Keep it in its original packaging in a dry place away from direct sunlight and moisture.
Avoid storing in bathrooms due to humidity fluctuations.
Always keep out of reach of children and pets.
Do not use after the expiry date printed on the package.

Avoid foods containing natural psoralens (such as celery, parsley, figs and limes) around your treatment times, as these can increase your skin's sensitivity to light.
Wear protective clothing and apply high-SPF sunscreen on non-treated areas when outdoors to protect your skin during the course of your vitiligo or psoriasis management.

Fact Box

Dosage Forms Available	Tablet
Habit Forming	No
Ailment	Vitiligo, psoriasis, cutaneous lymphoma
Drug Category	Photosensitising agent
Therapeutic Category	Anti-vitiligo

What is Meladerm Tablet 30 used for?

Meladerm Tablet 30 is used for managing vitiligo (white patches on skin), psoriasis, and sometimes certain types of skin lymphoma when combined with ultraviolet light therapy.

How does Meladerm Tablet 30 work?

It makes your skin more sensitive to ultraviolet A light. When activated by this light, methoxsalen helps stimulate pigment-producing cells in your skin to restore colour.

When should I take Meladerm Tablet 30?

You should take it 1.5 to 2 hours before your scheduled ultraviolet light therapy session, with water, as directed by your doctor.

What precautions should I follow during treatment?

Avoid sun exposure for 24 hours after taking the medicine, wear protective clothing, use sunglasses, and attend all follow-up appointments with your doctor.

Can I use Meladerm Tablet 30 if I have other skin conditions?

You should not use this medicine if you have conditions that make you sensitive to light, such as lupus or porphyria, or if you have skin cancer.

What side effects might I experience?

You may experience nausea, redness, itching, headaches, dizziness, or sleep disturbances. Severe burning or blistering requires immediate medical attention.

What foods should I avoid while using Meladerm Tablet 30?

Avoid foods containing natural psoralens such as celery, parsley, figs and limes around treatment times, as they can increase light sensitivity.

Last Updated On 30 Jul. 2026 | 11:26AM (IST)

Certified Content

Written by

Ashmita Borgohain

Medical Content Writer | 14 years

MSc (Applied Genetics)

Reviewed by

Dr. Chhavi Rosha

Medical Content Writer | 10 years

BAMS, FMC, MD Resident

Check out Editorial Policy

Manufacturer details

Inga HouseMahakali Road Andheri East Mumbai 400 093 India.

Country of origin: INDIA

Expiry on or after: February 2027

In case of any issues, contact us:

support@truemeds.in|09240250346

Address: 6th floor, Urmi Corporate Park Solaris, Saki Vihar Road, Andheri East, Mumbai 400071

References

Methoxsalen Capsules, USP 10 mg [Soft Gelatin Capsules]. (n.d.). https://dailymed.nlm.nih.gov/dailymed/medguide.cfm?setid=a6ec8292-9189-4ebd-862a-e1725eb29eef
FDA. (2021). UVADEX (Methoxsalen) Sterile Solution, 20 mcg/mL. https://www.accessdata.fda.gov/drugsatfda_docs/label/2018/020969s010lbl.pdf
Methoxsalen G.L. Pharma 20 micrograms/ml solution for blood fraction modification - Summary of Product Characteristics (SmPC) - (emc) | 15562. (n.d.). https://www.medicines.org.uk/emc/product/15562/smpc#gref
NCI Drug Dictionary. (n.d.). Cancer.gov. https://www.cancer.gov/publications/dictionaries/cancer-drug/def/methoxsalen
Methoxsalen: Uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB00553

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We, at Truemeds make a diligent attempt to deliver accurate, expert- drafted and thoroughly reviewed medicine related information to our consumers. However, it should, by no means, be considered a substitute for prescription from a certified doctor or a trustworthy doctor-patient relationship. In fact we detest any form of self medication without expert advice. The sole purpose of the information on our portal is to educate our consumers, which helps improve the communication between a doctor and a patient. The information by no means is complete in its entirety and should not be used to diagnose or treat any medical condition. No amount of information can replace the experience and expertise of a doctor, therefore his/her advice always holds priority and should be followed appropriately.

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