Mankind Pharma Limited
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CompositionGlizid-XR 30 Tablet is used to manage type 2 diabetes by controlling blood glucose levels. This sulfonylurea class medication contains gliclazide, which works by stimulating the pancreas to produce and release more insulin. Its dual action also increases the sensitivity of body tissues to insulin, helping achieve adequate glycemic control when diet, exercise, or single therapies are insufficient.
Glizid-XR 30Tablet is used for the management of type 2 diabetes mellitus to improve glycemic control by stimulating insulin release, and can be used as a monotherapy when diet and exercise are inadequate, or in combination with other oral antidiabetic agents or insulin for better blood sugar management.
Here's how you should take Glizid XR 30 Tablet:
Swallow the tablet whole with water.
Do not crush, chew, or divide the tablet.
Always take this medicine with breakfast.
It's important not to alter the dose or stop taking this medicine without consulting your doctor first.
Glizid XR 30 Tablet is taken orally.
Glizid-XR 30 Tablet may cause hypoglycaemia (low blood sugar), gastrointestinal disturbances (nausea, vomiting, stomach ache, diarrhoea), weight gain, allergic reactions (skin rashes, itching), and hepatic dysfunction. Speak with your healthcare provider if these symptoms continue.
Most side effects are temporary and generally harmless, which resolve on discontinuing the use of Glizid XR 30 Tablet. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.
Here are some guidelines for managing common side effects:
Hypoglycaemia: Carry a fast-acting carbohydrate source like a piece of fruit or a small snack with you.
Gastrointestinal disturbances: Taking your medicine with meals can help minimise these effects.
Glizid XR 30 Tablet contains gliclazide (30 mg). Here's how this active ingredient works:
Blocks ATP Sensitive Potassium Channels: Gliclazide blocks certain channels on the beta cells of your pancreas. These channels are responsible for controlling the flow of potassium ions in and out of cells.
Stimulates Insulin Secretion: By blocking these channels, gliclazide causes an increase in calcium ions within the beta cells. This triggers these cells to release more insulin into your bloodstream.
Increases Insulin Sensitivity: Not only does gliclazide stimulate insulin secretion, but it also makes your body's tissues more responsive to insulin.
Inhibits Hepatic Glucose Production: Finally, gliclazide helps reduce the amount of glucose that your liver produces. This further helps control your blood sugar levels.
Caution is advised while taking Glizid XR 30 Tablet if you are pregnant. It is best to consult your doctor before taking this medicine.
Consult your doctor before using Glizid XR 30 Tablet if you are breastfeeding, to understand the potential risks and benefits.
Drinking alcohol while taking Glizid XR 30 Tablet may increase the risk of low blood sugar (hypoglycaemia). It's advised to limit your alcohol intake or avoid it altogether.
If you have known liver issues, it's important to discuss them with your doctor before starting Glizid XR 30 Tablet as it may affect liver function.
Should you have a history of kidney problems, caution is advised before using Glizid XR 30 Tablet. Consult your doctor before starting this medicine.
Glizid XR 30 Tablet may cause dizziness or visual disturbances. If affected, avoid driving or operating machines until you know how this medicine affects you.
This medication is not recommended if you are allergic to gliclazide or other sulfonylureas. If you experience an allergic reaction, seek medical help immediately.
Glizid XR 30 Tablet should not be given to children under 18 years of age. Always consult your doctor before giving any medicine to a child.
Older patients should take Glizid XR 30 Tablet under medical supervision as they may be more susceptible to its side effects. Caution is advised if patients are above 70 years of age. Your doctor will guide you based on your health status.
Glizid XR 30 Tablet interacts with the following medicines:
Other Antidiabetic Agents: Medicines like insulin or other sulfonylureas, when taken with Glizid XR 30 Tablet, may increase the risk of low blood sugar or hypoglycaemia.
Beta-blockers and ACE Inhibitors: Medicines such as propranolol and lisinopril may hide the symptoms of low blood sugar when taken with Glizid XR 30 Tablet.
Anticoagulants: The anticoagulant effect of medicines like warfarin can be increased when used alongside Glizid XR 30 Tablet.
Glizid XR 30 Tablet doesn't have any known specific food interactions. However, it's recommended to maintain a balanced diet while managing diabetes.
Glizid XR 30 Tablet interacts with the following diseases:
Type 1 Diabetes Mellitus: This medicine is ineffective for people with type 1 diabetes as their bodies don't produce insulin.
Severe Renal or Hepatic Impairment: People with severe kidney or liver problems should avoid this medicine as it could worsen their condition.
Adrenal or Pituitary Insufficiency: People with adrenal or pituitary gland problems should use Glizid XR 30 Tablet cautiously as it could lead to low blood sugar.
The daily dose of Glizid XR 30 Tablet should be taken as directed by your doctor. The dosage may be adjusted depending on factors like the severity of your diabetes and your response to the medicine. It's crucial not to alter the prescribed dosage without consulting your doctor.
If you accidentally take too much of Glizid XR 30 Tablet, you might experience symptoms like sweating, shaking, palpitation, and intense hunger, which are signs of hypoglycaemia (low blood sugar). If you notice these symptoms, inform your doctor.
If you forget to take Glizid XR 30 Tablet at the scheduled time, take it as soon as you remember. However, if it’s nearly time for your next dose, skip the one you missed and continue with your usual schedule. Never double up a dose without consulting with your doctor.
Store Glizid XR 30 Tablet at room temperature, ideally between 15 to 30°C.
Keep the medicine away from light and moisture to maintain its efficacy.
Always remember to keep this medicine out of sight and reach of children.
Make sure you use Glizid XR 30 Tablet before its expiry date.
Regular physical activity is key in managing type 2 diabetes. Aim for at least 150 minutes of moderate-intensity exercise like brisk walking each week.
Adopt a balanced diet that's low in sugar and saturated fats. Focus on high-fibre foods, such as whole grains, fruits, and vegetables, which can help control your blood sugar levels.
| Available Dosage Types | ExtendedRelease Tablet |
| Habit Forming | No |
| Ailment | Type 2 Diabetes Mellitus |
| Drug Category | Sulfonylurea Antidiabetic |
| Therapeutic Category | Antidiabetic |
Glizid XR 30 Tablet helps manage type 2 diabetes in adults when diet, exercise, and a single antidiabetic medicine don't sufficiently control blood sugar levels.
Glizid XR 30 Tablet contains gliclazide which stimulates your pancreas to produce more insulin and increases your body's sensitivity to this hormone.
You should swallow the Glizid XR 30 Tablet whole with your breakfast. Do not chew, crush, or divide the tablet.
Common side effects include hypoglycaemia (low blood sugar), gastrointestinal disturbances such as nausea and diarrhoea, and weight gain.
If you're elderly, malnourished, have adrenal or pituitary insufficiency, or are experiencing severe infection, trauma or stress, consult your doctor before use.
Yes, but some medicines may interact with Glizid XR 30 Tablet, affecting its effectiveness or causing unwanted effects. Always consult your doctor first.
Store Glizid XR 30 Tablets at room temperature (1530°C), away from light and moisture. Keep out of reach of children.
Check out Editorial Policy
SANIS HEALTH INC. (2017). PRODUCT MONOGRAPH. In PRODUCT MONOGRAPH (pp. 2–31) [Report]. https://pdf.hres.ca/dpd_pm/00038817.PDF
DIAMICRON MR. (2021). DIAMICRON® MR - Product Information. https://www.tga.gov.au/sites/default/files/foi-067-1314-2.pdf
Gliclazide: Uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB01120
Sarkar, A., Tiwari, A., & Jaipur National University. (2011). Pharmacological and Pharmaceutical Profile of gliclazide: a review. In Journal of Applied Pharmaceutical Science (Vol. 01, Issue 09, pp. 11–19). https://japsonline.com/admin/php/uploads/253_pdf.pdf
Khunti, K., Hassanein, M., Lee, M., Mohan, V., & Amod, A. (2020). Role of gliclazide MR in the management of Type 2 Diabetes: Report of a symposium on Real-World Evidence and New Perspectives. Diabetes Therapy, 11(S2), 33–48. https://doi.org/10.1007/s13300-020-00833-x
We, at Truemeds make a diligent attempt to deliver accurate, expert- drafted and thoroughly reviewed medicine related information to our consumers. However, it should, by no means, be considered a substitute for prescription from a certified doctor or a trustworthy doctor-patient relationship. In fact we detest any form of self medication without expert advice. The sole purpose of the information on our portal is to educate our consumers, which helps improve the communication between a doctor and a patient. The information by no means is complete in its entirety and should not be used to diagnose or treat any medical condition. No amount of information can replace the experience and expertise of a doctor, therefore his/her advice always holds priority and should be followed appropriately.
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