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CompositionDefza 12 Tablet is used to manage various inflammatory conditions, including rheumatoid arthritis, bronchial asthma, and severe allergic conditions. It contains deflazacort, which exerts strong anti-inflammatory and immunosuppressive properties. This mechanism reduces swelling and pain by modifying the body's immune system response.
Defza 12 Tablet is used for the management of various inflammatory and autoimmune conditions, including controlling flare-ups in rheumatoid arthritis and bronchial asthma, managing allergic conditions, and as a treatment for Duchenne muscular dystrophy (DMD).
Here's how you should take Defza 12 Tablet:
Swallow the tablet whole with a glass of water. Avoid crushing or chewing it.
Do not miss a dose, but if you do, take it as soon as you remember. If it's nearly time for your next dose, skip the missed one and continue with your regular schedule.
Don't stop taking this medicine without consulting your doctor first.
Defza 12 Tablet is taken orally.
Defza 12 Tablet may cause weight gain, mood changes, insomnia, increased risk of infections, irregular menstrual periods, acne, and headache. Speak to your doctor if these symptoms worsen.
Most side effects are temporary and generally harmless, which resolve on discontinuing the use of Defza 12 Tablet. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.
Here are some general guidelines for managing common side effects:
Mood changes: If these become disruptive to daily life, try taking your tablet in the evening.
Gastrointestinal disturbances: Taking Defza 12 Tablet with food may help to lessen this effect.
Defza 12 Tablet contains deflazacort (12 mg), which works on your body in the following ways:
Anti-Inflammatory Action: Deflazacort reduces inflammation in the body. It achieves this by binding to glucocorticoid receptors, which in turn regulate the genes involved in the inflammatory process.
Immunosuppressive Activity: By binding to the same glucocorticoid receptors, deflazacort also suppresses the immune system. This action helps to manage autoimmune conditions where the immune system mistakenly attacks the body's tissues.
Caution is advised while taking Defza 12 Tablet if you are pregnant. It's best to consult your doctor before taking this medicine.
Please check with your doctor before using Defza 12 Tablet if you are breastfeeding.
It's advisable to consult your doctor for guidance on alcohol consumption while on this medicine.
If you have liver health concerns, it's advised to discuss them with your doctor before starting Defza 12 Tablet.
Caution is advised before using Defza 12 Tablet if you have a history of any kidney problems. Consulting your doctor is always a good idea before starting this medicine.
Defza 12 Tablet may affect your ability to drive or operate heavy machinery. Consult your doctor if you have any concerns.
Defza 12 Tablet should not be used if you're allergic to deflazacort or any other components of the tablet. Always inform your doctor about any known allergies before starting this medication.
Caution is advised while giving Defza 12 Tablet to children under 18 years of age. Always consult your doctor before giving any medicine to a child.
Older patients should take Defza 12 Tablet under medical supervision as they may be more susceptible to its side effects. If you are above 70 years of age, consult with your doctor who will guide you based on your health status.
Defza 12 Tablet interacts with the following medicines:
NSAIDs: Medicines like ibuprofen and naproxen can interfere with the anti-inflammatory effect of Defza 12 Tablet.
Anticoagulants: Medicines such as heparin and warfarin might have their effects amplified, increasing the risk of bleeding.
Antidiabetic agents: Medications like metformin or insulin may be less effective, leading to high blood sugar levels.
Antihypertensive medications: Medicines such as losartan or amlodipine may have their blood pressure-lowering effect reduced.
Antibiotics: Specific antibiotics like erythromycin or clarithromycin can enhance the action of Defza 12 Tablet, increasing the risk of side effects.
Anticonvulsants: Medicines like phenytoin or carbamazepine can reduce the effectiveness of Defza 12 Tablet.
No specific food interactions have been reported with Defza 12 Tablet.
Defza 12 Tablet interacts with the following diseases:
Diabetes: It may worsen blood sugar control in diabetic patients.
Hypertension: The medication might increase blood pressure levels.
Osteoporosis: It could increase bone loss further in osteoporosis patients.
Infections: It might worsen existing infections due to its immunosuppressive action.
The dosage of Defza 12 Tablet is determined by your doctor, based on factors such as the severity of your health condition and your response to the medicine. It's crucial to adhere to the prescribed dosage without exceeding it, unless advised otherwise by your doctor.
An overdose of Defza 12 Tablet may lead to common symptoms like mood changes, insomnia, and gastrointestinal disturbances. If you suspect an overdose, inform your doctor to manage these symptoms appropriately.
In case you miss a dose of Defza 12 Tablet, take it as soon as you remember. If it's nearly time for your next dose, skip the missed dose and continue with your regular schedule. It's not advisable to alter your dosage without consulting your doctor.
Store Defza 12 Tablet at room temperature, ideally below 30°C.
Choose a dry place, away from direct light and moisture.
Keep the medicine out of reach of children to prevent accidental ingestion.
Check the expiry date before using the product; do not use it if it expires.
If you're managing rheumatoid arthritis with Defza 12 Tablet, consider including omega-3 fatty acids in your diet. Foods like fish, walnuts, and chia seeds can help reduce inflammation.
For those managing bronchial asthma, avoid exposure to allergens such as dust and pet dander and refrain from smoking as this can worsen your condition.
| Available Dosage Types | Tablet |
| Habit Forming | No |
| Ailment | Rheumatoid arthritis, Bronchial asthma, Duchenne muscular dystrophy |
| Drug Category | Glucocorticoid |
| Therapeutic Category | Corticosteroid |
Defza 12 Tablet is primarily used to manage inflammatory conditions such as rheumatoid arthritis, bronchial asthma, allergies, and Duchenne muscular dystrophy.
This medicine contains deflazacort, which reduces inflammation and modifies the immune system's response, thus managing the symptoms of various conditions.
You must take the medicine as directed by your doctor.
If you miss a dose, take it as soon as you remember. However, if it's almost time for the next dose, skip the missed one.
No, sudden discontinuation of this medicine may lead to adrenal insufficiency. Always consult your doctor before making any changes to your medication routine.
Defza 12 Tablet should only be used during pregnancy if your doctor believes the benefits outweigh the potential risks to the foetus.
Common side effects include weight gain, mood changes, insomnia, and gastrointestinal disturbances. Serious side effects may include osteoporosis and hypertension, among others.
Check out Editorial Policy
Marathon Pharmaceuticals, LLC. (2017). Highlights of prescribing information. In EMFLAZA. https://www.accessdata.fda.gov/drugsatfda_docs/label/2017/208684s000,208685s000lbl.pdf
Deflazacort: Uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB11921
DailyMed - EMFLAZA- deflazacort tablet EMFLAZA- deflazacort suspension. (n.d.). https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=31b347d2-f156-4055-9d8f-7cf0df420296
Deflazacort: MedlinePlus drug information. (n.d.). https://medlineplus.gov/druginfo/meds/a617024.html
We, at Truemeds make a diligent attempt to deliver accurate, expert- drafted and thoroughly reviewed medicine related information to our consumers. However, it should, by no means, be considered a substitute for prescription from a certified doctor or a trustworthy doctor-patient relationship. In fact we detest any form of self medication without expert advice. The sole purpose of the information on our portal is to educate our consumers, which helps improve the communication between a doctor and a patient. The information by no means is complete in its entirety and should not be used to diagnose or treat any medical condition. No amount of information can replace the experience and expertise of a doctor, therefore his/her advice always holds priority and should be followed appropriately.
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