Curepzil M 5/5 Mg Tablet 10

Curasia Medilabs

Pack of 10 Units

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Composition

Donepezil (5 Mg) + Memantine (5 Mg)

Curepzil M 5/5 Mg Tablet 10 is a combination medicine used to manage moderate to severe Alzheimer's disease. It helps support memory, thinking, and general cognitive abilities, enabling patients to maintain daily activities for longer.

It contains anti-dementia medicines. Take it regularly as prescribed by your doctor, preferably at the same time each day. Do not adjust the dosage or discontinue treatment without consulting your medical specialist.

Creating a structured daily routine, maintaining cognitive stimulation, and ensuring a safe home environment support mental well-being alongside medicine.

Inform the treating doctor if the patient has a history of heart rhythm problems, stomach ulcers, asthma, or kidney conditions. Report severe nausea, persistent vomiting, or worsening confusion to the doctor promptly.

Curepzil M 5/5 Mg Tablet 10 is used to support cognitive function and daily living abilities in patients with Alzheimer's disease.

Uses of Curepzil M 5/5 Mg Tablet 10 are:

Alzheimer's Disease Management: Helps treat moderate to severe symptoms of Alzheimer's dementia.
Cognitive Support: Supports memory, reasoning, and mental clarity in progressive cognitive decline.
Daily Functioning Support: Assists patients in maintaining independence in daily routine activities.

Follow these instructions while taking Curepzil M 5/5 Mg Tablet 10:

Swallow the tablet whole with a full glass of water.
Do not crush, break, or chew the tablet.
Take this medicine regularly to get the most benefit from it.
Consult your doctor if you have any questions about using this medicine.

Curepzil M 5/5 Mg Tablet 10 is taken orally.

Curepzil M 5/5 Mg Tablet 10 may cause some side effects that are usually mild and go away as your body adjusts to the medicine.

A few common side effects of Curepzil M 5/5 Mg Tablet 10:

Digestive: Feeling sick (nausea), gas, loss of appetite, and loose motions (diarrhoea).
Neurological: Mild headache, dizziness, or drowsiness.
Musculoskeletal: Muscle cramps or localized body pain.
Urinary: Frequent urination or difficulty controlling bladder function.

If side effects do not improve or become serious, speak to your doctor right away.

Management Of Side Effects:

Most side effects are temporary and generally harmless and are resolved by discontinuing the use of Curepzil M 5/5 Mg Tablet 10. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

Here are a few measures to manage common side effects:

Nausea: Taking Curepzil M 5/5 Mg Tablet 10 with food can help reduce feelings of sickness.
Dizziness: Consider taking this medicine at bedtime to minimise the impact of dizziness on your daily activities.

Curepzil M 5/5 Mg Tablet 10 contains two active ingredients:

Memantine (5 mg): It functions as an NMDA receptor antagonist that regulates glutamate activity in the brain. Glutamate is a neurotransmitter involved in learning and memory, but excessive amounts can damage brain cells. Memantine blocks the harmful effects of excess glutamate, helping reduce symptoms of Alzheimer's disease.
Donepezil (5 mg): As a cholinesterase inhibitor, it prevents the breakdown of acetylcholine in the brain. Acetylcholine is a neurotransmitter (chemical messenger) important for memory and learning, and by increasing its levels, donepezil helps improve communication between nerve cells.

Pregnancy

Caution is advised while taking Curepzil M 5/5 Mg Tablet 10 if you are pregnant. It is best to consult your doctor before taking this medicine.

Breastfeeding

Caution is advised while taking Curepzil M 5/5 Mg Tablet 10 if you are breastfeeding. It is best to consult your doctor before taking this medicine.

Alcohol

Curepzil M 5/5 Mg Tablet 10 may cause dizziness or drowsiness, which could worsen when combined with alcohol. It is advisable to avoid alcoholic beverages while taking this medicine.

Liver

Caution is advised while taking Curepzil M 5/5 Mg Tablet 10 if you have liver problems. This medicine may affect liver function. If you have a history of liver disease, discuss this with your doctor before starting treatment.

Kidney

Caution is advised before using Curepzil M 5/5 Mg Tablet 10 if you have a history of any kidney problems. It is a good idea to consult your doctor before taking this medicine.

Use In Driving And Operating Machinery

This medicine may cause dizziness or drowsiness. Avoid driving, operating machinery, or performing tasks requiring alertness until you know how Curepzil M 5/5 Mg Tablet 10 affects you.

Allergy

If you have allergies to donepezil, memantine, or any ingredients in Curepzil M 5/5 Mg Tablet 10, inform your doctor immediately. Allergic reactions may include rash, itching, swelling, severe dizziness, or trouble breathing.

Children

Caution is advised while giving Curepzil M 5/5 Mg Tablet 10 to children under 18 years of age. Always consult your doctor before giving any medicine to a child.

Older Patients

Older patients should take Curepzil M 5/5 Mg Tablet 10 under medical supervision, as they may be more susceptible to side effects. Your doctor will guide you based on your health status, especially if you have liver or kidney issues or are taking other medicines.

Drug-Drug Interactions

Curepzil M 5/5 Mg Tablet 10 interacts with the following medicines:

Anticholinergic medicines: Medicines like oxybutynin and tolterodine may reduce the effectiveness of donepezil in Curepzil M 5/5 Mg Tablet 10 by opposing its cholinergic effects.
NMDA antagonists: Concurrent use with other NMDA blockers such as amantadine and ketamine may increase the risk of side effects due to a similar mechanism as memantine.
Antacids: Magnesium- or aluminium-containing antacids may interfere with the absorption of memantine, potentially reducing its effectiveness.
CYP3A4 inhibitors: Medicines like ketoconazole and erythromycin may increase the blood levels of donepezil, potentially causing more side effects.

Drug-Disease Interactions

Curepzil M 5/5 Mg Tablet 10 interacts with the following diseases:

Heart problems: Patients with irregular heartbeat or slow heart rate should use this medicine with caution, as donepezil may worsen these conditions.
Gastrointestinal conditions: Those with stomach ulcers or a history of gastrointestinal bleeding should be cautious, as this medicine may increase the risk of bleeding.
Kidney or liver disease: These conditions may lead to increased blood levels of memantine or donepezil, potentially causing more side effects.
Seizures: Curepzil M 5/5 Mg Tablet 10 should be used carefully in patients with seizures, as it may potentially lower the seizure threshold.

Daily Dose

The daily dose of Curepzil M 5/5 Mg Tablet 10 should be taken as prescribed by your doctor. Dosage may change based on your condition's severity and your response to treatment. Always follow the prescribed dosage and never exceed it without consulting your doctor.

Over Dose

Taking too much Curepzil M 5/5 Mg Tablet 10 may cause severe nausea, vomiting, increased sweating, slow heartbeat, dizziness, confusion, or difficulty controlling urination. Contact your doctor if you suspect an overdose has occurred.

Missed Dose

If you forget to take Curepzil M 5/5 Mg Tablet 10, take it as soon as you remember. If it's nearly time for your next dose, skip the missed one and continue your regular schedule. Never double your dose to make up for a missed one.

Store Curepzil M 5/5 Mg Tablet 10 at room temperature not exceeding 30°C.
Keep the tablet protected from moisture.
Store in the original packaging until ready to use.
Keep this medicine out of reach and sight of children.
Do not use Curepzil M 5/5 Mg Tablet 10 after the expiry date printed on the package.

Maintain a brain-healthy diet rich in omega-3 fatty acids (found in fish like salmon) and antioxidants (found in colourful fruits and vegetables), which may support cognitive function in Alzheimer's disease.
Engage in regular mental stimulation activities such as puzzles, reading, or memory games to help maintain cognitive abilities alongside your Alzheimer's management plan.

Fact Box

Dosage Forms Available	Tablet
Habit Forming	No
Ailment	Alzheimer's disease, cognitive decline, memory problems
Drug Category	NMDA antagonist, Cholinesterase inhibitor
Therapeutic Category	Anti-dementia medication

How does Curepzil M 5/5 Mg Tablet 10 work?

Curepzil M 5/5 Mg Tablet 10 works by increasing acetylcholine (a brain chemical important for memory) and regulating glutamate (another brain chemical). This helps improve thinking and memory in Alzheimer's disease.

What is Curepzil M 5/5 Mg Tablet 10 used for?

This medicine manages moderate to severe Alzheimer's disease. It helps improve memory, thinking skills, and the ability to perform daily activities in people with this type of dementia.

Can Curepzil M 5/5 Mg Tablet 10 be taken with food?

Yes, you can take this medicine with or without food, as prescribed by your doctor. Most doctors recommend taking it at bedtime for better tolerance and convenience.

What are the common side effects of Curepzil M 5/5 Mg Tablet 10?

Common side effects include nausea, headache, dizziness, diarrhoea, and loss of appetite. Most side effects are mild and often improve as your body adjusts to the medicine.

What should I tell my doctor before taking Curepzil M 5/5 Mg Tablet 10?

Inform your doctor about any heart problems, stomach ulcers, seizures, asthma, bladder issues, or kidney/liver disease you have. Also, mention all other medicines you're currently taking.

Will Curepzil M 5/5 Mg Tablet 10 affect my driving ability?

This medicine may cause drowsiness or dizziness. Avoid driving or operating machinery until you know how Curepzil M 5/5 Mg Tablet 10 affects you personally.

What should I do if I miss a dose of Curepzil M 5/5 Mg Tablet 10?

If you miss a dose, take it as soon as you remember. However, if it's almost time for your next dose, skip the missed dose and continue with your regular schedule.

Last Updated On 09 Sep. 2026 | 7:04AM (IST)

Certified Content

Written by

Ashmita Borgohain

Medical Content Writer | 14 years

MSc (Applied Genetics)

Reviewed by

Dr. Divya Chauhan

Medical Content Writer & Reviewer | 8 years

BAMS, APG, PG

Check out Editorial Policy

Manufacturer details

India

Country of origin: INDIA

Expiry on or after: January 2027

In case of any issues, contact us:

support@truemeds.in|09240250346

Address: 6th floor, Urmi Corporate Park Solaris, Saki Vihar Road, Andheri East, Mumbai 400071

References

Eisai Inc. & Pfizer Inc. (n.d.). ARICEPT® (donepezil hydrochloride) tablets and ARICEPT® ODT (donepezil hydrochloride) orally disintegrating tablets [Prescribing information]. U.S. Food and Drug Administration. Retrieved 1 April 2025, from https://www.accessdata.fda.gov/drugsatfda_docs/label/2006/020690s026,021720s003lbl.pdf
U.S. Food and Drug Administration. (2005). Namenda® (memantine hydrochloride) tablets/oral solution [Prescribing information] (NDA 21-627). Retrieved 1 April 2025, from https://www.accessdata.fda.gov/drugsatfda_docs/label/2005/021627lbl.pdf
Donepezil: Uses, Interactions, Mechanism of Action – DrugBank https://go.drugbank.com/drugs/DB00843
Memantine: Uses, Interactions, Mechanism of Action – DrugBank https://go.drugbank.com/drugs/DB01043
Govind N. (2020). Donepezil for dementia due to Alzheimer's disease. British journal of community nursing, 25(3), 148–149. https://doi.org/10.12968/bjcn.2020.25.3.148

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Disclaimer

We, at Truemeds make a diligent attempt to deliver accurate, expert- drafted and thoroughly reviewed medicine related information to our consumers. However, it should, by no means, be considered a substitute for prescription from a certified doctor or a trustworthy doctor-patient relationship. In fact we detest any form of self medication without expert advice. The sole purpose of the information on our portal is to educate our consumers, which helps improve the communication between a doctor and a patient. The information by no means is complete in its entirety and should not be used to diagnose or treat any medical condition. No amount of information can replace the experience and expertise of a doctor, therefore his/her advice always holds priority and should be followed appropriately.

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