Afec P 100/325 MG Tablet 10

Mestra Pharma Pvt Ltd

Pack of 10 Units

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Prescription required for this medicine

Store Below 30^o C

Composition

Aceclofenac (100 Mg) + Paracetamol/acetaminophen (325 Mg)

Afec P 100/325 MG Tablet 10 is used to manage pain and inflammation caused by arthritis, muscle injuries, and post-surgical recovery. It helps reduce swelling, stiffness, and discomfort, improving joint movement and physical activity. This medicine is also effective in relieving musculoskeletal pain and inflammation from daily strain or injury. Regular use supports better mobility and comfort. Take it exactly as prescribed and inform your doctor about stomach issues, kidney problems, or other pain medicines before starting treatment.

Afec P 100/325 MG Tablet 10 is used to relieve pain, inflammation, and fever associated with headaches, toothaches, menstrual cramps, arthritis, and minor injuries. It also helps ease body aches linked to cold, flu, and physical strain.

Use Afec P 100/325 MG Tablet 10 following these instructions:

Swallow the tablet whole with a glass of water.
Avoid breaking, chewing, or crushing the tablet.
Always follow the recommended dose provided by your doctor.
Consult your doctor before altering the dose or stopping the medicine.

Afec P 100/325 MG Tablet 10 is taken orally.

Afec P 100/325 MG Tablet 10 may cause side effects such as nausea, vomiting, stomach pain, diarrhea, constipation, indigestion, low appetite, dizziness, headache, sleepiness, and fatigue. Consult your doctor if these side effects become troublesome.

Managing the Side Effects:

Afec P 100/325 MG Tablet 10 may cause common side effects such as nausea, vomiting, stomach pain, diarrhea, constipation, loss of appetite, indigestion, dizziness, headache, or feeling sleepy. Most of these effects are mild and usually go away on their own.

Afec P 100/325 MG Tablet 10 consists of two active ingredients that work together to provide relief from pain and inflammation:

Aceclofenac (100 mg): It is an NSAID that inhibits the cyclooxygenase-2 enzyme, which is involved in the production of prostaglandins. These chemical messengers are key to inflammation, pain, and fever. By blocking the action of cyclooxygenases-2 enzyme, aceclofenac reduces the inflammation, pain, and fever associated with musculoskeletal disorders, joint pain, and injuries.
Paracetamol/Acetaminophen (325 mg): Believed to act mainly on the central nervous system, acetaminophen inhibits central prostaglandin production by blocking COX enzymes in the brain. It increases the pain threshold and brings down fever by acting on the brain's heat-regulating centre.

Pregnancy

Afec P 100/325 MG Tablet 10 is contraindicated during the third trimester of pregnancy. If you are pregnant or planning to conceive, discuss this with your doctor.

Breastfeeding

Caution is advised while taking Afec P 100/325 MG Tablet 10 if you are breastfeeding. Be sure to consult your doctor to understand the potential risks and benefits.

Alcohol

Drinking alcohol while taking Afec P 100/325 MG Tablet 10 can increase the risk of gastrointestinal bleeding and liver damage. It's best to avoid alcohol when using this medicine.

Liver

This medicine should be used with caution if you have liver problems. Afec P 100/325 MG Tablet 10 is not recommended for severe liver diseases. Discuss your liver health with your doctor before starting this medication.

Kidney

If you have any kidney issues, it's advised to consult your doctor before using Afec P 100/325 MG Tablet 10. Careful monitoring is necessary during the course of the medication.

Using Machines & Driving

Afec P 100/325 MG Tablet 10 may cause dizziness or sleepiness. It's advisable not to drive or operate heavy machinery until you know how this medicine affects you.

Allergy

If you're allergic to aceclofenac, paracetamol, or any other ingredients in Afec P 100/325 MG Tablet 10, avoid taking this medicine. Allergic reactions may include swelling of the face, throat or tongue.

Children

Caution is advised while giving Afec P 100/325 MG Tablet 10 to children under 18 years of age. Always consult your doctor before giving this medicine to a child.

Older Patients

Older patients should take Afec P 100/325 MG Tablet 10 under medical supervision as they may be more susceptible to its side effects. If you are above 70 years old or have liver and kidney issues, it's important to consult your doctor before starting this medication.

Drug-Drug Interactions

Afec P 100/325 MG Tablet 10 interacts with the following medicines:

Non-Steroidal Anti-Inflammatory Drugs (NSAIDs): When taken with Afec P 100/325 MG Tablet 10, other NSAIDs like ibuprofen and naproxen may increase the risk of gastrointestinal ulceration and bleeding.
Anticoagulants: Medications such as warfarin may interact with Afec P 100/325 MG Tablet 10, enhancing the anticoagulant effect and increasing the risk of bleeding.
Antihypertensives: Medicines like amlodipine or lisinopril, taken alongside Afec P 100/325 MG Tablet 10, may have their blood pressure-lowering effects reduced.
Diuretics: like chlorothiazide and chlorthalidone may interact with this tablet and increase the risk of nephrotoxicity.
Quinolone Antibiotics: When combined with Afec P 100/325 MG Tablet 10, antibiotics like ciprofloxacin or levofloxacin may heighten the risk of seizures.

Drug-Food Interactions

There are no significant food interactions with Afec P 100/325 MG Tablet 10.

Drug-Disease Interactions

Afec P 100/325 MG Tablet 10 interacts with the following diseases:

Gastrointestinal Bleeding: Afec P 100/325 MG Tablet 10 could exacerbate gastrointestinal bleeding and conditions such as peptic ulcers due to its potential to irritate the stomach lining.
Asthma: Individuals with aspirin-sensitive asthma could experience worsened symptoms when taking Afec P 100/325 MG Tablet 10.
Kidney Issues: If you have kidney problems, taking this medicine might lead to increased side effects.
Liver Dysfunction: This medicine's metabolisation process might be affected in people with liver issues, potentially leading to increased side effects.
Hypertension: As NSAIDs can lead to fluid retention, Afec P 100/325 MG Tablet 10 could pose risks for those with high blood pressure.
Heart Disease: People with heart disease should be cautious while taking this medicine since it could increase their risk of heart problems.

Daily Dose

The dosage of Afec P 100/325 MG Tablet 10 varies based on individual factors including your condition's severity and your response to the medicine. Always adhere to the dosage prescribed by your doctor. Never exceed this dosage without your doctor's advice.

Over Dose

Common symptoms of overdose may include nausea, vomiting, and sleepiness. If you suspect an overdose, it's important to inform your doctor. Do not ignore these symptoms as they might worsen over time.

Missed Dose

If you miss a dose of Afec P 100/325 MG Tablet 10, take it as soon as you recall it. However, if it's nearly time for your next dose, skip the missed one and maintain your regular schedule. Always remember, never adjust your dosage without consulting your doctor.

Store Afec P 100/325 MG Tablet 10 below 30°C in a dry place.
Keep it away from direct sunlight and moisture.
Keep it out of the reach of children for safety.
Ensure you use the tablet before the expiry date printed on its pack.

If you are taking Afec P 100/325 MG Tablet 10 for joint pain conditions like osteoarthritis, incorporate foods rich in omega-3 fatty acids such as fish, walnuts, and chia seeds into your diet. Omega-3 fats help reduce inflammation.
Regular, gentle exercises like walking or swimming can help manage pain and improve joint mobility. Consult your doctor before starting any new exercise regimen.

Fact Box

Available Dosage Types	Tablet
Habit Forming	No
Ailment	Osteoarthritis, Rheumatoid arthritis, Ankylosing spondylitis
Drug Category	NSAIDs, Analgesics
Therapeutic Category	Analgesic, Anti-inflammatory

What is Afec P 100/325 MG Tablet 10 used for?

Afec P 100/325 MG Tablet 10 is used to relieve pain, swelling, and inflammation caused by conditions such as muscle injury, arthritis, and sprains. It helps reduce fever and eases discomfort linked to headaches, toothaches, and joint pain. The tablet also improves mobility by lowering pain and stiffness.

How does Afec P 100/325 MG Tablet 10 work?

This tablet contains aceclofenac and paracetamol, which work together to reduce pain, swelling, and inflammation.

How should I take Afec P 100/325 MG Tablet 10?

You should take the tablet orally with or without food, as advised by your doctor.

Are there any side effects of taking Afec P 100/325 MG Tablet 10?

You may experience nausea, stomach pain, diarrhoea, dyspepsia, or dizziness, among others. If these are severe or persistent, consult your doctor.

Can I take Afec P 100/325 MG Tablet 10 on an empty stomach?

It's best to take this medicine after meals to reduce the risk of stomach irritation.

What if I forget to take a dose of Afec P 100/325 MG Tablet 10?

Take the missed dose as soon as you remember, but skip it if it's nearly time for the next dose.

Can I take other medicines while taking Afec P 100/325 MG Tablet 10?

Tell your doctor about all other medicines you are using, as some medications may interact with Afec P 100/325 MG Tablet 10.

Last Updated On 16 Jan. 2026 | 10:13AM (IST)

Certified Content

Written by

Ashmita Borgohain

Medical Content Writer | 13 years

MSc (Applied Genetics)

Reviewed by

Dr. Chhavi Rosha

Medical Content Writer | 9 years

BAMS, FMC, MD Resident

Check out Editorial Policy

Manufacturer details

MESTRA PHARMA PVT LTD, 68, SOMNATH SOCIETY, KRISHNA NAGAR, AHMEDABAD, GUJRAT-382346

Expiry on or after: May 2026

In case of any issues, contact us:

support@truemeds.in|09240250346

Address: 6th floor, Urmi Corporate Park Solaris, Saki Vihar Road, Andheri East, Mumbai 400071

References

National Center for Biotechnology Information. (2021). The Analgesic Effect of Paracetamol, NSAIDs, and Their Combination: A Literature Review. Retrieved 1 April 2024, from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8643213/
U.S. National Library of Medicine. (2022). Acetaminophen: MedlinePlus Drug Information. Retrieved 1 April 2024, from https://medlineplus.gov/druginfo/meds/a681004.html
U.S. National Library of Medicine. (2021). CLANZA CR- aceclofenac tablet, film coated
: DailyMed Drug Information. Retrieved 1 April 2024, from https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=8a023942-01e8-4849-aa3c-1a640ffc7fd3
Rwanda Food and Drug Authority. (2022). Dolowin 100 (Aceclofenac) Film Coated Tablet: Summary of Product Characteristics. Retrieved 1 April 2024, from https://rwandafda.gov.rw/wp-content/uploads/2022/11/DOLOWIN_100__ACECLOFENAC__FILM_COATED_TABLET-SMPC.pdf
U.S. Food and Drug Administration. (2018). Information by Drug Class Acetaminophen. Retrieved 1 April 2024, from https://www.fda.gov/drugs/information-drug-class/acetaminophen

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We, at Truemeds make a diligent attempt to deliver accurate, expert- drafted and thoroughly reviewed medicine related information to our consumers. However, it should, by no means, be considered a substitute for prescription from a certified doctor or a trustworthy doctor-patient relationship. In fact we detest any form of self medication without expert advice. The sole purpose of the information on our portal is to educate our consumers, which helps improve the communication between a doctor and a patient. The information by no means is complete in its entirety and should not be used to diagnose or treat any medical condition. No amount of information can replace the experience and expertise of a doctor, therefore his/her advice always holds priority and should be followed appropriately.

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