CompositionAcinimide P 100/500 MG Tablet 10 is used for the short-term relief of acute pain and inflammation, such as severe headaches, toothaches, and menstrual cramps. It is also highly effective for reducing high fever and soothing the muscle aches associated with viral infections or joint injuries. By addressing both the source of pain and the body's temperature regulation, it provides rapid physical comfort.
This medication combines Nimesulide, a selective NSAID, and Paracetamol. Nimesulide targets the specific enzymes at the site of injury to reduce swelling and throbbing, while Paracetamol works on the central nervous system to elevate the pain threshold and lower fever. This dual-action formula is often more effective for inflammatory pain than single-ingredient alternatives.
Take this tablet after a meal to protect your stomach, as directed by your doctor. Due to the Nimesulide component, this medicine should be used for the shortest duration possible (typically not exceeding 10–15 days) to avoid liver strain. Avoid alcohol while taking this medication. Inform your doctor immediately if you notice dark urine or yellowing of the skin.
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Acinimide P 100/500 MG Tablet 10
Acinom Healthcare Pvt Ltd
Pack of 10 Units
Old MRP ₹27
MRP ₹25.31
₹20.25
₹2.53/Units
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About Acinimide P 100/500 MG Tablet 10
Uses of Acinimide P 100/500 MG Tablet 10
Acinimide P 100/500 MG Tablet 10 is used for managing pain from headaches and migraines, discomfort associated with toothache and dental procedures, musculoskeletal pain (e.g., osteoarthritis, rheumatoid arthritis), dysmenorrhoea (painful menstruation), post-operative pain, and fever caused by infections. This combination (Nimesulide + Paracetamol) provides dual-action analgesic and antipyretic relief.
Directions for Use of Acinimide P 100/500 MG Tablet 10
- Swallow the tablet whole with a glass of water.
- Avoid crushing or chewing the tablet, as it may impact its effectiveness.
- It is recommended to take this medicine with food or milk to prevent any gastric discomfort.
- Never exceed the recommended dose without consulting your doctor.
- If you have any doubts about using this medicine, consult your doctor for further advice.
Route of Administration
Acinimide P 100/500 MG Tablet 10 is taken orally.
Side Effects of Acinimide P 100/500 MG Tablet 10
Acinimide P 100/500 MG Tablet 10 may cause side effects like nausea, vomiting, stomach pain, diarrhoea, constipation, dizziness, headache, or skin rash. If these side effects persist or worsen, consult your doctor.
Management Of Side Effects:
Most side effects are temporary and generally harmless, which resolve upon discontinuing the use of Acinimide P 100/500 MG Tablet 10. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.
How Acinimide P 100/500 MG Tablet 10 Works?
Acinimide P 100/500 MG Tablet 10 contains two active components which work together:
- Nimesulide (100 mg): This component is a selective COX-2 inhibitor. It works by reducing inflammation and pain through inhibiting an enzyme named cyclooxygenase-2 (COX-2). This enzyme produces prostaglandins, chemicals that cause inflammation in the body. By inhibiting COX-2 selectively, nimesulide relieves pain and inflammation with fewer gastrointestinal side effects.
- Paracetamol (500 mg): Known for its analgesic and antipyretic properties, paracetamol helps relieve pain and reduce fever. It inhibits prostaglandin synthesis in the central nervous system (CNS). Additionally, it appears to act on the serotonergic pathways that regulate body temperature.
Safety Measures & Warnings
Pregnancy
Acinimide P 100/500 MG Tablet 10 should not be taken during the third trimester of pregnancy. If you are pregnant or planning to conceive, it is best to consult your doctor before taking this medicine.
Breastfeeding
Acinimide P 100/500 MG Tablet 10 is warned against use for breastfeeding women. Discussing this with your doctor to understand the potential risks and benefits is recommended.
Alcohol
Avoid or limit alcohol while taking this medicine, as alcohol can increase the risk of liver damage, especially with regular or high alcohol intake.
Liver
If you have any liver problems, caution is advised while taking this tablet. This medicine is not recommended for severe liver diseases as it may affect liver function. Discuss this with your doctor before starting the medication.
Kidney
If you have a history of kidney problems, it is a good idea to consult your doctor before taking Acinimide P 100/500 MG Tablet 10.
Use In Driving And Operating Machinery
Acinimide P 100/500 MG Tablet 10 may cause drowsiness or dizziness. Avoid driving or operating heavy machinery until you know how this medicine affects you.
Allergy
Acinimide P 100/500 MG Tablet 10 should not be used if you are allergic to nimesulide, paracetamol, or other NSAIDs. If you have a history of allergic reactions to these substances, consult your doctor before taking this medicine.
Children
Acinimide P 100/500 MG Tablet 10 is not recommended for children under 12 years of age. Always consult your doctor before giving this medicine to a child.
Older Patients
Elderly patients should take Acinimide P 100/500 MG Tablet 10 under medical supervision as they may be more susceptible to its side effects. Caution is advised if patients are above 70 years of age. Your doctor will guide you based on your health status.
Interactions of Acinimide P 100/500 MG Tablet 10
Drug-Drug Interactions
Acinimide P 100/500 MG Tablet 10 may interact with the following medicines:
- Anticoagulants like warfarin can increase the risk of bleeding when taken with Acinimide P 100/500 MG Tablet 10.
- Antihypertensives such as amlodipine or lisinopril may have decreased efficacy when used concurrently with Acinimide P 100/500 MG Tablet 10.
- Diuretics like furosemide or hydrochlorothiazide with this medicine can heighten the risk of kidney dysfunction.
- Mood stabilising medicines such as lithium when taken with Acinimide P 100/500 MG Tablet 10 could cause an increase in its levels, leading to toxicity.
- Antimetabolites such as methotrexate: Methotrexate's levels and its toxicity may be raised when used along with this medication.
- Nucleoside analogue reverse-transcriptase inhibitors (NRTIs) such as zidovudine when combined with Acinimide P 100/500 MG Tablet 10 increases the risk of blood toxicity.
Drug-Food Interactions
There are no specific food interactions identified with Acinimide P 100/500 MG Tablet 10.
Drug-Disease Interactions
Acinimide P 100/500 MG Tablet 10 can interact with the following diseases:
- Liver Disease: This medicine might exacerbate your condition if you have severe liver impairment.
- Renal Impairment: Those with severe kidney disease should use Acinimide P 100/500 MG Tablet 10 cautiously as it could worsen renal function.
- Heart Failure or Coronary Artery Disease: Patients suffering from these conditions should be aware that this medication might heighten risks associated with their heart condition.
Dosage of Acinimide P 100/500 MG Tablet 10
Daily Dose
The daily dose of Acinimide P 100/500 MG Tablet 10 should be as recommended by your doctor. This may vary depending on your response to treatment and how severe your condition is. Sticking to the prescribed dosage and not going beyond it without consulting your doctor is crucial.
Over Dose
In case of an accidental overdose, you might experience common side effects like nausea or dizziness in a more intense way. In such cases, it's important to inform your doctor right away.
Missed Dose
If you forget to take a dose of Acinimide P 100/500 MG Tablet 10, take it as soon as you remember. However, if it's nearly time for your next dose, skip the one you missed and continue with your regular dosage schedule. Never alter your dosage without talking to your doctor first.
Storage
- Keep Acinimide P 100/500 MG Tablet 10 in a cool, dry place at room temperature.
- Avoid direct sunlight or moist environments to prevent the degradation of the medicine.
- Place the medicine out of sight and reach of children to avoid accidental consumption.
- Ensure you use the tablet before its expiry date for maximum efficacy.
Special Dietary And Lifestyle Recommendation
- Maintain a balanced diet rich in omega-3 fatty acids found in fish and flaxseeds to help manage inflammation.
- Regular gentle exercises such as swimming or walking can aid mobility and reduce pain associated with these conditions. Always consult your doctor before starting any new exercise regimen.
Fact Box
| Dosage Forms Available | Tablet |
| Habit Forming | No |
| Ailment | Headache, Fever, Musculoskeletal pain |
| Drug Category | COX-2 inhibitor |
| Therapeutic Category | Analgesic, Antipyretic |
Frequently Asked Questions (FAQs)
What is Acinimide P 100/500 MG Tablet 10 used for?
Acinimide P 100/500 MG Tablet 10 manages mild to moderate pain, such as headaches, toothaches, menstrual pain, and post-operative discomfort. It also helps reduce fever caused by infections.
How does Acinimide P 100/500 MG Tablet 10 work?
This medicine combines nimesulide and paracetamol. Nimesulide decreases inflammation and pain by blocking a specific enzyme, while paracetamol reduces pain and fever by affecting the central nervous system.
Can I take Acinimide P 100/500 MG Tablet 10 on an empty stomach?
No, taking the medicine with food or milk helps avoid stomach discomfort. If you still experience gastric irritation, consult your doctor about it.
Is it safe to use Acinimide P 100/500 MG Tablet 10 for prolonged periods?
No, unsupervised use of this medicine over 15 days can cause serious side effects. Always consult your doctor before using it for a long time.
What should I do if I miss a dose of Acinimide P 100/500 MG Tablet 10?
Take the missed dose as soon as you remember. However, if it's nearly time for your next dose, skip the missed one. Never double your dose.
Can I consume alcohol while taking Acinimide P 100/500 MG Tablet 10?
Avoid or limit alcohol while taking this medicine, as alcohol can increase the risk of liver damage, especially with regular or high alcohol intake.
Can I take other painkillers along with Acinimide P 100/500 MG Tablet 10?
Avoid taking any other medication containing paracetamol or non-steroidal anti-inflammatory drugs (NSAIDs) along with this medicine to prevent overdosage. Always consult your doctor before combining medications.
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References
- MedlinePlus. (n.d.). Acetaminophen. Retrieved from https://medlineplus.gov/druginfo/meds/a681004.html
- U.S. Food and Drug Administration. (2006). Labeling-Package Insert. Retrieved from https://www.accessdata.fda.gov/drugsatfda_docs/label/2006/040330s015,040341s013,040434s003lbl.pdf
- Rainsford, K. D., & Whitehouse, M. W. (1983). Paracetamol (acetaminophen) metabolism in the rat. Agents and actions, 13(4), 360–368. Retrieved from https://pubmed.ncbi.nlm.nih.gov/6354603/
- DailyMed - ACETAMINOPHEN tablet. (n.d.). https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=c3b408ff-f47b-4fee-ade5-5db6e25f4ee0
- Acetaminophen: Uses, Interactions, Mechanism of Action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB00316
Disclaimer
We, at Truemeds make a diligent attempt to deliver accurate, expert- drafted and thoroughly reviewed medicine related information to our consumers. However, it should, by no means, be considered a substitute for prescription from a certified doctor or a trustworthy doctor-patient relationship. In fact we detest any form of self medication without expert advice. The sole purpose of the information on our portal is to educate our consumers, which helps improve the communication between a doctor and a patient. The information by no means is complete in its entirety and should not be used to diagnose or treat any medical condition. No amount of information can replace the experience and expertise of a doctor, therefore his/her advice always holds priority and should be followed appropriately.
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