Top 10 Antifungal Creams in India: Effective Treatments for Fungal Infections

You may think it’s “just an itch.” But for millions of people in India, that persistent redness or rash on the skin is a fungal infection, and it’s not going away on its own.

Thanks to India’s warm, humid climate and densely populated cities, skin fungal infections (like ringworm, athlete’s foot, and jock itch) are among the most common dermatological complaints. Fungal skin infections currently affect an estimated 20% to 25% of the population. They account for 10% to 20% of all skin diseases, making them one of the most common conditions that dermatologists see in their practice.

The key to proper treatment? Use the right antifungal cream consistently and correctly. In this guide, we break down the top antifungal creams in India, how they work, and how to choose the one that’s best for your skin.

How Antifungal Creams Work

Antifungal creams are specifically formulated to target and eliminate fungal infections through several mechanisms:

• Inhibiting fungal growth by preventing the fungi from multiplying and spreading
• Killing fungal cells by destroying their cell membranes
• Reducing inflammation, redness, and itching associated with fungal infections
• Maintaining skin health with additional ingredients that hydrate and nourish the skin

How to Choose the Best Cream for Fungal Infections

When selecting an antifungal cream, it is essential to consider several factors to ensure you choose the most effective and suitable option for your specific needs. Firstly, opt for a cream that is clinically tested and recommended by dermatologists, as this ensures its safety and efficacy. Secondly, look for creams containing active ingredients that target the specific type of fungal infection you have, such as ketoconazole for broad-spectrum antifungal activity or clotrimazole for treating yeast infections. Additionally, consider the cream’s suitability for your skin type and any potential side effects to minimise the risk of adverse reactions. Reading reviews and seeking advice from a healthcare professional can help you make an informed decision when choosing the best antifungal cream for your needs.

10 Best Creams for Fungal Infections

When it comes to treating fungal infections effectively, selecting the right antifungal cream is crucial. Here are the top 10 formulations available in India, each with its unique set of active ingredients and benefits:

1. Clotrimazole
2. Miconazole Nitrate
3. Ofloxacin, Itraconazole, Clobetasol, and Ornidazole
4. Ketoconazole
5. Sertaconazole
6. Benzyl Alcohol and Terbinafine Hydrochloride
7. Beclomethasone dipropionate, Neomycin sulphate, and Clotrimazole
8. Mometasone, Miconazole, and Nadifloxacin
9. Itraconazole, Ofloxacin, Clobetasol Propionate, and Ornidazole
10. Eberconazole

1. Clotrimazole

Clotrimazole is a powerful antifungal agent that effectively treats a wide range of fungal infections, such as ringworm, jock itch, and athlete’s foot. By inhibiting the synthesis of ergosterol, a crucial component of the fungal cell membrane, clotrimazole prevents fungal growth and alleviates symptoms such as itching, redness, and flaking. This active ingredient is quickly absorbed into the skin, providing rapid relief from the discomfort caused by fungal infections.

2. Miconazole Nitrate

Miconazole nitrate is another highly effective antifungal ingredient used to treat fungal skin infections, including ringworm, jock itch, and athlete’s foot. It works by killing the fungus causing the infection, providing fast relief from symptoms such as red, scaly rashes and itching. Miconazole nitrate is rapidly absorbed into the skin, making it an ideal choice for individuals seeking prompt and effective treatment for their fungal infections.

3. Combination of Ofloxacin, Itraconazole, Clobetasol, and Ornidazole

The combination of ofloxacin, itraconazole, clobetasol, and ornidazole is highly beneficial for treating various fungal skin infections. Ofloxacin acts as an antibiotic, while itraconazole targets fungal infections. Clobetasol reduces inflammation, and ornidazole helps in preventing bacterial infections. Together, these active ingredients provide comprehensive treatment for fungal and bacterial skin issues, minimising symptoms like itching, redness, and swelling.

4. Ketoconazole

Ketoconazole, a member of the imidazole-class antifungals, is effective in treating fungal infections such as pityriasis (tinea versicolor), ringworm, and athlete’s foot. It works by killing fungi and preventing their growth, providing quick relief from irritation and itching. Ketoconazole also has a cooling effect on the skin, making it comfortable to use and soothing the affected area.

5. Sertaconazole

Sertaconazole is used to treat fungal infections of the skin, particularly those affecting the feet and toes, such as athlete’s foot and tinea pedis (ringworm). It inhibits the growth of infection-causing fungi, reducing irritation and itchiness while soothing the skin. Sertaconazole is an effective option for individuals seeking relief from fungal infections in sensitive areas, such as the feet.

6. Benzyl Alcohol and Terbinafine Hydrochloride

The combination of benzyl alcohol and terbinafine hydrochloride is effective in treating skin infections, such as ringworm and athlete’s foot. Benzyl alcohol helps prevent fungal growth, while terbinafine hydrochloride kills the fungus by creating holes in its cell membrane. This combination relieves symptoms such as redness, itching, and irritation, making it a popular choice for those dealing with stubborn fungal infections.

7. Beclomethasone dipropionate, neomycin sulphate, and Clotrimazole

The combination of beclomethasone dipropionate, neomycin sulphate, and clotrimazole is used to treat fungal and bacterial skin infections. Beclomethasone dipropionate reduces inflammation, neomycin sulphate acts as an antibiotic, and clotrimazole targets fungal infections. Together, these active ingredients provide comprehensive treatment for infections like ringworm, jock itch, and athlete’s foot, alleviating symptoms such as itching, redness, and swelling.

8. Mometasone, Miconazole, and Nadifloxacin

The combination of mometasone, miconazole, and nadifloxacin effectively treats skin infections with swelling, itching, and redness. Mometasone reduces inflammation by preventing white blood cells from reaching the affected area, while miconazole and nadifloxacin kill fungi by creating holes in their cell membranes. This combination provides rapid relief from fungal infections and reduces symptoms like itching and redness.

9. Itraconazole, Ofloxacin, Clobetasol Propionate, and Ornidazole

The combination of itraconazole, ofloxacin, clobetasol propionate, and ornidazole is beneficial for treating skin fungal infections. Itraconazole targets fungal infections, ofloxacin acts as an antibiotic, clobetasol propionate reduces inflammation, and ornidazole helps prevent bacterial infections. Together, these active ingredients minimise symptoms like itching, redness, and swelling and block the release of chemicals that cause these symptoms.

10. Eberconazole

Eberconazole is a topical antimicrobial cream used to treat dermatophytoses, candidiasis, and pityriasis. It stops fungal growth by preventing the formation of fungal protective coverings, relieving symptoms such as cracking, burning, scaling, and itching of the skin caused by infections. Eberconazole is an effective choice for those seeking targeted treatment for specific fungal skin conditions.

How to Apply Anti-Fungal Cream Correctly

To ensure the effective treatment of fungal infections, it is essential to apply anti-fungal creams correctly. Follow these key pointers for optimal results:

• Wash your hands thoroughly before and after applying the cream to prevent the spread of the infection.
• Gently clean the infected area with soap and water before applying the cream.
• Apply the cream directly to the affected area, avoiding contact with the eyes, nose, ears, or mouth.
• Use the cream as directed by your doctor or according to the package instructions, typically applying a thin layer 1-3 times a day.
• Do not apply more cream than recommended, as this can lead to side effects such as skin irritation.
• Continue using the cream for the full recommended treatment period, even if symptoms improve before the treatment is complete.

Preventing Fungal Infections

Preventing fungal infections involves a combination of good hygiene practices and lifestyle adjustments. Here are some key points to consider:

• Maintain good hygiene by regularly washing your skin, especially after sweating, and drying it thoroughly, paying extra attention to areas prone to moisture like between the toes and in the groin area.
• Apply antifungal powders or sprays to vulnerable areas to help prevent infections.
• Choose clothing that allows air to circulate and helps keep skin dry.
• Avoid sharing personal items, such as towels, socks, or shoes, to prevent the spread of fungal spores.
• Keep public areas clean by avoiding walking barefoot in areas such as swimming pools, locker rooms, or showers, where fungal spores may be present.

Side Effects and Precautions When Using Fungal Creams

While antifungal creams are generally safe and effective, it is important to be aware of potential side effects and take necessary precautions:

• Skin irritation, such as burning, itching, or redness, may occur at the site of application.
• Some creams can cause dry skin or blistering.
• Avoid applying the cream near the eyes, nose, ears, and mouth, and rinse immediately if accidental contact occurs.
• Be vigilant for signs of allergic reactions, such as hives, swelling, or difficulty breathing, and seek medical help if they occur.
• Consult a doctor before using antifungal creams if you are pregnant or breastfeeding to ensure safety.

When to Switch from Topical to Oral Antifungals

Topical creams are effective for most mild to moderate fungal infections. However, if symptoms don’t improve within 2–4 weeks, or if the disease is widespread, deeply rooted, or keeps recurring, it’s time to consider oral antifungal medications. Drugs like fluconazole, itraconazole, or terbinafine tablets may be prescribed for more effective, systemic treatment. Always consult a doctor before switching to oral therapy.

When to Consult a Doctor

In certain situations, it is crucial to consult a healthcare professional when managing fungal infections. If the infection does not improve with over-the-counter treatments or if the symptoms worsen, consult a doctor. Additionally, if you notice signs of the infection spreading or have a weakened immune system, it is important to seek professional help. If you are unsure about the diagnosis or treatment of your fungal infection, it is always best to consult a doctor for an accurate assessment and appropriate treatment plan.

Final word: Choose wisely, treat early

Fungal infections may seem minor, but they can spread rapidly, itch relentlessly, and recur if not treated properly. Choosing the right antifungal cream—with the correct active ingredient and no harmful additives—is the first step toward lasting relief.

Applying them consistently, maintaining good hygiene, and knowing when to see a doctor are just as important.

Expert opinion

Don’t wait too long to treat fungal infections. The earlier you start the right treatment, the better your chances of complete recovery without recurrence. Avoid combination creams with steroids unless they’re prescribed—it’s one of the main reasons we’re seeing resistant cases today.

– Dr. Lakshmi Vaswani

Frequently Asked Questions (FAQs)

References

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2. Poojary, S. (2017). Topical antifungals: A review and their role in current management of dermatophytoses. Clinical Dermatology Review, 1(3), 24. https://doi.org/10.4103/cdr.cdr_34_17
3. Kyle, A. A., & Dahl, M. V. (2004). Topical therapy for fungal infections. American Journal of Clinical Dermatology, 5(6), 443–451. https://doi.org/10.2165/00128071-200405060-00009
4. Mijaljica, D., Spada, F., & Harrison, I. P. (2022). Emerging trends in the use of topical Antifungal-Corticosteroid combinations. Journal of Fungi, 8(8), 812. https://doi.org/10.3390/jof8080812
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