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Velpride Plus Capsule 10

Avis Life Care Pvt Ltd

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Composition

Levosulpiride (75 Mg) + Rabeprazole (20 Mg)

Velpride Plus Capsule is a combination medicine used to treat gastroesophageal reflux disease (GERD), acid reflux, and peptic ulcers. It provides effective relief from symptoms like heartburn, stomach pain, bloating, and indigestion.

It contains rabeprazole and levosulpiride. Rabeprazole reduces stomach acid production while levosulpiride improves stomach and bowel movement to prevent acid from flowing back up into the food pipe. Take it before meals as prescribed.

Eating smaller, regular meals, avoiding spicy and fatty foods, limiting caffeine and alcohol, and avoiding lying down immediately after meals help improve digestive comfort alongside this medicine.

Before taking this medicine, tell your doctor if you have severe kidney or liver problems, gastrointestinal bleeding, or bone density issues. Speak to your doctor if stomach pain or acid reflux symptoms do not improve after treatment.

Velpride Plus Capsule is used to manage acid-related digestive disorders, GERD, and peptic ulcers in adults.

Uses of Velpride Plus Capsule are:

Gastroesophageal Reflux Disease: Relieves heartburn, acid regurgitation, and chest discomfort.
Peptic Ulcer Support: Reduces stomach acid to support the healing of stomach and intestinal ulcers.
Indigestion and Gas Relief: Helps relieve abdominal bloating, fullness, and indigestion.

Here's how to properly take Velpride Plus Capsule 10:

Swallow the capsule whole with water.
It is advisable to take Velpride Plus Capsule 10 on an empty stomach, at least one hour before eating.
Do not chew, break, or open the capsule.
Always follow your doctor's instructions regarding the dosage of this medication.

Velpride Plus Capsule 10 is taken orally.

Velpride Plus Capsule may cause some side effects that are usually mild and go away as your body adjusts to the medicine.

A few common side effects of Velpride Plus Capsule:

Digestive: Feeling sick (nausea), vomiting, loose motions (diarrhoea), stomach pain, dry mouth, constipation, and gas.
Neurological: Headache, dizziness, drowsiness, and tiredness.

If side effects do not improve or become serious, speak to your doctor right away.

Management Of Side Effects:

Most side effects are temporary, generally mild, and resolve upon discontinuing the use of Velpride Plus Capsule 10. However, if you experience any serious side effects or worsening of any symptoms, notify your doctor.

Here are a few general guidelines to manage common side effects:

Nausea and vomiting: Taking Velpride Plus Capsule 10 with a meal may help lessen these effects.
Flatulence: Try taking this medicine at night if it causes you excessive gas during the day.

Velpride Plus Capsule 10 contains two active ingredients that work together to manage various gastrointestinal conditions:

Rabeprazole (20 mg): Rabeprazole acts on your stomach by decreasing the production of acid. It does this by irreversibly blocking an enzyme system known as H+/K+ ATPase present in your gastric parietal cells, also called proton pumps. Reduced acidity helps relieve symptoms of gastroesophageal reflux disease and allows oesophageal and stomach ulcers to heal.
Levosulpiride (75 mg): This component works in your body by stimulating the release of acetylcholine. Acetylcholine is a neurotransmitter that promotes contraction of the stomach muscles, helping to move food from the stomach into the small intestine efficiently.

Pregnancy

If you are pregnant or planning to conceive, caution is recommended while taking Velpride Plus Capsule 10. Always consult your doctor before starting this medication.

Breastfeeding

If you are breastfeeding, it's essential to discuss this with your doctor before taking Velpride Plus Capsule 10.

Alcohol

Avoid consuming alcohol while on this medication, as alcohol can trigger heartburn and acidity, exacerbating your condition.

Liver

If you have liver problems, caution is advised when you are prescribed Velpride Plus Capsule 10. Your doctor will evaluate if this medicine is appropriate for you.

Kidney

For those with kidney health concerns, it is advised to consult your doctor before taking Velpride Plus Capsule 10.

Use In Driving And Operating Machinery

Velpride Plus Capsule 10 may make you feel sleepy or lightheaded. It's best to wait until you know how the medication affects you before operating heavy machinery or driving.

Allergy

Velpride Plus Capsule 10 should not be taken if you have a history of hypersensitivity to levosulpiride, rabeprazole, or any other ingredient in the formulation.

Children

Exercise caution before giving Velpride Plus Capsule 10 to children. Always consult your doctor before giving any medication to a child.

Older Patients

Due to their potential increased susceptibility to side effects, older people should only take Velpride Plus Capsule 10 under medical supervision. Patients who are older than 70 years of age are urged to proceed with caution, especially if they have a history of kidney or liver disease or are on any other medications.

Drug-Drug Interactions

Velpride Plus Capsule 10 interacts with these medicines:

Antifungals: Medicines like ketoconazole may have reduced efficacy if taken with Velpride Plus Capsule 10, due to decreased stomach acidity.
Anticoagulants: The blood-thinning action of warfarin can be affected by Velpride Plus Capsule 10, potentially leading to altered blood clotting times.
Immunosuppressants: Medicines such as cyclosporine might interact with Velpride Plus Capsule 10, potentially causing changes in their therapeutic effect.
Antineoplastics: When used with Velpride Plus Capsule 10, levels of anti-cancer medicines like methotrexate can be increased, which might increase their toxicity.
Antiretrovirals: The effectiveness of medicines like atazanavir could be reduced when taken with Velpride Plus Capsule 10.
Antidepressants: Taking Velpride Plus Capsule 10 along with medicines like fluoxetine or sertraline might enhance the effects of these antidepressants.

Drug-Food Interactions

Velpride Plus Capsule 10 should preferably be taken on an empty stomach for optimal absorption. It has notable interactions with certain kinds of food:

High-fat meals: Consuming high-fat food might delay the absorption time of levosulpiride in Velpride Plus Capsule 10.

Drug-Disease Interactions

Velpride Plus Capsule 10 interacts with these diseases:

Liver disease: Patients with severe liver impairment should exercise caution as Velpride Plus Capsule 10 could potentially exacerbate their condition.
Kidney disease: Those suffering from severe kidney problems should be careful while taking Velpride Plus Capsule 10 as it may worsen their condition.
Osteoporosis: Long-term use of rabeprazole, one of the ingredients in Velpride Plus Capsule 10, may increase the risk of osteoporosis-related bone fractures.
Parkinson's disease: Levosulpiride in Velpride Plus Capsule 10 can exacerbate symptoms, as it blocks dopamine receptors.

Daily Dose

You should take the dose of Velpride Plus Capsule 10 as prescribed by your doctor. The dosage may vary depending on the severity of your condition and how you respond to the medicine. Always adhere to the prescribed dosage and never exceed it without consulting your doctor.

Over Dose

Overdosing on Velpride Plus Capsule 10 may result in side effects like drowsiness, confusion, tremors, sweating, vomiting, and a rapid heartbeat. If you suspect that you have taken too much of this medicine, inform your doctor right away.

Missed Dose

If you forget to take a dose of Velpride Plus Capsule 10, take it as soon as you remember. If it's nearly time for your next dose, skip the missed one and continue with your regular dosage schedule. Do not increase your dosage without consulting your doctor.

Store your Velpride Plus Capsule 10 at room temperature, ideally below 30 °C.
Protect it from direct sunlight, and excessive heat and moisture.
This medication should always be kept out of children's reach.
Ensure you use it before its expiration date.

Consume a diet high in fruits, vegetables, and whole grains, as well as other fibre-rich foods. This is beneficial in the management of symptoms related to GERD and IBS.
Limit your intake of fatty and spicy foods, as they can aggravate stomach acidity and worsen GERD symptoms.

Fact Box

Dosage Forms Available	Capsule
Habit Forming	No
Ailment	Gastroesophageal Reflux Disease, Intestinal Ulcers, Irritable Bowel Syndrome
Drug Category	Prokinetic Agent, Proton Pump Inhibitor
Therapeutic Category	Gastrointestinal Medicine

What is Velpride Plus Capsule 10 used for?

Irritable bowel syndrome (IBS), intestinal ulcers, and gastroesophageal reflux disease (GERD) are treated with Velpride Plus Capsule 10.

How does Velpride Plus Capsule 10 work?

This medicine contains levosulpiride, which encourages stomach muscular contraction for effective food movement, and rabeprazole, which lessens stomach acid production.

When should I take Velpride Plus Capsule 10?

It is best taken on an empty stomach, at least one hour before a meal. Always follow the advice of your doctor.

Can I crush or chew Velpride Plus Capsule 10?

No, the capsule should be swallowed whole with water. Don't crush, chew, or open it.

What precautions should I take while using Velpride Plus Capsule 10?

Inform your doctor if you have liver or kidney problems, are pregnant, planning pregnancy, or are breastfeeding before starting this medication.

Can Velpride Plus Capsule 10 interact with other medicines?

Yes, it may interact with certain medications, such as ketoconazole, warfarin, and cyclosporine. Always consult your doctor before taking other medicines.

What are the side effects of Velpride Plus Capsule 10?

Common side effects include nausea, vomiting, diarrhoea, and headaches. If any severe symptoms occur, seek immediate medical attention.

Last Updated On 18 Sep. 2026 | 10:06AM (IST)

Certified Content

Written by

Dr. Michelle Frank

Medical Content Writer | 10 years

Doctor of Medicine

Reviewed by

Dr. Osama Ahmed

Medical Content Writer | 4 years

Bachelor of Dental Surgery

Check out Editorial Policy

Manufacturer details

117-A,PADMAWATI COLONY-I, KINGS ROAD JAIPUR RJ 302019 IN

Country of origin: INDIA

Expiry on or after: February 2027

In case of any issues, contact us:

support@truemeds.in|09240250346

Address: 6th floor, Urmi Corporate Park Solaris, Saki Vihar Road, Andheri East, Mumbai 400071

References

U.S. Food and Drug Administration. (2014, Dec). Aciphex tablet label. https://www.accessdata.fda.gov/drugsatfda_docs/label/2014/020973s035204736s005lbl.pdf
U.S. Food and Drug Administration. (2013, Mar 5). Rabeprazole clinical review. https://www.fda.gov/media/85860/download
DrugBank Online. (2024, May 27). Rabeprazole. https://go.drugbank.com/drugs/DB01129
DrugBank Online. (2021, May 5). Levosulpiride. https://go.drugbank.com/drugs/DB16021
Lozano, R., Concha, M. P., Montealegre, A., de Leon, L., Villalba, J. O., Esteban, H. L., Cromeyer, M., García, J. R., Brossa, A., Lluberes, G., Sandí, E. I., & Quirós, H. B. (2007). Effectiveness and safety of levosulpiride in the treatment of dysmotility-like functional dyspepsia. Therapeutics and clinical risk management, 3(1), 149–155. https://doi.org/10.2147/tcrm.2007.3.1.149

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We, at Truemeds make a diligent attempt to deliver accurate, expert- drafted and thoroughly reviewed medicine related information to our consumers. However, it should, by no means, be considered a substitute for prescription from a certified doctor or a trustworthy doctor-patient relationship. In fact we detest any form of self medication without expert advice. The sole purpose of the information on our portal is to educate our consumers, which helps improve the communication between a doctor and a patient. The information by no means is complete in its entirety and should not be used to diagnose or treat any medical condition. No amount of information can replace the experience and expertise of a doctor, therefore his/her advice always holds priority and should be followed appropriately.

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Intellihealth Solutions Private Limited

Unit-301 & 304, Lightbridge Tunga Village, Saki Vihar Rd, Chandivali, Powai, Mumbai, Maharashtra, India, 400072.

CIN: U62099MH2019PTC320566

Telephone:09240250346

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Name: Kishor Kumar

Email: grievance-officer@truemeds.in

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