Simvastol 20mg Tablet 25

Themis Medicare Ltd.

Strip of 25 Units

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MRP ~~₹75.72~~

₹60.58

₹3.03/Units

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Prescription required for this medicine

Store Below 30^o C

Composition

Simvastatin (20 Mg)

Strength:

5 MG 20 MG

Simvastol 20mg Tablet 25 is used to lower high cholesterol levels in the blood, potentially reducing the risk of heart disease and stroke. It belongs to a class of medications known as statins, specifically HMG-CoA reductase inhibitors.

In addition to managing primary hypercholesterolaemia, this medicine also helps reduce triglyceride levels and increase HDL (good) cholesterol in the blood. It can be particularly beneficial for patients with coronary heart disease, diabetes, or those with familial hypercholesterolaemia, a genetic condition that causes very high cholesterol levels.

Take this medicine as directed by your doctor. Before starting this medicine, inform your doctor about any pre-existing conditions and any other medicines you are currently taking. If you notice any side effects while using this medicine, contact your doctor immediately. Continue taking the medicine for the duration prescribed by your doctor for optimal results.

Simvastol 20mg Tablet 25 is used for the following:

Lowering high cholesterol levels
Preventing heart attacks in at-risk patients
Reducing stroke risk in vulnerable individuals
Managing coronary heart disease
Helping patients with diabetes control cholesterol
Treating primary hypercholesterolaemia
Managing mixed dyslipidaemia alongside a proper diet
Controlling familial hypercholesterolaemia

Follow these instructions while taking Simvastol 20mg Tablet 25:

Swallow the tablet whole with a glass of water.
Do not crush, chew, or break the tablet.
You may take it with or without food.
Continue taking this medicine regularly even if you feel well.

Simvastol 20mg Tablet 25 is taken orally.

Simvastol 20mg Tablet 25 may have the following common side effects:

Headache
Nausea
Constipation
Abdominal pain
Diarrhoea
Myalgia: Muscle pain or aching, which might feel like soreness or tenderness in your muscles

Managing the Side Effects:

Most side effects are temporary and generally harmless, which resolve on discontinuing the use of Simvastol 20mg Tablet 25. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

Here are some ways to manage common side effects:

Nausea: Taking Simvastol 20mg Tablet 25 with your evening meal may help reduce feelings of nausea.
Abdominal pain: Try taking this medicine after dinner rather than on an empty stomach to lessen stomach discomfort.

Simvastol 20mg Tablet 25 contains Simvastatin (20 mg), which works on the body as follows:

Inhibits HMG-CoA Reductase: Simvastatin blocks an enzyme in your liver called HMG-CoA reductase, which is responsible for producing cholesterol in your body, resulting in lower overall cholesterol production.
Reduces LDL Cholesterol: By inhibiting cholesterol production, simvastatin helps lower the levels of low-density lipoprotein (LDL) or "bad" cholesterol in your bloodstream.
Increases HDL Cholesterol: The medicine helps raise the levels of high-density lipoprotein (HDL) or "good" cholesterol, which helps remove other forms of cholesterol from your bloodstream.
Enhances Liver Function: Simvastatin improves your liver's ability to remove existing LDL cholesterol from your blood, further contributing to reduced cholesterol levels.

Pregnancy

Simvastol 20mg Tablet 25 is contraindicated during pregnancy. If you are pregnant or planning to conceive, make sure to discuss this with your doctor before starting this medicine.

Breastfeeding

Simvastol 20mg Tablet 25 is contraindicated for breastfeeding women. Consult your doctor to understand the potential risks and benefits.

Alcohol

Avoid consuming alcohol while taking Simvastol 20mg Tablet 25. Alcohol may increase the risk of liver problems when combined with this medicine.

Liver

Caution is advised while taking Simvastol 20mg Tablet 25 in case of mild to moderate liver impairment. It is contraindicated for severe liver diseases. If you have liver problems, discuss them with your doctor before starting Simvastol 20mg Tablet 25.

Kidney

Caution is advised before using Simvastol 20mg Tablet 25 if you have a history of kidney problems. Consult your doctor before taking this medicine.

Using Machines & Driving

You may experience headaches or dizziness when taking Simvastol 20mg Tablet 25. If you notice these effects, avoid driving or operating heavy machinery until you feel better.

Allergy

If you have had allergic reactions to simvastatin or any other ingredients in Simvastol 20mg Tablet 25 in the past, do not take this medicine. Inform your doctor about all your allergies before starting treatment.

Children

Caution is advised while giving Simvastol 20mg Tablet 25 to children under 18 years of age. Always consult your doctor before giving any medicine to a child

Older Patients

Older patients should take Simvastol 20mg Tablet 25 under medical supervision, as they may be more susceptible to its side effects. Your doctor will guide you based on your health status.

Drug-Drug Interactions

Simvastol 20mg Tablet 25 interacts with the following medicines:

Fibrates: Medicines like fenofibrate or gemfibrozil can increase the risk of muscle problems when taken with Simvastol 20mg Tablet 25.
Antibiotics: Certain antibiotics, such as erythromycin and clarithromycin, may increase simvastatin levels in your blood, raising the risk of side effects.
Antifungal Medicines: Medicines like itraconazole and ketoconazole can significantly increase the concentration of Simvastol 20mg Tablet 25 in your bloodstream.
HIV Protease Inhibitors: Medicines such as ritonavir and nelfinavir can increase simvastatin levels, potentially causing muscle damage.
Calcium Channel Blockers: Verapamil and diltiazem can raise simvastatin levels in your body, increasing the risk of side effects.

Drug-Food Interactions

Simvastol 20mg Tablet 25 may interact with certain foods and beverages.

Grapefruit Juice: Can increase the amount of simvastatin in your blood, potentially raising the risk of side effects.

Drug-Disease Interactions

Simvastol 20mg Tablet 25 interacts with the following diseases:

Liver Disease: Simvastol 20mg Tablet 25 may worsen liver function in patients with existing liver problems.
Kidney Disease: Patients with kidney problems may have an increased risk of muscle-related side effects when taking Simvastol 20mg Tablet 25.
Diabetes: Simvastol 20mg Tablet 25 may slightly increase blood sugar levels in people with diabetes.
Thyroid Disorders: Underactive thyroid may increase the risk of muscle problems when taking Simvastol 20mg Tablet 25.

Daily Dose

The daily dose of Simvastol 20mg Tablet 25 should be taken as prescribed by your doctor. The dosage may change based on your condition's severity and how your body responds to the medicine. Always follow the prescribed dosage without exceeding it unless your doctor advises otherwise.

Over Dose

Taking too much Simvastol 20mg Tablet 25 may cause headaches, nausea, abdominal pain, muscle weakness, or diarrhoea. If you experience severe muscle pain with fever or unusual tiredness after taking extra tablets, inform your doctor promptly.

Missed Dose

If you forget to take a dose, take it as soon as you remember. If it is nearly time for your next dose, skip the missed one and continue your regular schedule. Never take a double dose to make up for the missed one.

Store at room temperature (not exceeding 30°C).
Keep away from light, heat and moisture.
Store in the original packaging to protect from environmental exposure.
Keep out of reach of children.
Do not use after the expiry date printed on the package.

Follow a cholesterol-lowering diet rich in fruits, vegetables, whole grains and lean proteins while limiting foods high in saturated fats and cholesterol (such as fatty meats, full-fat dairy and fried foods).
Engage in regular moderate physical activity (like brisk walking for 30 minutes most days) to help lower your LDL (bad cholesterol) and raise your HDL (good cholesterol).

Fact Box

Available Dosage Types	Tablet
Habit Forming	No
Ailment	High cholesterol, cardiovascular risk, hypercholesterolaemia
Drug Category	HMG-CoA reductase inhibitor
Therapeutic Category	Cholesterol-lowering medicine

Can I take Simvastol 20mg Tablet 25 if I am pregnant or breastfeeding?

No. Simvastol 20mg Tablet 25 is not safe during pregnancy or while breastfeeding. Inform your doctor if you are pregnant or planning to have a baby.

How long do I need to take Simvastol 20mg Tablet 25?

Simvastol 20mg Tablet 25 is usually a long-term medicine for managing cholesterol. Continue taking it as directed, even when you feel well.

What should I do if I miss a dose?

Take it when you remember. If it is nearly time for your next dose, skip the missed one. Never take a double dose.

Can I drink alcohol while taking Simvastol 20mg Tablet 25?

You should avoid alcohol while taking this medicine, as it may increase your risk of liver problems and side effects.

Will Simvastol 20mg Tablet 25 affect my ability to drive?

Most people can drive while taking Simvastol 20mg Tablet 25. However, if you experience dizziness or muscle weakness, avoid driving until these effects pass.

Should I avoid any foods while taking this medicine?

Avoid grapefruit and grapefruit juice while taking Simvastol 20mg Tablet 25, as they can increase the risk of side effects.

What are the most common side effects of Simvastol 20mg Tablet 25?

Common side effects include headache, mild stomach discomfort, constipation, and muscle aches. Most are temporary and improve with continued use.

Last Updated On 15 May. 2025 | 1:22PM (IST)

Certified Content

Written by

Ashmita Borgohain

Medical Content Writer | 12 years

MSc (Applied Genetics)

Reviewed by

Dr. Chhavi Rosha

Medical Content Writer | 9 years

BAMS, FMC, MD Resident

Check out Editorial Policy

Manufacturer details

11/12, Udyog Nagar Industrial Estate, SV Road, Goregaon West, Mumbai, Maharashtra 400104

Country of origin: INDIA

Expiry on or after: December 2025

In case of any issues, contact us:

support@truemeds.in|08069808861

Address: 6th floor, Urmi Corporate Park Solaris, Saki Vihar Road, Andheri East, Mumbai 400071

References

U.S. Food and Drug Administration. (2010). Label: ZOCOR (simvastatin) tablet, film coated. Retrieved 1 April 2025, from https://www.accessdata.fda.gov/drugsatfda_docs/label/2010/019766s078lbl.pdf
MedlinePlus. (n.d.). Simvastatin. U.S. National Library of Medicine. Retrieved 1 April 2025, from https://medlineplus.gov/druginfo/meds/a692030.html
Talreja, O., Kerndt, C. C., & Cassagnol, M. (2023, June 5). Simvastatin. StatPearls - NCBI Bookshelf. https://www.ncbi.nlm.nih.gov/books/NBK532919/
DrugBank. (n.d.). Simvastatin. Retrieved 1 April 2025, from https://go.drugbank.com/drugs/DB00641
Correa, V., Fuchs, F. D., Moreira, L. B., Gerhardt, M., Fuchs, S. C., Sloczinski, C. R., Monteggia, R. G., & Gus, M. (2013). Blood pressure-lowering effect of simvastatin: a placebo-controlled randomized clinical trial with 24-h ambulatory blood pressure monitoring. Journal of Human Hypertension, 28(1), 62–67. https://doi.org/10.1038/jhh.2013.35

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We, at Truemeds make a diligent attempt to deliver accurate, expert- drafted and thoroughly reviewed medicine related information to our consumers. However, it should, by no means, be considered a substitute for prescription from a certified doctor or a trustworthy doctor-patient relationship. In fact we detest any form of self medication without expert advice. The sole purpose of the information on our portal is to educate our consumers, which helps improve the communication between a doctor and a patient. The information by no means is complete in its entirety and should not be used to diagnose or treat any medical condition. No amount of information can replace the experience and expertise of a doctor, therefore his/her advice always holds priority and should be followed appropriately.

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