Pyrolin 0.2mg Injection 1

Pyrolin 0.2mg Injection 1 is used for the following:

• Reduction of salivary, pharyngeal, and tracheobronchial secretions during surgery

• Prevention of intraoperative bradycardia

• Adjunctive treatment for peptic ulcer disease

• Reversal of muscarinic effects during neuromuscular blockade reversal

• Management of excessive drooling (sialorrhea)

• Reduction of gastric acid secretion

• Control of gastrointestinal motility

Pyrolin 0.2mg Injection 1 should be administered as follows:

• This medicine must only be given by a qualified healthcare professional.

• It can be administered through either intramuscular or intravenous routes.

• For intravenous use, it may be given as a direct push or diluted in compatible solutions.

• The injection site should be cleaned with an antiseptic before administration.

• After administration, the injection site may be gently massaged.

• Consult your doctor for specific administration instructions tailored to your condition.

Pyrolin 0.2mg Injection 1 is administered intravenously or intramuscularly.

Pyrolin 0.2mg Injection 1 contains glycopyrrolate (0.2 mg), which works on the body as follows:

• Muscarinic receptor antagonism: Glycopyrrolate blocks muscarinic acetylcholine receptors throughout the body, preventing the neurotransmitter acetylcholine from activating these receptors.

• Decreased secretions: By blocking specific receptors, this medicine reduces secretions from salivary, sweat, and bronchial glands, helping manage excessive secretions during surgical procedures.

• Reduced gastric acid production: Glycopyrrolate decreases stomach acid production, which aids in the management of peptic ulcer disease.

• Limited central nervous system effects: Due to its chemical structure, glycopyrrolate has minimal ability to cross the blood-brain barrier, resulting in fewer effects on the brain compared to other similar medicines.

• Cardiovascular effects: The medicine can prevent bradycardia (an abnormally slow heart rate) that may occur during surgical procedures or in response to certain medications.

• Store Pyrolin 0.2mg Injection 1 at room temperature.

• Keep the injection protected from light and excessive heat in its original container.

• Store away from children's reach.

• Do not use after the expiry date printed on the packaging.

• Protect from freezing.

• If you are receiving Pyrolin 0.2mg Injection 1 for peptic ulcer management, consider eating smaller, more frequent meals rather than three large meals to reduce stomach acid production.

• Avoid strenuous physical activity in hot environments while on this medicine, as it reduces sweating and may increase your risk of overheating (heat prostration).