Oflokem 400 Tablet 10

Alkem Laboratories Ltd.

Strip of 10 Units

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Old MRP ₹198

MRP ~~₹185.63~~

₹92.82

₹9.28/Units

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Prescription required for this medicine

Store Below 30° C

Composition

Ofloxacin (400 Mg)

Strength:

400 MG 200 MG

Oflokem 400 Tablet 10 is primarily used to manage bacterial infections. It is a single-ingredient medicine from the class of antibiotics classified as fluoroquinolones, containing ofloxacin.

This tablet is also used for various conditions, such as urinary tract infections, pneumonia, skin and soft tissue infections, and reproductive organ infections. It's crucial to note that it should not be used for viral infections. Take it in the dose and duration prescribed by your doctor.

Before starting this medicine, inform your doctor about any ongoing medicines or pre-existing conditions you might have. For optimal results, it's important to continue taking this for the duration prescribed by your doctor.

Oflokem 400 Tablet 10 is used for the following.

Uses of Oflokem 400 Tablet 10 are:

Urinary Tract Infections: Manages bacterial infections in the urinary tract.
Respiratory Infections: Controls infections such as pneumonia.
Skin and Soft Tissue Infections: Handles infections caused by bacteria.
Reproductive Organ Infections: Manages bacterial infections in these areas.

Swallow the whole tablet with a glass of water.
Avoid crushing or chewing the tablet.
Keep a consistent schedule for taking this medicine, ideally around 12 hours apart.
Continue to take it for the entire course as prescribed by your doctor, even if symptoms improve earlier.

Oflokem 400 Tablet 10 is taken orally.

Oflokem 400 Tablet 10 may cause some side effects that are usually mild and go away as your body adjusts to the medicine.

A few common side effects of Oflokem 400 Tablet 10:

Digestive: Nausea, vomiting, stomach pain and diarrhoea.
Nervous system: Headache and dizziness.
Sleep: Sleep disturbances.
Genital: Vaginal itching or discharge.

If any side effect does not improve or becomes serious, speak to your doctor. Do not stop taking the medicine unless your doctor advises you to do so.

Management Of Side Effects:

Most side effects are temporary and generally harmless, which resolve on discontinuing the use of Oflokem 400 Tablet 10. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

Here are some general guidelines for managing common side effects:

Nausea: Try taking Oflokem 400 Tablet 10 with food or milk to reduce feelings of nausea.
Stomach pain: Consider taking this medicine after meals to lessen stomach discomfort.

Oflokem 400 Tablet 10 contains ofloxacin (400 mg), which works on the body as follows:

Inhibits Bacterial DNA Enzymes: Ofloxacin works by blocking two enzymes in bacterial DNA, gyrase and topoisomerase IV. These enzymes are vital for the bacteria as they help in DNA replication, transcription, repair, and recombination.
Disrupts Bacterial DNA Processes: By inhibiting these enzymes, ofloxacin disrupts essential DNA processes in bacterial cells, leading to their death. This action helps manage various bacterial infections effectively.

Pregnancy

Caution is advised while taking Oflokem 400 Tablet 10 if you are pregnant. It is best to consult your doctor before taking this medicine.

Breastfeeding

If you are breastfeeding, caution is recommended when taking an Oflokem 400 Tablet 10. Consult your doctor to understand the potential risks and benefits.

Alcohol

While consuming alcohol, caution is advised when taking Oflokem 400 Tablet 10. It's advisable to discuss this with your doctor before starting this medicine.

Liver

If you have liver problems, discuss them with your doctor before starting Oflokem 400 Tablet 10. This medicine may affect liver function.

Kidney

Caution is advised before taking Oflokem 400 Tablet 10 if you have a history of any kidney problems. It is a good idea to consult your doctor before taking this medicine.

Use In Driving And Operating Machinery

Oflokem 400 Tablet 10 may cause dizziness or sleepiness. You should not drive or operate machinery until you know how this medicine affects you.

Allergy

Please inform your doctor if you have any known allergies to ofloxacin or other fluoroquinolone antibiotics before starting Oflokem 400 Tablet 10.

Children

Oflokem 400 Tablet 10 should only be given to children under 18 years of age under medical supervision. Always consult your doctor before giving this medicine to a child.

Older Patients

Older patients should take Oflokem 400 Tablet 10 under medical supervision as they may be more susceptible to its side effects. Caution is advised if patients are above 70 years of age. Your doctor will guide you based on your health status.

Drug-Drug Interactions

Oflokem 400 Tablet 10 interacts with the following medicines:

Supplements: Medicines and dietary supplements containing iron, zinc, or magnesium can interfere with the absorption of Oflokem 400 Tablet 10. Some specific examples include aluminium hydroxide and ferrous sulphate.
Anti-ulcer medicines: Medications like sucralfate can bind to Oflokem 400 Tablet 10 in the stomach, reducing its effectiveness.
Blood thinners: Oflokem 400 Tablet 10 can potentially increase the effect of blood thinners like warfarin, leading to an increased risk of bleeding.

Drug-Food Interactions

Oflokem 400 Tablet 10 does not have any known significant interactions with specific foods.

Drug-Disease Interactions

Oflokem 400 Tablet 10 interacts with the following diseases:

Kidney Disease: If you have kidney disease, your body may process this medicine more slowly, leading to more side effects.
Liver Disease: In patients with liver disease, the metabolism of Oflokem 400 Tablet 10 may be affected, requiring dose adjustments.
Seizures: Oflokem 400 Tablet 10 may increase the risk of seizures or worsen seizures in people who already have this condition.
Myasthenia Gravis: This medicine may worsen muscle weakness in individuals with myasthenia gravis.

Daily Dose

Take the recommended dose of Oflokem 400 Tablet 10 as prescribed by your doctor. The dosage may vary based on your individual health status and how you respond to the medication. It's crucial to adhere to the recommended dosage and not modify it without consulting your doctor.

Over Dose

If you accidentally take more than the prescribed dose of Oflokem 400 Tablet 10, you may experience symptoms such as drowsiness or nausea. In this situation, it is important to inform your doctor and follow their advice.

Missed Dose

If you forget to take a dose of Oflokem 400 Tablet 10, take it as soon as you remember. However, if it's nearly time for your next dose, just skip the missed one and continue with your regular schedule. Do not increase your dosage without speaking with your doctor.

Store an Oflokem 400 Tablet 10 at room temperature, below 30°C.
Protect it from direct light and avoid damp places, maintaining a dry environment.
Always keep out of reach of children.

Increase your water intake for those managing urinary tract infections with Oflokem 400 Tablet 10; this can help flush out bacteria.
If you're taking Oflokem 400 Tablet 10 for respiratory tract infections such as pneumonia, refrain from smoking as it could further irritate your lungs and impede recovery.

Fact Box

Dosage Forms Available	Tablet
Habit Forming	No
Ailment	Urinary Tract Infections, Pneumonia, Skin and Soft Tissue Infections
Drug Category	Antibacterial
Therapeutic Category	Antibiotic

What is Oflokem 400 Tablet 10 used for?

Oflokem 400 Tablet 10 is used to manage a range of bacterial infections, including those of the urinary and respiratory tracts, skin and soft tissues, and reproductive organs.

How does Oflokem 400 Tablet 10 work?

It contains ofloxacin, a fluoroquinolone antibiotic that inhibits essential enzymes in bacteria, disrupting their DNA processes and leading to cell death.

Can I take Oflokem 400 Tablet 10 with food?

Yes, you can take Oflokem 400 Tablet 10 with or without food. However, for best efficacy, it's recommended to take it consistently each day.

What should I do if I miss a dose of Oflokem 400 Tablet 10?

Take the missed dose as soon as you remember unless it's nearly time for the next one. Never double up on doses to compensate.

What are some common side effects of Oflokem 400 Tablet 10?

Common side effects may include nausea, vomiting, stomach pain, diarrhoea, headache, dizziness, sleep disturbances and vaginal itching or discharge. Please consult your doctor if these side effects persist.

Is it safe to use Oflokem 400 Tablet 10 during pregnancy?

Pregnant women should consult their doctor before taking Oflokem 400 Tablet 10 to understand any potential risks or adjustments needed.

How should I store Oflokem 400 Tablet 10?

Store this tablet at room temperature, keeping them away from direct light and moisture.

Last Updated On 18 Sep. 2026 | 7:22AM (IST)

Certified Content

Written by

Dr Vatsalya D Ghanekar

Medical Content Writer | 7 years

MD Ayurveda

Reviewed by

Dr. Meenakshi Maruwada

Medical Content Writer | 10 years

BDS, PGCAD, GMHE (IIM-B)

Check out Editorial Policy

Manufacturer details

Alkem House, Senapati Bapat Marg, Lower Parel, Mumbai Maharashtra- 400013

Country of origin: INDIA

Expiry on or after: January 2027

In case of any issues, contact us:

support@truemeds.in|09240250346

Address: 6th floor, Urmi Corporate Park Solaris, Saki Vihar Road, Andheri East, Mumbai 400071

References

PubChem. (n.d.). Ofloxacin. PubChem. https://pubchem.ncbi.nlm.nih.gov/compound/4583
Ofloxacin: uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB01165
U.S. National Library of Medicine. (2022). Ofloxacin. MedlinePlus. Retrieved 1 April 2024, from https://medlineplus.gov/druginfo/meds/a691005.html
U.S. Food and Drug Administration. (2007). Ofloxacin tablets, USP. FDA. Retrieved 1 April 2024, from https://www.accessdata.fda.gov/drugsatfda_docs/label/2007/019735s058lbl.pdf
Graham, D. B., & Tripp, J. (2023, June 26). Ofloxacin. StatPearls NCBI Bookshelf. https://www.ncbi.nlm.nih.gov/books/NBK549837/

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We, at Truemeds make a diligent attempt to deliver accurate, expert- drafted and thoroughly reviewed medicine related information to our consumers. However, it should, by no means, be considered a substitute for prescription from a certified doctor or a trustworthy doctor-patient relationship. In fact we detest any form of self medication without expert advice. The sole purpose of the information on our portal is to educate our consumers, which helps improve the communication between a doctor and a patient. The information by no means is complete in its entirety and should not be used to diagnose or treat any medical condition. No amount of information can replace the experience and expertise of a doctor, therefore his/her advice always holds priority and should be followed appropriately.

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