Nirmet Injection 100ml is primarily used to manage various bacterial infections such as peritonitis (inflammation of abdominal lining), intra-abdominal abscess (pus in abdomen), and liver abscess. It belongs to a class of medicines known as nitroimidazole antibiotics.
This injection can also be taken for skin and skin structure infections that cause redness, swelling, and pus. Gynecologic infections such as endometritis (inflammation of the uterine lining), tubo-ovarian abscess (swelling and pus in fallopian tubes and ovaries), and postsurgical vaginal cuff infections can also be treated with this injection. Infections of the brain, such as meningitis (inflammation of brain coverings) and brain abscess (pus-filled swelling in the brain), can also be addressed with this injection. Bone and joint infections caused by susceptible bacteria can also be managed with this injection.
Before taking this injection, it is crucial to speak to your doctor for the right dosage and frequency. Be sure to inform your doctor about any pre-existing conditions or ongoing medications you may be taking. If you experience any side effects while on this injection, inform your doctor immediately. For optimal results, continue taking the injection for the duration prescribed by your doctor.
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Nirmet Injection 100ml
Bottle of 100 ML
MRP ₹12.89
₹10.31
₹0.13/ML
100% genuine medicines
Safe & secure payments
15 days Easy returns
Prescription required for this medicine
Store Below 30o C
CompositionAbout Nirmet Injection 100ml
Uses of Nirmet Injection 100ml
Nirmet Injection 100ml is commonly used for managing the following health conditions:
- Intra-abdominal infections like peritonitis, intra-abdominal abscess, and liver abscess, aiding in their resolution
- Infections of the skin, subcutaneous tissue, and soft tissue
- Gynecologic infections like inflammation of the uterus lining, pus in ovaries and fallopian tube and postsurgical vaginal cuff infections
- Infection of the blood
- Bacterial infections affecting bones and joints
- Infections in the brain
- Bacterial infections of the lower respiratory tract
- Inflammation of inner chambers of the heart and valves
Directions for Use of Nirmet Injection 100ml
- This injection will be administered by a healthcare professional.
- Be sure to stay well-hydrated before and after each dose.
- Since this treatment is managed by a healthcare professional, you will receive detailed instructions during administration. Always consult your doctor for personalised guidance.
Route of Administration
Nirmet Injection 100ml is taken intravenously.
Side Effects of Nirmet Injection 100ml
Nirmet Injection 100ml may cause the following side effects:
- Nausea
- Headache
- Dry Mouth
Managing the Side Effects:
Most side effects are temporary and generally harmless, which resolve upon discontinuing the use of Nirmet Injection 100ml. However, if you experience any serious side effects or the symptoms worsen, please inform your doctor.
Here are some guidelines for managing common side effects:
- Dry Mouth: Try sipping water regularly throughout the day to help alleviate this symptom.
How Nirmet Injection 100ml Works?
Nirmet Injection 100ml contains metronidazole (500 mg), which acts on the body as follows:
- It undergoes chemical changes inside the bacterial and protozoa cells that generate some compounds. These compounds interfere with DNA replication and cause damage to the genetic material of the microorganisms. As a result, ornidazole is effective against bacteria and protozoa.
Safety Measures & Warnings
Pregnancy
Nirmet Injection 100ml may cross the placenta in humans. However, there is no reliable information on the risk of birth defects due to this injection. Pregnant women should inform their doctor before taking this injection.
Breastfeeding
Breastfeeding mothers should not take Nirmet Injection 100ml. It may pass to the infant through breast milk. Before taking this injection while breastfeeding, it is recommended to inform your doctor.
Alcohol
Alcohol should be strictly avoided after receiving Nirmet Injection 100ml. It can cause abdominal cramps, nausea, vomiting, headaches, and flushing.
Liver
Patients with mild to moderate liver disease can safely take Nirmet Injection 100ml. No dose adjustment is required in these patients. However, patients with severe liver disease should cautiously take this injection. Dose adjustments are required in such patients. If you have severe liver disease, inform your doctor before taking this injection.
Kidney
Nirmet Injection 100ml should be cautiously administered in patients with severe kidney disease or those undergoing dialysis. Dose adjustments may be required for such patients. However, patients with mild to moderate kidney impairment can safely take this injection. If you have a severe kidney problem, inform your doctor before taking this injection.
Using Machines & Driving
This injection may affect your mental or physical abilities to operate machinery or drive. After receiving this injection, you may experience dizziness and drowsiness. Therefore, avoiding any attentive task is recommended after receiving this injection.
Allergy
Do not take Nirmet Injection 100ml if you are allergic to metronidazole. Read the label and check the ingredients before taking this injection to avoid allergic reactions.
Children
Nirmet Injection 100ml is not intended for children.
Older Patients
Older patients with liver, kidney and heart dysfunction should take this injection cautiously. They may also take other medications that can interact with this injection. Inform your doctor and discuss your prescription medications before taking Nirmet Injection 100ml.
Interactions of Nirmet Injection 100ml
Drug-Drug Interactions
Nirmet Injection 100ml interacts with the following medicines:
- Anticoagulants: Nirmet Injection 100ml increases the effect of medicines like warfarin and heparin, which could raise the risk of bleeding.
- Alcohol-containing medicines: Taking Nirmet Injection 100ml with alcohol-containing medicines like fenoterol, can give rise to unpleasant side effects such as nausea and vomiting.
- Stomach acid reducers: Medicines such as cimetidine may decrease metabolism and reduce blood clearance of this injection which may result in metronidazole toxicity.
- Muscle relaxers: Medicines such as vecuronium may potentiate the effects of vecuronium.
- Immunosuppressants: Medicines such as tacrolimus and cyclosporine. This injection can potentially raise the levels of these medications in the bloodstream.
- Antiarrhythmics: Medicines such as amiodarone and quinidine. This injection can potentially raise the levels of these medications in the bloodstream.
Drug-Disease Interactions
Nirmet Injection 100ml interacts with the following diseases:
- Cockayne syndrome: This injection can lead to hepatotoxicity or acute hepatic failure in patients with Cockayne syndrome.
- Fungal infections: Known or previously unrecognised fungal infections such as candidiasis may present more prominent symptoms during treatment with this injection.
- Blood dyscrasias: This injection can lead to low WBCs.
- Crohn's disease: Patients with Crohn's disease are known to have an increased incidence of gastrointestinal and certain extraintestinal cancers.
Dosage of Nirmet Injection 100ml
Daily Dose
Get your recommended dose of Nirmet Injection 100ml as per your doctor's instructions. Your dosage may be adjusted based on factors like how severe your condition is and how you respond to the medicine. Always stick to the prescribed dosage and don't exceed it without consulting your doctor.
Over Dose
Overdose of injection is unlikely as a healthcare professional administers it.
Missed Dose
In case you miss a dose of Nirmet Injection 100ml, take it as soon as you remember. But if it is almost time for your next dose, skip the missed one and continue with your regular schedule. Please never alter your dosage without consulting your doctor.
Storage
- Store your Nirmet Injection 100ml in its original packaging to protect it from light and moisture.
- Never place the medicine in the freezer or expose it to extreme heat.
- Ensure the product is kept out of reach and sight of children.
Diet & Lifestyle
- If you are taking Nirmet Injection 100ml for bacterial infections in the gut, try to incorporate probiotics like yoghurt into your diet to restore healthy gut bacteria.
- Avoid alcohol while on this medication as it may increase the risk of side effects.
Fact Box
| Available Dosage Types | Infusion
|
| Habit Forming | No |
| Ailment | Bacterial Infections, Amoebic Dysentery |
| Drug Category | Nitroimidazole
|
| Therapeutic Category | Antibiotic |
Frequently Asked Questions (FAQs)
What is Nirmet Injection 100ml used for?
What are the side effects of Nirmet Injection 100ml?
Can I drink alcohol while taking Nirmet Injection 100ml?
Can I use this medicine during pregnancy or breastfeeding?
How should I store my Nirmet Injection 100ml?
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Manufacturer details
Country of origin: INDIA
References
- Container, in P. C. V. (n.d.). Metronidazole Injection, USP. Fda.Gov. (Retrieved August 2023). https://www.accessdata.fda.gov/drugsatfda_docs/label/2017/018657s036lbl.pdf
- Metronidazole 500 mg / 100 ml Intravenous Infusion - Summary of Product Characteristics (SmPC) - (emc). (n.d.). Org.uk. (Retrieved August 2023). https://www.medicines.org.uk/emc/product/1842/smpc
- Metronidazole. (n.d.). Medlineplus.Gov. (Retrieved August 2023). https://medlineplus.gov/druginfo/meds/a689011.html
- Website, N. (2024, April 27). Metronidazole. nhs.uk. https://www.nhs.uk/medicines/metronidazole/
- Metronidazole: Uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB00916
- Aronson, J. K. (Ed.) (2016). Metronidazole. In Meyler's Side Effects of Drugs (16th ed., pp. 989-997). https://www.sciencedirect.com/science/article/pii/B9780444537171010775
Disclaimer
We, at Truemeds make a diligent attempt to deliver accurate, expert- drafted and thoroughly reviewed medicine related information to our consumers. However, it should, by no means, be considered a substitute for prescription from a certified doctor or a trustworthy doctor-patient relationship. In fact we detest any form of self medication without expert advice. The sole purpose of the information on our portal is to educate our consumers, which helps improve the communication between a doctor and a patient. The information by no means is complete in its entirety and should not be used to diagnose or treat any medical condition. No amount of information can replace the experience and expertise of a doctor, therefore his/her advice always holds priority and should be followed appropriately.
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