Melacyl 10 MG Tablet 10

Parry Pharma Pvt Ltd

Pack of 10 Units

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Composition

Methoxsalen (10 Mg)

Melacyl 10 MG Tablet 10 is primarily used for managing vitiligo, a condition that causes white patches on the skin due to loss of pigment-producing cells. It belongs to a class of medications known as photosensitising agents, which work alongside ultraviolet light therapy.characterised by white patches on the skin resulting from the

This medicine can also be used to manage psoriasis, particularly severe cases that haven't responded well to other treatments. In some cases, doctors may prescribe it for cutaneous T-cell lymphoma, a rare type of skin cancer, and occasionally for addressing certain pigmentation issues in patients with albinism.

You should take this medicine exactly as directed by your doctor, who will determine the proper dosage and frequency based on your condition and body weight. Before starting this medicine, inform your doctor about any pre-existing conditions you have or any other medicines you are currently taking.

Melacyl 10 MG Tablet 10 is used for the following:

Treatment of vitiligo patches on the skin
Management of severe psoriasis
Therapy for recalcitrant psoriasis
Photochemotherapy with UVA light exposure
Management of skin pigmentation disorders
Repigmentation of affected skin areas
Stimulation of melanocyte activity in skin
Treatment of certain cases of albinism

Follow these instructions while taking Melacyl 10 MG Tablet 10:

Swallow the tablet whole with a glass of water.
Take this medicine 1.5 to 2 hours before scheduled UV light exposure.
Do not crush, chew, or break the tablet.
Consult your doctor if you miss a scheduled dose.

Melacyl 10 MG Tablet 10 is taken orally.

Melacyl 10 MG Tablet 10 may have the following common side effects:

Nausea
Skin redness
Itching
Sleep disturbances: You might experience difficulty falling asleep or changes in your normal sleep patterns.
Photosensitivity: This means your skin becomes extra sensitive to sunlight, making you more likely to burn even with brief sun exposure.
Dizziness

Managing the Side Effects:

Most side effects are temporary and generally harmless and are resolved by discontinuing the use of Melacyl 10 MG Tablet 10. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

Here are some general guidelines for managing common side effects:

Nausea: Taking Melacyl 10 MG Tablet 10 with food may help reduce feelings of sickness that can occur after ingestion.
Sleep disturbances: Consider taking this medicine earlier in the day rather than in the evening to minimise its effects on your sleep pattern.

Melacyl 10 MG Tablet 10 contains methoxsalen (10 mg), which works on the body as follows:

Photosensitisation: Methoxsalen makes your skin more sensitive to ultraviolet A (UVA) light, which is necessary for the medicine to be effective.
DNA interaction: When activated by UVA light, methoxsalen binds to the DNA in your skin cells, forming cross-links between DNA strands.
Melanocyte stimulation: This process triggers the activity of melanocytes (pigment-producing cells), encouraging them to multiply and migrate to affected areas.
Repigmentation: By stimulating melanocytes, the medicine helps restore normal skin colour to areas affected by vitiligo.
Cell growth regulation: In psoriasis, this medicine helps slow down the rapid skin cell turnover and reduce inflammation, a characteristic symptom of this condition.

Pregnancy

Melacyl 10 MG Tablet 10 is contraindicated during pregnancy. If you are pregnant or planning to conceive, make sure to discuss this with your doctor before starting this medicine. This medicine may cause harmful effects on the developing baby.

Breastfeeding

Melacyl 10 MG Tablet 10 is contraindicated for breastfeeding women. The medicine may pass into breast milk and could affect your baby. Consult your doctor to understand the potential risks and benefits.

Alcohol

Caution is advised while taking Melacyl 10 MG Tablet 10 when consuming alcohol. Alcohol might increase your skin's sensitivity to sunlight, potentially worsening side effects such as skin redness or burning.

Liver

Caution is advised while taking Melacyl 10 MG Tablet 10 if you have mild to moderate liver impairment. It is not recommended for severe liver diseases. Your doctor might need to adjust your dosage based on your liver function tests.

Kidney

Caution is advised before using Melacyl 10 MG Tablet 10 if you have a history of any kidney problems. Your doctor might need to monitor your kidney function during treatment with this medicine.

Using Machines & Driving

Caution is advised while driving or operating machinery after taking Melacyl 10 MG Tablet 10. This medicine may cause dizziness or vision changes in some people, especially during initial treatment.

Allergy

If you have a history of allergies, especially to psoralens or similar medicines, inform your doctor before taking Melacyl 10 MG Tablet 10. Individuals with conditions that cause photosensitivity should avoid this medication.

Children

Caution is advised while giving Melacyl 10 MG Tablet 10 to children under 12 years of age. This medicine is generally not recommended for children unless specifically prescribed by a specialist.

Older Patients

Older patients should take Melacyl 10 MG Tablet 10 under medical supervision, as they may be more susceptible to its side effects. Your doctor may prescribe a lower starting dose and monitor you more closely during treatment.

Drug-Drug Interactions

Melacyl 10 MG Tablet 10 interacts with the following medicines:

Antibiotics: Medicines like doxycycline and ciprofloxacin can dangerously enhance your skin's sensitivity to light when taken with methoxsalen, increasing the risk of severe sunburn.
Diuretics: Furosemide can increase photosensitivity when combined with Melacyl 10 MG Tablet 10, potentially causing severe skin reactions.
Antidiabetic medicines: Medicines such as metformin or gliclazide may have altered effectiveness when used alongside methoxsalen therapy.
Phenothiazines: Medicines such as chlorpromazine or fluphenazine can amplify light sensitivity when taken with Melacyl 10 MG Tablet 10.
Herbal supplements: St. John's Wort can significantly increase photosensitivity when combined with methoxsalen, raising the risk of skin reactions.

Drug-Food Interactions

Melacyl 10 MG Tablet 10 interacts with certain foods containing natural psoralens.

Celery: Contains natural psoralens that can increase your skin's sensitivity to light.
Figs: May enhance photosensitivity when consumed during treatment.
Limes: Can amplify the photosensitising effects of methoxsalen.
Parsley: Contains compounds that may increase the risk of sunburn during treatment.

Drug-Disease Interactions

Melacyl 10 MG Tablet 10 interacts with the following diseases:

Photosensitivity disorders: Conditions like lupus erythematosus or porphyria cutanea tarda can worsen dramatically with methoxsalen therapy.
Skin cancer history: Patients with previous melanoma or squamous cell carcinoma are at an increased risk of cancer recurrence with this medicine.
Eye conditions: Aphakia (absence of eye lens) increases the risk of retinal damage from this photosensitizing medicine.
Cardiac conditions: High blood pressure or heart problems may worsen as methoxsalen can affect blood pressure.

Daily Dose

The daily dose of Melacyl 10 MG Tablet 10 should be taken as prescribed by your doctor. Your dosage may vary based on your body weight, skin type, condition severity, and how you respond to treatment. Never adjust your dose without consulting your doctor.

Over Dose

An overdose of Melacyl 10 MG Tablet 10 may cause severe nausea, dizziness, and extreme skin sensitivity. You might also experience intense redness, blistering, or swelling after light exposure. Contact your doctor if you suspect an overdose has occurred.

Missed Dose

If you forget to take Melacyl 10 MG Tablet 10, take it as soon as you remember, but only if your scheduled UV light therapy hasn't happened yet. Otherwise, skip the missed dose and continue with your regular schedule.

Store Melacyl 10 MG Tablet 10 at room temperature.
Keep it in its original packaging in a dry place away from direct sunlight and moisture.
Avoid storing in bathrooms due to humidity fluctuations.
Always keep out of reach of children and pets.
Do not use after the expiry date printed on the package.

Avoid foods containing natural psoralens (such as celery, parsley, figs and limes) around your treatment times, as these can increase your skin's sensitivity to light.
Wear protective clothing and apply high-SPF sunscreen on non-treated areas when outdoors to protect your skin during the course of your vitiligo or psoriasis management.

Fact Box

Available Dosage Types	Tablet
Habit Forming	No
Ailment	Vitiligo, psoriasis, cutaneous lymphoma
Drug Category	Photosensitising agent
Therapeutic Category	Anti-vitiligo

What is Melacyl 10 MG Tablet 10 used for?

Melacyl 10 MG Tablet 10 is used for managing vitiligo (white patches on skin), psoriasis, and sometimes certain types of skin lymphoma when combined with ultraviolet light therapy.

How does Melacyl 10 MG Tablet 10 work?

It makes your skin more sensitive to ultraviolet A light. When activated by this light, methoxsalen helps stimulate pigment-producing cells in your skin to restore colour.

When should I take Melacyl 10 MG Tablet 10?

You should take it 1.5 to 2 hours before your scheduled ultraviolet light therapy session, with water, as directed by your doctor.

What precautions should I follow during treatment?

Avoid sun exposure for 24 hours after taking the medicine, wear protective clothing, use sunglasses, and attend all follow-up appointments with your doctor.

Can I use Melacyl 10 MG Tablet 10 if I have other skin conditions?

You should not use this medicine if you have conditions that make you sensitive to light, such as lupus or porphyria, or if you have skin cancer.

What side effects might I experience?

You may experience nausea, redness, itching, headaches, dizziness, or sleep disturbances. Severe burning or blistering requires immediate medical attention.

What foods should I avoid while using Melacyl 10 MG Tablet 10?

Avoid foods containing natural psoralens such as celery, parsley, figs and limes around treatment times, as they can increase light sensitivity.

Last Updated On 17 Sep. 2025 | 10:46AM (IST)

Certified Content

Written by

Ashmita Borgohain

Medical Content Writer | 13 years

MSc (Applied Genetics)

Reviewed by

Dr. Chhavi Rosha

Medical Content Writer | 9 years

BAMS, FMC, MD Resident

Check out Editorial Policy

Manufacturer details

402/C, Phase 2, GIDC, Vatva, Ahmedabad, Gujarat 382445

Country of origin: INDIA

Expiry on or after: February 2026

In case of any issues, contact us:

support@truemeds.in|09240250346

Address: 6th floor, Urmi Corporate Park Solaris, Saki Vihar Road, Andheri East, Mumbai 400071

References

Methoxsalen Capsules, USP 10 mg [Soft Gelatin Capsules]. (n.d.). https://dailymed.nlm.nih.gov/dailymed/medguide.cfm?setid=a6ec8292-9189-4ebd-862a-e1725eb29eef
FDA. (2021). UVADEX (Methoxsalen) Sterile Solution, 20 mcg/mL. https://www.accessdata.fda.gov/drugsatfda_docs/label/2018/020969s010lbl.pdf
Methoxsalen G.L. Pharma 20 micrograms/ml solution for blood fraction modification - Summary of Product Characteristics (SmPC) - (emc) | 15562. (n.d.). https://www.medicines.org.uk/emc/product/15562/smpc#gref
NCI Drug Dictionary. (n.d.). Cancer.gov. https://www.cancer.gov/publications/dictionaries/cancer-drug/def/methoxsalen
Methoxsalen: Uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB00553

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We, at Truemeds make a diligent attempt to deliver accurate, expert- drafted and thoroughly reviewed medicine related information to our consumers. However, it should, by no means, be considered a substitute for prescription from a certified doctor or a trustworthy doctor-patient relationship. In fact we detest any form of self medication without expert advice. The sole purpose of the information on our portal is to educate our consumers, which helps improve the communication between a doctor and a patient. The information by no means is complete in its entirety and should not be used to diagnose or treat any medical condition. No amount of information can replace the experience and expertise of a doctor, therefore his/her advice always holds priority and should be followed appropriately.

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