Mclazide M 60 Xr Tablet 15

Mitoch Pharma Pvt Ltd

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Composition

Gliclazide (60 Mg) + Metformin (500 Mg)

Mclazide M 60 Xr Tablet 15 is primarily used to manage type 2 diabetes mellitus in adults. This combination formulation belongs to the class of oral antidiabetic medications.

In addition to its main use, it also helps reduce the risk of complications associated with diabetes, such as heart disease, kidney damage, and nerve problems often linked with uncontrolled blood sugar levels.

Consult your doctor for the correct dosage and frequency based on your health. Before starting this medication, inform your doctor about any pre-existing conditions or other ongoing medications. If you experience any side effects while using this medicine, notify your doctor immediately. To achieve the best results, continue taking the medicine for the full duration prescribed by your doctor.

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Mclazide M 60 Xr Tablet 15 is used for the management of Type 2 diabetes mellitus.

The tablet should be taken whole.
Do not chew, crush, or break the tablet.
Always follow your doctor's instructions regarding dosage and duration.

Mclazide M 60 Xr Tablet 15 is taken orally.

You may experience the following common side effects while taking Mclazide M 60 Xr Tablet 15:

Nausea
Vomiting
Diarrhoea
Abdominal pain
Dizziness
Skin rash
Hypoglycaemia: This is when your blood sugar levels drop below normal.

Managing the Side Effects:

Most side effects are temporary and generally harmless, which resolve on discontinuing the use of Mclazide M 60 Xr Tablet 15. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

Here's how you might manage a couple of common side effects:

Nausea: Try taking Mclazide M 60 Xr Tablet 15 with a meal to help reduce feelings of nausea.
Hypoglycaemia: If you experience hypoglycaemia symptoms after taking this medicine, consider taking it after meals.

Mclazide M 60 Xr Tablet 15 contains two active ingredients:

Metformin (500 mg): As a biguanide, metformin lowers blood glucose levels by decreasing glucose production in the liver, reducing intestinal glucose absorption, and improving insulin sensitivity in peripheral tissues. Essentially, it helps lower your blood sugar by enhancing your body's response to insulin and reducing glucose production in the liver.
Gliclazide (60 mg): As a sulfonylurea, gliclazide stimulates insulin secretion from pancreatic beta cells. It works by interacting with a receptor on the beta cell membrane, initiating a series of events that increase insulin release. In simpler terms, it helps your body produce more insulin.

Pregnancy

Caution is advised while taking Mclazide M 60 Xr Tablet 15 if you are pregnant. It is best to consult your doctor before taking this medicine.

Breastfeeding

If you are breastfeeding, be sure to discuss taking Mclazide M 60 Xr Tablet 15 with your doctor. They can guide you through the potential risks and benefits.

Alcohol

Drinking alcohol might increase the risk of low blood sugar (hypoglycaemia) and lactic acidosis. You should avoid consuming alcohol while taking Mclazide M 60 Xr Tablet 15. Discuss your alcohol consumption with your doctor.

Liver

If you have liver health issues, talk to your doctor before starting Mclazide M 60 Xr Tablet 15. They will assess whether this medicine is suitable for you based on your liver's condition.

Kidney

Mclazide M 60 Xr Tablet 15 should be used with caution if you have a history of kidney problems. Always consult your doctor before taking this medicine in such cases.

Using Machines & Driving

If Mclazide M 60 Xr Tablet 15 makes you feel dizzy or unwell, avoid driving or using heavy machines.

Allergy

If you're allergic to metformin, gliclazide, or any other ingredients in Mclazide M 60 Xr Tablet 15, do not take this medicine. Talk to your doctor about other options available.

Children

Mclazide M 60 Xr Tablet 15 is not recommended for individuals under 18 years of age. Always consult your doctor before administering any medication to a child.

Older Patients

Older patients should take Mclazide M 60 Xr Tablet 15 under medical supervision, as they may be more susceptible to its side effects. Your doctor will guide you based on your health status.

Drug-Drug Interactions

Mclazide M 60 Xr Tablet 15 interacts with the following medicines:

Beta-blockers: Medicines like propranolol and atenolol may enhance the blood sugar-lowering effect of Mclazide M 60 Xr Tablet 15, increasing the risk of hypoglycaemia (low blood sugar).
ACE inhibitors: Medicines such as ramipril or lisinopril can also enhance the glycaemic control of Mclazide M 60 Xr Tablet 15, potentially leading to hypoglycaemia.
Thiazide diuretics: Medications like hydrochlorothiazide may decrease the blood sugar-lowering effect of Mclazide M 60 Xr Tablet 15.
Corticosteroids: Medicines like prednisone and dexamethasone might reduce the hypoglycaemic effect of Mclazide M 60 Xr Tablet 15.
Thyroid hormones: Levothyroxine may lessen the effectiveness of Mclazide M 60 Xr Tablet 15in controlling blood sugar levels.
Cationic medications: Medicines like amiloride, digoxin, and ranitidine can interact with the metformin component of Mclazide M 60 Xr Tablet 15, potentially decreasing its elimination from the body.

Drug-Food Interactions

Certain food items may interact with Mclazide M 60 Xr Tablet 15:

High-fat meals: These can slow down the absorption of Mclazide M 60 Xr Tablet 15, making it less effective in controlling your blood sugar levels.

Drug-Disease Interactions

Mclazide M 60 Xr Tablet 15 interacts with the following diseases:

Renal impairment: As metformin is primarily excreted by the kidneys, those with kidney disease should be cautious when using Mclazide M 60 Xr Tablet 15.
Hepatic impairment: Patients with liver disease should use this medicine with care, as its effectiveness may be affected.
Type 1 diabetes mellitus and diabetic ketoacidosis: Mclazide M 60 Xr Tablet 15 is not recommended for these conditions.

Daily Dose

Your doctor will determine the daily dosage of Mclazide M 60 Xr Tablet 15 based on your individual needs. It's crucial to adhere to this dosage and not exceed it without your doctor's advice.

Over Dose

If you accidentally take more than the prescribed dose of Mclazide M 60 Xr Tablet 15, you may experience symptoms such as nausea, stomach discomfort, or dizziness. If these symptoms persist or worsen, contact your doctor right away.

Missed Dose

In case you forget to take a dose of Mclazide M 60 Xr Tablet 15, take it as soon as you remember. If it's nearly time for your next dose, skip the missed one and continue with your regular schedule. Do not increase your dosage without consulting your doctor.

Store Mclazide M 60 Xr Tablet 15 in a dry place below 30°C.
Protect from direct light and moisture.
Keep out of reach of children.

Incorporate moderate exercise like brisk walking or cycling into your routine. This can help manage blood sugar levels.
Aim to eat a balanced diet with plenty of whole grains, fruits, vegetables, and lean proteins. Limit your intake of sugary foods and drinks, as these can cause spikes in blood sugar levels.

Fact Box

Available Dosage Types	Tablet
Habit Forming	No
Ailment	Type 2 Diabetes Mellitus
Drug Category	Sulfonylurea, Biguanide
Therapeutic Category	Antidiabetic

What is Mclazide M 60 Xr Tablet 15 used for?

It is used to manage type 2 diabetes in adults when diet, exercise, and single-agent therapy fail to control blood sugar levels.

How does Mclazide M 60 Xr Tablet 15 work?

It contains metformin and gliclazide. Metformin reduces blood glucose levels, and gliclazide stimulates insulin secretion from the pancreas.

Can I take this medicine if I have type 1 diabetes?

No, Mclazide M 60 Xr Tablet 15is not suitable for people with type 1 diabetes. It's designed for managing type 2 diabetes.

How should I take my Mclazide M 60 Xr Tablet 15?

You should swallow the tablet whole. Do not crush, chew, or split it.

What might happen if I miss a dose of Mclazide M 60 Xr Tablet 15?

If you miss a dose, take it as soon as you remember. However, if it's nearly time for your next dose, skip the missed one.

Can Mclazide M 60 Xr Tablet 15cause low blood sugar levels?

Yes, one of its ingredients, gliclazide, can cause low blood sugar or hypoglycaemia. Be aware of its symptoms and how to manage it. Consult your doctor for more guidance.

Is it safe to drink alcohol while taking Mclazide M 60 Xr Tablet 15?

No, alcohol can increase the risk of hypoglycaemia and lactic acidosis. Therefore, avoid alcohol consumption while taking this medication.

Last Updated On 13 May. 2025 | 11:20AM (IST)

Certified Content

Written by

Dr. Michelle Frank

Medical Content Writer | 9 years

Doctor of Medicine

Reviewed by

Dr. Betina Chandolia

Lead Medical Content Reviewer | 10 years

BDS, MDS, PGCCL, PGDMH

Check out Editorial Policy

Manufacturer details

Kohinoor Mall, F19, F20, F21, Kirol Rd, opp. Don Bosco Engineering College, Kurla, W, Maharashtra 400070

Country of origin: INDIA

Expiry on or after: October 2025

In case of any issues, contact us:

support@truemeds.in|08069808861

Address: 6th floor, Urmi Corporate Park Solaris, Saki Vihar Road, Andheri East, Mumbai 400071

References

Metformin: MedlinePlus drug information. (n.d.). MedlinePlus - Health Information from the National Library of Medicine. https://medlineplus.gov/druginfo/meds/a696005.html
Campbell DB, Lavielle R, Nathan C. The mode of action and clinical pharmacology of gliclazide: a review. Diabetes Res Clin Pract. 1991;14 Suppl 2:S21-36. https://pubmed.ncbi.nlm.nih.gov/1794262/
About gliclazide. (2022, April 1). NHS. https://www.nhs.uk/medicines/gliclazide/about-gliclazide/
FDA. (n.d.). GLUMETZA™ (metformin hydrochloride extended release tablets) Tablets. https://www.accessdata.fda.gov/drugsatfda_docs/label/2006/021748s002lbl.pdf
Gliclazide. (2024). Diabetes UK. https://www.diabetes.org.uk/guide-to-diabetes/managing-your-diabetes/treating-your-diabetes/tablets-and-medication/sulphonylureas/gliclazide

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Disclaimer

We, at Truemeds make a diligent attempt to deliver accurate, expert- drafted and thoroughly reviewed medicine related information to our consumers. However, it should, by no means, be considered a substitute for prescription from a certified doctor or a trustworthy doctor-patient relationship. In fact we detest any form of self medication without expert advice. The sole purpose of the information on our portal is to educate our consumers, which helps improve the communication between a doctor and a patient. The information by no means is complete in its entirety and should not be used to diagnose or treat any medical condition. No amount of information can replace the experience and expertise of a doctor, therefore his/her advice always holds priority and should be followed appropriately.

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Intellihealth Solutions Private Limited

Office Unit no. 1, 2, 5, & 7, 6th floor Urmi Corporate Park Solaris, Saki Vihar Rd, Opp. L&T Flyover, New Mhada Colony, Budhia Jadhav Wadi, Mumbai, Maharashtra 400072.

CIN: U85320MH2019PTC320566

Telephone:09240250346

Grievance Officer

Name: Chandrasekhar Swaminathan

Email: grievance-officer@truemeds.in

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