Loyzide 3d 0.2/500/80mg Tablet 15

Lloyd Healthcare Pvt.ltd

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MRP ~~₹237.9~~

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Composition

Gliclazide (80 Mg) + Metformin (500 Mg) + Voglibose (0.2 Mg)

Loyzide 3d 0.2/500/80mg Tablet 15 is used to manage Type 2 Diabetes mellitus in adults when blood sugar levels cannot be controlled by diet and exercise alone. It is a combination medicine that belongs to the class of oral anti-diabetic medications.

In addition to helping control blood glucose levels, this medicine works to improve insulin sensitivity in the body and reduce glucose production in the liver. It also helps slow down the absorption of carbohydrates from the intestine, which prevents sharp rises in blood sugar after meals.

Before starting this medicine, inform your doctor about any pre-existing conditions or ongoing medications you may have. If you notice any side effects while taking this medicine, notify your doctor promptly. Continue taking the medicine for the complete duration prescribed by your doctor for optimal results.

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Loyzide 3d 0.2/500/80mg Tablet 15 is used for the following:

Treatment of type 2 diabetes mellitus in adults
Management of uncontrolled blood glucose with diet alone
Control of post-meal blood sugar spikes
Improvement of insulin sensitivity in the body
Reduction of glucose production in the liver
Comprehensive diabetes management in adults
Prevention of diabetes-related complications
Management when single medicines are insufficient

Follow these instructions while taking Loyzide 3d 0.2/500/80mg Tablet 15:

Swallow the tablet whole with a glass of water.
Take this medicine with breakfast or as prescribed by your doctor.
Do not crush, chew, or break the tablet.
Take this medicine at the same time every day.
Continue taking this medicine regularly as advised.
Do not stop taking this medicine without consulting your doctor.
If you have questions about using this medicine, consult your doctor.

Loyzide 3d 0.2/500/80mg Tablet 15 is taken orally.

Loyzide 3d 0.2/500/80mg Tablet 15 may have the following common side effects:

Nausea
Vomiting
Diarrhea
Abdominal pain
Hypoglycaemia: This refers to low blood sugar levels, which can cause shakiness, sweating, dizziness, and confusion.
Vitamin B12 deficiency: Long-term use of this medicine may reduce how well your body absorbs vitamin B12, which is important for nerve function and blood cell formation.

Managing the Side Effects:

Most side effects are temporary and generally harmless and are resolved by discontinuing the use of Loyzide 3d 0.2/500/80mg Tablet 15. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

Here are some general guidelines for managing common side effects:

Nausea: Taking Loyzide 3d 0.2/500/80mg Tablet 15 with food can help reduce feelings of sickness.
Abdominal pain: Try taking this medicine during or immediately after meals to minimise stomach discomfort.

Loyzide 3d 0.2/500/80mg Tablet 15 contains three active ingredients:

Gliclazide (80 mg): This component belongs to the sulfonylurea class and works by stimulating the pancreas to produce more insulin, which helps lower blood glucose (sugar) levels.
Metformin (500 mg): As a biguanide, metformin reduces the amount of glucose your liver produces and improves how your body responds to insulin, making it easier for glucose to enter your cells.
Voglibose (0.2 mg): This alpha-glucosidase inhibitor slows down the digestion of complex carbohydrates in your intestine. This prevents rapid absorption of glucose and helps control post-meal blood sugar spikes.

Pregnancy

Caution is advised while taking Loyzide 3d 0.2/500/80mg Tablet 15 if you are pregnant. It is best to consult your doctor before taking this medicine.

Breastfeeding

Caution is advised while taking Loyzide 3d 0.2/500/80mg Tablet 15 if you are breastfeeding. It is best to consult your doctor before taking this medicine.

Alcohol

Avoid consuming alcohol while taking Loyzide 3d 0.2/500/80mg Tablet 15. Alcohol can increase the risk of low blood sugar (hypoglycaemia) and may affect how well the medicine works. It might also increase the chance of stomach-related side effects.

Liver

Caution is advised while taking Loyzide 3d 0.2/500/80mg Tablet 15 in case of mild to moderate liver impairment. It is not recommended for severe liver diseases. If you have liver problems, discuss them with your doctor before starting Loyzide 3d 0.2/500/80mg Tablet 15. This medicine may affect liver function.

Kidney

Caution is advised before using Loyzide 3d 0.2/500/80mg Tablet 15 if you have a history of any kidney problems. It is a good idea to consult your doctor before taking this medicine.

Using Machines & Driving

Be careful while driving or operating machinery when taking Loyzide 3d 0.2/500/80mg Tablet 15. This medicine may cause low blood sugar (hypoglycaemia), which can make you feel dizzy and tired or affect your concentration. Monitor your blood sugar levels regularly.

Allergy

If you have a known allergy to gliclazide, metformin, voglibose, or any other ingredients in Loyzide 3d 0.2/500/80mg Tablet 15, do not take this medicine. Tell your doctor about any previous allergic reactions you have experienced with any medicines.

Children

Loyzide 3d 0.2/500/80mg Tablet 15 is not recommended for children under 18 years of age. This medicine is designed specifically for managing type 2 diabetes in adults. Consult your doctor before giving any medicine to your child.

Older Patients

Older patients should take Loyzide 3d 0.2/500/80mg Tablet 15 under medical supervision, as they may be more susceptible to its side effects. Caution is advised if you are above 65 years of age. Older patients might also have liver and kidney issues and might be on other medications. Your doctor will guide you based on your health status.

Drug-Drug Interactions

Loyzide 3d 0.2/500/80mg Tablet 15 interacts with the following medicines:

Insulin or anti-diabetic medicines: When taken with insulin, glimepiride or pioglitazone, Loyzide 3d 0.2/500/80mg Tablet 15 may increase the risk of hypoglycaemia (low blood sugar).
Corticosteroids: Medicines like prednisolone and dexamethasone can reduce the blood sugar-lowering effect of Loyzide 3d 0.2/500/80mg Tablet 15.
Diuretics: Water tablets like furosemide and hydrochlorothiazide may affect kidney function, increasing the risk of lactic acidosis when taken with Loyzide 3d 0.2/500/80mg Tablet 15.
Thyroid medicines: Levothyroxine and liothyronine may alter blood glucose levels when used alongside Loyzide 3d 0.2/500/80mg Tablet 15.
Antibiotics: Certain antibiotics like ciprofloxacin and clarithromycin may interfere with the metabolism of gliclazide in Loyzide 3d 0.2/500/80mg Tablet 15.

Drug-Food Interactions

Loyzide 3d 0.2/500/80mg Tablet 15 may interact with certain foods that affect blood sugar levels.

Grapefruit juice: May increase the concentration of gliclazide in your bloodstream.
High-carbohydrate foods: May reduce the effectiveness of voglibose in controlling post-meal glucose spikes.

Drug-Disease Interactions

Loyzide 3d 0.2/500/80mg Tablet 15 interacts with the following diseases:

Kidney disease: Patients with impaired kidney function may experience increased metformin levels, raising the risk of lactic acidosis.
Liver problems: Reduced liver function can affect the metabolism of gliclazide, potentially causing hypoglycaemia.
Vitamin B12 deficiency: Long-term use of Loyzide 3d 0.2/500/80mg Tablet 15 may worsen B12 deficiency due to the metformin component.
Diabetic ketoacidosis: Loyzide 3d 0.2/500/80mg Tablet 15 is not suitable for treating this acute complication of diabetes.

Daily Dose

The daily dose of Loyzide 3d 0.2/500/80mg Tablet 15 should be taken as prescribed by your doctor. Your dosage may change based on your blood sugar levels and individual response to treatment. Always follow the prescribed dosage and never exceed it without consulting your doctor.

Over Dose

Taking too much Loyzide 3d 0.2/500/80mg Tablet 15 may cause low blood sugar (hypoglycaemia). You might also feel shaky, sweaty, dizzy, or confused. If you experience these symptoms, consume some sugar, fruit juice, or glucose tablets immediately.

Missed Dose

If you forget to take Loyzide 3d 0.2/500/80mg Tablet 15, take it as soon as you remember. If it's almost time for your next dose, skip the missed one and continue your regular schedule. Never take a double dose to make up for a missed one.

Store Loyzide 3d 0.2/500/80mg Tablet 15 at a temperature not exceeding 25°C.
Keep away from direct sunlight and moisture.
Store in the original packaging to protect the tablet from environmental exposure.
Keep out of reach of children.

Follow a low-carbohydrate diet with plenty of fibre-rich foods like vegetables and whole grains to help maintain stable blood glucose (sugar) levels throughout the day.
Engage in at least 30 minutes of moderate physical activity (like brisk walking) most days of the week, as regular exercise improves insulin sensitivity and helps control your blood sugar.

Fact Box

Available Dosage Types	Tablet
Habit Forming	No
Ailment	Type 2 diabetes, hyperglycaemia
Drug Category	Triple anti-diabetic combination
Therapeutic Category	Anti-diabetic medicine

How does Loyzide 3d 0.2/500/80mg Tablet 15 work?

Loyzide 3d 0.2/500/80mg Tablet 15 works through three medicines that lower blood sugar in different ways. Gliclazide helps your pancreas release more insulin, metformin reduces sugar production in your liver, and voglibose slows carbohydrate digestion.

When should I take Loyzide 3d 0.2/500/80mg Tablet 15?

You should take Loyzide 3d 0.2/500/80mg Tablet 15 as prescribed by your doctor. Regular timing helps maintain steady medicine levels in your body.

What side effects might I experience with Loyzide 3d 0.2/500/80mg Tablet 15?

Common side effects include stomach discomfort, nausea, diarrhoea, and low blood sugar (hypoglycaemia). Most digestive issues improve with time. Carry glucose tablets in case of low blood sugar symptoms.

Can I take Loyzide 3d 0.2/500/80mg Tablet 15 with other medicines?

Loyzide 3d 0.2/500/80mg Tablet 15 may interact with several medicines including pain relievers, water pills (diuretics), steroids, and some antibiotics. Always inform your doctor about all medicines you currently take.

What should I do if I miss a dose?

If you miss a dose, take it as soon as you remember. However, if it's almost time for your next dose, skip the missed dose and continue with your regular schedule. Never take a double dose.

What lifestyle changes should I follow while taking Loyzide 3d 0.2/500/80mg Tablet 15?

Follow a balanced diet, exercise regularly, monitor your blood sugar levels, limit alcohol consumption, and attend regular check-ups. These habits improve how well Loyzide 3d 0.2/500/80mg Tablet 15 works for managing diabetes.

How should I store Loyzide 3d 0.2/500/80mg Tablet 15?

Store Loyzide 3d 0.2/500/80mg Tablet 15 at a temperature of no more than 25°C in a dry place away from direct sunlight and moisture. Keep it out of children's reach and don't use it after the expiry date.

Last Updated On 16 May. 2025 | 7:00AM (IST)

Certified Content

Written by

Ashmita Borgohain

Medical Content Writer | 12 years

MSc (Applied Genetics)

Reviewed by

Dr. Osama Ahmed

Medical Content Writer | 3 years

Bachelor of Dental Surgery

Check out Editorial Policy

Manufacturer details

702, Balaji Buisness Park, Andheri Kurla Road, Marol Naka, Andheri East, Mumbai, Maharashtra 400059

Country of origin: INDIA

Expiry on or after: October 2025

In case of any issues, contact us:

support@truemeds.in|08069808861

Address: 6th floor, Urmi Corporate Park Solaris, Saki Vihar Road, Andheri East, Mumbai 400071

References

Gliclazide: Uses, Interactions, Mechanism of Action - DrugBank https://go.drugbank.com/drugs/DB01120
Metformin: Uses, Interactions, Mechanism of Action https://go.drugbank.com/drugs/DB00331
MedlinePlus. (n.d.). Metformin. In MedlinePlus. Retrieved 1 April 2025, from https://medlineplus.gov/druginfo/meds/a696005.html
Voglibose: Uses, Interactions, Mechanism of Action - DrugBank https://go.drugbank.com/drugs/DB04878

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Disclaimer

We, at Truemeds make a diligent attempt to deliver accurate, expert- drafted and thoroughly reviewed medicine related information to our consumers. However, it should, by no means, be considered a substitute for prescription from a certified doctor or a trustworthy doctor-patient relationship. In fact we detest any form of self medication without expert advice. The sole purpose of the information on our portal is to educate our consumers, which helps improve the communication between a doctor and a patient. The information by no means is complete in its entirety and should not be used to diagnose or treat any medical condition. No amount of information can replace the experience and expertise of a doctor, therefore his/her advice always holds priority and should be followed appropriately.

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Intellihealth Solutions Private Limited

Office Unit no. 1, 2, 5, & 7, 6th floor Urmi Corporate Park Solaris, Saki Vihar Rd, Opp. L&T Flyover, New Mhada Colony, Budhia Jadhav Wadi, Mumbai, Maharashtra 400072.

CIN: U85320MH2019PTC320566

Telephone:09240250346

Grievance Officer

Name: Chandrasekhar Swaminathan

Email: grievance-officer@truemeds.in

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