Denac 100 Mg Tablet Sr 10

Franklin Laboratories (India) Pvt. Ltd.

Strip of 10 Units

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Composition

Diclofenac (100 Mg)

Denac 100 Mg Tablet Sr 10 is used to relieve pain, swelling and stiffness in conditions such as rheumatoid arthritis and osteoarthritis, and in acute muscle and joint injuries. Its sustained-release form gives longer-lasting pain control.

It contains diclofenac, an anti-inflammatory painkiller (NSAID). It works by blocking the chemicals that cause pain and inflammation.

Take the tablet whole exactly as prescribed, preferably with food.

Tell your doctor about any stomach, kidney or heart conditions before use, and report black or tarry stools or persistent stomach pain.

Denac 100 Mg Tablet Sr 10 is used to relieve pain and inflammation.

Uses of Denac 100 Mg Tablet Sr 10 are:

Arthritis: Relieves pain, swelling and stiffness in osteoarthritis and rheumatoid arthritis.
Injuries: Eases pain from muscle and joint injuries.
Long-Lasting Relief: Provides prolonged pain control through its sustained-release form.

Here's how you should take Denac 100 Mg Tablet Sr 10:

Swallow the tablet whole with a glass of water.
Avoid crushing or breaking the tablet.
Do not exceed the recommended dose without consulting your doctor.
Remember not to stop taking this medicine without consulting your doctor first.

Denac 100 Mg Tablet Sr 10 is taken orally.

Denac 100 Mg Tablet Sr 10 may cause some common side effects, which mostly affect the digestive tract if used for a prolonged duration.

A few Common Side Effects of Denac 100 Mg Tablet Sr 10 :

Digestive: Nausea, vomiting, stomach pain, heartburn, indigestion, flatulence, or altered bowel movements.
Neurological: Headache, minor dizziness, or transient drowsiness.
Skin: Mild skin rashes, itching, or localised hives in sensitive individuals.

If side effects persist, look serious, or if you notice dark stools or severe abdominal burning, stop taking it and consult your physician right away.

Management Of Side Effects:

Most side effects are temporary and generally harmless, which resolve on discontinuing the use of Denac 100 Mg Tablet Sr 10. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

You can try taking Denac 100 Mg Tablet Sr 10 with food to lessen effects like diarrhoea, stomach pain, and nausea.

Denac 100 Mg Tablet Sr 10 contains diclofenac (100 mg), which acts in the body in the following ways:

Prostaglandin Inhibition: Diclofenac works by blocking the production of certain chemicals called prostaglandins that are responsible for causing pain, inflammation, and fever.
Enzyme Blocking: The medication inhibits cyclooxygenase enzymes (COX-1 and COX-2) which play a vital role in synthesizing prostaglandins. This inhibition leads to decreased pain and inflammation.
Sustained Release: The extended-release formulation of Denac 100 Mg Tablet Sr 10 ensures a steady release of diclofenac over an extended period. This maintains consistent levels of the medicine in the body for prolonged relief.

Pregnancy

Denac 100 Mg Tablet Sr 10 is contraindicated during pregnancy. If you are pregnant or planning to conceive, it's crucial to discuss with your doctor before starting this medicine.

Breastfeeding

Denac 100 Mg Tablet Sr 10 should be avoided if you are breastfeeding. Please consult your doctor to understand the potential risks and benefits.

Alcohol

It's advisable to avoid alcohol consumption while taking Denac 100 Mg Tablet Sr 10 as it may enhance the risk of stomach irritation, ulcers, and bleeding.

Liver

Caution is advised while taking Denac 100 Mg Tablet Sr 10 if you have any liver health issues, especially mild to moderate liver impairment. This medicine is not recommended for severe liver diseases as it could affect liver function.

Kidney

If you have any kidney problems, it's recommended you take caution before using Denac 100 Mg Tablet Sr 10. Please consult your doctor to discuss any potential risks or complications.

Use In Driving And Operating Machinery

As Denac 100 Mg Tablet Sr 10 can cause side effects like dizziness or headache, it might affect your ability to drive or operate machinery. It's best to know how this medicine affects you before attempting such tasks.

Allergy

Denac 100 Mg Tablet Sr 10 is contraindicated if you have known hypersensitivity to diclofenac or other NSAIDs. If you've had allergies to similar medicines in the past, discuss this with your doctor.

Children

Caution is advised while giving Denac 100 Mg Tablet Sr 10 to children under 18 years of age. Always consult your doctor before giving this medicine to a child.

Older Patients

Older patients should take Denac 100 Mg Tablet Sr 10 under medical supervision as they may be more susceptible to its side effects, especially if they have liver and kidney issues or are taking other medication. Your doctor will guide you based on your health status.

Drug-Drug Interactions

Denac 100 Mg Tablet Sr 10 interacts with the following medicines:

Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) and salicylates: Increased use of medicines like ibuprofen and aspirin can increase the risk of stomach bleeding when taken with Denac 100 Mg Tablet Sr 10.
Anticoagulants and antiplatelet agents: Medicines such as warfarin and clopidogrel may cause increased bleeding when taken together with Denac 100 Mg Tablet Sr 10.
Diuretics and antihypertensive drugs: There is a potential risk of decreased blood pressure control when medicines like furosemide and ACE inhibitors are used with Denac 100 Mg Tablet Sr 10.
Lithium and digoxin: Denac 100 Mg Tablet Sr 10 may increase the levels of lithium and digoxin in the body, leading to increased side effects.

Drug-Food Interactions

There are no specific food interactions known for Denac 100 Mg Tablet Sr 10.

Drug-Disease Interactions

Denac 100 Mg Tablet Sr 10 interacts with the following diseases:

Stomach ulcers: This medicine should be used cautiously in people with a history of stomach ulcers due to the increased risk of worsening of their condition.
Liver or kidney disease: People with liver or kidney disease should be cautious as Denac 100 Mg Tablet Sr 10 could exacerbate their condition.
Heart problems: Patients with heart problems might experience worsened conditions while using this medicine.
High blood pressure and asthma: The use of Denac 100 Mg Tablet Sr 10 may lead to increased blood pressure and may trigger an asthma attack.
Bleeding Disorders: If you have a bleeding disorder, the use of Denac 100 Mg Tablet Sr 10 could increase the risk of bleeding.

Daily Dose

The daily dose of Denac 100 Mg Tablet Sr 10 should be taken as directed by your doctor. This dosage may vary depending on factors such as the severity of your condition and your response to the medication. Always adhere to the prescribed dosage and avoid exceeding it without consulting your doctor.

Over Dose

If you accidentally take more Denac 100 Mg Tablet Sr 10 than prescribed, you may experience common symptoms like lethargy, nausea, stomach pain, or slight dizziness. If these symptoms persist or worsen, inform your doctor.

Missed Dose

If you forget to take your Denac 100 Mg Tablet Sr 10 at the usual time, take it as soon as you remember. However, if it's almost time for your next dose, skip the one you missed and go back to your regular schedule. Don't double-up doses without consulting your doctor.

Keep Denac 100 Mg Tablet Sr 10 in a cool, dry place where the temperature stays below 30°C.
Protect it from light and do not expose it to moisture.
Make sure to keep this medicine out of reach of children.
Always check the expiry date on the package before taking Denac 100 Mg Tablet Sr 10.

Since Denac 100 Mg Tablet Sr 10 is used to manage pain and inflammation related to arthritis, try to maintain a balanced diet rich in omega-3 fatty acids. Foods like fish, flaxseeds, and walnuts can help reduce inflammation.
Regular low-impact exercises such as swimming or walking can help relieve stiffness and improve joint mobility, which can be beneficial in managing arthritic conditions. However, avoid strenuous activities that may exacerbate your joint pain or inflammation.

Fact Box

Dosage Forms Available	Tablet ER
Habit Forming	No
Ailment	Rheumatoid arthritis, Osteoarthritis, Musculoskeletal injuries
Drug Category	NSAID/Prostaglandin Synthesis Inhibitor
Therapeutic Category	Nonsteroidal Anti-inflammatory

Is Denac 100 Mg Tablet Sr 10 a narcotic substance?

No, Denac 100 Mg Tablet Sr 10 isn't a narcotic. It's a nonsteroidal anti-inflammatory drug (NSAID), used to manage pain and inflammation without any potential for abuse or dependence.

Can Denac 100 Mg Tablet Sr 10 cause damage to my kidneys?

Long-term use of high doses of Denac 100 Mg Tablet Sr 10 may lead to kidney problems. Always consult your doctor before using this medicine.

Is it safe to take Denac 100 Mg Tablet Sr 10 during pregnancy?

You should avoid taking Denac 100 Mg Tablet Sr 10 during pregnancy, especially in the third trimester, as it can harm the baby. Always consult your doctor before using this medicine.

Can I consume alcohol while I am on Denac 100 Mg Tablet Sr 10?

It is advisable to avoid alcohol when taking Denac 100 Mg Tablet Sr 10 because it can increase the risk of stomach irritation, ulcers and bleeding. Discuss your alcohol intake with your doctor.

How quickly does Denac 100 Mg Tablet Sr 10 start working?

The time for pain relief varies from person to person and depends on the condition being managed. Some may feel relief within hours; others might need consistent use over days.

Can I crush or chew Denac 100 Mg Tablet Sr 10?

No, you should swallow the tablet whole with water and not crush, chew or break it. This is because it's an extended-release formulation that needs to release medicine slowly.

What precautions should I take while using Denac 100 Mg Tablet Sr 10?

Use caution if you have stomach ulcers, bleeding disorders, liver or kidney disease, heart problems, high blood pressure, or asthma.

Last Updated On 26 Aug. 2026 | 2:26PM (IST)

Certified Content

Written by

Ashmita Borgohain

Medical Content Writer | 14 years

MSc (Applied Genetics)

Reviewed by

Dr. Alina Panjwani

Medical Content Writer | 8 years

BDS

Check out Editorial Policy

Manufacturer details

386/1, Maharani Jhansi Road, Civil Lines, Ludhiana, Punjab 141001

Country of origin: INDIA

Expiry on or after: January 2027

In case of any issues, contact us:

support@truemeds.in|09240250346

Address: 6th floor, Urmi Corporate Park Solaris, Saki Vihar Road, Andheri East, Mumbai 400071

References

DailyMed. (n.d.). Diclofenac sodium tablet, extended-release [Web content]. https://dailymed.nlm.nih.gov/dailymed/fda/fdaDrugXsl.cfm?setid=ecaa39b8-067c-80d7-e053-2a95a90a7354&type=display
U.S. Food & Drug Administration. (n.d.). Diclofenac sodium extended-release tablets [PDF file]. https://www.accessdata.fda.gov/drugsatfda_docs/psg/Diclofenac_Sodium_ERtab_20254_RC10-09.pdf
DailyMed. (n.d.). Diclofenac sodium tablet, extended-release [Web content]. https://dailymed.nlm.nih.gov/dailymed/fda/fdaDrugXsl.cfm?setid=d349b4ca-3aec-44a8-a4d5-87be4c822190
National Health Service. (n.d.). Diclofenac [Web content]. https://www.nhs.uk/medicines/diclofenac/

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Disclaimer

We, at Truemeds make a diligent attempt to deliver accurate, expert- drafted and thoroughly reviewed medicine related information to our consumers. However, it should, by no means, be considered a substitute for prescription from a certified doctor or a trustworthy doctor-patient relationship. In fact we detest any form of self medication without expert advice. The sole purpose of the information on our portal is to educate our consumers, which helps improve the communication between a doctor and a patient. The information by no means is complete in its entirety and should not be used to diagnose or treat any medical condition. No amount of information can replace the experience and expertise of a doctor, therefore his/her advice always holds priority and should be followed appropriately.

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CIN: U62099MH2019PTC320566

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