Ampril 5/5 MG Tablet 10

Biogenetic Pharmaceuticals

Pack of 10 Units

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MRP ~~₹35~~

₹28

₹3.5/Units

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Composition

Amlodipine (5 Mg) + Enalapril (5 Mg)

Ampril 5/5 MG Tablet 10 is used for managing high blood pressure (hypertension) in adults when a single medicine isn't enough to control it. It is a combination medicine that belongs to the class of antihypertensive medications.

In addition to its primary use, this medicine may also help manage angina pectoris (chest pain due to reduced blood flow to the heart). It can also reduce the risk of hospitalisation in patients with congestive heart failure, a condition in which the heart cannot pump blood effectively.

This medicine should be taken orally as directed by your doctor. Before starting this medication, inform your doctor about any pre-existing medical conditions or any other medicines you are currently taking. If you notice any side effects while using this medicine, consult your doctor immediately. Continue taking the medicine for the full duration prescribed by your doctor for optimal results.

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Ampril 5/5 MG Tablet 10 is used for the following:

Treatment of high blood pressure
Management of uncontrolled hypertension
Reduction of peripheral vascular resistance
Prevention of cardiovascular complications
Management of angina pectoris
Lowering the risk of hospitalisation in heart failure patients
Blood pressure control in kidney disease
Maintenance of blood vessel health
Combination therapy for resistant hypertension

Follow these instructions while taking Ampril 5/5 MG Tablet 10:

Swallow the tablet whole with a full glass of water.
Do not crush, break or chew the tablet.
Avoid standing up too quickly after sitting or lying down.
Continue taking this medicine even if you feel well.
Consult your doctor before stopping this medicine.

Ampril 5/5 MG Tablet 10 is taken orally.

Ampril 5/5 MG Tablet 10 may have the following common side effects:

Headache
Dizziness
Fatigue
Nausea
Ankle swelling
Cough
Hypotension: This means abnormally low blood pressure, which may cause you to feel lightheaded or faint, especially when standing up quickly.

Managing the Side Effects:

Most side effects are temporary and generally harmless, which resolve on discontinuing the use of Ampril 5/5 MG Tablet 10. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

Here are some general guidelines for managing common side effects:

Dizziness: Try taking Ampril 5/5 MG Tablet 10 at bedtime to reduce the impact of dizziness during your daily activities.
Nausea: Taking this medicine with food may help reduce feelings of nausea.

Ampril 5/5 MG Tablet 10 contains two active ingredients:

Amlodipine (5 mg): A calcium channel blocker that prevents calcium from entering the muscle cells of your heart and blood vessels. This action helps blood vessels to relax and widen, lowering blood pressure and improving blood flow.
Enalapril (5 mg): An angiotensin-converting enzyme (ACE) inhibitor that blocks the formation of angiotensin II, a substance that narrows blood vessels. By reducing this substance, enalapril causes blood vessels to relax and widen, decreasing blood pressure.

Pregnancy

If you are pregnant or planning to conceive, make sure to discuss this with your doctor before starting Ampril 5/5 MG Tablet 10. ACE inhibitors like enalapril can harm the developing foetus, especially during the second and third trimesters.

Breastfeeding

Caution is advised while taking Ampril 5/5 MG Tablet 10 if you are breastfeeding. Both active ingredients in this medicine may pass into breast milk. It is best to consult your doctor before taking this medicine.

Alcohol

Alcohol may increase the blood pressure-lowering effect of Ampril 5/5 MG Tablet 10, potentially causing an excessive drop in blood pressure. This can lead to dizziness, light-headedness, or fainting. It's advisable to avoid alcohol while taking this medicine.

Liver

Both amlodipine and enalapril are processed by the liver, and liver problems may affect how your body handles Ampril 5/5 MG Tablet 10. If you have liver problems, discuss them with your doctor before starting this medicine.

Kidney

Ampril 5/5 MG Tablet 10 is not recommended in patients with bilateral renovascular disease (narrowing of arteries that supply the kidneys). Your doctor may need to adjust your dosage based on your kidney function.

Using Machines & Driving

Ampril 5/5 MG Tablet 10 may cause dizziness, especially when you first start taking it or when the dose is increased. Avoid driving, operating machinery, or performing activities requiring alertness until you know how this medicine affects you.

Allergy

If you have a history of allergic reactions to amlodipine, enalapril, or any other ACE inhibitors or calcium channel blockers, do not take Ampril 5/5 MG Tablet 10.

Children

Caution is advised while giving Ampril 5/5 MG Tablet 10 to children under 18 years of age. The safety and efficacy of this medicine have not been established in children. Always consult your doctor before giving this medicine to a child.

Older Patients

Older patients should take Ampril 5/5 MG Tablet 10 under medical supervision, as they may be more sensitive to its blood pressure-lowering effects. Caution is advised if you are above 65 years of age. Always talk with your doctor before starting this medicine.

Drug-Drug Interactions

Ampril 5/5 MG Tablet 10 interacts with the following medicines:

Diuretics: Medicines like furosemide and hydrochlorothiazide may increase the risk of hypotension (low blood pressure) when taken with Ampril 5/5 MG Tablet 10.
Potassium supplements: Medicines such as potassium chloride and potassium-sparing diuretics like spironolactone may increase the risk of hyperkalaemia (high potassium levels).
NSAIDs: Medicines like ibuprofen and naproxen may reduce the blood pressure-lowering effect of Ampril 5/5 MG Tablet 10.

Drug-Food Interactions

Ampril 5/5 MG Tablet 10 may interact with certain foods:

Grapefruit or grapefruit juice: Avoid grapefruit or grapefruit juice, as it can increase amlodipine levels and cause low blood pressure or dizziness.
Potassium-rich foods: Avoid potassium-rich foods (like bananas, oranges) and salt substitutes, as enalapril can raise potassium levels, increasing the risk of hyperkalemia.

Drug-Disease Interactions

Ampril 5/5 MG Tablet 10 interacts with the following diseases:

Heart disease: Patients with heart valve problems or recent heart attacks should use this medicine with caution.
Diabetes: Ampril 5/5 MG Tablet 10 may affect blood glucose control in diabetic patients.
Bilateral renovascular disease: This medicine is contraindicated, as it can worsen kidney function in this condition.

Daily Dose

The daily dose of Ampril 5/5 MG Tablet 10 should be taken as prescribed by your doctor. The dosage may change based on individual factors such as the severity of your hypertension and response to treatment. Always follow the prescribed dosage.

Over Dose

Taking too much Ampril 5/5 MG Tablet 10 may cause dizziness, weakness, fatigue, nausea, and swelling in the ankles. You might also experience low blood pressure, a headache, and feeling faint when standing up quickly.

Missed Dose

If you forget to take Ampril 5/5 MG Tablet 10, take it as soon as you remember. If it's almost time for your next dose, skip the missed one and resume your regular schedule. Never increase your dosage without consulting your doctor.

Store Ampril 5/5 MG Tablet 10 at room temperature.
Keep the medicine in its original packaging until you need to take it.
Protect from light and moisture.
Store it in a place where children cannot reach it.
Do not use after the expiry date printed on the package.

Reduce your salt intake, as high sodium consumption can raise blood pressure. Try flavouring foods with herbs and spices instead of salt.
Regular physical activity like brisk walking for 30 minutes most days of the week can help manage hypertension (high blood pressure) and improve the effectiveness of your blood pressure medicine.

Fact Box

Available Dosage Types	Tablet
Habit Forming	No
Ailment	Hypertension, Angina pectoris, Heart failure
Drug Category	Calcium channel blocker, ACE inhibitor
Therapeutic Category	Antihypertensive

Can I take Ampril 5/5 MG Tablet 10 if I am pregnant or breastfeeding?

No, this medicine isn't recommended during pregnancy or breastfeeding, as it may harm your baby. Consult your doctor about safer alternatives.

What should I do if I miss a dose?

Take it when you remember unless it's nearly time for your next dose. In that case, skip the missed dose. Never take double doses.

Can I stop taking Ampril 5/5 MG Tablet 10 when my blood pressure normalises?

Never stop taking this medicine without your doctor's advice, even if your blood pressure readings improve. Sudden stopping can cause dangerous pressure spikes.

Are there any foods I should avoid with this medicine?

Avoid Grapefruit, limit salty/potassium rich foods and alcohol, as they can work against the blood pressure-lowering effects of Ampril 5/5 MG Tablet 10.

How long before this medicine starts working?

You may notice some effect within days, but the full blood pressure-lowering benefit (antihypertensive effect) typically takes several weeks to develop.

Can I drive after taking Ampril 5/5 MG Tablet 10?

Be cautious when driving initially, as this medicine may cause dizziness. Wait to see how it affects you before driving or operating machinery.

What side effects should I watch for?

Common side effects include headache, dizziness, swollen ankles (oedema), tiredness, and a dry cough. Contact your doctor if these become troublesome.

Last Updated On 27 May. 2025 | 2:49PM (IST)

Certified Content

Written by

Ashmita Borgohain

Medical Content Writer | 12 years

MSc (Applied Genetics)

Reviewed by

Dr. Chhavi Rosha

Medical Content Writer | 9 years

BAMS, FMC, MD Resident

Check out Editorial Policy

Manufacturer details

Vill Manpura, Nlg., Nalagarh, Solan - 174101

Expiry on or after: October 2025

In case of any issues, contact us:

support@truemeds.in|08069808861

Address: 6th floor, Urmi Corporate Park Solaris, Saki Vihar Road, Andheri East, Mumbai 400071

References

Faruqi, A., Patel, P., & Jain, A. (2024, February 13). Enalapril. StatPearls - NCBI Bookshelf. https://www.ncbi.nlm.nih.gov/books/NBK557708/
Enalapril: Uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB00584
Amlodipine: Uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB00381
DailyMed - AMLODIPINE- amlodipine besylate tablet. (n.d.). https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=b52e2905-f906-4c46-bb24-2c7754c5d75b
Amlodipine: MedlinePlus drug information. (n.d.). https://medlineplus.gov/druginfo/meds/a692044.html

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We, at Truemeds make a diligent attempt to deliver accurate, expert- drafted and thoroughly reviewed medicine related information to our consumers. However, it should, by no means, be considered a substitute for prescription from a certified doctor or a trustworthy doctor-patient relationship. In fact we detest any form of self medication without expert advice. The sole purpose of the information on our portal is to educate our consumers, which helps improve the communication between a doctor and a patient. The information by no means is complete in its entirety and should not be used to diagnose or treat any medical condition. No amount of information can replace the experience and expertise of a doctor, therefore his/her advice always holds priority and should be followed appropriately.

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Office Unit no. 1, 2, 5, & 7, 6th floor Urmi Corporate Park Solaris, Saki Vihar Rd, Opp. L&T Flyover, New Mhada Colony, Budhia Jadhav Wadi, Mumbai, Maharashtra 400072.

CIN: U85320MH2019PTC320566

Telephone:09240250346

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