Zigma Cr 400 Mg Tablet Pr 10

Crescent Formulations Pvt. Ltd.

Pack of 10 Units

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Composition

Carbamazepine (400 Mg)

Zigma Cr 400 Mg Tablet Pr 10 is used to manage epilepsy. It is a single-ingredient anticonvulsant or antiepileptic medicine containing carbamazepine.

This medicine helps control and prevent epileptic seizures. It also helps manage trigeminal and glossopharyngeal neuralgia, conditions that cause severe facial, throat, or ear pain. It also helps manage symptoms of certain types of bipolar disorder when other treatments have not worked well.

Before starting, tell your doctor about your medical conditions and allergies. Tell the doctor about all other medicines, supplements or herbal products you take. Tell your doctor if you are pregnant, planning a pregnancy or breastfeeding. Report persistent or serious side effects to your doctor. Do not stop taking or using the medicine unless your doctor advises you to do so.

Zigma Cr 400 Mg Tablet Pr 10 is used to manage epilepsy.

Uses of Zigma Cr 400 Mg Tablet Pr 10 are:

Epilepsy Management: Helps control and prevent epileptic seizures.
Nerve Pain Relief: Helps manage trigeminal and glossopharyngeal neuralgia, conditions that cause severe facial, throat, or ear pain.
Bipolar Disorder: Helps manage symptoms of certain types of bipolar disorder when other treatments have not worked well.

Follow these instructions while taking Zigma Cr 400 Mg Tablet Pr 10:

Swallow the tablet whole with a full glass of water.
Do not crush, break, or chew the tablet as it may affect how the medicine works.
You can take this medicine with or without food.
Take it at the same time each day to maintain consistent levels in your body.
Never stop taking this medicine suddenly without consulting your doctor.
If you have trouble swallowing the tablet, speak with your doctor about alternatives.

Zigma Cr 400 Mg Tablet Pr 10 is taken orally.

Zigma Cr 400 Mg Tablet Pr 10 may cause some side effects that are usually mild and go away as your body adjusts to the medicine.

A few common side effects of Zigma Cr 400 Mg Tablet Pr 10:

Digestive: nausea, constipation.
Nervous system: dizziness, drowsiness.
Eye: blurred vision.
Unsteady gait: this refers to difficulty walking steadily or maintaining balance while walking.

If any side effect does not improve or becomes serious, speak to your doctor. Do not stop taking the medicine unless your doctor advises you to do so.

Management Of Side Effects:

Most side effects are temporary and generally harmless, which resolve on discontinuing the use of Zigma Cr 400 Mg Tablet Pr 10. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

Here are some ways to manage common side effects:

Nausea: Taking this medicine with food can help reduce feelings of sickness.
Drowsiness: Consider taking Zigma Cr 400 Mg Tablet Pr 10 at bedtime to minimize the impact of drowsiness on your daily activities.

Zigma Cr 400 Mg Tablet Pr 10 contains carbamazepine (400 mg), which works on the body as follows:

Stabilises nerve membranes: Carbamazepine reduces the abnormal electrical activity in your brain by blocking sodium channels in nerve cells, which helps prevent the rapid firing of nerve impulses that cause seizures.
Inhibits nerve signals: It decreases the transmission of pain signals along certain nerve pathways, particularly in the trigeminal nerve, which helps reduce the severe facial pain associated with trigeminal neuralgia.
Regulates brain chemistry: Carbamazepine helps maintain a balance of certain chemicals in your brain, which contributes to its effectiveness in managing both seizures and mood disorders like bipolar disorder.
Prevents seizure spread: It stops seizure activity from spreading to other parts of the brain, helping to limit the severity and duration of seizure episodes.

Pregnancy

Caution is advised while taking Zigma Cr 400 Mg Tablet Pr 10 if you are pregnant. This medicine may potentially harm an unborn baby and could lead to birth defects. It should only be used during pregnancy if your doctor determines that the benefits clearly outweigh the risks.

Breastfeeding

Caution is advised while taking Zigma Cr 400 Mg Tablet Pr 10 if you are breastfeeding. This medicine can pass into breast milk and might cause drowsiness and skin reactions in nursing infants. Discuss with your doctor before using this medicine while breastfeeding.

Alcohol

You should avoid consuming alcohol while taking Zigma Cr 400 Mg Tablet Pr 10. Alcohol may increase drowsiness and dizziness caused by this medicine, making activities like driving more dangerous. It may also reduce the effectiveness of the medicine.

Liver

Caution is advised while taking Zigma Cr 400 Mg Tablet Pr 10 if you have liver problems. This medicine is processed by your liver and may affect liver function. If you have any history of liver disease, inform your doctor before starting this medicine.

Kidney

Caution is advised before using Zigma Cr 400 Mg Tablet Pr 10 if you have a history of any kidney problems. It is a good idea to consult your doctor before taking this medicine.

Use In Driving And Operating Machinery

Take care while driving or operating machinery when using Zigma Cr 400 Mg Tablet Pr 10. This medicine may cause dizziness, drowsiness, and blurred vision, which could affect your ability to concentrate. Avoid these activities if you experience such side effects.

Allergy

Do not take Zigma Cr 400 Mg Tablet Pr 10 if you are allergic to carbamazepine or similar medicines. Tell your doctor about any previous allergic reactions to medicines. Serious skin rashes can occur, which might need immediate medical attention.

Children

Caution is advised while giving Zigma Cr 400 Mg Tablet Pr 10 to children. The dosage for children is different and must be carefully calculated by your doctor based on the child's weight and condition. Always follow your doctor's instructions precisely.

Older Patients

Older patients should take Zigma Cr 400 Mg Tablet Pr 10 under medical supervision as they may be more sensitive to its side effects. Your doctor might start with a lower dose and gradually increase it. Older patients might also have liver and kidney issues that require dosage adjustments.

Drug-Drug Interactions

Zigma Cr 400 Mg Tablet Pr 10 can interact with the following medicines:

Anticonvulsants: Other seizure medicines like phenytoin or valproic acid may decrease the effectiveness of carbamazepine or increase side effects when taken together.
Antibiotics: Medicines like erythromycin or doxycycline can increase carbamazepine levels in your blood, potentially leading to toxicity.
Antidepressants: When taken with certain mood medicines, Zigma Cr 400 Mg Tablet Pr 10 may reduce their effectiveness or increase side effects.
Blood thinners: Carbamazepine can reduce the effectiveness of warfarin, requiring closer monitoring of your blood clotting levels.
Thyroid medicines: This medicine may decrease the amount of thyroid medication in your body, affecting thyroid function.

Drug-Food Interactions

Zigma Cr 400 Mg Tablet Pr 10 can interact with certain foods:

Grapefruit and grapefruit juice: Grapefruit and grapefruit juice can increase carbamazepine levels in your blood. Avoid consuming grapefruit or its juice while taking this medicine as it may increase the risk of side effects.

Drug-Disease Interactions

Zigma Cr 400 Mg Tablet Pr 10 may interact with the following diseases:

Heart disease: This medicine may worsen existing heart conditions, especially if you have a history of heart rhythm problems.
Liver problems: Carbamazepine is processed by the liver and may cause additional strain in patients with liver disease.
Blood disorders: This medicine may worsen certain blood conditions like anaemia or increase the risk of developing blood cell abnormalities.
Glaucoma: Zigma Cr 400 Mg Tablet Pr 10 may increase pressure in the eye, potentially worsening glaucoma symptoms.
Thyroid disorders: This medicine can affect thyroid hormone levels, requiring closer monitoring if you have thyroid problems.

Daily Dose

The daily dose of Zigma Cr 400 Mg Tablet Pr 10 should be taken as prescribed by your doctor. The dosage may vary based on your condition's severity and your response to treatment. Always follow the prescribed dosage and never exceed it without consulting your doctor.

Over Dose

Taking too many of this medication may cause increased dizziness, drowsiness, nausea, vomiting, unsteady walking, blurred vision, and confusion. You might also experience irregular heartbeat. Contact your doctor if you suspect an overdose has occurred.

Missed Dose

If you forget to take Zigma Cr 400 Mg Tablet Pr 10, take it as soon as you remember. If it's nearly time for your next dose, skip the missed one and continue with your regular schedule. Never take a double dose to make up for a missed one.

Follow these instructions while storing Zigma Cr 400 Mg Tablet Pr 10:

Store Zigma Cr 400 Mg Tablet Pr 10 at temperatures not exceeding 30°C.
Store in the original packaging to protect from light and moisture.
Keep all medicines out of sight and reach of children.
Do not use this medicine after the expiry date printed on the package.

Regular sleep schedule: Maintain consistent sleep and wake times to help reduce seizure triggers, as sleep deprivation can worsen epilepsy symptoms.
Stress management: Practice relaxation techniques like deep breathing or gentle yoga to help manage stress, which can be a trigger for seizures and worsen neuralgia pain.

Fact Box

Dosage Forms Available	Extended-release tablet
Habit Forming	No
Ailment	Epilepsy, trigeminal neuralgia, bipolar disorder
Drug Category	Nerve stabiliser
Therapeutic Category	Anticonvulsant/antiepileptic

What is Zigma Cr 400 Mg Tablet Pr 10 used for?

Zigma Cr 400 Mg Tablet Pr 10 manages epilepsy, trigeminal neuralgia (severe facial pain), and certain types of bipolar disorder. It works by stabilising electrical activity in your brain.

How does Zigma Cr 400 Mg Tablet Pr 10 work in the body?

It reduces abnormal electrical activity in your brain. This helps control seizures and blocks pain signals in nerve conditions like trigeminal neuralgia (facial nerve pain).

Can I take Zigma Cr 400 Mg Tablet Pr 10 with other medicines?

You should inform your doctor about all medicines you take. Carbamazepine can interact with antibiotics, contraceptives, blood thinners, and other seizure medicines.

What precautions should I take while using this medicine?

Inform your doctor about any heart, liver, or kidney problems, blood disorders, glaucoma, or thyroid issues before taking this medicine. Regular blood tests may be needed.

What side effects might I experience?

Common side effects include dizziness, drowsiness, nausea, blurred vision, and constipation. Serious side effects like severe skin rash require immediate medical attention.

Can I use Zigma Cr 400 Mg Tablet Pr 10 during pregnancy?

This medicine should be used during pregnancy only if clearly necessary. Consult your doctor as it may potentially affect your unborn baby.

How should I take Zigma Cr 400 Mg Tablet Pr 10?

Take it exactly as prescribed, at the same time daily. Swallow the tablet whole with water—do not crush or chew it as this affects its extended-release properties.

Last Updated On 09 Sep. 2026 | 1:06PM (IST)

Certified Content

Written by

Ashmita Borgohain

Medical Content Writer | 14 years

MSc (Applied Genetics)

Reviewed by

Dr. Chhavi Rosha

Medical Content Writer | 10 years

BAMS, FMC, MD Resident

Check out Editorial Policy

Manufacturer details

Crescent Tower, #4-7-11/4/C Raghavendra Nagar, Nacharam Hyderabad 500076 TS INDIA

Country of origin: INDIA

Expiry on or after: January 2027

In case of any issues, contact us:

support@truemeds.in|09240250346

Address: 6th floor, Urmi Corporate Park Solaris, Saki Vihar Road, Andheri East, Mumbai 400071

References

Carbamazepine: MedlinePlus drug information. (n.d.). https://medlineplus.gov/druginfo/meds/a682237.html
DailyMed - CARBAMAZEPINE tablet. (n.d.). https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=25cca2b1-9020-4d8a-bc22-b8063e57f9e1
Maan, J. S., Duong, T. V. H., & Saadabadi, A. (2023, July 10). Carbamazepine. StatPearls - NCBI Bookshelf. https://www.ncbi.nlm.nih.gov/books/NBK482455/
PubChem. (n.d.-l). Carbamazepine. PubChem. https://pubchem.ncbi.nlm.nih.gov/compound/Carbamazepine
Website, N. (2024f, October 31). Carbamazepine. nhs.uk. https://www.nhs.uk/medicines/carbamazepine/
U.S. Food and Drug Administration. (n.d.). Carbamazepine oral ER cap. https://www.accessdata.fda.gov/drugsatfda_docs/psg/Carbamazepine_Oral%20ER%20cap_20712_RV03-15.pdf

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Disclaimer

We, at Truemeds make a diligent attempt to deliver accurate, expert- drafted and thoroughly reviewed medicine related information to our consumers. However, it should, by no means, be considered a substitute for prescription from a certified doctor or a trustworthy doctor-patient relationship. In fact we detest any form of self medication without expert advice. The sole purpose of the information on our portal is to educate our consumers, which helps improve the communication between a doctor and a patient. The information by no means is complete in its entirety and should not be used to diagnose or treat any medical condition. No amount of information can replace the experience and expertise of a doctor, therefore his/her advice always holds priority and should be followed appropriately.

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