CompositionRenocrit 4000 Injection is used to treat anaemia associated with chronic kidney disease, especially in people undergoing dialysis. It stimulates red blood cell production, improving oxygen delivery in the body and reducing tiredness, weakness and breathlessness.
It contains epoetin alfa, a man-made version of a hormone that stimulates red blood cell production. It is also used in kidney-related anaemia in people not yet on dialysis, and in adults with anaemia caused by chemotherapy. It is given by injection under medical supervision, with the dose adjusted based on your haemoglobin levels.
Staying well hydrated and eating a balanced diet with adequate iron intake, as advised by your doctor, support red blood cell production alongside this treatment.
Before this medicine is given, tell your doctor about any high blood pressure, heart disease, seizures or other medicines you take. Your blood pressure and haemoglobin levels will be monitored regularly during treatment, as this medicine can raise blood pressure.
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Renocrit 4000 Injection 0.4Ml
Zydus Lifesciences Limited
Pre-filled syringe of 0.40 ML
Old MRP ₹1307
MRP ₹1225.31
₹980.25
₹3063.27/ML
100% genuine medicines
Safe & secure payments
Safe packing and storage
Non returnable productView policy
Prescription required for this medicine
Store in refrigerator or (2° - 8° C) Do Not Freeze
About Renocrit 4000 Injection 0.4Ml
Uses of Renocrit 4000 Injection 0.4Ml
Renocrit 4000 Injection is used in people with chronic kidney disease, both on and off dialysis, and in adults with chemotherapy-related anaemia, to raise red blood cell levels.
Uses of Renocrit 4000 Injection are:
• Kidney-Related Anaemia: Treats anaemia caused by chronic kidney disease in dialysis and non-dialysis patients.
• Chemotherapy-Related Anaemia: Manages anaemia in adults receiving chemotherapy for certain cancers.
• Surgical Blood Support: Helps reduce the need for blood transfusions in patients scheduled for elective surgery.
Directions for Use of Renocrit 4000 Injection 0.4Ml
- This injection is administered by a healthcare professional.
- Follow your doctor’s instructions regarding hydration and other supportive measures.
Route of Administration
Renocrit 4000 Injection is administered subcutaneously (under the skin) or intravenously (into a vein).
Side Effects of Renocrit 4000 Injection 0.4Ml
Renocrit 4000 Injection may cause side effects during or after treatment, but not everyone gets them.
A few common side effects of Renocrit 4000 Injection are:
• Neurological: Headache.
• Digestive: Feeling sick (nausea) and vomiting.
• Cardiovascular: High blood pressure, which may require monitoring during treatment.
• Injection Site: Pain, redness or swelling at the injection site.
If side effects do not improve or become serious, speak to your doctor or nurse right away.
Management Of Side Effects:
Most side effects are temporary and generally harmless, which resolve on discontinuing the use of this Injection. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.
- Nausea or vomiting: Stay hydrated and consume small, frequent meals.
- Injection site reactions: Apply a cold compress to the injection site to alleviate swelling or pain.
- Hypertension: Monitor blood pressure regularly to manage hypertension effectively.
How Renocrit 4000 Injection 0.4Ml Works?
Renocrit 4000 Injection contains Recombinant Human Erythropoietin Alfa (4000 IU), which acts as follows:
- It mimics the action of erythropoietin, a natural hormone produced by the kidneys. It works by stimulating the bone marrow to produce red blood cells, treating anaemia caused by reduced erythropoietin levels.
Safety Measures & Warnings
Pregnancy
Discuss the potential risks and benefits with your doctor before using Renocrit 4000 Injection during pregnancy.
Breastfeeding
It is not known whether erythropoietin alfa passes into breast milk. Inform your doctor before taking this injection.
Alcohol
Limit alcohol consumption when taking Renocrit 4000 Injection, as it may exacerbate anaemia and other health conditions.
Liver
Patients with liver diseases should use Renocrit 4000 Injection cautiously. Regular liver function tests are recommended.
Kidney
This medication is primarily used in kidney disease patients. Regular monitoring of kidney function is crucial during treatment.
Use In Driving And Operating Machinery
Avoid driving or operating machinery if you experience dizziness, headache, or fatigue after the injection.
Allergy
If you have a known allergy to erythropoietin or any ingredients in Renocrit 4000 Injection, avoid using this medication and inform your doctor immediately.
Children
Renocrit 4000 Injection is not recommended for children uner 18 years unless specifically prescribed by a doctor.
Older Patients
Older patients may require careful monitoring due to a higher risk of side effects, especially cardiovascular events.
Interactions of Renocrit 4000 Injection 0.4Ml
Drug-Drug Interactions
Renocrit 4000 Injection can interact with medications including:
- Antihypertensives such as propanolol and atenolol: Recombinant human erythropoietin alfa may increase blood pressure and thereby reduce the effectiveness of antihypertensives.
- Iron Supplements: Enhances efficacy when used together. Monitor iron levels regularly.
Drug-Food Interactions
No significant food interactions are known, but maintaining a balanced diet can support overall treatment.
Drug-Disease Interactions
Renocrit 4000 Injection can interact with conditions including:
- Hypertension: This injection can increase blood pressure. It must be controlled before starting treatment.
- Thromboembolic Events: Patients with a history of blood clots require careful monitoring.
Dosage of Renocrit 4000 Injection 0.4Ml
Daily Dose
The daily dosage of Renocrit 4000 Injection depends on your condition and response to treatment. Your doctor will determine the appropriate dose based on your haemoglobin levels and therapeutic goals.
Over Dose
Overdosing of this injection may lead to high haemoglobin levels, increasing the risk of cardiovascular complications. Seek immediate medical attention if an overdose is suspected.
Missed Dose
If a dose is missed, consult your doctor for further instructions. Do not double the dose.
Storage
- Store at 2°C to 8°C. Do not freeze.
- Protect from light and keep the syringe in its original packaging.
- Keep out of reach of children.
Special Dietary And Lifestyle Recommendation
- Maintain a diet rich in iron, folic acid, and vitamin B12 to support red blood cell production.
- Engage in light to moderate exercise to enhance energy levels but avoid overexertion.
Fact Box
| Dosage Forms Available | Injection |
| Habit Forming | No |
| Ailment | Anaemia in chronic kidney disease, chemotherapy-induced anaemia, surgical anaemia |
| Drug Category | Erythropoiesis-Stimulating Agent (ESA) |
| Therapeutic Category | Anti-anaemic |
Frequently Asked Questions (FAQs)
What is Renocrit 4000 Injection used for?
This injection is used to treat anaemia caused by chronic kidney disease, chemotherapy, or surgery.
How does Renocrit 4000 Injection work?
This injection stimulates the production of red blood cells by mimicking the natural hormone erythropoietin.
Can I use Renocrit 4000 Injection during pregnancy?
Consult your doctor to evaluate the risks and benefits of using this medication during pregnancy.
What are the side effects of Renocrit 4000 Injection?
The common side effects include headache, nausea, and hypertension.
How should I store Renocrit 4000 Injection?
Store it at 2°C to 8°C, away from light and out of reach of children.
Can I drink alcohol while on Renocrit 4000 Injection?
Limit alcohol consumption to avoid complications related to anaemia. Always discuss with your doctor.
What should I do if I miss a dose of Renocrit 4000 Injection?
Contact your healthcare provider for advice. Never double the dose to make up for a missed one.
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Manufacturer details
Country of origin: INDIA
References
- Beta, E. (n.d.). Recormon pre-filled syringes. Roche.Com. Retrieved January 15, 2025, from https://assets.roche.com/f/170883/x/543f83bbb2/recormon-pi-feb-2022.pdf
- (N.d.). Gov.Rw. Retrieved January 15, 2025, from https://rwandafda.gov.rw/wp-content/uploads/2024/02/REPOITIN
- Binocrit 1 000 IU/0.5 mL solution for injection.(N.d.). Europa.Eu. Retrieved January 15, 2025, from https://www.ema.europa.eu/en/documents/product-information/binocrit-epar-product-information_en.pdf
Disclaimer
We, at Truemeds make a diligent attempt to deliver accurate, expert- drafted and thoroughly reviewed medicine related information to our consumers. However, it should, by no means, be considered a substitute for prescription from a certified doctor or a trustworthy doctor-patient relationship. In fact we detest any form of self medication without expert advice. The sole purpose of the information on our portal is to educate our consumers, which helps improve the communication between a doctor and a patient. The information by no means is complete in its entirety and should not be used to diagnose or treat any medical condition. No amount of information can replace the experience and expertise of a doctor, therefore his/her advice always holds priority and should be followed appropriately.
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