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Recombinant Human Erythropoietin Alfa

Uses of Recombinant Human Erythropoietin Alfa

Recombinant Human Erythropoietin Alfa is used to manage anaemia caused by low levels of the natural hormone erythropoietin.

Recombinant Human Erythropoietin Alfa is commonly used for:

• Anaemia in chronic kidney disease: Increases red blood cell production in patients with reduced kidney function.
• Chemotherapy-related anaemia: Manages anaemia caused by myelosuppressive cancer treatment.
• Zidovudine-related anaemia in HIV: Treats anaemia linked to zidovudine therapy in people with HIV.
• Reducing blood transfusion needs: Lowers the requirement for blood transfusions in patients undergoing certain elective, non-cardiac, non-vascular surgical procedures.

Side effects of Recombinant Human Erythropoietin Alfa

  • Hypertension (high blood pressure)

  • Headache

  • Nausea

  • Vomiting

  • Diarrhoea

How Recombinant Human Erythropoietin Alfa works

Recombinant Human Erythropoietin Alfa is a synthetic form of erythropoietin, a hormone that stimulates the body to produce red blood cells.

It works by binding to receptors on immature red blood cells in the bone marrow. This binding signals these cells to multiply and mature into fully functional, oxygen-carrying red blood cells.

By increasing red blood cell production, Recombinant Human Erythropoietin Alfa helps correct anaemia and improve the oxygen-carrying capacity of the blood.

Certified content

Written By

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Dr. Michelle FrankMedical Content Writer| 10 years

Doctor of Medicine

Reviewed By

Dr. Chhavi Rosha
Dr. Chhavi RoshaMedical Content Writer| 10 years

BAMS, FMC, MD Resident

Expert Advice

Dosage Forms Available

  • Recombinant Human Erythropoietin Alfa is available for use through the intravenous (in the vein) or subcutaneous (under the skin) routes (injection).

Age and Dose Restrictions

  • This medication is suitable for both adults and children, as recommended by the doctor.

Contraindications

  • Recombinant Human Erythropoietin Alfa is contraindicated in patients with allergy to any component of the product.

  • It is also contraindicated in patients with uncontrolled hypertension.

Other Medications to Avoid

  • Recombinant Human Erythropoietin Alfa can interact with antihypertensive medications (such as atenolol and metoprolol).

Overdose and Missed Dose

  • Taking more than the prescribed dose may raise the percentage of red blood cells in the blood (haematocrit) to unsafe levels, increasing the risk of blood clots. This requires immediate medical attention.
  • If you miss an appointment for your Recombinant Human Erythropoietin Alfa injection, contact your doctor or healthcare provider as soon as possible to arrange your next dose. Do not take a double dose to make up for a missed dose.

Management of Side Effects

Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

  • For managing headaches, try to rest and relax.

  • If you experience nausea, eat little and often, and stick to simple meals.

  • In case of injection site pain or irritation, try applying a cold pack to the area.

Use in Driving and Operating Machinery

  • Recombinant Human Erythropoietin Alfa may cause side effects such as dizziness or fainting. If affected, avoid driving or operating heavy machinery.

Use in Pregnancy and Lactation

  • It is advised to consult your doctor before using this medication if you are pregnant or breastfeeding.

Caution in Other Conditions

  • Patients with a history of seizures, renal issues, high blood pressure or thrombotic events should exercise caution when using Recombinant Human Erythropoietin Alfa.

  • Close monitoring of blood pressure and haematocrit levels is essential for these patients.

Special Dietary and Lifestyle Recommendations

  • Stay well hydrated, especially before and after treatment.

  • Regular monitoring of blood pressure and blood sugar levels is recommended.

Frequently asked questions

Recombinant Human Erythropoietin Alfa is not directly associated with affecting fertility. However, consult your doctor for detailed information regarding your case.

The frequency of administering Recombinant Human Erythropoietin Alfa is decided by the doctor based on the patient's health condition and response to treatment.

After subcutaneous injection, peak levels of Recombinant Human Erythropoietin Alfa occur within 5-24 hours post-dose. The actual time may vary depending on individual patient factors.

The best time to administer Recombinant Human Erythropoietin Alfa is decided by the doctor. It is usually administered through intravenous or subcutaneous injection under medical supervision.

Recombinant Human Erythropoietin Alfa is a prescription medicine. It is not available over the counter.

Switching from Recombinant Human Erythropoietin Alfa to a natural alternative, especially mid-treatment, is not recommended. It should only be done under the guidance of your doctor.

Recombinant Human Erythropoietin Alfa is not directly associated with affecting sleep patterns. However, if you are experiencing sleep issues, it is recommended to consult your doctor as it could be a sign of underlying complications or side effects.

Terms & Conditions

List of medicines for Recombinant Human Erythropoietin Alfa

Epofit Injection 0.5Ml
Epofit Injection 0.5Ml
Intas Pharmaceuticals Ltd
Pack of 0.50 ML
₹1765.5
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20% OFF
Renemia 10000Iu Injection 1Ml
Renemia 10000Iu Injection 1Ml
Rene Life Science
Pack of 1 ML
₹1725
MRP ₹2156.25
20% OFF
Renocrit 10000 Injection 1Ml
Renocrit 10000 Injection 1Ml
Zydus Lifesciences Limited
Pack of 1 ML
₹1653.9
MRP ₹2067.38
20% OFF
Renocrit 4000 Injection 0.4Ml
Renocrit 4000 Injection 0.4Ml
Zydus Lifesciences Limited
Pack of 0.40 ML
₹980.25
MRP ₹1225.31
20% OFF
Anfoe 10000Iu Injection 1Ml
Anfoe 10000Iu Injection 1Ml
La Renon Healthcare Private Limited
Pack of 1 ML
₹1681.5
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20% OFF
Erypeg 50 Injection 0.3Ml
Erypeg 50 Injection 0.3Ml
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Pack of 0.30 ML
₹4035
MRP ₹5043.75
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Zyrop 10000 Injection 1
Zyrop 10000 Injection 1
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Pack of 1 UNITS
₹1587.6
MRP ₹2116.8
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Zyrop 10000 Injection 6Ml
Zyrop 10000 Injection 6Ml
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Pack of 6 UNITS
₹1653.9
MRP ₹2067.37
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