Pirox 20 MG Injection 1 ML is used to manage pain and inflammation in conditions such as rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, acute musculoskeletal injuries, and postoperative pain. It belongs to the NSAID group and provides rapid pain relief when oral medicines are unsuitable. This injection helps reduce swelling, stiffness, and discomfort. The dosage and duration are decided by a doctor. Inform your doctor about stomach, heart, kidney issues, or other medicines before use.
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Pirox 20 MG Injection 1 ML
Pack of 1 ML
Old MRP ₹18.9
MRP ₹17.72
₹14.18
₹17.72/ML
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CompositionAbout Pirox 20 MG Injection 1 ML
Uses of Pirox 20 MG Injection 1 ML
Pirox 20 MG Injection 1 ML is used to manage inflammatory and painful conditions such as rheumatoid arthritis, osteoarthritis, and ankylosing spondylitis. It is also used to control acute musculoskeletal disorders and relieve postoperative pain by reducing inflammation, swelling, and discomfort.
Directions for Use of Pirox 20 MG Injection 1 ML
This injection should be administered only by a healthcare practitioner.
Ensure the site of injection is clean and dry before administering.
This injection should be administered slowly to minimise any possible irritation at the site.
Always consult your doctor for specific advice on how frequently and when to administer Pirox Injection.
Route of Administration
Pirox Injection is administered via an intramuscular route.
Side Effects of Pirox 20 MG Injection 1 ML
Pirox 20 MG Injection 1 ML may have common side effects such as gastrointestinal disturbances including nausea, vomiting, diarrhoea, and abdominal pain, along with headache, dizziness, skin rash, swelling, and injection-site reactions.
Management Of Side Effects:
Most side effects are temporary and generally harmless, which are resolved by discontinuing the use of Pirox Injection. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.
Here are some general guidelines for managing common side effects:
Gastrointestinal disturbances: Try taking meals before administering Pirox Injection to help manage these symptoms.
Injection site reactions: Administering Pirox Injection slowly might reduce local irritation at the injection site.
How Pirox 20 MG Injection 1 ML Works?
Pirox Injection contains piroxicam (20 mg), which works on your body in the following ways:
Inhibits Prostaglandin Synthesis: Piroxicam works by blocking the activity of cyclooxygenase (COX) enzymes in your body. These enzymes play a key role in producing prostaglandins, which cause inflammation and pain.
Reduces Inflammation and Pain: By inhibiting COX enzymes and subsequently reducing prostaglandin production, piroxicam effectively manages inflammation and pain. This can provide relief from discomfort associated with various inflammatory conditions.
Safety Measures & Warnings
Pregnancy
Pirox Injection is contraindicated during pregnancy, especially in the third trimester. If you are pregnant or planning to conceive, make sure to discuss this with your doctor before starting this medicine.
Breastfeeding
Pirox Injection is contraindicated for breastfeeding/lactating women. Consult your doctor to understand the potential risks and benefits.
Alcohol
While using Pirox Injection, it's advised to limit your alcohol intake as it may increase the risk of stomach issues. Discuss any concerns with your doctor.
Liver
Caution is advised while taking Pirox Injection in cases of mild to moderate liver impairment. This medicine may affect liver function. If you have liver problems, discuss them with your doctor before starting Pirox Injection.
Kidney
You should exercise caution before using Pirox Injection if you have a history of kidney problems. It is a good idea to consult your doctor before taking this medicine.
Use In Driving And Operating Machinery
Pirox Injection may cause dizziness and affect alertness. Be cautious while driving or operating machinery until you know how this medicine affects you.
Allergy
If you have known allergies to piroxicam or other NSAIDs, Pirox Injection is contraindicated. Make sure you inform your doctor about any such allergies.
Children
Pirox Injection should not be given to children under 18 years of age without medical advice. Always consult your doctor before giving any medicine to a child.
Older Patients
Older patients should take Pirox Injection under medical supervision, as they may be more susceptible to its side effects. Caution is advised if patients are above 70 years of age, as they may have underlying liver and kidney issues and might be on other medication. Your doctor will guide you based on your health status.
Interactions of Pirox 20 MG Injection 1 ML
Drug-Drug Interactions
Pirox Injection interacts with the following medicines:
Other NSAIDs: Medicines like aspirin and ibuprofen can increase the risk of gastrointestinal bleeding or ulceration when taken with Pirox Injection.
Anticoagulants: Medicines like warfarin may interact with Pirox Injection, potentially leading to an increased risk of bleeding.
ACE Inhibitors and Angiotensin Receptor Blockers: These medicines, such as benazepril, captopril and losartan, may reduce the effectiveness of Pirox Injection in reducing inflammation and relieving pain.
Diuretics: Pirox Injection can decrease the diuretic effect of medicines like furosemide and hydrochlorothiazide.
Antimanic Agent: The blood levels of lithium may increase when used with Pirox Injection, increasing the risk of lithium toxicity.
Antimetabolites and Immunosuppressants: Medicines like methotrexate and cyclosporine when used with Pirox Injection can increase their blood levels, leading to increased toxicity caused by them.
Drug-Food Interactions
Pirox Injection does not have any known food interactions.
Drug-Disease Interactions
Pirox Injection interacts with the following diseases:
Gastrointestinal Disorders: Patients who have a history of gastrointestinal disorders should exercise caution as Pirox Injection could exacerbate their condition.
Cardiovascular Disease: Patients suffering from cardiovascular diseases need to be careful as Pirox Injection can increase the risk of heart attack or stroke.
Renal Impairment: In patients with kidney impairment, Pirox Injection may worsen kidney function.
Liver Dysfunction: People with liver disease should use Pirox Injection cautiously as it could potentially worsen their condition.
Dosage of Pirox 20 MG Injection 1 ML
Daily Dose
Your doctor should determine the dosage of Pirox Injection based on your specific condition and response. Strictly adhere to this dosage and avoid any alterations without consultation.
Over Dose
Accidental overdose may lead to common side effects like nausea, diarrhoea, or dizziness. If these symptoms persist or worsen, it's crucial to inform your doctor promptly.
Missed Dose
In case of a missed dose, get it administered as soon as you remember. If it's near the time for the next dose, skip the missed one and continue with your regular schedule. Always consult your doctor before adjusting the dosage.
Storage
Store Pirox Injection at normal room temperature, ideally between 15-30°C.
Keep it protected from direct sunlight and moisture.
Keep this medicine out of reach and sight of children.
Make sure to use the Pirox Injection within its expiry date.
Special Dietary And Lifestyle Recommendation
If you have rheumatoid arthritis, osteoarthritis or ankylosing spondylitis - conditions managed by Pirox Injection - including omega-3 fatty acids in your diet can be beneficial. These are found in fish like salmon and mackerel and help reduce inflammation.
Regular gentle physical activity, like swimming or walking, can help keep your joints flexible and reduce the discomfort of arthritis. However, avoid strenuous activities that may strain your joints.
Fact Box
| Dosage Forms Available | Injection |
| Habit Forming | No |
| Ailment | Rheumatoid Arthritis, Osteoarthritis, Ankylosing Spondylitis |
| Drug Category | Prostaglandin Synthesis Inhibitor |
| Therapeutic Category | Nonsteroidal Anti-Inflammatory |
Frequently Asked Questions (FAQs)
What is Pirox Injection used for?
Pirox Injection is used to manage various inflammatory conditions like rheumatoid arthritis, osteoarthritis, and ankylosing spondylitis, as well as postoperative pain.
How does Pirox Injection work?
It works by inhibiting the production of prostaglandins - substances that cause inflammation and pain - thus reducing these symptoms.
Can Pirox Injection interact with other medicines?
Yes, Pirox Injection can interact with certain medicines. Always inform your doctor about all medications you are taking before starting Pirox Injection.
What are some side effects of Pirox Injection?
Some common side effects include gastrointestinal disturbances, headache, dizziness, rash, and injection site reactions. Serious side effects are rare but can occur.
Who should avoid using Pirox Injection?
Individuals allergic to piroxicam or other NSAIDs, with active peptic ulcer disease or gastrointestinal bleeding, should avoid using Pirox Injection.
Is Pirox Injection safe during pregnancy and breastfeeding?
No, Pirox Injection should not be used during pregnancy, especially in the third trimester, or while breastfeeding due to potential risks.
How should I store Pirox Injection?
Store it at room temperature (15-30°C), protect it from light and do not freeze. Once opened, use immediately and discard any unused portion.
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Manufacturer details
Cipla House, Peninsula Business Park, Ganpatrao Kadam Marg, Lower Parel, Mumbai-400013
Country of origin: INDIA
Country of origin: INDIA
Expiry on or after: July 2026
In case of any issues, contact us:
support@truemeds.in|09240250346
Address: 6th floor, Urmi Corporate Park Solaris, Saki Vihar Road, Andheri East, Mumbai 400071
References
MedlinePlus. (n.d.). Piroxicam. Retrieved April 1, 2024, from https://medlineplus.gov/druginfo/meds/a684045.html
National Center for Biotechnology Information (2024). PubChem Compound Summary for CID 54676228, Piroxicam. Retrieved November 17, 2024 from https://pubchem.ncbi.nlm.nih.gov/compound/Piroxicam
Mostafa, G. A. E., Al-Dosseri, A. S., & Al-Badr, A. A. (2020). Piroxicam. Profiles of drug substances, excipients, and related methodology, 45, 199–474. https://doi.org/10.1016/bs.podrm.2019.10.007
Saganuwan S. A. (2017). Piroxicam: Source for Synthesis of Central Nervous System (CNS) Acting Drugs. Central nervous system agents in medicinal chemistry, 17(2), 135–140. https://doi.org/10.2174/1871524916666160719102335
Guttadauria M. (1986). The clinical pharmacology of piroxicam. Acta obstetricia et gynecologica Scandinavica. Supplement, 138, 11–13. https://doi.org/10.3109/00016348509157060
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We, at Truemeds make a diligent attempt to deliver accurate, expert- drafted and thoroughly reviewed medicine related information to our consumers. However, it should, by no means, be considered a substitute for prescription from a certified doctor or a trustworthy doctor-patient relationship. In fact we detest any form of self medication without expert advice. The sole purpose of the information on our portal is to educate our consumers, which helps improve the communication between a doctor and a patient. The information by no means is complete in its entirety and should not be used to diagnose or treat any medical condition. No amount of information can replace the experience and expertise of a doctor, therefore his/her advice always holds priority and should be followed appropriately.
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