Nucoxia Xp Tablet 5

Zydus Healthcare Ltd

Strip of 5 Units

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Composition

Etoricoxib (120 Mg)

Nucoxia XP Tablet is used to treat pain, inflammation and stiffness caused by conditions such as osteoarthritis, rheumatoid arthritis, ankylosing spondylitis and gout.

It contains etoricoxib, a selective COX-2 inhibitor that blocks the chemicals responsible for pain and swelling in the joints, while being gentler on the stomach than older pain relievers. Take it exactly as prescribed by your doctor.

Gentle exercise, maintaining a healthy weight and applying warm or cold compresses as advised can help support joint mobility alongside this medicine.

Inform your doctor of any history of heart or kidney problems before starting this tablet. Tell your doctor about any other medicines you take, and report any chest pain, swelling or breathlessness promptly.

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Nucoxia XP Tablet is used to treat pain, inflammation and stiffness in conditions such as osteoarthritis, rheumatoid arthritis and gout, and to relieve pain following dental or minor surgeries.

Uses of Nucoxia XP Tablet are:

Osteoarthritis and Rheumatoid Arthritis: Reduces joint pain, swelling and stiffness.
Ankylosing Spondylitis and Gout: Eases pain and inflammation associated with these conditions.
Post-Surgical Pain: Relieves short-term pain following dental or minor surgeries.

Here are some guidelines to follow while taking Nucoxia Xp Tablet 5:

The tablet should be swallowed whole with a glass of water.
Avoid breaking, crushing, or chewing the tablet.
Always stick to the recommended dosage and never exceed it without consulting your doctor first.
Consult your doctor before deciding to stop taking this medicine.

Nucoxia Xp Tablet 5 is taken orally.

Nucoxia XP Tablet may cause some side effects that are usually mild and go away as your body adjusts to the medicine.

A few common side effects of Nucoxia XP Tablet:

Digestive: Stomach pain, indigestion and loose motions (diarrhoea).
Neurological: Dizziness and headache.
Skin: Rash and itching.
General: Tiredness (fatigue).

If side effects do not improve or become serious, speak to your doctor right away.

Management Of Side Effects:

Most side effects are temporary and generally harmless, which resolve upon discontinuing the use of Nucoxia Xp Tablet 5. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

Here are some general guidelines for managing common side effects:

Abdominal pain: Try taking Nucoxia Xp Tablet 5 with food or milk to help reduce stomach discomfort.
Indigestion: If you have indigestion, take this medicine after meals to lessen this effect.

Nucoxia Xp Tablet 5 contains Etoricoxib (120mg). It works in the body as follows:

COX-2 Inhibition: Etoricoxib functions by blocking a specific enzyme in your body, known as COX-2. This enzyme plays a crucial role in producing substances called prostaglandins that can cause pain and inflammation.
Decrease in Prostaglandins: By inhibiting the activity of COX-2, Etoricoxib effectively reduces the production of pain-causing prostaglandins. As a result, it helps to relieve discomfort and decrease inflammation related to various forms of arthritis.

Pregnancy

Nucoxia Xp Tablet 5 is contraindicated during pregnancy. If you are pregnant or planning to conceive, make sure to discuss this with your doctor before starting this medicine.

Breastfeeding

Nucoxia Xp Tablet 5 is contraindicated for breastfeeding women. Consult your doctor to understand the potential risks and benefits.

Alcohol

Caution is advised while taking Nucoxia Xp Tablet 5 and consuming alcohol. It is best to consult your doctor about alcohol consumption when on this medication.

Liver

Caution is advised while taking Nucoxia Xp Tablet 5 in case of mild to moderate liver impairment. It is not recommended for severe liver diseases. If you have liver problems, discuss them with your doctor before starting Nucoxia Xp Tablet 5. This medicine may affect liver function.

Kidney

Caution is advised before using the Nucoxia Xp Tablet 5 if you have a history of any kidney problems. It's a good idea to consult your doctor before taking this medicine.

Use In Driving And Operating Machinery

As dizziness has been reported with Nucoxia Xp Tablet 5, caution is advised while driving or operating machinery until you know how this medicine affects you.

Allergy

Nucoxia Xp Tablet 5 is contraindicated in patients with known hypersensitivity to etoricoxib or any other ingredient in the tablet. If you've had allergic reactions after taking aspirin or other NSAIDs, discuss it with your doctor before starting this medicine.

Children

Caution is advised while giving Nucoxia Xp Tablet 5 to children under 18 years of age. Always consult your doctor before giving any medicine to a child.

Older Patients

Older patients should take Nucoxia Xp Tablet 5 under medical supervision as they may be more susceptible to its side effects. Caution is advised if patients are above 70 years of age. Older patients might also have liver and kidney issues and might be on other medication. Your doctor will guide you based on your health status.

Drug-Drug Interactions

Nucoxia Xp Tablet 5 interacts with the following medicines:

Other NSAIDs or Salicylates: Nucoxia Xp Tablet 5 can interact with medications like ibuprofen, aspirin or diclofenac, increasing the risk of gastrointestinal toxicity.
Antihypertensive Medicines: ACE inhibitors like enalapril, ARBs like losartan, beta-blockers like atenolol and diuretics like furosemide may see their blood pressure-lowering effect reduced when taken with Nucoxia Xp Tablet 5. Regular monitoring of blood pressure is necessary.
Anticoagulants: If you're taking warfarin or other similar agents alongside Nucoxia Xp Tablet 5, your risk of bleeding may increase. Regular monitoring is required if such a combination is unavoidable.
Antimetabolites: Plasma levels of methotrexate may increase if taken with Nucoxia Xp Tablet 5.
Antimanic Agents: Using medicine like lithium with Nucoxia Xp Tablet 5 could increase the chance of lithium toxicity. Regular monitoring of lithium levels is necessary.

Drug-Food Interactions

No specific food interactions have been reported with Nucoxia Xp Tablet 5.

Drug-Disease Interactions

Nucoxia Xp Tablet 5 interacts with the following diseases:

Liver Disease: Taking this medicine could worsen your condition if you have severe liver dysfunction.
Heart Disease: Those with cardiovascular diseases need to be cautious as this medicine may increase the risk of heart attack and stroke.
Kidney Disease: Individuals with impaired renal function should use this medicine cautiously as it may lead to renal injury or failure.

Daily Dose

You must take your recommended dose of Nucoxia Xp Tablet 5 as directed by your doctor. The dosage might vary depending on individual factors, such as how severe your condition is and how you respond to the medicine. Always stick to your prescribed dosage and never increase it without your doctor's advice.

Over Dose

If you accidentally take more Nucoxia Xp Tablet 5s than prescribed, you might experience symptoms like stomach discomfort or headache. It's important not to panic but to inform your doctor about this incident.

Missed Dose

If you forget to take the Nucoxia Xp Tablet 5 at the specified time, take it as soon as you remember. If it's close to your next dose, skip the missed one and continue with your regular schedule. Don't take an extra dose without consulting your doctor.

Keep the Nucoxia Xp Tablet 5 at room temperature.
Shield it from light and moisture to maintain its effectiveness.
It is crucial to place the medicine out of the reach and sight of children.

If you're managing conditions such as osteoarthritis or rheumatoid arthritis with Nucoxia Xp Tablet 5, consider adopting a balanced diet rich in calcium and vitamin D to support bone health.
Regular low-impact exercise like swimming or cycling can help maintain joint flexibility and reduce stiffness, complementing the action of the Nucoxia Xp Tablet 5. Always consult your doctor before starting any new exercise regimen.

Fact Box

Dosage Forms Available	Tablet
Habit Forming	No
Ailment	Osteoarthritis, Rheumatoid Arthritis, Gout
Drug Category	COX-2 Inhibitor
Therapeutic Category	NSAID

What is the Nucoxia Xp Tablet 5 used for?

Nucoxia Xp Tablet 5 manages pain and stiffness from arthritis, gout, and dental surgery by reducing inflammation in your body.

How does the Nucoxia Xp Tablet 5 work?

It contains etoricoxib, which blocks an enzyme called COX-2, reducing the production of chemicals that cause pain and inflammation.

Can I consume this medicine with food?

Yes, you can take an Nucoxia Xp Tablet 5 with or without food. Consuming it with meals can help minimise stomach discomfort.

What are the side effects of Etoricoxib?

Common side effects include stomach pain, diarrhoea, nausea, dizziness, headache, skin rash and increased blood pressure.

When should I avoid taking Etoricoxib?

Avoid it if you're allergic to etoricoxib or if you have active peptic ulceration, gastrointestinal bleeding or severe liver dysfunction.

Can I use other painkillers with Etoricoxib?

No. Avoid using other NSAIDs or aspirin as it increases the risk of stomach toxicity. Consult your doctor for more information.

How should I store my medicine?

Etoricoxib should be stored at room temperature, protected from moisture and light, and kept out of children's reach.

Last Updated On 18 Sep. 2026 | 7:50AM (IST)

Certified Content

Written by

Dr Nikita Lobo

Medical Content Reviewer | 9 years

BDS, MDS

Reviewed by

Dr. Osama Ahmed

Medical Content Writer | 4 years

Bachelor of Dental Surgery

Check out Editorial Policy

Manufacturer details

Zydus Tower, Satellite Cross Roads, Sarkhej - Gandhinagar Highway, Ahmedabad Ahmedabad GJ 380015 IN

Country of origin: INDIA

Expiry on or after: January 2027

In case of any issues, contact us:

support@truemeds.in|09240250346

Address: 6th floor, Urmi Corporate Park Solaris, Saki Vihar Road, Andheri East, Mumbai 400071

References

Cochrane, D. J., Jarvis, B., & Keating, G. M. (2002). Etoricoxib. Drugs, 62(18), 2637–2651. https://pubmed.ncbi.nlm.nih.gov/12466002/
Brooks, P., & Kubler, P. (2006, March 1). Etoricoxib for arthritis and pain management. PubMed Central (PMC). https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1661646/
Etoricoxib: Uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB01628
Etoricoxib. (2004, May 1). PubMed. https://pubmed.ncbi.nlm.nih.gov/15319795/
National Center for Biotechnology Information (2024). PubChem Compound Summary for CID 123619, Etoricoxib. Retrieved June 7, 2024 from https://pubchem.ncbi.nlm.nih.gov/compound/Etoricoxib

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Disclaimer

We, at Truemeds make a diligent attempt to deliver accurate, expert- drafted and thoroughly reviewed medicine related information to our consumers. However, it should, by no means, be considered a substitute for prescription from a certified doctor or a trustworthy doctor-patient relationship. In fact we detest any form of self medication without expert advice. The sole purpose of the information on our portal is to educate our consumers, which helps improve the communication between a doctor and a patient. The information by no means is complete in its entirety and should not be used to diagnose or treat any medical condition. No amount of information can replace the experience and expertise of a doctor, therefore his/her advice always holds priority and should be followed appropriately.

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