Noxval Chrono 333/145 Mg Tablet 10 is used to control epilepsy (partial and generalised seizures), to manage manic episodes in bipolar disorder, and to help prevent migraine in adults.
It contains sodium valproate, an anticonvulsant and mood stabiliser. It works by calming overactive nerve signals in the brain.
Take it with food as prescribed, and do not stop it suddenly, as this can trigger seizures. Regular blood tests monitor valproate levels and liver function.
This medicine must not be used in pregnancy unless there is no alternative, as it can cause serious birth defects and developmental problems. Women and girls who could become pregnant must use effective contraception as part of a pregnancy prevention programme. Tell your doctor about any liver problems, and report signs of liver trouble (feeling sick, jaundice, unusual tiredness) or unusual bleeding.
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Noxval Chrono 333/145 Mg Tablet 10
Strip of 10 Units
Old MRP ₹100.95
MRP ₹94.64
₹75.71
₹9.46/Units
100% genuine medicines
Safe & secure payments
15 days Easy returns
Prescription required for this medicine
Store Below 30° C
CompositionAbout Noxval Chrono 333/145 Mg Tablet 10
Uses of Noxval Chrono 333/145 Mg Tablet 10
Noxval Chrono 333/145 Mg Tablet 10 is used for epilepsy, bipolar disorder and migraine.
Uses of Noxval Chrono 333/145 Mg Tablet 10 are:
- Epilepsy: Controls and prevents epileptic seizures.
- Bipolar Disorder: Helps manage and stabilise manic episodes.
- Migraine Prevention: Helps reduce the frequency of migraines.
Directions for Use of Noxval Chrono 333/145 Mg Tablet 10
Here's how to take Noxval Chrono 333/145 Mg Tablet 10:
- Swallow the tablet whole with a glass of water.
- Don't crush or chew the tablet.
- Follow your doctor's instructions on when to take the tablet.
- Never take more than your doctor has prescribed.
- If you have any questions, consult your doctor.
Route of Administration
Noxval Chrono 333/145 Mg Tablet 10 is taken orally.
Side Effects of Noxval Chrono 333/145 Mg Tablet 10
Noxval Chrono 333/145 Mg Tablet 10 may cause side effects, but not everyone gets them.
A few common side effects of Noxval Chrono 333/145 Mg Tablet 10 are:
- Digestive: Feeling sick (nausea) and vomiting; taking it with food may help.
- General and Skin: Increased appetite, weight gain, tremor and hair loss.
- Liver: Report signs of liver problems such as jaundice or unusual tiredness; regular monitoring is essential.
If side effects do not improve or become serious, speak to your doctor right away.
Management Of Side Effects:
Most side effects are temporary and generally harmless and resolve upon discontinuing the use of Noxval Chrono 333/145 Mg Tablet 10. However, if you experience serious side effects or worsening symptoms, please consult your doctor.
Here are some general guidelines for managing common side effects:
- Nausea: Try taking this medicine with food or milk.
- Increased appetite and weight gain: Consider having balanced meals and regular exercise to manage weight gain.
How Noxval Chrono 333/145 Mg Tablet 10 Works?
Noxval Chrono 333/145 Mg Tablet 10 contains sodium valproate (500 mg), which exerts its effects as follows:
- Increases GABA Levels: Valproic acid increases gamma-aminobutyric acid (GABA), a neurotransmitter that inhibits nerve impulses. This action helps reduce excessive electrical activity in the brain.
- Regulates Mood: By increasing GABA levels, sodium valproate also helps regulate mood. This contributes to its effectiveness in managing manic episodes associated with bipolar disorder.
Safety Measures & Warnings
Pregnancy
Noxval Chrono 333/145 Mg Tablet 10 is contraindicated during pregnancy. If you are pregnant or planning to conceive, ensure you discuss this with your doctor before starting this medicine.
Breastfeeding
Noxval Chrono 333/145 Mg Tablet 10 is contraindicated for breastfeeding women. It's essential to consult your doctor to understand the potential risks and benefits.
Alcohol
Mixing alcohol and this medicine might result in enhanced side effects such as dizziness or drowsiness. So, it's advised to avoid or limit alcohol consumption while taking Noxval Chrono 333/145 Mg Tablet 10.
Liver
Caution is advised when taking Noxval Chrono 333/145 Mg Tablet 10 if you have mild to moderate liver impairment. It isn't recommended for severe liver diseases. This medicine may affect liver function.
Kidney
Caution is advised before using Noxval Chrono 333/145 Mg Tablet 10 if you have a history of kidney problems. It's good practice to consult your doctor before taking this medicine.
Use In Driving And Operating Machinery
This medicine may cause dizziness and drowsiness, which can affect your ability to drive or operate machinery. Avoid such activities if you experience these side effects.
Allergy
If you're allergic to sodium valproate or any other ingredients in Noxval Chrono 333/145 Mg Tablet 10, avoid using it. Check the list of ingredients and discuss any known allergies with your doctor.
Children
Caution is advised while giving Noxval Chrono 333/145 Mg Tablet 10 to individuals under 18. Always consult a doctor before giving any medicine to a child.
Older Patients
Older patients should take Noxval Chrono 333/145 Mg Tablet 10 under medical supervision as they can be more susceptible to its side effects. Caution is advised for patients above 70 who might also have liver and kidney issues or might be on other medications. Your doctor will guide you based on your health status.
Interactions of Noxval Chrono 333/145 Mg Tablet 10
Drug-Drug Interactions
Noxval Chrono 333/145 Mg Tablet 10 interacts with the following medicines:
- Antidepressants: Medicines such as fluoxetine or sertraline may interact with this tablet, potentially causing changes in mood or behaviour.
- Anti-epileptics: Certain anti-seizure medicines like phenytoin or carbamazepine may alter their effects when taken with this tablet.
- Blood thinners: Concomitant use of blood-thinning medicines like warfarin with this tablet could increase the risk of bleeding.
Drug-Food Interactions
Certain foods may affect how Noxval Chrono 333/145 Mg Tablet 10 works. These include:
- Grapefruit: This fruit can affect how this tablet is absorbed in your body, potentially altering the medicine's effectiveness.
Drug-Disease Interactions
Noxval Chrono 333/145 Mg Tablet 10 interacts with the following diseases:
- Liver disease: Individuals with liver disease need to be cautious as this medicine could worsen their condition.
- Kidney disease: Caution is advised for people with kidney disease, as this medicine could affect kidney function.
- Mental health disorders: Patients with conditions such as depression may experience worsening of symptoms when taking this medicine.
Dosage of Noxval Chrono 333/145 Mg Tablet 10
Daily Dose
The daily dose of Noxval Chrono 333/145 Mg Tablet 10 should be taken as instructed by your doctor. The dosage may be adjusted based on your specific needs, including the severity of your condition and your response to treatment. Always adhere to the prescribed dosage and do not exceed it without consulting your doctor. For further details regarding dosage, please refer to the package insert.
Over Dose
If you accidentally take more than the prescribed dose of Noxval Chrono 333/145 Mg Tablet 10, you may experience symptoms like nausea, dizziness, and drowsiness. It's important not to panic but to inform your doctor about this.
Missed Dose
If you forget to take a dose of Noxval Chrono 333/145 Mg Tablet 10, take it as soon as you remember. However, if it's nearly time for your next dose, skip the missed one and continue with your regular schedule. Never increase your dosage without consulting your doctor.
Storage
- Store Noxval Chrono 333/145 Mg Tablet 10 in its original packaging at room temperature below 30°C.
- Keep this medicine away from direct light, heat, and moisture.
- Always keep it out of the reach and sight of children.
- Don't forget to use this medicine before its expiry date.
Special Dietary And Lifestyle Recommendation
- If you are managing epilepsy with Noxval Chrono 333/145 Mg Tablet 10, try to maintain a routine with regular sleep patterns. Irregular sleep can trigger seizures.
- For migraine prevention, consider avoiding foods that can trigger migraines, such as aged cheese, chocolate, and processed foods. Regular exercises might also help reduce the frequency and severity of migraines.
Fact Box
| Dosage Forms Available | Tablet |
| Habit Forming | No |
| Ailment | Epilepsy, Bipolar Disorder, Migraine Prophylaxis |
| Drug Category | Anticonvulsant |
| Therapeutic Category | Mood-Stabiliser |
Frequently Asked Questions (FAQs)
What is Noxval Chrono 333/145 Mg Tablet 10 used for?
Noxval Chrono 333/145 Mg Tablet 10 is primarily used to manage epilepsy. This medicine reduces the brain's abnormal electrical activity, helping control seizures.
How should I take Noxval Chrono 333/145 Mg Tablet 10?
You should take this medicine orally, as directed by your doctor. It can be taken with or without food, but it is recommended to take it simultaneously each day.
Can I use this medicine when I am pregnant?
Consult your doctor before using Noxval Chrono 333/145 Mg Tablet 10 if you are pregnant or planning to become pregnant. Your doctor will evaluate the risks and benefits accordingly.
What should I do if I miss a dose?
If you miss a dose of this medicine, take it as soon as you remember. However, if it's nearly time for your next dose, skip the missed dose and continue with your regular schedule.
What are the side effects of Noxval Chrono 333/145 Mg Tablet 10?
Side effects of this medicine may include nausea, vomiting, dizziness, and hair loss. If these side effects persist or worsen, consult your doctor immediately.
Can I consume alcohol while taking this medication?
Avoid consuming alcohol while taking Noxval Chrono 333/145 Mg Tablet 10 as it may increase the risk of side effects such as drowsiness and dizziness.
How should I store this medicine?
Store Noxval Chrono 333/145 Mg Tablet 10 at room temperature below 30°C, away from direct light and moisture. Keep out of reach of children and pets.
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Manufacturer details
Country of origin: INDIA
References
- U.S. Food and Drug Administration. (2008). NDA 22-152/S-000 Chemistry Review(s). Retrieved 1 April 2024, from https://www.accessdata.fda.gov/drugsatfda_docs/nda/2008/022152s000_ChemR.pdf
- Valproic Acid: MedlinePlus Drug Information. (n.d.). https://medlineplus.gov/druginfo/meds/a682412.html
- Website, N. (2024b, April 30). Valproic acid. https://www.nhs.uk/medicines/valproic-acid/
- Rahman, M., Awosika, A. O., & Nguyen, H. (2024, March 19). Valproic Acid. StatPearls - NCBI Bookshelf. https://www.ncbi.nlm.nih.gov/books/NBK559112/
- Valproic acid: Uses, Interactions, Mechanism of Action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB00313
Disclaimer
We, at Truemeds make a diligent attempt to deliver accurate, expert- drafted and thoroughly reviewed medicine related information to our consumers. However, it should, by no means, be considered a substitute for prescription from a certified doctor or a trustworthy doctor-patient relationship. In fact we detest any form of self medication without expert advice. The sole purpose of the information on our portal is to educate our consumers, which helps improve the communication between a doctor and a patient. The information by no means is complete in its entirety and should not be used to diagnose or treat any medical condition. No amount of information can replace the experience and expertise of a doctor, therefore his/her advice always holds priority and should be followed appropriately.
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