Ist 20 MG Tablet 10

Anhox Healthcare Pvt Ltd

Pack of 10 Units

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Old MRP ₹14.28

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Prescription required for this medicine

Store Below 30^o C

Composition

Isoxsuprine (20 Mg)

Ist 20 MG Tablet 10 is used to manage premature labour, a condition where uterine contractions begin before the 37th week of pregnancy. It belongs to a class of medications known as vasodilators and uterine relaxants.

Additionally, this medicine is beneficial for treating various vascular diseases characterised by restricted blood circulation. These include peripheral vascular disease (poor circulation in the limbs), Raynaud's disease (a condition causing decreased blood flow to fingers and toes), and arteriosclerosis obliterans (narrowing of blood vessels due to plaque buildup).

This medicine should be taken as directed by your doctor, with the dosage determined based on your specific condition and response. It is important to inform your doctor about any pre-existing conditions or ongoing medications before beginning this medicine. If you notice any side effects while taking this medicine, notify your doctor immediately. Continue taking the medicine for the duration prescribed by your doctor for optimal results.

Ist 20 MG Tablet 10 is used for the following:

Management of premature labour
Prevention of preterm delivery
Treatment of peripheral vascular disease
Managing Raynaud's disease
Treatment of arteriosclerosis obliterans
Improving blood circulation in vascular disorders
Relaxing uterine muscles during pregnancy complications
Suppressing early labour contractions

Follow these instructions while taking Ist 20 MG Tablet 10:

Swallow the tablet whole with a full glass of water.
Take this medicine with food to reduce stomach upset.
Avoid crushing or chewing the tablet.

Ist 20 MG Tablet 10 is taken orally.

Ist 20 MG Tablet 10 may have the following common side effects:

Nausea
Vomiting
Dizziness
Headache
Palpitations
Tremors

Managing the Side Effects:

Most side effects are temporary and generally harmless and are resolved by discontinuing the use of Ist 20 MG Tablet 10. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

Nausea: Taking Ist 20 MG Tablet 10 with food can help reduce this uncomfortable feeling.
Dizziness: Try taking this medicine at bedtime to minimise the impact of dizziness on your daily activities.

Ist 20 MG Tablet 10 contains isoxsuprine (20 mg), which works on the body as follows:

Beta-Adrenergic Stimulation: Isoxsuprine activates beta-2 receptors in the uterine muscle, causing relaxation and decreased contractility, which helps suppress premature labour contractions.
Smooth Muscle Relaxation: The medicine relaxes the smooth muscles found in the walls of blood vessels, leading to the widening of these vessels and improved blood flow.
Vasodilation: By expanding blood vessels, isoxsuprine increases blood circulation to areas with compromised blood flow, which is particularly beneficial in vascular diseases.
Uterine Contractility Reduction: The medicine decreases the strength and frequency of uterine contractions, helping to prevent preterm delivery in cases of premature labour.

Pregnancy

Ist 20 MG Tablet 10 is used under close medical supervision during pregnancy, specifically to manage premature labour. It should only be taken if clearly needed and as directed by your doctor.

Breastfeeding

Caution is advised while taking Ist 20 MG Tablet 10 if you are breastfeeding. It is best to consult your doctor before taking this medicine.

Alcohol

It is best to avoid alcohol during treatment with this medicine. Alcohol may increase the risk of side effects like dizziness and low blood pressure.

Liver

Caution is advised while taking Ist 20 MG Tablet 10 if you have liver problems. If you have any history of liver disease, inform your doctor before starting this medicine.

Kidney

Caution is advised before using Ist 20 MG Tablet 10 if you have a history of kidney problems. It is a good idea to consult your doctor before taking this medicine.

Using Machines & Driving

Ist 20 MG Tablet 10 may cause dizziness or light-headedness in some people. If you experience these symptoms, avoid driving vehicles or operating heavy machinery until you feel better.

Allergy

If you have any known allergies to isoxsuprine or any ingredients in Ist 20 MG Tablet 10, you should not take this medicine. Inform your doctor about all your allergies before starting treatment.

Children

Caution is advised while giving Ist 20 MG Tablet 10 to children. Always consult your doctor before giving any medicine to a child.

Older Patients

Older patients should take Ist 20 MG Tablet 10 under medical supervision as they may be more sensitive to its effects. Your doctor will guide you based on your health status.

Drug-Drug Interactions

Ist 20 MG Tablet 10 interacts with the following medicines:

Beta-Blockers: Medicines like propranolol or metoprolol may counteract the effects of Ist 20 MG Tablet 10, potentially reducing its effectiveness in improving blood circulation.
Calcium Channel Blockers: When taken with Ist 20 MG Tablet 10, medicines like amlodipine or diltiazem can increase the risk of low blood pressure (hypotension).
Diuretics: Medicines such as furosemide or hydrochlorothiazide used alongside Ist 20 MG Tablet 10 may enhance blood pressure-lowering effects, increasing dizziness risk.
Monoamine Oxidase Inhibitors (MAOIs): Combining Ist 20 MG Tablet 10 with MAOIs like phenelzine or tranylcypromine can increase the risk of dangerous high blood pressure (hypertensive crisis).

Drug-Disease Interactions

Ist 20 MG Tablet 10 interacts with the following diseases:

Coronary Artery Disease: This medicine may worsen symptoms in patients with severe coronary artery disease.
Severe Tachycardia: Ist 20 MG Tablet 10 can increase heart rate, potentially worsening pre-existing rapid heartbeat conditions.
Hyperthyroidism: Patients with overactive thyroid require careful monitoring as Ist 20 MG Tablet 10 may intensify cardiovascular symptoms.
Diabetes: Blood sugar levels may be affected, requiring closer monitoring in diabetic patients.

Daily Dose

The daily dose of Ist 20 MG Tablet 10 should be taken as prescribed by your doctor. The dosage may change based on your condition's severity and how you respond to treatment. Always follow the prescribed dosage and never exceed it without consulting your doctor.

Over Dose

Overdosing on Ist 20 MG Tablet 10 may cause dizziness, nausea, vomiting, headache, palpitations (fast heartbeat), tremors, and nervousness. If you experience these symptoms, contact your doctor for advice.

Missed Dose

If you forget to take a dose, take it as soon as you remember. If it is nearly time for your next dose, skip the missed one and continue with your regular schedule. Never take extra tablets to make up for missed doses.

Store at room temperature (below 30°C) in a dry place.
Keep the medicine in its original packaging, protected from light and moisture.
Keep out of reach of children.
Do not use after the expiry date printed on the package.

Include foods rich in omega-3 fatty acids (like fish and flaxseeds) in your diet to support healthy blood circulation and complement the vasodilatory effects of isoxsuprine.
Regular, gentle exercise such as walking for 20-30 minutes daily can help improve circulation and enhance the effectiveness of Ist 20 MG Tablet 10.

Fact Box

Available Dosage Types	Tablet
Habit Forming	No
Ailment	Premature labour, peripheral vascular disease, Raynaud's disease
Drug Category	Beta-adrenergic agonist
Therapeutic Category	Vasodilator

Can I take Ist 20 MG Tablet 10 during pregnancy?

Ist 20 MG Tablet 10 should only be taken during pregnancy under strict medical supervision when the benefits outweigh the risks. Your doctor will monitor both you and your baby closely.

How does Ist 20 MG Tablet 10 work in the body?

Ist 20 MG Tablet 10 contains isoxsuprine, which relaxes smooth muscles in blood vessels and the uterus. It improves blood flow and reduces uterine contractions by stimulating specific receptors.

What should I do if I miss a dose?

Take the missed dose when you remember. If it is nearly time for your next scheduled dose, skip the missed one and continue your regular schedule. Never double your dose.

Can I stop taking Ist 20 MG Tablet 10 when my symptoms improve?

No, do not stop taking Ist 20 MG Tablet 10 suddenly, as this may cause rebound effects. Always consult your doctor before changing or stopping your medicine.

How should I store Ist 20 MG Tablet 10?

Keep Ist 20 MG Tablet 10 at room temperature (below 30°C) in a dry place away from light and moisture. Store in its original packaging and keep out of children's reach.

Will Ist 20 MG Tablet 10 affect my ability to drive?

Ist 20 MG Tablet 10 may cause dizziness or lightheadedness in some people. Avoid driving or operating machinery until you know how this medicine affects you.

Can I take other medicines alongside Ist 20 MG Tablet 10?

Inform your doctor about all the medicines you are taking. Ist 20 MG Tablet 10 may interact with blood pressure medicines, calcium channel blockers, and certain antidepressants.

Last Updated On 06 Jun. 2025 | 7:30AM (IST)

Certified Content

Written by

Ashmita Borgohain

Medical Content Writer | 13 years

MSc (Applied Genetics)

Reviewed by

Dr. Chhavi Rosha

Medical Content Writer | 9 years

BAMS, FMC, MD Resident

Check out Editorial Policy

Manufacturer details

B-504, 505 , Opposite Gujarat High Court , S.G. High Way, Janta Nagar Kakoldiya Rd, Sola, Ahmedabad, Gujarat 380060

Country of origin: INDIA

Expiry on or after: February 2026

In case of any issues, contact us:

support@truemeds.in|09240250346

Address: 6th floor, Urmi Corporate Park Solaris, Saki Vihar Road, Andheri East, Mumbai 400071

References

DailyMed. (n.d.). Isoxsuprine hydrochloride tablet. U.S. National Library of Medicine. https://dailymed.nlm.nih.gov/dailymed/fda/fdaDrugXsl.cfm?setid=908691b4-7950-4f3e-bbea-ea568fee7ac3 (Accessed 1 April 2025)
DrugBank. (n.d.). Isoxsuprine. https://go.drugbank.com/drugs/DB08941 (Accessed 1 April 2025)
MedlinePlus. (n.d.). Isoxsuprine. https://medlineplus.gov/druginfo/meds/a682831.html (Accessed 1 April 2025)
Abou-Taleb, H. A., Aldosari, B. N., Zaki, R. M., Afzal, O., Tulbah, A. S., Shahataa, M. G., El-Ela, F. I. A., Salem, H. F., & Fouad, A. G. (2023). Formulation and Therapeutic Evaluation of Isoxsuprine-Loaded Nanoparticles against Diabetes-Associated Stroke. Pharmaceutics, 15(9), 2242. https://doi.org/10.3390/pharmaceutics15092242
Jaju, P. B. (2019). Effectiveness and Safety of isoxsuprine hydrochloride as tocolytic Agent in Arresting Active/Threatened Preterm labor and its role in Maintenance tocolysis: A Prospective, Open-Label study. American Journal of Perinatology, 38(03), 291–295. https://doi.org/10.1055/s-0039-1696720

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Disclaimer

We, at Truemeds make a diligent attempt to deliver accurate, expert- drafted and thoroughly reviewed medicine related information to our consumers. However, it should, by no means, be considered a substitute for prescription from a certified doctor or a trustworthy doctor-patient relationship. In fact we detest any form of self medication without expert advice. The sole purpose of the information on our portal is to educate our consumers, which helps improve the communication between a doctor and a patient. The information by no means is complete in its entirety and should not be used to diagnose or treat any medical condition. No amount of information can replace the experience and expertise of a doctor, therefore his/her advice always holds priority and should be followed appropriately.

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